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    Pharmacologically targeting CDK12 induces BRCAness and synergizes with merestinib to exacerbate DNA damage in high-risk neuroblastoma
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    sciencedirect.com/science/article/pii/S2211124726010752
  3. May 2026
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    A human iPSC-derived sensory neuron platform for high-throughput discovery of neuroprotectants against chemotherapy-induced peripheral neuropathy
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    sciencedirect.com/science/article/pii/S2666379126002041
  5. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Lipid Composition Alters Ferroptosis Sensitivity
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    pmc.ncbi.nlm.nih.gov/articles/PMC13138121/
  6. Mar 2026
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    The myeloid SRC family kinase HCK regulates breast cancer growth by activating tumor-associated macrophage-led invasion and inhibiting cytotoxic T cell activity
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  8. Feb 2026
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    Identification of CADM1 as an Immunotherapeutic Target and Evaluation of a Novel CADM1-Targeting Antibody-Drug Conjugate in Preclinical Osteosarcoma Models
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  10. Dec 2025
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    KRT81 promotes metastasis of colorectal cancer by acting as a protein scaffold for ezrin
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    Pan-cancer analysis of oncogenic MET fusions reveals distinct pathogenomic subsets with differential sensitivity to MET-targeted therapy
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  13. Nov 2025
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    An Fc-Engineered Glycomodified Antibody Supports Proinflammatory Activation of Immune Effector Cells and Restricts Progression of Breast Cancer
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  15. Sep 2025
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    Adaptive Therapy Exploits Fitness Deficits in Chemotherapy-Resistant Ovarian Cancer to Achieve Long-Term Tumor Control
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  17. Aug 2025
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    Differential control of growth and identity by HNF4α isoforms in pancreatic ductal adenocarcinoma
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  19. Jun 2025
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    Cisplatin-Induced APE2 Overexpression Disrupts MYH9 Function and Causes Hearing Loss
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    Cancer selective cell death induction by a bivalent CK2 inhibitor targeting the ATP site and the allosteric αD pocket
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  25. Apr 2025
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    N6-methyladenosine in DNA promotes genome stability
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    BCL-XL Protects ASS1-Deficient Cancers from Arginine Starvation–Induced Apoptosis
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  28. Mar 2025
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    Single-cell transcriptomic and functional studies identify glial state changes and a role for inflammatory RIPK1 signaling in ALS pathogenesis
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  30. Feb 2025
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    Targeting GPC2 on intraocular and CNS metastatic retinoblastomas with local and systemic delivery of CAR T-cells
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  33. Oct 2024
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    PKMYT1 Is a Marker of Treatment Response and a Therapeutic Target for CDK4/6 Inhibitor-Resistance in ER+ Breast Cancer
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  35. Sep 2024
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    Coagulation factor X promotes resistance to androgen-deprivation therapy in prostate cancer
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    A chemical screen identifies PRMT5 as a therapeutic vulnerability for paclitaxel-resistant triple-negative breast cancer
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  38. Aug 2024
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    Proteo-metabolomics and patient tumor slice experiments point to amino acid centrality for rewired mitochondria in fibrolamellar carcinoma
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  40. Jul 2024
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    PAI-1 uncouples integrin-β1 from restrain by membrane-bound β-catenin to promote collagen fibril remodeling in obesity-related neoplasms
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  42. Jun 2024
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    Small-Molecule Inhibition of CBX4/7 Hypersensitises Homologous Recombination-Impaired Cancer to Radiation by Compromising CtIP-Mediated DNA End Resection
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  44. May 2024
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    Development of chromosome 1q+ specific treatment for highest risk pediatric posterior fossa ependymoma
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    The RIPK1 death domain restrains ZBP1- and TRIF-mediated cell death and inflammation
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  47. Dec 2023
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    Analysis of the Contribution of 6-mer Seed Toxicity to HIV-1-Induced Cytopathicity
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  49. Nov 2023
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    Cleaved caspase-3 is present in the majority of glial cells in the intact rat spinal cord during postnatal life
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  51. Jun 2023
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    Analysis of the Contribution of 6-mer Seed Toxicity to HIV-1-Induced Cytopathicity
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    The CD73 immune checkpoint promotes tumor cell metabolic fitness
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  54. May 2023
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    AKT activation because of PTEN loss upregulates xCT via GSK3β/NRF2, leading to inhibition of ferroptosis in PTEN-mutant tumor cells
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    BAP1 loss is associated with higher ASS1 expression in epithelioid mesothelioma: implications for therapeutic stratification.
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  57. Apr 2023
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    USP9X mediates an acute adaptive response to MAPK suppression in pancreatic cancer but creates multiple actionable therapeutic vulnerabilities
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  59. Mar 2023
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    Apolipoprotein E induces pathogenic senescent-like myeloid cells in prostate cancer
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  61. Feb 2023
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    CRISPR-based large-scale modeling of loss-of-function mutations to investigate mechanisms of stress resistance in cancer
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  63. Nov 2022
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    Selective advantage of epigenetically disrupted cancer cells via phenotypic inertia
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  65. Jul 2022
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    Beta-blockers disrupt mitochondrial bioenergetics and increase radiotherapy efficacy independently of beta-adrenergic receptors in medulloblastoma
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  67. Feb 2022
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    Sesquiterpene Lactones Potentiate Olaparib-Induced DNA Damage in p53 Wildtype Cancer Cells
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    The ratio of toxic-to-nontoxic microRNAs predicts platinum sensitivity in ovarian cancer
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  70. Jan 2022
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  73. Nov 2021
  74. mct.aacrjournals.org mct.aacrjournals.org
    SAGE1: a Potential Target Antigen for Lung Cancer T-Cell Immunotherapy
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    Integrated Genomic Profiling and Drug Screening of Patient-Derived Cultures Identifies Individualized Copy Number-Dependent Susceptibilities Involving PI3K Pathway and 17q Genes in Neuroblastoma
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  76. Sep 2021
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    Systematic discovery and validation of T cell targets directed against oncogenic KRAS mutations
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  78. Jun 2021
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    MicroRNA-200c restoration reveals a cytokine profile to enhance M1 macrophage polarization in breast cancer
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  80. May 2021
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    Limited inhibition of multiple nodes in a driver network blocks metastasis
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    RIPK1 activation mediates neuroinflammation and disease progression in multiple sclerosis
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