82 Matching Annotations
  1. Oct 2025
  2. www.sciencedirect.com www.sciencedirect.com
    Arsenic regulates ALKBH1 abundance and substrate specificity to promote translation and tumorigenicity
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    sciencedirect.com/science/article/pii/S2211124725010824
  3. Sep 2025
  4. www.biorxiv.org www.biorxiv.org
    Vitamin D3 ameliorates R-loop-induced replication stress and chromosomal instability in MED12-mutant uterine fibroids
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    biorxiv.org/content/10.1101/2025.09.17.676564v1
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    Tumor nutrient stress gives rise to a drug tolerant cell state in pancreatic cancer
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    biorxiv.org/content/10.1101/2025.09.04.673818v1
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    Early-life gut microbiome maturity regulates blood–brain barrier and cognitive development
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    tandfonline.com/doi/abs/10.1080/19490976.2025.2551879
  7. Aug 2025
  8. www.nature.com www.nature.com
    Thymic epithelial cells amplify epigenetic noise to promote immune tolerance
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    nature.com/articles/s41586-025-09424-x
  9. www.medrxiv.org www.medrxiv.org
    Adapting Clinical Chemistry Plasma as a Source for Liquid Biopsies
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    medrxiv.org/content/10.1101/2025.08.13.25333564v1
  10. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Oxygen-induced stress reveals context-specific gene regulatory effects in human brain organoids
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    pmc.ncbi.nlm.nih.gov/articles/PMC12315710/
  11. Jul 2025
  12. www.nature.com www.nature.com
    NNMT inhibition in cancer-associated fibroblasts restores antitumour immunity
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    nature.com/articles/s41586-025-09303-5
  13. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A universal chimeric antigen receptor (CAR)–fragment antibody binder (FAB) split system for cancer immunotherapy
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    pmc.ncbi.nlm.nih.gov/articles/PMC12227065/
  14. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Spatially Varying Selection Amplifies Intrapopulation Differentiation Among Phenotypic Traits in the Rocky‐Shore Mussel, Mytilus californianus
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    pmc.ncbi.nlm.nih.gov/articles/PMC12207488/
  15. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Direct inhibition of tumor hypoxia response with synthetic transcriptional repressors
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    pmc.ncbi.nlm.nih.gov/articles/PMC12206482/
  16. Jun 2025
  17. www.nature.com www.nature.com
    Radiation-induced amphiregulin drives tumour metastasis
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    nature.com/articles/s41586-025-08994-0
  18. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Comparative transcriptomics of iPSC-derived cardiomyocytes in a high and a low altitude population
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    pmc.ncbi.nlm.nih.gov/articles/PMC12157700/
  19. 52.53.155.43 52.53.155.43
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  20. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The Mediator Kinase Module regulates cell cycle re-entry and transcriptional responses following DNA damage
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    pmc.ncbi.nlm.nih.gov/articles/PMC12139960/
  21. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    PARP-1 as a novel target in endocrine-resistant breast cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12168341/
  22. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Genetic, developmental, and neural changes underlying the evolution of butterfly mate preference
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    pmc.ncbi.nlm.nih.gov/articles/PMC12136153/
  23. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Multiplex gene editing models of del(7q) reveal combined CUX1 and EZH2 loss drives clonal expansion and drug resistance
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    pmc.ncbi.nlm.nih.gov/articles/PMC12067884/
  24. May 2025
  25. 52.53.155.43 52.53.155.43
    zqaf020-html.html
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  26. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Liver portal fibroblasts induce the functions of primary human hepatocytes in vitro
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    pmc.ncbi.nlm.nih.gov/articles/PMC12064700/
  27. Apr 2025
  28. elifesciences.org elifesciences.org
    Microenvironmental arginine restriction sensitizes pancreatic cancers to polyunsaturated fatty acids by suppression of lipid synthesis
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    elifesciences.org/reviewed-preprints/106492
  29. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Microenvironmental arginine restriction sensitizes pancreatic cancers to polyunsaturated fatty acids by suppression of lipid synthesis
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    pmc.ncbi.nlm.nih.gov/articles/PMC11952453/
  30. Mar 2025
  31. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A shared gene but distinct dynamics regulate mimicry polymorphisms in closely related species
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    pmc.ncbi.nlm.nih.gov/articles/PMC11908123/
  32. www.science.org www.science.org
    Regulatory T cells constrain T cells of shared specificity to enforce tolerance during infection
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    science.org/doi/10.1126/science.adk3248
  33. www.biorxiv.org www.biorxiv.org
    Emergent 3D genome reorganization from the stepwise assembly of transcriptional condensates
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    biorxiv.org/content/10.1101/2025.02.23.639564v1
  34. Nov 2024
  35. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Radiotherapy Enhances Metastasis Through Immune Suppression by Inducing PD-L1 and MDSC in Distal Sites
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    pmc.ncbi.nlm.nih.gov/articles/PMC11062826/
  36. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    TGF-β promotes the postselection thymic development and peripheral function of interferon-γ- producing iNKT cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC10592054/
  37. Sep 2024
  38. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Oxygen-induced stress reveals context-specific gene regulatory effects in human brain organoids
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    ncbi.nlm.nih.gov/pmc/articles/PMC11398411/
  39. journals.lww.com journals.lww.com
    Long-term HBV infection of engineered cultures of induced... : Hepatology Communications
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    journals.lww.com/hepcomm/fulltext/2024/08010/long_term_hbv_infection_of_engineered_cultures_of.12.aspx
  40. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Unraveling the Role of Bromodomain and Extra-Terminal Proteins in Human Uterine Leiomyosarcoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC11394028/
  41. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Validation studies and multi-omics analysis of Zhx2 as a candidate quantitative trait gene underlying brain oxycodone metabolite (oxymorphone) levels and behavior
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    ncbi.nlm.nih.gov/pmc/articles/PMC11383981/
  42. Aug 2024
  43. www.pnas.org www.pnas.org
    Reduced Satb1 expression predisposes CD4+ T conventional cells to Treg suppression and promotes transplant survival
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    pnas.org/doi/10.1073/pnas.2205062119
  44. Jul 2024
  45. link.springer.com link.springer.com
    Targeting Bromodomain-Containing Protein 9 in Human Uterine Fibroid Cells
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    link.springer.com/article/10.1007/s43032-024-01608-6
  46. Jun 2024
  47. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CUX1 regulates human hematopoietic stem cell chromatin accessibility via the BAF complex
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    ncbi.nlm.nih.gov/pmc/articles/PMC11163479/
  48. Apr 2024
  49. www.nature.com www.nature.com
    PU.1 and BCL11B sequentially cooperate with RUNX1 to anchor mSWI/SNF to poise the T cell effector landscape
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    nature.com/articles/s41590-024-01807-y
  50. Mar 2024
  51. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The endogenous Mtv8 locus and the immunoglobulin repertoire
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    ncbi.nlm.nih.gov/pmc/articles/PMC10948529/
  52. Feb 2024
  53. www.mdpi.com www.mdpi.com
    Transcriptomic Analysis of Postnatal Rat Carotid Body Development
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    mdpi.com/2073-4425/15/3/302
  54. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Supergene evolution via gain of auto-regulation
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    ncbi.nlm.nih.gov/pmc/articles/PMC10802445/
  55. Jan 2024
  56. www.nature.com www.nature.com
    Loss of thymocyte competition underlies the tumor suppressive functions of the E2a transcription factor in T-ALL
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    nature.com/articles/s41375-023-02123-4
  57. www.mdpi.com www.mdpi.com
    Bromodomain-Containing Protein 9 Regulates Signaling Pathways and Reprograms the Epigenome in Immortalized Human Uterine Fibroid Cells
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    mdpi.com/1422-0067/25/2/905
  58. link.springer.com link.springer.com
    Transcriptomic signatures of individual cell types in cerebral cavernous malformation
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    link.springer.com/article/10.1186/s12964-023-01301-2
  59. Dec 2023
  60. www.nature.com www.nature.com
    ERα/PR crosstalk is altered in the context of the ERα Y537S mutation and contributes to endocrine therapy-resistant tumor proliferation
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    nature.com/articles/s41523-023-00601-7
  61. www.biorxiv.org www.biorxiv.org
    The endogenous Mtv8 locus and the immunoglobulin repertoire
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    biorxiv.org/content/10.1101/2023.11.24.567955v1
  62. Oct 2023
  63. link.springer.com link.springer.com
    Antisense oligonucleotide-based targeting of Tau-tubulin kinase 1 prevents hippocampal accumulation of phosphorylated tau in PS19 tauopathy mice
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    link.springer.com/article/10.1186/s40478-023-01661-3
  64. Sep 2023
  65. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Gut microbes and the liver circadian clock partition glucose and lipid metabolism
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    ncbi.nlm.nih.gov/pmc/articles/PMC10503806/
  66. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genome-wide Mapping Implicates 5-Hydroxymethylcytosines in Diabetes Mellitus and Alzheimer’s Disease
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    ncbi.nlm.nih.gov/pmc/articles/PMC10490934/
  67. academic.oup.com academic.oup.com
    Acute and Long-Term Consequences of Co-opted doublesex on the Development of Mimetic Butterfly Color Patterns
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    academic.oup.com/mbe/article/40/9/msad196/7260046
  68. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    TGFβ signaling links early life endocrine-disrupting chemicals exposure to suppression of nucleotide excision repair in rat myometrial stem cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC10492698/
  69. www.nature.com www.nature.com
    Kunitz-type protease inhibitor TFPI2 remodels stemness and immunosuppressive tumor microenvironment in glioblastoma
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    nature.com/articles/s41590-023-01605-y
  70. Aug 2023
  71. 52.53.155.43 52.53.155.43
    Bromodomain Containing 9 Regulates Signaling Pathways and Reprograms the Epigenome in Human Uterine Fibroid Cells
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    52.53.155.43/0d1eedff7a58f6e635f082ef0f4c0fef026770f9/preprints202307.1154.v1-html.html
  72. Jun 2023
  73. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    TGFβ signaling links early-life endocrine-disrupting chemicals exposure to suppression of nucleotide excision repair in rat myometrial stem cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC10274956/
  74. www.sciencedirect.com www.sciencedirect.com
    Epithelial tissue confinement inhibits cell growth and leads to volume-reducing divisions
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    sciencedirect.com/science/article/pii/S1534580723002666
  75. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Pancreatic tumors exhibit myeloid-driven amino acid stress and upregulate arginine biosynthesis
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    ncbi.nlm.nih.gov/pmc/articles/PMC10260022/
  76. May 2023
  77. www.mdpi.com www.mdpi.com
    The Functional Role and Regulatory Mechanism of FTO m6A RNA Demethylase in Human Uterine Leiomyosarcoma
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    mdpi.com/1422-0067/24/9/7957
  78. www.biorxiv.org www.biorxiv.org
    Loss of thymocyte competition underlies the tumor suppressive functions of the E2a transcription factor in T lymphocyte acute lymphoblastic leukemia
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    biorxiv.org/content/10.1101/2023.04.23.537993v1
  79. Apr 2023
  80. journals.plos.org journals.plos.org
    Polyamines and eIF5A hypusination facilitate SREBP2 synthesis and cholesterol production leading to enhanced enterovirus attachment and infection
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    journals.plos.org/plospathogens/article
  81. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Site of vulnerability on SARS-CoV-2 spike induces broadly protective antibody against antigenically distinct Omicron subvariants
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    ncbi.nlm.nih.gov/pmc/articles/PMC10104900/
  82. www.mdpi.com www.mdpi.com
    VEGF Induces Expression of Genes That Either Promote or Limit Relaxation of the Retinal Endothelial Barrier
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    mdpi.com/1422-0067/24/7/6402
  83. Feb 2023
  84. www.nature.com www.nature.com
    Oncogenic RAS promotes leukemic transformation of CUX1-deficient cells
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    nature.com/articles/s41388-023-02612-x
  85. Nov 2022
  86. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Asymmetrical forward and reverse developmental trajectories determine molecular programs of B cell antigen receptor editing
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    ncbi.nlm.nih.gov/pmc/articles/PMC9636592/
  87. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SARS-CoV-2 Diverges from Other Betacoronaviruses in Only Partially Activating the IRE1α/XBP1 Endoplasmic Reticulum Stress Pathway in Human Lung-Derived Cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC9600248/
  88. Oct 2022
  89. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Evolution of immune genes is associated with the Black Death
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  90. Sep 2022
  91. journals.asm.org journals.asm.org
    SARS-CoV-2 Diverges from Other Betacoronaviruses in Only Partially Activating the IRE1α/XBP1 Endoplasmic Reticulum Stress Pathway in Human Lung-Derived Cells
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    journals.asm.org/doi/10.1128/mbio.02415-22
  92. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Loss of a 7q gene, CUX1, disrupts epigenetically driven DNA repair and drives therapy-related myeloid neoplasms
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    ncbi.nlm.nih.gov/pmc/articles/PMC8414261/
  93. Aug 2022
  94. www.sciencedirect.com www.sciencedirect.com
    NF-κB memory coordinates transcriptional responses to dynamic inflammatory stimuli
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    sciencedirect.com/science/article/pii/S2211124722009688
  95. Jul 2022
  96. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    https://biorxiv.org/cgi/content/10.1101/2021.12.30.474519
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    ncbi.nlm.nih.gov/pmc/articles/PMC9275661/
  97. May 2022
  98. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genetic ancestry effects on the response to viral infection are pervasive but cell type-specific
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    ncbi.nlm.nih.gov/pmc/articles/PMC8957271/
  99. journals.plos.org journals.plos.org
    Dnmt1a is essential for gene body methylation and the regulation of the zygotic genome in a wasp
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    journals.plos.org/plosgenetics/article
  100. www.science.org www.science.org
    Cannabidiol inhibits SARS-CoV-2 replication through induction of the host ER stress and innate immune responses
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    science.org/doi/10.1126/sciadv.abi6110
  101. Apr 2022
  102. insight.jci.org insight.jci.org
    Mutant ANP induces mitochondrial and ion channel remodeling in a human iPSC–derived atrial fibrillation model
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    insight.jci.org/articles/view/155640
  103. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Oncogenic and Tumor Suppressor Functions for Lymphoid Enhancer Factor 1 in E2a-/- T Acute Lymphoblastic Leukemia
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    ncbi.nlm.nih.gov/pmc/articles/PMC8971981/
  104. Mar 2022
  105. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Control of spinal motor neuron terminal differentiation through sustained Hoxc8 gene activity
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    ncbi.nlm.nih.gov/pmc/articles/PMC8940177/
  106. Jan 2022
  107. www.nature.com www.nature.com
    CRISPR screening in human hematopoietic stem and progenitor cells reveals an enrichment for tumor suppressor genes within chromosome 7 commonly deleted regions
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    nature.com/articles/s41375-021-01491-z
  108. Dec 2021
  109. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cross-Neutralization of Emerging SARS-CoV-2 Variants of Concern by Antibodies Targeting Distinct Epitopes on Spike
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    ncbi.nlm.nih.gov/pmc/articles/PMC8593667/
  110. Nov 2021
  111. journals.asm.org journals.asm.org
    Cross-Neutralization of Emerging SARS-CoV-2 Variants of Concern by Antibodies Targeting Distinct Epitopes on Spike
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    journals.asm.org/doi/abs/10.1128/mBio.02975-21
  112. Oct 2021
  113. genomebiology.biomedcentral.com genomebiology.biomedcentral.com
    Benchmarking sequencing methods and tools that facilitate the study of alternative polyadenylation
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    genomebiology.biomedcentral.com/articles/10.1186/s13059-021-02502-z
  114. Aug 2021
  115. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cross neutralization of emerging SARS-CoV-2 variants of concern by antibodies targeting distinct epitopes on spike
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    ncbi.nlm.nih.gov/pmc/articles/PMC8312900/
  116. May 2021
  117. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Profiling B cell immunodominance after SARS-CoV-2 infection reveals antibody evolution to non-neutralizing viral targets
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    ncbi.nlm.nih.gov/pmc/articles/PMC8101792/
  118. Apr 2021
  119. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    https://biorxiv.org/cgi/content/10.1101/2021.03.10.432967
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    ncbi.nlm.nih.gov/pmc/articles/PMC7987002/