119 Matching Annotations
  1. Last 7 days
  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Intratumoral B cell and interferon signatures in newly diagnosed glioblastoma are associated with longer survival in patients treated with SurVaxM
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    pmc.ncbi.nlm.nih.gov/articles/PMC12511503/
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    CD27 agonist antibodies mediate clinical responses through intratumoral stimulation in B-cell malignancies: multicenter RiVa trial
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    pmc.ncbi.nlm.nih.gov/articles/PMC7618221/
  4. Oct 2025
  5. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Surgical and Blood-Based Minimal Residual Disease in Patients with Ovarian Cancer after First-line Therapy: Clinical Outcomes and Translational Opportunities
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    pmc.ncbi.nlm.nih.gov/articles/PMC12485385/
  6. Sep 2025
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    Intra-tumoral hypoxia promotes CD8+ T cell dysfunction via chronic activation of integrated stress response transcription factor ATF4
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    sciencedirect.com/science/article/pii/S1074761325004145
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    Identification of novel type 1 and type 2 diabetes genes by co-localization of human islet eQTL and GWAS variants with colocRedRibbon
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    sciencedirect.com/science/article/pii/S2666979X25002605
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    Parp7 generates an ADP-ribosyl degron that controls negative feedback of androgen signaling
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    pmc.ncbi.nlm.nih.gov/articles/PMC12402299/
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    An antibody-toxin conjugate targeting CD47 linked to the bacterial toxin listeriolysin O for cancer immunotherapy
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    pmc.ncbi.nlm.nih.gov/articles/PMC11952976/
  11. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Plasma exosomes from individuals with type 2 diabetes drive breast cancer aggression in patient-derived organoids
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    pmc.ncbi.nlm.nih.gov/articles/PMC12381303/
  12. Aug 2025
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    Phase 1/2 trial of encorafenib, cetuximab, and nivolumab in microsatellite stable BRAFV600E metastatic colorectal cancer
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    sciencedirect.com/science/article/pii/S153561082500340X
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    AI-driven multimodal algorithm predicts immunotherapy and targeted therapy outcomes in clear cell renal cell carcinoma
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    Reconstructed cell-type-specific rhythms in human brain link Alzheimer’s pathology, circadian stress, and ribosomal disruption
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    sciencedirect.com/science/article/pii/S0896627325005173
  16. Jul 2025
  17. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Human gut microbiome gene co-expression network reveals a loss in taxonomic and functional diversity in Parkinson’s disease
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    A developmental program of early residency promotes the differentiation of divergent uterine NK cell subsets in humans
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    biorxiv.org/content/10.1101/2025.07.05.663267v1
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    Clinical and Transcriptomic Characterization of Metastatic Hormone-Sensitive Prostate Cancer Patients with Low PTEN Expression
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  21. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Developmental pyrethroid exposure disrupts molecular pathways for MAP kinase and circadian rhythms in mouse brain
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    pmc.ncbi.nlm.nih.gov/articles/PMC12232972/
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    The costimulatory molecule ICOS limits memory-like properties and function of exhausted PD-1+CD8+ T cells
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  23. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Defining Non–small Cell Lung Cancer Tumor Microenvironment Changes at Primary and Acquired Immune Checkpoint Inhibitor Resistance Using Clinical and Real-World Data
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    pmc.ncbi.nlm.nih.gov/articles/PMC12207206/
  24. Jun 2025
  25. www.cell.com www.cell.com
    Neurodevelopmental hijacking of oligodendrocyte lineage programs drives glioblastoma infiltration
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    cell.com/developmental-cell/abstract/S1534-5807(25)00260-6
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    Transcription factor T-bet regulates the maintenance and differentiation potential of lymph node and lung effector memory B cell subsets
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    A hexamer tandem repeat RNA embedded within an SVA retrotransposon drives R-loop formation and neurodegeneration
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    sciencedirect.com/science/article/pii/S2211124725005832
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  30. May 2025
  31. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Molecular and spatial transcriptomic classification of midbrain dopamine neurons and their alterations in a LRRK2G2019S model of Parkinson’s disease
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  32. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Clear-Cell Renal Cell Carcinoma Molecular Subtypes Differ by African and European Genetic Similarity
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  33. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Heterogeneous Responses to High-Dose Testosterone in Castration-Resistant Prostate Cancer Tumors with Mixed Rb-Proficient and Rb-Deficient Cells
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    Genetic Screen in a Pre-Clinical Model of Sarcoma Development Defines Drivers and Therapeutic Vulnerabilities
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    Epigenetic silencing of DNA sensing pathway by FOXM1 blocks stress ligand-dependent antitumor immunity and immune memory
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  36. Apr 2025
  37. www.nature.com www.nature.com
    α-Ketoglutarate promotes trophectoderm induction and maturation from naive human embryonic stem cells
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    Comparative single-cell transcriptomic profiling of patient-derived renal carcinoma cells in cellular and animal models of kidney cancer
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    febs.onlinelibrary.wiley.com/doi/10.1002/2211-5463.70022
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    Clinical and Translational Results from PORTER, a Multicohort Phase I Platform Trial of Combination Immunotherapy in Metastatic Castration-Resistant Prostate Cancer
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    Global changes in Staphylococcus aureus virulence and metabolism during colonization of healthy skin
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    A common ground: an in silico assessment of the sources of intrinsic ex vivo resistance to venetoclax in acute myeloid leukemia
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    Exploring B7-H4’s Role in Prostate Cancer Dormancy after Androgen Deprivation Therapy: Extracellular Matrix Interactions and Therapeutic Opportunities
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    Phase 1/2 trial of XPO1 inhibitor selinexor plus docetaxel in previously treated, advanced KRAS mutant non-small cell lung cancer
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    aacrjournals.org/clincancerres/article/31/4/639/751730/Phase-I-II-Trial-of-Exportin-1-Inhibitor-Selinexor
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    Early Neutrophil Activation in Psoriatic Skin at Relapse Following Dead Sea Climatotherapy
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  45. Mar 2025
  46. elifesciences.org elifesciences.org
    Molecular and spatial transcriptomic classification of midbrain dopamine neurons and their alterations in a LRRK2G2019S model of Parkinson’s disease
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    elifesciences.org/reviewed-preprints/101035
  47. Feb 2025
  48. www.sciencedirect.com www.sciencedirect.com
    The endogenous antigen-specific CD8+ T cell repertoire is composed of unbiased and biased clonotypes with differential fate commitments
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    Epigenome reprogramming through H3K27 and H3K4 trimethylation as a resistance mechanism to DNA methylation inhibition in BRAFV600E-mutated colorectal cancer
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    aacrjournals.org/clincancerres/article/30/22/5166/749574/Epigenome-Reprogramming-Through-H3K27-and-H3K4
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    Platinum-based chemotherapy induces opposing effects on immunotherapy response-related spatial and stromal biomarkers in the bladder cancer microenvironment
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    Using multiomic integration to improve blood biomarkers of major depressive disorder: a case-control study
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    Myofibroblasts emerge during alveolar regeneration following influenza-virus-induced lung injury
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  54. Jan 2025
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    Steatohepatitis-induced vascular niche alterations promote melanoma metastasis
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    Cytoplasmic mRNA decay controlling inflammatory gene expression is determined by pre-mRNA fate decision
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    Aberrant Activation of Wound-Healing Programs within the Metastatic Niche Facilitates Lung Colonization by Osteosarcoma Cells
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    RECQL4 affects MHC class II‐mediated signalling and favours an immune‐evasive signature that limits response to immune checkpoint inhibitor therapy in patients with malignant melanoma
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    The Tumor Immune Microenvironment and Therapeutic Efficacy of Trastuzumab Deruxtecan in Gastric Cancer
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    JAK inhibition decreases the autoimmune burden in Down syndrome
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    Nuclear respiratory factor-1 (NRF1) induction as a powerful strategy to deter mitochondrial dysfunction and senescence in mesenchymal stem cells
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  65. Dec 2024
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    Early downmodulation of tumor glycolysis predicts response to fasting-mimicking diet in triple-negative breast cancer patients
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  68. Nov 2024
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  70. Oct 2024
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    NK Receptor Signaling Lowers TCR Activation Threshold, Enhancing Selective Recognition of Cancer Cells by TAA-Specific CTLs
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    Biomarker analyses investigating disease biology and associations with outcomes in the JAVELIN Merkel 200 trial of avelumab in metastatic Merkel cell carcinoma
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  73. Sep 2024
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    Single-cell and bulk transcriptional profiling of mouse ovaries reveals novel genes and pathways associated with DNA damage response in oocytes
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  75. May 2024
  76. www.cell.com www.cell.com
    The CD8+ T cell tolerance checkpoint triggers a distinct differentiation state defined by protein translation defects
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    Tumor niche network-defined subtypes predict immunotherapy response of esophageal squamous cell cancer
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  78. elifesciences.org elifesciences.org
    Ribosome subunit attrition and activation of the p53–MDM4 axis dominate the response of MLL-rearranged cancer cells to WDR5 WIN site inhibition
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  79. Apr 2024
  80. www.sciencedirect.com www.sciencedirect.com
    ER-associated degradation adapter Sel1L is required for CD8+ T cell function and memory formation following acute viral infection
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    Generation of human cerebral organoids with a structured outer subventricular zone
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    Developmental pyrethroid exposure disrupts molecular pathways for MAP kinase and circadian rhythms in mouse brain
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  83. Feb 2024
  84. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Single-cell and bulk transcriptional profiling of mouse ovaries reveals novel genes and pathways associated with DNA damage response in oocytes
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    Single-cell spatial transcriptomic and translatomic profiling of dopaminergic neurons in health, aging, and disease
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    sciencedirect.com/science/article/pii/S2211124724001128
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    Multi-organ single-cell RNA sequencing in mice reveals early hyperglycemia responses that converge on fibroblast dysregulation
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    faseb.onlinelibrary.wiley.com/doi/10.1096/fj.202302003R
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    Comparative transcriptomic analysis of bovine mesenchymal stromal cells reveals tissue-source and species-specific differences
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    Gestational diabetes augments group B Streptococcus infection by disrupting maternal immunity and the vaginal microbiota
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    PD-1 blockade induces reactivation of non-productive T cell responses characterized by NF-kB signaling in patients with pancreatic cancer
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  90. Jan 2024
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    Single-cell transcriptomics of the immune system in ME/CFS at baseline and following symptom provocation
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  92. Dec 2023
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    Remodeling of the human skeletal muscle proteome found after long-term endurance training but not after strength training
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  95. Nov 2023
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    Single-cell transcriptomics identifies a WNT7A-FZD5 signaling axis that maintains fallopian tube stem cells in patient-derived organoids
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    Insulin receptor loss impairs mammary tumorigenesis in mice
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  98. Oct 2023
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    Identifying genetic determinants of Streptococcus pyogenes-host interactions in a murine intact skin infection model
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    CDK19 and CDK8 Mediator kinases drive androgen-independent in vivo growth of castration-resistant prostate cancer
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    Colorectal Cancer Organoid–Stroma Biobank Allows Subtype-Specific Assessment of Individualized Therapy Responses
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  103. Sep 2023
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    Brain-region-specific changes in neurons and glia and dysregulation of dopamine signaling in Grin2a mutant mice
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  105. Aug 2023
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  108. Jul 2023
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  114. May 2023
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  118. Mar 2023
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  122. Feb 2023
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  124. Jan 2023
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  136. Oct 2022
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  138. Sep 2022
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  140. Jun 2022
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  144. May 2022
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  147. Mar 2022
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  150. Feb 2022
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  153. Nov 2021
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  155. Oct 2021
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  157. Sep 2021
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  159. Jun 2021
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