77 Matching Annotations
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    Acellular Adipose Tissue promotes anti-fibrotic remodeling in Phase II Study
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  3. Feb 2026
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    Inhibition of focal adhesion kinase impairs tumor formation and preserves hearing in a murine model of NF2-related schwannomatosis
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    science.org/doi/10.1126/sciadv.ady8382
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    Nivolumab and Relatlimab for the treatment of patients with unresectable or metastatic mismatch repair proficient colorectal cancer
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    Inhibition of focal adhesion kinase impairs tumor formation and preserves hearing in a murine model of NF2-related schwannomatosis
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    B cell-intrinsic IL-2 signaling regulates inflammation by promoting IL-10 expression in CD25+ age-associated B cells
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  9. Jan 2026
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    System-wide profiling reveals metabolic alterations in a G2019S LRRK2 knockin mouse model of Parkinson’s disease: systemic depletion of pyrimidine nucleosides
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  11. Dec 2025
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    Intratumoral three-cell-type clusters are a conserved feature of endogenous antitumor immunity
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  14. Oct 2025
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    Internalized SNCA/α-synuclein fibrils become truncated and resist degradation in neurons while glial cells rapidly degrade SNCA fibrils
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    Interactions Between Ploidy and Resource Availability Shape Clonal Evolution in Glioblastoma
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  17. Sep 2025
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    Development of a First-in-Class Click Chemistry–Based Cancer Therapeutic, from Preclinical Evaluation to a First-in-Human Dose Escalation Clinical Trial
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  19. Aug 2025
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    SCAnED - An Open-source Skin Segmentation Macro for Semi-automated Cell and Nuclei Detection in Epidermal and Dermal Skin Compartments
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  21. Jul 2025
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    Asynchronous aging and turnover of human circulating and tissue-resident memory T cells across sites
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    Siglec ligand immunohistochemistry reveals association with immune exclusion and survival
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    P4HA1 Mediates Hypoxia-Induced Invasion in Human Pancreatic Cancer Organoids
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  28. May 2025
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    Cell-death pathways and tau-associated neuronal vulnerability in Alzheimer’s disease
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  31. Apr 2025
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    Activated immune infiltrates expand opportunities for targeted therapy in p53-abnormal endometrial carcinoma
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    Pan-KRAS Inhibitors BI-2493 and BI-2865 Display Potent Antitumor Activity in Tumors with KRAS Wild-type Allele Amplification
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  34. Mar 2025
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    Single-cell transcriptomic and functional studies identify glial state changes and a role for inflammatory RIPK1 signaling in ALS pathogenesis
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    Phase I Trial of TTI-101, a First-in-Class Oral Inhibitor of STAT3, in Patients with Advanced Solid Tumors
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  38. Feb 2025
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    Metabolic imaging distinguishes ovarian cancer subtypes and detects their early and variable responses to treatment
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    Targeting insulin-like growth factor 1 receptor restricts development and severity of secondary lymphedema in mice
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    Platinum-based chemotherapy induces opposing effects on immunotherapy response-related spatial and stromal biomarkers in the bladder cancer microenvironment
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  42. Jan 2025
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    Activation of δ-opioid receptors blocks allodynia in a model of headache induced by PACAP
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  46. www.cell.com www.cell.com
    Cell therapy with human IL-10-producing ILC2s limits xenogeneic graft-versus-host disease by inhibiting pathogenic T cell responses
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  47. Oct 2024
  48. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Redirecting B7-H3.CAR T cells to Chemokines Expressed in Osteosarcoma Enhances Homing and Antitumor Activity in Preclinical Models
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  49. Sep 2024
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    Multiplexed Spatial Profiling of Hodgkin Reed–Sternberg Cell Neighborhoods in Classic Hodgkin Lymphoma
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  51. Aug 2024
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    Multiplex Spatial Omics Reveals Changes in Immune-Epithelial Crosstalk During Inflammation and Dysplasia Development in Chronic IBD Patients
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  56. Jul 2024
  57. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Adult-onset deletion of ATP13A2 in mice induces progressive nigrostriatal pathway dopaminergic degeneration and lysosomal abnormalities
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    CYRI-B-mediated macropinocytosis drives metastasis via lysophosphatidic acid receptor uptake
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  59. May 2024
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    PABPC1L induces IDO1 to promote tryptophan metabolism and immune suppression in renal cell carcinoma
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    Combined CDK4/6 and ERK1/2 inhibition enhances anti-tumor activity in NF1-associated plexiform neurofibroma
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  62. Apr 2024
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    NIBR-LTSi is a selective LATS kinase inhibitor activating YAP signaling and expanding tissue stem cells in vitro and in vivo
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  64. Mar 2024
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    Female mice display sex-specific differences in cerebrovascular function and subarachnoid haemorrhage-induced injury
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  66. Feb 2024
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    Imaging Glioblastoma Response to Radiotherapy Using 2H Magnetic Resonance Spectroscopy Measurements of Fumarate Metabolism.
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    Imaging glioblastoma response to radiotherapy using 2H magnetic resonance spectroscopy measurements of fumarate metabolism
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  69. Jan 2024
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    Ventral pallidum neurons projecting to the ventral tegmental area reinforce but do not invigorate reward-seeking behavior
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  71. Dec 2023
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    A cluster of neuropeptide S neurons regulates breathing and arousal
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  73. Nov 2023
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    The bone transcription factor Osterix controls extracellular matrix- and node of Ranvier-related gene expression in oligodendrocytes
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  75. Oct 2023
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    IL-1R1 signaling in TBI: assessing chronic impacts and neuroinflammatory dynamics in a mouse model of mild closed-head injury
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  77. Aug 2023
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    Circulating and intratumoral immune determinants of response to atezolizumab plus bevacizumab in patients with variant histology or sarcomatoid renal cell carcinoma
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  79. Jun 2023
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    Kv7/KCNQ potassium channels in cortical hyperexcitability and juvenile seizure-related death in Ank2-mutant mice
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  81. May 2023
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  83. Apr 2023
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    CX3CR1 deficiency-induced TIL tumor restriction as a novel addition for CAR-T design in solid malignancies
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  85. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Liposome-Encapsulated Eribulin Shows Enhanced Antitumor Activity over Eribulin for Combination Therapy with Anti–PD-1 Antibody
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  86. Mar 2023
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    Apolipoprotein E induces pathogenic senescent-like myeloid cells in prostate cancer
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  88. Oct 2022
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    Imaging glioblastoma response to radiotherapy using 2H magnetic resonance spectroscopy measurements of fumarate metabolism
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  90. Sep 2022
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    Biological misinterpretation of transcriptional signatures in tumor samples can unknowingly undermine mechanistic understanding and faithful alignment with preclinical data
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    Metronomic cyclophosphamide is more effective than a single dose in resistant tumours Cyclophosphamide depletes tumour infiltrating T regulatory cells and combined with anti-PD-1 therapy improves survival in murine neuroblastoma
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  93. Jul 2022
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    Sensory neurons display cell-type-specific vulnerability to loss of neuron-glia interactions
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    Aberrant expression and subcellular localization of ECT2 drives colorectal cancer progression and growth
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  96. Jun 2022
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    Comprehensive surfaceome profiling to identify and validate novel cell-surface targets in osteosarcoma
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  98. May 2022
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    Single cell characterization of the cellular landscape of acral melanoma identifies novel targets for immunotherapy
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  100. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Intra-Tumoral CD8+ T-Cell Infiltration and PD-L1 Positivity in Homologous Recombination Deficient Pancreatic Ductal Adenocarcinoma
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  101. Dec 2021
  102. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    STING regulates peripheral nerve regeneration and colony stimulating factor 1 receptor (CSF1R) processing in microglia
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  103. Nov 2021
  104. elifesciences.org elifesciences.org
    Localization of KRAS downstream target ARL4C to invasive pseudopods accelerates pancreatic cancer cell invasion
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    Autotaxin impedes anti-tumor immunity by suppressing chemotaxis and tumor infiltration of CD8+ T cells
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  106. Oct 2021
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    Transcriptional and functional divergence in lateral hypothalamic glutamate neurons projecting to the lateral habenula and ventral tegmental area
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  108. Sep 2021
  109. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Expression of T-cell Exhaustion Molecules and Human Endogenous Retroviruses as Predictive Biomarkers for response to Nivolumab in Metastatic Clear Cell Renal Cell Carcinoma
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  110. May 2021
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    RIPK1 activation mediates neuroinflammation and disease progression in multiple sclerosis
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  112. Jan 2021
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    Monomeric/dimeric forms of Fgf15/FGF19 show differential activity in hepatocyte proliferation and metabolic function
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    faseb.onlinelibrary.wiley.com/doi/10.1096/fj.202002203R
  114. Dec 2020
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    Baricitinib treatment resolves lower-airway macrophage inflammation and neutrophil recruitment in SARS-CoV-2-infected rhesus macaques
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