63 Matching Annotations
  1. Aug 2025
  2. www.nature.com www.nature.com
    Thymic epithelial cells amplify epigenetic noise to promote immune tolerance
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    nature.com/articles/s41586-025-09424-x
  3. Jul 2025
  4. www.nature.com www.nature.com
    NNMT inhibition in cancer-associated fibroblasts restores antitumour immunity
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    nature.com/articles/s41586-025-09303-5
  5. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A universal chimeric antigen receptor (CAR)–fragment antibody binder (FAB) split system for cancer immunotherapy
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC12227065/
  6. Jun 2025
  7. www.nature.com www.nature.com
    Radiation-induced amphiregulin drives tumour metastasis
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    nature.com/articles/s41586-025-08994-0
  8. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Targeting DTX2/UFD1-mediated FTO degradation to regulate antitumor immunity
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC11665913/
  9. 52.53.155.43 52.53.155.43
    PDF-html.html
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    52.53.155.43/bf0f2a9c147624ca7b182a2a5608426c90ea27fc/PDF-html.html
  10. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The Mediator Kinase Module regulates cell cycle re-entry and transcriptional responses following DNA damage
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC12139960/
  11. www.pnas.org www.pnas.org
    Conformation-specific synthetic intrabodies modulate mTOR signaling with subcellular spatial resolution
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    pnas.org/doi/10.1073/pnas.2424679122
  12. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Integrative genomic analysis of DLBCL identifies immune environments associated with bispecific antibody response
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC12163739/
  13. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Multiplex gene editing models of del(7q) reveal combined CUX1 and EZH2 loss drives clonal expansion and drug resistance
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    pmc.ncbi.nlm.nih.gov/articles/PMC12067884/
  14. May 2025
  15. www.sciencedirect.com www.sciencedirect.com
    Mammalian queuosine tRNA modification impacts translation to enhance cell proliferation and MHC-II expression
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    sciencedirect.com/science/article/pii/S0022283625002542
  16. Apr 2025
  17. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    CAR Treg synergy with anti-CD154 promotes infectious tolerance and dictates allogeneic heart transplant acceptance
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC11981628/
  18. www.nature.com www.nature.com
    Mapping the extracellular molecular architecture of the pAg-signaling complex with α-Butyrophilin antibodies
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    nature.com/articles/s41598-025-94347-w
  19. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    High Glucose Contribution to the TCA Cycle Is a Feature of Aggressive Non–Small Cell Lung Cancer in Patients
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC11962397/
  20. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Targeting the dendritic cell-secreted immunoregulatory cytokine CCL22 alleviates radioresistance
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC11444901/
  21. Mar 2025
  22. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Feedback control of the heat shock response by spatiotemporal regulation of Hsp70
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    pmc.ncbi.nlm.nih.gov/articles/PMC11415305/
  23. www.science.org www.science.org
    Regulatory T cells constrain T cells of shared specificity to enforce tolerance during infection
    1
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    science.org/doi/10.1126/science.adk3248
  24. www.biorxiv.org www.biorxiv.org
    Emergent 3D genome reorganization from the stepwise assembly of transcriptional condensates
    1
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    biorxiv.org/content/10.1101/2025.02.23.639564v1
  25. Dec 2024
  26. www.sciencedirect.com www.sciencedirect.com
    Sonopermeation With Size-sorted Microbubbles Synergistically Increases Survival and Enhances Tumor Apoptosis With L-DOX by Increasing Vascular Permeability and Perfusion in Neuroblastoma Xenografts
    1
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    sciencedirect.com/science/article/pii/S0301562924004101
  27. www.biorxiv.org www.biorxiv.org
    Molecular characterization of the archaic HLA-B*73:01 allele reveals presentation of a unique peptidome and skewed engagement by KIR2DL2
    1
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    biorxiv.org/content/10.1101/2024.11.25.625330v1
  28. Nov 2024
  29. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    TGF-β promotes the postselection thymic development and peripheral function of interferon-γ- producing iNKT cells
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC10592054/
  30. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Radiotherapy Enhances Metastasis Through Immune Suppression by Inducing PD-L1 and MDSC in Distal Sites
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC11062826/
  31. Oct 2024
  32. www.biorxiv.org www.biorxiv.org
    Efficacy and limitations of combined A2.CAR Treg and anti-CD154 therapy in a mouse model of haplo-mismatched heart transplantation
    1
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    biorxiv.org/content/10.1101/2024.09.20.614149v1
  33. Sep 2024
  34. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Unraveling the Role of Bromodomain and Extra-Terminal Proteins in Human Uterine Leiomyosarcoma
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC11394028/
  35. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Pregnancy dedifferentiates memory CD8+ T cells into hypofunctional cells with exhaustion-enriched programs
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC11383355/
  36. Jul 2024
  37. link.springer.com link.springer.com
    Targeting Bromodomain-Containing Protein 9 in Human Uterine Fibroid Cells
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    link.springer.com/article/10.1007/s43032-024-01608-6
  38. Apr 2024
  39. www.sciencedirect.com www.sciencedirect.com
    Batf3+ DCs and the 4-1BB/4-1BBL axis are required at the effector phase in the tumor microenvironment for PD-1/PD-L1 blockade efficacy
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    sciencedirect.com/science/article/pii/S2211124724004698
  40. www.nature.com www.nature.com
    PU.1 and BCL11B sequentially cooperate with RUNX1 to anchor mSWI/SNF to poise the T cell effector landscape
    1
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    nature.com/articles/s41590-024-01807-y
  41. Feb 2024
  42. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Feedback control of the heat shock response by spatiotemporal regulation of Hsp70
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC10802473/
  43. Jan 2024
  44. www.nature.com www.nature.com
    Loss of thymocyte competition underlies the tumor suppressive functions of the E2a transcription factor in T-ALL
    1
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    nature.com/articles/s41375-023-02123-4
  45. www.sciencedirect.com www.sciencedirect.com
    Low Affinity CD8+ T Cells Provide Interclonal Help to High Affinity CD8+ T Cells to Augment Alloimmunity
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    sciencedirect.com/science/article/pii/S160061352400073X
  46. www.mdpi.com www.mdpi.com
    Bromodomain-Containing Protein 9 Regulates Signaling Pathways and Reprograms the Epigenome in Immortalized Human Uterine Fibroid Cells
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    mdpi.com/1422-0067/25/2/905
  47. Nov 2023
  48. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Heterogeneity in allospecific T cell function in transplant-tolerant hosts determines susceptibility to rejection following infection
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC10617766/
  49. Aug 2023
  50. 52.53.155.43 52.53.155.43
    Bromodomain Containing 9 Regulates Signaling Pathways and Reprograms the Epigenome in Human Uterine Fibroid Cells
    1
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    52.53.155.43/0d1eedff7a58f6e635f082ef0f4c0fef026770f9/preprints202307.1154.v1-html.html
  51. Jun 2023
  52. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Pancreatic tumors exhibit myeloid-driven amino acid stress and upregulate arginine biosynthesis
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC10260022/
  53. May 2023
  54. www.mdpi.com www.mdpi.com
    The Functional Role and Regulatory Mechanism of FTO m6A RNA Demethylase in Human Uterine Leiomyosarcoma
    1
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    mdpi.com/1422-0067/24/9/7957
  55. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Pregnancy programs epigenetic and transcriptional exhaustion in memory CD8+ T cells
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC10104270/
  56. www.biorxiv.org www.biorxiv.org
    Loss of thymocyte competition underlies the tumor suppressive functions of the E2a transcription factor in T lymphocyte acute lymphoblastic leukemia
    1
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    biorxiv.org/content/10.1101/2023.04.23.537993v1
  57. Apr 2023
  58. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Site of vulnerability on SARS-CoV-2 spike induces broadly protective antibody against antigenically distinct Omicron subvariants
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC10104900/
  59. Mar 2023
  60. insight.jci.org insight.jci.org
    Cancer-associated mesothelial cell-derived ANGPTL4 and STC1 promote the early steps of ovarian cancer metastasis
    1
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    insight.jci.org/articles/view/163019
  61. Feb 2023
  62. www.nature.com www.nature.com
    The endogenous repertoire harbors self-reactive CD4+ T cell clones that adopt a follicular helper T cell-like phenotype at steady state
    1
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    nature.com/articles/s41590-023-01425-0
  63. www.nature.com www.nature.com
    Oncogenic RAS promotes leukemic transformation of CUX1-deficient cells
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    nature.com/articles/s41388-023-02612-x
  64. Oct 2022
  65. www.nature.com www.nature.com
    Zinc cyclic di-AMP nanoparticles target and suppress tumours via endothelial STING activation and tumour-associated macrophage reinvigoration
    1
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    nature.com/articles/s41565-022-01225-x
  66. www.pnas.org www.pnas.org
    Reduced Satb1 expression predisposes CD4+ T conventional cells to Treg suppression and promotes transplant survival
    1
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    pnas.org/doi/10.1073/pnas.2205062119
  67. Sep 2022
  68. www.jci.org www.jci.org
    Host-versus-commensal immune responses participate in the rejection of colonized solid organ transplants
    1
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    jci.org/articles/view/153403
  69. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Moderate Low UVB Irradiation Modulates Tumor-associated Macrophages and Dendritic Cells and Promotes Anti-tumor Immunity in Tumor-bearing Mice
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    onlinelibrary.wiley.com/doi/10.1111/php.13684
  70. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Loss of a 7q gene, CUX1, disrupts epigenetically driven DNA repair and drives therapy-related myeloid neoplasms
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC8414261/
  71. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Epistatic drift causes gradual decay of predictability in protein evolution
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    ncbi.nlm.nih.gov/pmc/articles/PMC9429997/
  72. Aug 2022
  73. 52.53.155.43 52.53.155.43
    153403.1-20220712133551-covered-e0fd13ba177f913fd3156f593ead4cfd-html.html
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    52.53.155.43/ef841bf914b91e9f1a682dd059d4bdb4b13c63d7/153403.1-20220712133551-covered-e0fd13ba177f913fd3156f593ead4cfd-html.html
  74. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Tcf-1 promotes genomic instability and T cell transformation in response to aberrant β-catenin activation
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC9371646/
  75. Jun 2022
  76. www.science.org www.science.org
    Epistatic drift causes gradual decay of predictability in protein evolution
    1
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    science.org/doi/10.1126/science.abn6895
  77. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Oral Alloantigen Exposure Promotes Donor-specific Tolerance in a Mouse Model of Minor-Mismatched Skin Transplantation
    1
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    onlinelibrary.wiley.com/doi/10.1111/ajt.17107
  78. May 2022
  79. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genetic ancestry effects on the response to viral infection are pervasive but cell type-specific
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC8957271/
  80. Apr 2022
  81. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Oncogenic and Tumor Suppressor Functions for Lymphoid Enhancer Factor 1 in E2a-/- T Acute Lymphoblastic Leukemia
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC8971981/
  82. Jan 2022
  83. www.nature.com www.nature.com
    CRISPR screening in human hematopoietic stem and progenitor cells reveals an enrichment for tumor suppressor genes within chromosome 7 commonly deleted regions
    1
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    nature.com/articles/s41375-021-01491-z
  84. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genomic studies controvert the existence of the CUX1 p75 isoform
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC8741762/
  85. Dec 2021
  86. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    All-trans retinoic acid overcomes solid tumor radioresistance by inducing inflammatory macrophages
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    ncbi.nlm.nih.gov/pmc/articles/PMC8550472/
  87. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cross-Neutralization of Emerging SARS-CoV-2 Variants of Concern by Antibodies Targeting Distinct Epitopes on Spike
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    ncbi.nlm.nih.gov/pmc/articles/PMC8593667/
  88. Nov 2021
  89. journals.asm.org journals.asm.org
    Cross-Neutralization of Emerging SARS-CoV-2 Variants of Concern by Antibodies Targeting Distinct Epitopes on Spike
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    journals.asm.org/doi/abs/10.1128/mBio.02975-21
  90. Sep 2021
  91. www.sciencedirect.com www.sciencedirect.com
    Effector T cell responses unleashed by regulatory T cell ablation exacerbate oral squamous cell carcinoma
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    sciencedirect.com/science/article/pii/S2666379121002573
  92. Aug 2021
  93. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cross neutralization of emerging SARS-CoV-2 variants of concern by antibodies targeting distinct epitopes on spike
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    ncbi.nlm.nih.gov/pmc/articles/PMC8312900/
  94. May 2021
  95. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Profiling B cell immunodominance after SARS-CoV-2 infection reveals antibody evolution to non-neutralizing viral targets
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    ncbi.nlm.nih.gov/pmc/articles/PMC8101792/