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    H3K27M drives OPC stemness and intrathecal therapeutic vulnerability in brainstem glioma organoids
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    sciencedirect.com/science/article/pii/S1934590926003139
  3. Sep 2026
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    Single-cell transcriptomic atlas of the human fetal uveal tract reveals heterogeneity in melanocyte populations
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    sciencedirect.com/science/article/pii/S2589004226028890
  5. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A pancreatic cancer organoid-macrophage co-culture using starPEG-heparin hydrogel deciphers tumor-immune cell interactions
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    VISTA+ Neutrophils Contribute to Platinum Resistance by Suppressing CD8+ T Cells in High-Grade Serous Ovarian Cancer
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  7. Aug 2026
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    Impact of vitamin D on the colon cancer immune microenvironment: results of a randomized clinical trial of preoperative vitamin D supplementation in patients with stage I-III colon cancer
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    Temporal Genomic Analysis of Homogeneous Tumor Models Reveals Key Regulators of Immune Evasion in Melanoma
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  10. Jul 2026
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    Spatial transcriptomic analysis reveals spatial features in human Stanford type A aortic dissection
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    Inhibiting Fatty Acid Oxidation Reverses Autophagy-Mediated Acquired Chemotherapy Resistance in Pancreatic Ductal Adenocarcinoma
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  13. May 2026
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    Patient-derived organoids from metastatic colorectal cancer mirror tumor heterogeneity and predict patient survival and drug sensitivity
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    Identification of a distinct cluster of LY6E+ macrophages in esophageal squamous cell carcinoma: functional phenotype, spatial interaction, and prognostic significance
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    nature.com/articles/s41416-026-03456-4
  16. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    JIN-A02, a Mutant-Selective Fourth-Generation EGFR inhibitor, Overcomes C797S-Mediated Resistance and Demonstrates Intracranial Activity in NSCLC
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  17. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Adenosine A2B Receptor Promotes Tumor Progression and Metastases in Undifferentiated Pleomorphic Sarcoma
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  18. Apr 2026
  19. aacrjournals.org aacrjournals.org
    Activation of T cell-intrinsic p53 by acetylation elicits antitumor immunity to boost cancer immunotherapy
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    aacrjournals.org/cancerdiscovery/article/16/1/155/771238/Activation-of-T-Cell-Intrinsic-p53-by-Acetylation
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    SpaHE-Infil: A spatial heterogeneity framework for decoding TME infiltration from H&E-stained slides
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    pmc.ncbi.nlm.nih.gov/articles/PMC13068657/
  21. Mar 2026
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    Tumor vessel phenotype in colorectal cancer microenvironment according to age at diagnosis
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  23. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Ectopic CD11c Drives SMAD3-Mediated Aberrant Antigen Presentation and Epithelial–Mesenchymal Transition in Esophageal Squamous Cell Carcinoma
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    Targeting peptidyl-arginine deiminase 4 suppresses SARS-CoV-2 replication and modulates the inflammatory response
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  25. Feb 2026
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    Acellular Adipose Tissue promotes anti-fibrotic remodeling in Phase II Study
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    Phenotypic Characterization and Prognostic Impact of CD103+ Tissue-Resident Memory T Cells in Diffuse Large B-cell Lymphoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC12865361/
  28. Jan 2026
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    Altered hepatic metabolism in Down syndrome
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  30. Dec 2025
  31. www.sciencedirect.com:5037 www.sciencedirect.com:5037
    An IL-12 partial agonist sustains intratumoral lymphocyte activation and detoxifies systemic IL-12 therapy
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    Intratumoral three-cell-type clusters are a conserved feature of endogenous antitumor immunity
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    Immunocompetent murine models recapitulate the heterogeneous tumor immune microenvironment of human liposarcoma
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  34. Nov 2025
  35. www.biorxiv.org www.biorxiv.org
    Single-cell quantification of senescence burden reveals cell type-specific ageing dynamics across organs
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    Soluble TIM-3 and galectin-9 predict survival in gastric and gastroesophageal junction cancer
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    Intratumoral regulatory T cells are associated with treatment response to neoadjuvant chemotherapy and prognosis in gastroesophageal adenocarcinoma
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  38. Sep 2025
  39. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Cemiplimab in locally advanced or metastatic secondary angiosarcomas (CEMangio): A phase II clinical trial and biomarker analyses
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    Elevated Transglutaminase-2 in SOX10-Deficient Melanoma Promotes Tumor Onset and Decreases Intratumoral CD4+ T Cells
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  41. Aug 2025
  42. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Integrative analyses of single-cell and bulk RNA sequencing reveal tumour microenvironment features associated with neoadjuvant immunochemotherapy response in oesophageal squamous cell carcinoma
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    onlinelibrary.wiley.com/doi/10.1002/ctd2.70080
  43. Jul 2025
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  45. May 2025
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  47. Apr 2025
  48. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The Impact of the Tumor Microenvironment on the Effect of IL-1β Blockade in NSCLC: Biomarker Analyses from CANOPY-1 and CANOPY-N Trials
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  49. Mar 2025
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  52. Jan 2025
  53. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Complement Factor H Is an ICOS Ligand Modulating Tregs in the Glioma Microenvironment
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    pmc.ncbi.nlm.nih.gov/articles/PMC11712038/
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    The Tumor Immune Microenvironment and Therapeutic Efficacy of Trastuzumab Deruxtecan in Gastric Cancer
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    Endocrine-targeting therapies shift the breast microbiome to reduce estrogen receptor-α breast cancer risk
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  57. Dec 2024
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  59. Nov 2024
  60. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Spatial Multiomics Reveals Intratumoral Immune Heterogeneity with Distinct Cytokine Networks in Lung Cancer Brain Metastases
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    pmc.ncbi.nlm.nih.gov/articles/PMC11539001/
  61. Aug 2024
  62. journals.lww.com journals.lww.com
    Generation and Characterization of Ex Vivo Expanded... : Journal of Immunotherapy
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  63. Jul 2024
  64. www.cell.com www.cell.com
    Single-cell spatial multiomics reveals tumor microenvironment vulnerabilities in cancer resistance to immunotherapy
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  65. May 2024
  66. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Discovery of a novel potent EGFR inhibitor against EGFR activating mutations and on-target resistance in NSCLC
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    Immunotherapy-activated T cells recruit and skewlate-stage activated M1-like macrophagesthat are critical for therapeutic efficacy
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    sciencedirect.com/science/article/pii/S1535610824001351
  68. Apr 2024
  69. www.sciencedirect.com www.sciencedirect.com
    NIBR-LTSi is a selective LATS kinase inhibitor activating YAP signaling and expanding tissue stem cells in vitro and in vivo
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  70. Mar 2024
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    Phototruncation cell tracking with near-infrared photoimmunotherapy using heptamethine cyanine dye to visualise migratory dynamics of immune cells
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  72. Jan 2024
  73. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Lethal severe fever with thrombocytopenia syndrome virus infection causes systemic germinal centre failure and massive T cell apoptosis in cats
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  74. Oct 2023
  75. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Colorectal Cancer Organoid–Stroma Biobank Allows Subtype-Specific Assessment of Individualized Therapy Responses
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  76. Aug 2023
  77. dx.doi.org dx.doi.org
    Circulating and intratumoral immune determinants of response to atezolizumab plus bevacizumab in patients with variant histology or sarcomatoid renal cell carcinoma
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    dx.doi.org/10.1158/2326-6066.CIR-22-0996
  78. Jul 2023
  79. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Near-Infrared Photoimmunotherapy Targeting Podoplanin-Expressing Cancer Cells and Cancer-Associated Fibroblasts
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  80. Jun 2023
  81. dx.doi.org dx.doi.org
    Precision cut lung slices as a preclinical model for non-small cell lung cancer chemoprevention
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    dx.doi.org/10.1158/1940-6207.CAPR-23-0004
  82. May 2023
  83. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Patterns of Oncogene Coexpression at Single-Cell Resolution Influence Survival in Lymphoma
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  84. Apr 2023
  85. www.sciencedirect.com www.sciencedirect.com
    Synergistic effects of combined immunotherapy strategies in a model of multifocal hepatocellular carcinoma
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  86. Dec 2022
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  88. Oct 2022
  89. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The immune microenvironment landscape shows treatment-specific differences in rectal cancer patients
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    ncbi.nlm.nih.gov/pmc/articles/PMC9552175/
  90. May 2022
  91. aacrjournals.org aacrjournals.org
    Single cell characterization of the cellular landscape of acral melanoma identifies novel targets for immunotherapy
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    aacrjournals.org/clincancerres/article/28/10/2131/694823/Single-cell-Characterization-of-the-Cellular
  92. Jan 2022
  93. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Nedd9 restrains autophagy to limit growth of early stage non-small cell lung cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC8277748/
  94. Dec 2021
  95. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Clinical Response to Anti-CD47 Immunotherapy Is Associated with Rapid Reduction of Exhausted Bystander CD4+ BTLA+ T Cells in Tumor Microenvironment of Mycosis Fungoides
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  96. Nov 2021
  97. mct.aacrjournals.org mct.aacrjournals.org
    Simultaneously Combined Cancer Cell- and CTLA4-Targeted NIR-PIT Causes a Synergistic Treatment Effect in Syngeneic Mouse Models
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    mct.aacrjournals.org/content/20/11/2262
  98. Sep 2021
  99. link.springer.com link.springer.com
    The pivotal role of cytotoxic NK cells in mediating the therapeutic effect of anti-CD47 therapy in mycosis fungoides
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    link.springer.com/article/10.1007/s00262-021-03051-x
  100. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Expression of T-cell Exhaustion Molecules and Human Endogenous Retroviruses as Predictive Biomarkers for response to Nivolumab in Metastatic Clear Cell Renal Cell Carcinoma
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  101. Jun 2021
  102. www.nature.com www.nature.com
    MicroRNA-200c restoration reveals a cytokine profile to enhance M1 macrophage polarization in breast cancer
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    nature.com/articles/s41523-021-00273-1
  103. May 2021
  104. clincancerres.aacrjournals.org clincancerres.aacrjournals.org
    G9a Inhibition Enhances Checkpoint Inhibitor Blockade Response in Melanoma
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    clincancerres.aacrjournals.org/content/27/9/2624