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Functional genetic screens reveal key pathways instructing the molecular phenotypes of tumor-associated macrophages

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1. scibot 23 Apr 2026
  
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  DOI: 10.1158/2326-6066.CIR-25-0488
  
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aacrjournals.org/cancerimmunolres/article/13/12/2054/768330/Functional-Genetic-Screens-Reveal-Key-Pathways
Apr 2026
54.241.53.176 54.241.53.176

cohen-et-al-2026-fibroblast-specialisation-across-microanatomy-in-a-single-cell-atlas-of-human-achilles-tendon-html.html

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54.241.53.176/1c541c0b0c1c157db646e85ccfac5c2eec8fcc2e/cohen-et-al-2026-fibroblast-specialisation-across-microanatomy-in-a-single-cell-atlas-of-human-achilles-tendon-html.html
Mar 2026
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Molecular remodeling of cancer-associated fibroblasts in breast cancer patients receiving anti–PD-1 immunotherapy

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1. scibot 18 Mar 2026
  
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  DOI: 10.3389/fonc.2026.1754311
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12971403/
Jan 2026
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Spatial transcriptomics reveals altered communities and drivers of aberrant epithelia and pro-fibrotic fibroblasts in interstitial lung diseases

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1. scibot 23 Jan 2026
  
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  DOI: 10.1016/j.xgen.2025.101066
  
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sciencedirect.com/science/article/pii/S2666979X25003222
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SLC39A10 drives M2 macrophage polarization and gastric cancer progression through the MAPK14(p38α) pathway

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1. scibot 09 Jan 2026
  
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  DOI: 10.1016/j.isci.2025.114400
  
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sciencedirect.com/science/article/pii/S2589004225026616
Dec 2025
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Intratumoral three-cell-type clusters are a conserved feature of endogenous antitumor immunity

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1. scibot 18 Dec 2025
  
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  DOI: 10.1158/2326-6066.CIR-25-0062
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12707859/
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Dual role of Oct4 and Sox2 in controlling the developmental capacity and timing of tissue morphogenesis in the embryonic lineage

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1. scibot 03 Dec 2025
  
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  DOI: 10.1016/j.devcel.2025.11.003
  
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sciencedirect.com:5037/science/article/pii/S1534580725006951
Oct 2025
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Fibroblast specialisation across microanatomy in a single-cell atlas of healthy human Achilles tendon

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1. scibot 23 Oct 2025
  
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  DOI: 10.1101/2025.10.17.683019
  
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biorxiv.org/content/10.1101/2025.10.17.683019v1
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CD27 agonist antibodies mediate clinical responses through intratumoral stimulation in B-cell malignancies: multicenter RiVa trial

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1. scibot 11 Oct 2025
  
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  DOI: 10.1158/1078-0432.CCR-25-2029
  
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pmc.ncbi.nlm.nih.gov/articles/PMC7618221/
Sep 2025
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Early microglia progenitors colonize the embryonic CNS via integrin-mediated migration from the pial surface

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1. scibot 11 Sep 2025
  
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  DOI: 10.1016/j.devcel.2025.08.012
  
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sciencedirect.com/science/article/pii/S1534580725005325
Jul 2025
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Cellular crosstalk mediated by TGF-β drives epithelial-mesenchymal transition in patient-derived multi-compartment biliary organoids

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1. scibot 22 Jul 2025
  
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  DOI: 10.1038/s41467-025-61442-5
  
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nature.com/articles/s41467-025-61442-5
Jun 2025
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Single-Cell Transcriptomic Landscape Deciphers Intratumoral Heterogeneity and Subtypes of Acral and Mucosal Melanomas

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1. scibot 17 Jun 2025
  
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  DOI: 10.1158/1078-0432.CCR-24-3164
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12163602/
May 2025
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Intratumoral Fusobacterium nucleatum Recruits Tumor-Associated Neutrophils to Promote Gastric Cancer Progression and Immune Evasion

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1. scibot 20 May 2025
  
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  DOI: 10.1158/0008-5472.CAN-24-2580
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12079103/
Feb 2025
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Pharmacological rescue of mutant p53 triggers spontaneous tumor regression via immune responses

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1. scibot 25 Feb 2025
  
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  DOI: 10.1016/j.xcrm.2025.101976
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11970324/
Jul 2024
www.cell.com www.cell.com

Single-cell spatial multiomics reveals tumor microenvironment vulnerabilities in cancer resistance to immunotherapy

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1. scibot 23 Jul 2024
  
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  DOI: 10.1016/j.celrep.2024.114392
  
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cell.com/cell-reports/fulltext/S2211-1247(24)00720-4
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Semaphorin 6D tunes amygdalar circuits for emotional, metabolic, and inflammatory outputs

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1. scibot 17 Jul 2024
  
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  DOI: 10.1016/j.neuron.2024.06.017
  
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sciencedirect.com/science/article/pii/S0896627324004525
Jun 2024
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Tumour microenvironment programming by an RNA–RNA-binding protein complex creates a druggable vulnerability in IDH-wild-type glioblastoma

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1. scibot 20 Jun 2024
  
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  DOI: 10.1038/s41556-024-01428-5
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11178504/
May 2024
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Integrative molecular and spatial analysis reveals evolutionary dynamics and tumor-immune interplay of in situ and invasive acral melanoma

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1. scibot 17 May 2024
  
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  DOI: 10.1016/j.ccell.2024.04.012
  
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sciencedirect.com/science/article/pii/S1535610824001363
Apr 2024
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Identification of hypoxic macrophages in glioblastoma with therapeutic potential for vasculature normalization

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1. scibot 20 Apr 2024
  
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  DOI: 10.1016/j.ccell.2024.03.013
  
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sciencedirect.com/science/article/pii/S1535610824001193
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Single-cell senescence identification reveals senescence heterogeneity, trajectory, and modulators

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1. scibot 11 Apr 2024
  
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  DOI: 10.1016/j.cmet.2024.03.009
  
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sciencedirect.com/science/article/pii/S1550413124000883
Jan 2024
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Integrative analysis of neuroblastoma by single-cell RNA sequencing identifies the NECTIN2-TIGIT axis as a target for immunotherapy

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1. scibot 11 Jan 2024
  
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  DOI: 10.1016/j.ccell.2023.12.008
  
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  DOI: 10.1016/j.ccell.2023.12.008
  
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sciencedirect.com/science/article/pii/S1535610823004361
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An exhausted-like microglial population accumulates in aged and APOE4 genotype Alzheimer’s brains

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1. scibot 06 Jan 2024
  
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  DOI: 10.1016/j.immuni.2023.12.001
  
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sciencedirect.com:5037/science/article/pii/S1074761323005320
May 2023
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Single-cell transcriptomics reveals immune suppression and cell states predictive of patient outcomes in rhabdomyosarcoma

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1. scibot 30 May 2023
  
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  DOI: 10.1038/s41467-023-38886-8
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10224926/
Jan 2023
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SSRN-id4236792-html.html

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1. scibot 14 Jan 2023
  
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  DOI: 10.2139/ssrn.4236792
  
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52.53.155.43/f804482cc7cebef00c72524b3620589e015133ca/SSRN-id4236792-html.html
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Intratumoral Heterogeneity and Immune Modulation in Lung Adenocarcinoma in Female Smokers and Never Smokers

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1. scibot 12 Jan 2023
  
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  DOI: 10.1158/0008-5472.CAN-21-3836
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9437562/
Nov 2022
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Tumor-intrinsic SIRPA promotes sensitivity to checkpoint inhibition immunotherapy in melanoma

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1. scibot 04 Nov 2022
  
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  DOI: 10.1016/j.ccell.2022.10.012
  
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sciencedirect.com/science/article/pii/S1535610822005037
Oct 2022
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Motor neurons use push-pull signals to direct vascular remodeling critical for their connectivity

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1. scibot 18 Oct 2022
  
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  DOI: 10.1016/j.neuron.2022.09.021
  
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cell.com/neuron/fulltext/S0896-6273(22)00860-1
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Decoding the colorectal cancer ecosystem emphasizes the cooperative role of cancer cells, TAMs and CAFsin tumor progression

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1. scibot 11 Oct 2022
  
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  DOI: 10.1186/s12967-022-03661-8
  
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link.springer.com/article/10.1186/s12967-022-03661-8
Aug 2022
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CXCR4high megakaryocytes regulate host-defense immunity against bacterial pathogens

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1. scibot 22 Aug 2022
  
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  DOI: 10.7554/eLife.78662
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9374440/
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Single-cell and spatial mapping Identify cell types and signaling Networks in the human ureter

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1. scibot 02 Aug 2022
  
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  DOI: 10.1016/j.devcel.2022.07.004
  
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sciencedirect.com/science/article/pii/S1534580722004932
Jul 2022
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Group 3 innate lymphocytes make a distinct contribution to Type 17 immunity in bladder defence

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1. scibot 09 Jul 2022
  
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  DOI: 10.1016/j.isci.2022.104660
  
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sciencedirect.com/science/article/pii/S2589004222009324
May 2022
aacrjournals.org aacrjournals.org

Genomic and single-cell landscape reveals novel drivers and therapeutic vulnerabilities of transformed cutaneous T-cell lymphomaGenomic and single-cell landscape of transformed CTCL

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1. scibot 13 May 2022
  
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  DOI: 10.1158/2159-8290.CD-21-1207
  
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aacrjournals.org/cancerdiscovery/article/12/5/1294/694564/Genomic-and-Single-Cell-Landscape-Reveals-Novel
Apr 2022
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Single-cell atlas of the aging mouse colon

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1. scibot 21 Apr 2022
  
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  DOI: 10.1016/j.isci.2022.104202
  
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sciencedirect.com/science/article/pii/S2589004222004722
Feb 2022
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Single-cell analysis of human glioma and immune cells identifies S100A4 as an immunotherapy target

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1. scibot 17 Feb 2022
  
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  DOI: 10.1038/s41467-022-28372-y
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8828877/
Nov 2021
elifesciences.org elifesciences.org

Intraocular dendritic cells characterize HLA-B27-associated acute anterior uveitis

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1. scibot 19 Nov 2021
  
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  RRID:SCR_017054
  
  DOI: 10.7554/eLife.67396
  
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elifesciences.org/articles/67396
Jul 2021
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Macrophage-tumor cell interaction promotes ATRT progression and chemoresistance

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1. scibot 31 Jul 2021
  
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  DOI: 10.1007/s00401-019-02116-7
  
  Resource: CellPhoneDB (RRID:SCR_017054)
  
  Curator: @Naa003
  
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link.springer.com/article/10.1007/s00401-019-02116-7
Jun 2021
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Single-cell transcriptomics defines heterogeneity of epicardial cells and fibroblasts within the infarcted murine heart

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1. scibot 26 Jun 2021
  
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  RRID:SCR_017054
  
  DOI: 10.7554/eLife.65921
  
  Resource: CellPhoneDB (RRID:SCR_017054)
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8216715/
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Follicular lymphoma triggers phenotypic and functional remodeling of the human lymphoid stromal cell landscape

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1. scibot 24 Jun 2021
  
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  RRID:SCR_017054
  
  DOI: 10.1016/j.immuni.2021.05.019
  
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sciencedirect.com/science/article/pii/S1074761321002259
May 2021
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Reticular Fibroblasts Expressing the Transcription Factor WT1 Define a Stromal Niche That Maintains and Replenishes Splenic Red Pulp Macrophages

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1. scibot 06 May 2021
  
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  RRID:SCR_017054
  
  DOI: 10.1016/j.immuni.2020.06.008
  
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sciencedirect.com/science/article/pii/S1074761320302387
Apr 2021
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Single-Cell Transcriptomics Reveals Early Emergence of Liver Parenchymal and Non-parenchymal Cell Lineages

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1. scibot 24 Apr 2021
  
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  RRID:SCR_017054
  
  DOI: 10.1016/j.cell.2020.09.012
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7643810/
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Immunogenomic Landscape of Hematological Malignancies

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1. scibot 17 Apr 2021
  
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  RRID:SCR_017054
  
  DOI: 10.1016/j.ccell.2020.06.002
  
  Resource: CellPhoneDB (RRID:SCR_017054)
  
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sciencedirect.com/science/article/pii/S1535610820302750
Mar 2021
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Short-term exposure to intermittent hypoxia leads to changes in gene expression seen in chronic pulmonary disease

1
1. scibot 04 Mar 2021
  
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  RRID:SCR_017054
  
  DOI: 10.7554/eLife.63003
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7909952/
Feb 2021
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Single-cell landscape of the ecosystem in early-relapse hepatocellular carcinoma

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1. scibot 27 Feb 2021
  
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  RRID:SCR_017054
  
  DOI: 10.1016/j.cell.2020.11.041
  
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sciencedirect.com/science/article/pii/S0092867420316135