65 Matching Annotations
  1. Last 7 days
  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Development of a First-in-Class Click Chemistry–Based Cancer Therapeutic, from Preclinical Evaluation to a First-in-Human Dose Escalation Clinical Trial
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    pmc.ncbi.nlm.nih.gov/articles/PMC12402790/
  3. Aug 2025
  4. app.jove.com app.jove.com
    SCAnED - An Open-source Skin Segmentation Macro for Semi-automated Cell and Nuclei Detection in Epidermal and Dermal Skin Compartments
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    app.jove.com/t/68746/scaned-an-open-source-skin-segmentation-macro-for-semi-automated-cell
  5. Jul 2025
  6. www.sciencedirect.com www.sciencedirect.com
    Asynchronous aging and turnover of human circulating and tissue-resident memory T cells across sites
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    sciencedirect.com/science/article/pii/S1074761325003103
  7. 52.53.155.43 52.53.155.43
    2025.07.08.659146v1.full-html.html
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    52.53.155.43/67583f71085d67e773095e1c49bf994b7d6a060e/2025.07.08.659146v1.full-html.html
  8. Jun 2025
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    Siglec ligand immunohistochemistry reveals association with immune exclusion and survival
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    sciencedirect.com/science/article/pii/S0023683725001138
  11. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    P4HA1 Mediates Hypoxia-Induced Invasion in Human Pancreatic Cancer Organoids
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    pmc.ncbi.nlm.nih.gov/articles/PMC12123483/
  12. May 2025
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    Cell-death pathways and tau-associated neuronal vulnerability in Alzheimer’s disease
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  15. Apr 2025
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    Activated immune infiltrates expand opportunities for targeted therapy in p53-abnormal endometrial carcinoma
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    pathsocjournals.onlinelibrary.wiley.com/doi/10.1002/path.6429
  17. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Pan-KRAS Inhibitors BI-2493 and BI-2865 Display Potent Antitumor Activity in Tumors with KRAS Wild-type Allele Amplification
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    pmc.ncbi.nlm.nih.gov/articles/PMC11962398/
  18. Mar 2025
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    Single-cell transcriptomic and functional studies identify glial state changes and a role for inflammatory RIPK1 signaling in ALS pathogenesis
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    sciencedirect.com/science/article/pii/S1074761325000913
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  21. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Phase I Trial of TTI-101, a First-in-Class Oral Inhibitor of STAT3, in Patients with Advanced Solid Tumors
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    pmc.ncbi.nlm.nih.gov/articles/PMC11911802/
  22. Feb 2025
  23. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Metabolic imaging distinguishes ovarian cancer subtypes and detects their early and variable responses to treatment
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    pmc.ncbi.nlm.nih.gov/articles/PMC11850285/
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    Targeting insulin-like growth factor 1 receptor restricts development and severity of secondary lymphedema in mice
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    sciencedirect.com/science/article/pii/S2589004225002081
  25. aacrjournals.org aacrjournals.org
    Platinum-based chemotherapy induces opposing effects on immunotherapy response-related spatial and stromal biomarkers in the bladder cancer microenvironment
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    aacrjournals.org/clincancerres/article/30/18/4227/747456/Platinum-Based-Chemotherapy-Induces-Opposing
  26. Jan 2025
  27. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    Activation of δ-opioid receptors blocks allodynia in a model of headache induced by PACAP
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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.17424
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  29. Dec 2024
  30. www.cell.com www.cell.com
    Cell therapy with human IL-10-producing ILC2s limits xenogeneic graft-versus-host disease by inhibiting pathogenic T cell responses
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    cell.com/cell-reports/fulltext/S2211-1247(24)01453-0
  31. Oct 2024
  32. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Redirecting B7-H3.CAR T cells to Chemokines Expressed in Osteosarcoma Enhances Homing and Antitumor Activity in Preclinical Models
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    ncbi.nlm.nih.gov/pmc/articles/PMC11443211/
  33. Sep 2024
  34. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Multiplexed Spatial Profiling of Hodgkin Reed–Sternberg Cell Neighborhoods in Classic Hodgkin Lymphoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC11369618/
  35. Aug 2024
  36. www.sciencedirect.com www.sciencedirect.com
    Multiplex Spatial Omics Reveals Changes in Immune-Epithelial Crosstalk During Inflammation and Dysplasia Development in Chronic IBD Patients
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    Mutant TP53 switches therapeutic vulnerability during gastric cancer progression within interleukin-6 family cytokines
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  38. journals.lww.com journals.lww.com
    Generation and Characterization of Ex Vivo Expanded... : Journal of Immunotherapy
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  39. www.cell.com www.cell.com
    Single-cell spatial multiomics reveals tumor microenvironment vulnerabilities in cancer resistance to immunotherapy
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    cell.com/cell-reports/fulltext/S2211-1247(24)00720-4
  40. Jul 2024
  41. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Adult-onset deletion of ATP13A2 in mice induces progressive nigrostriatal pathway dopaminergic degeneration and lysosomal abnormalities
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    ncbi.nlm.nih.gov/pmc/articles/PMC11271504/
  42. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CYRI-B-mediated macropinocytosis drives metastasis via lysophosphatidic acid receptor uptake
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    ncbi.nlm.nih.gov/pmc/articles/PMC11219039/
  43. May 2024
  44. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PABPC1L induces IDO1 to promote tryptophan metabolism and immune suppression in renal cell carcinoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC11094425/
  45. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Combined CDK4/6 and ERK1/2 inhibition enhances anti-tumor activity in NF1-associated plexiform neurofibroma
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    ncbi.nlm.nih.gov/pmc/articles/PMC11060649/
  46. Apr 2024
  47. www.sciencedirect.com www.sciencedirect.com
    NIBR-LTSi is a selective LATS kinase inhibitor activating YAP signaling and expanding tissue stem cells in vitro and in vivo
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  48. Mar 2024
  49. www.thelancet.com www.thelancet.com
    Female mice display sex-specific differences in cerebrovascular function and subarachnoid haemorrhage-induced injury
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    thelancet.com/journals/ebiom/article/PIIS2352-3964(24)00093-8/abstract
  50. Feb 2024
  51. 52.53.155.43 52.53.155.43
    Imaging Glioblastoma Response to Radiotherapy Using 2H Magnetic Resonance Spectroscopy Measurements of Fumarate Metabolism.
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    Imaging glioblastoma response to radiotherapy using 2H magnetic resonance spectroscopy measurements of fumarate metabolism
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    aacrjournals.org/cancerres/article/82/19/3622/709416/Imaging-Glioblastoma-Response-to-Radiotherapy
  53. Jan 2024
  54. www.sciencedirect.com www.sciencedirect.com
    Ventral pallidum neurons projecting to the ventral tegmental area reinforce but do not invigorate reward-seeking behavior
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    sciencedirect.com/science/article/pii/S2211124723016807
  55. Dec 2023
  56. www.sciencedirect.com www.sciencedirect.com
    A cluster of neuropeptide S neurons regulates breathing and arousal
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    sciencedirect.com/science/article/pii/S0960982223015324
  57. Nov 2023
  58. www.sciencedirect.com www.sciencedirect.com
    The bone transcription factor Osterix controls extracellular matrix- and node of Ranvier-related gene expression in oligodendrocytes
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    sciencedirect.com/science/article/pii/S089662732300764X
  59. Oct 2023
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    IL-1R1 signaling in TBI: assessing chronic impacts and neuroinflammatory dynamics in a mouse model of mild closed-head injury
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    link.springer.com/article/10.1186/s12974-023-02934-3
  61. Aug 2023
  62. dx.doi.org dx.doi.org
    Circulating and intratumoral immune determinants of response to atezolizumab plus bevacizumab in patients with variant histology or sarcomatoid renal cell carcinoma
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    dx.doi.org/10.1158/2326-6066.CIR-22-0996
  63. Jun 2023
  64. www.nature.com www.nature.com
    Kv7/KCNQ potassium channels in cortical hyperexcitability and juvenile seizure-related death in Ank2-mutant mice
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    nature.com/articles/s41467-023-39203-z
  65. May 2023
  66. 52.53.155.43 52.53.155.43
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  67. Apr 2023
  68. www.sciencedirect.com www.sciencedirect.com
    CX3CR1 deficiency-induced TIL tumor restriction as a novel addition for CAR-T design in solid malignancies
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    sciencedirect.com/science/article/pii/S2589004223005205
  69. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Liposome-Encapsulated Eribulin Shows Enhanced Antitumor Activity over Eribulin for Combination Therapy with Anti–PD-1 Antibody
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    ncbi.nlm.nih.gov/pmc/articles/PMC10068443/
  70. Mar 2023
  71. www.sciencedirect.com www.sciencedirect.com
    Apolipoprotein E induces pathogenic senescent-like myeloid cells in prostate cancer
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    sciencedirect.com/science/article/pii/S1535610823000326
  72. Oct 2022
  73. aacrjournals.org aacrjournals.org
    Imaging glioblastoma response to radiotherapy using 2H magnetic resonance spectroscopy measurements of fumarate metabolism
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    aacrjournals.org/cancerres/article/82/19/3622/709416/Imaging-Glioblastoma-Response-to-Radiotherapy
  74. Sep 2022
  75. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Biological misinterpretation of transcriptional signatures in tumor samples can unknowingly undermine mechanistic understanding and faithful alignment with preclinical data
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    ncbi.nlm.nih.gov/pmc/articles/PMC9475248/
  76. www.sciencedirect.com www.sciencedirect.com
    Metronomic cyclophosphamide is more effective than a single dose in resistant tumours Cyclophosphamide depletes tumour infiltrating T regulatory cells and combined with anti-PD-1 therapy improves survival in murine neuroblastoma
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  77. Jul 2022
  78. www.sciencedirect.com www.sciencedirect.com
    Sensory neurons display cell-type-specific vulnerability to loss of neuron-glia interactions
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    sciencedirect.com/science/article/pii/S2211124722009366
  79. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Aberrant expression and subcellular localization of ECT2 drives colorectal cancer progression and growth
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    ncbi.nlm.nih.gov/pmc/articles/PMC9056178/
  80. Jun 2022
  81. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Comprehensive surfaceome profiling to identify and validate novel cell-surface targets in osteosarcoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC9167717/
  82. May 2022
  83. aacrjournals.org aacrjournals.org
    Single cell characterization of the cellular landscape of acral melanoma identifies novel targets for immunotherapy
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    aacrjournals.org/clincancerres/article/28/10/2131/694823/Single-cell-Characterization-of-the-Cellular
  84. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Intra-Tumoral CD8+ T-Cell Infiltration and PD-L1 Positivity in Homologous Recombination Deficient Pancreatic Ductal Adenocarcinoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC9082359/
  85. Dec 2021
  86. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    STING regulates peripheral nerve regeneration and colony stimulating factor 1 receptor (CSF1R) processing in microglia
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    ncbi.nlm.nih.gov/pmc/articles/PMC8633968/
  87. Nov 2021
  88. elifesciences.org elifesciences.org
    Localization of KRAS downstream target ARL4C to invasive pseudopods accelerates pancreatic cancer cell invasion
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    elifesciences.org/articles/66721
  89. www.sciencedirect.com www.sciencedirect.com
    Autotaxin impedes anti-tumor immunity by suppressing chemotaxis and tumor infiltration of CD8+ T cells
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  90. Oct 2021
  91. www.sciencedirect.com www.sciencedirect.com
    Transcriptional and functional divergence in lateral hypothalamic glutamate neurons projecting to the lateral habenula and ventral tegmental area
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    sciencedirect.com/science/article/pii/S0896627321006930
  92. Sep 2021
  93. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Expression of T-cell Exhaustion Molecules and Human Endogenous Retroviruses as Predictive Biomarkers for response to Nivolumab in Metastatic Clear Cell Renal Cell Carcinoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC8443005/
  94. May 2021
  95. www.sciencedirect.com www.sciencedirect.com
    RIPK1 activation mediates neuroinflammation and disease progression in multiple sclerosis
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  96. Jan 2021
  97. faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com
    Monomeric/dimeric forms of Fgf15/FGF19 show differential activity in hepatocyte proliferation and metabolic function
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    faseb.onlinelibrary.wiley.com/doi/10.1096/fj.202002203R
  98. Dec 2020
  99. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Baricitinib treatment resolves lower-airway macrophage inflammation and neutrophil recruitment in SARS-CoV-2-infected rhesus macaques
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    ncbi.nlm.nih.gov/pmc/articles/PMC7654323/