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  1. Last 7 days
  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Modeling Drug Responses and Evolutionary Dynamics using Patient-Derived Xenografts Reveals Precision Medicine Strategies for Triple Negative Breast Cancer
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    1. scibot 21 Dec 2024
      RRID:SCR_021058

      DOI: 10.1158/0008-5472.CAN-24-1703

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    pmc.ncbi.nlm.nih.gov/articles/PMC7617242/
  3. www.sciencedirect.com www.sciencedirect.com
    Early downmodulation of tumor glycolysis predicts response to fasting-mimicking diet in triple-negative breast cancer patients
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    1. scibot 18 Dec 2024
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      DOI: 10.1016/j.cmet.2024.11.004

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    sciencedirect.com/science/article/pii/S1550413124004509
  4. Nov 2024
  5. 52.53.155.43 52.53.155.43
    can-24-1703-html.html
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    1. scibot 14 Nov 2024
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  6. 52.53.155.43 52.53.155.43
    can-24-2248-html.html
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    1. scibot 08 Nov 2024
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  7. Sep 2024
  8. www.sciencedirect.com www.sciencedirect.com
    Exon Skipping-based Subtyping of Colorectal Cancers
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    1. scibot 25 Sep 2024
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      DOI: 10.1053/j.gastro.2024.08.016

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    sciencedirect.com/science/article/pii/S0016508524053575
  9. Aug 2024
  10. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Characterizing Relationships between T-cell Inflammation and Outcomes in Patients with High-Risk Neuroblastoma According to Mesenchymal and Adrenergic Signatures
    1
    1. scibot 30 Aug 2024
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      DOI: 10.1158/2767-9764.CRC-24-0214

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    ncbi.nlm.nih.gov/pmc/articles/PMC11350481/
  11. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Functional Contribution and Clinical Implication of Cancer-Associated Fibroblasts in Glioblastoma
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    1. scibot 22 Aug 2024
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      DOI: 10.1158/1078-0432.CCR-23-0493

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    ncbi.nlm.nih.gov/pmc/articles/PMC10922678/
  12. Jul 2024
  13. www.sciencedirect.com www.sciencedirect.com
    Preclinical study and phase II trial of adapting low-dose radiotherapy to immunotherapy in small cell lung cancer
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    1. scibot 19 Jul 2024
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      DOI: 10.1016/j.medj.2024.06.002

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    sciencedirect.com/science/article/pii/S2666634024002484
  14. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ALDH1A3-acetaldehyde metabolism potentiates transcriptional heterogeneity in melanoma
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    1. scibot 18 Jul 2024
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      DOI: 10.1016/j.celrep.2024.114406

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    ncbi.nlm.nih.gov/pmc/articles/PMC11290356/
  15. Jun 2024
  16. www.sciencedirect.com www.sciencedirect.com
    Nicotinamide metabolism face-off between macrophages and fibroblasts manipulates the microenvironment in gastric cancer
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    1. scibot 21 Jun 2024
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      DOI: 10.1016/j.cmet.2024.05.013

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    sciencedirect.com/science/article/pii/S155041312400189X
  17. May 2024
  18. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Modelling atopic dermatitis in healthy human skin for the characterization of topical compounds
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    1. scibot 31 May 2024
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      DOI: 10.1111/exd.15099

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    onlinelibrary.wiley.com/doi/10.1111/exd.15099
  19. aacrjournals.org aacrjournals.org
    Response rate and molecular correlates to encorafenib and binimetinib in BRAF-V600E mutant high-grade glioma
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    1. scibot 23 May 2024
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      DOI: 10.1158/1078-0432.CCR-23-3241

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    aacrjournals.org/clincancerres/article/30/10/2048/745176/Response-Rate-and-Molecular-Correlates-to
  20. www.sciencedirect.com www.sciencedirect.com
    T-bet deficiency and Hic1 induction override TGF-β-dependency in the formation of CD103+ intestine-resident memory CD8+ T cells
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    1. scibot 23 May 2024
      RRID:SCR_021058

      DOI: 10.1016/j.celrep.2024.114258

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    sciencedirect.com/science/article/pii/S2211124724005862
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    Integrative molecular and spatial analysis reveals evolutionary dynamics and tumor-immune interplay of in situ and invasive acral melanoma
    1
    1. scibot 17 May 2024
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      DOI: 10.1016/j.ccell.2024.04.012

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    sciencedirect.com/science/article/pii/S1535610824001363
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    Osr2 functions as a biomechanical checkpoint to aggravate CD8+ T cell exhaustion in tumor
    2
    1. scibot 14 May 2024
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      DOI: 10.1016/j.cell.2024.04.023

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    2. scibot 14 May 2024
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      DOI: 10.1016/j.cell.2024.04.023

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    sciencedirect.com/science/article/pii/S0092867424004483
  23. Apr 2024
  24. www.sciencedirect.com www.sciencedirect.com
    ER-associated degradation adapter Sel1L is required for CD8+ T cell function and memory formation following acute viral infection
    1
    1. scibot 30 Apr 2024
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      DOI: 10.1016/j.celrep.2024.114156

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    sciencedirect.com/science/article/pii/S2211124724004844
  25. www.sciencedirect.com www.sciencedirect.com
    Identification of hypoxic macrophages in glioblastoma with therapeutic potential for vasculature normalization
    1
    1. scibot 20 Apr 2024
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      DOI: 10.1016/j.ccell.2024.03.013

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    sciencedirect.com/science/article/pii/S1535610824001193
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    Telomere dysfunction alters intestinal stem cell dynamics to promote cancer
    1
    1. scibot 04 Apr 2024
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      DOI: 10.1016/j.devcel.2024.03.020

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    sciencedirect.com/science/article/pii/S1534580724001886
  27. Mar 2024
  28. www.nature.com www.nature.com
    Spatial transcriptomics reveals molecular dysfunction associated with cortical Lewy pathology
    1
    1. scibot 28 Mar 2024
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      DOI: 10.1038/s41467-024-47027-8

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    nature.com/articles/s41467-024-47027-8
  29. www.sciencedirect.com www.sciencedirect.com
    HIF-1α Mediates Immunosuppression and Chemoresistance in Colorectal Cancer by Inhibiting CXCL9, −10 and −11
    4
    1. scibot 15 Mar 2024
      RRID: SCR_021058

      DOI: 10.1016/j.biopha.2024.116427

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      DOI: 10.1016/j.biopha.2024.116427

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    3. scibot 15 Mar 2024
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      DOI: 10.1016/j.biopha.2024.116427

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    4. scibot 15 Mar 2024
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      DOI: 10.1016/j.biopha.2024.116427

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    sciencedirect.com/science/article/pii/S0753332224003111
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    Acetyl-CoA carboxylase obstructs CD8+ T cell lipid utilization in the tumor microenvironment
    2
    1. scibot 15 Mar 2024
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      DOI: 10.1016/j.cmet.2024.02.009

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      DOI: 10.1016/j.cmet.2024.02.009

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    sciencedirect.com/science/article/pii/S155041312400055X
  31. Feb 2024
  32. www.sciencedirect.com www.sciencedirect.com
    Spatio-molecular profiles shape the human cerebellar hierarchy along the sensorimotor-association axis
    1
    1. scibot 18 Feb 2024
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      DOI: 10.1016/j.celrep.2024.113770

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    sciencedirect.com/science/article/pii/S2211124724000986
  33. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The EstroGene database reveals diverse temporal, context-dependent, and bidirectional estrogen receptor regulomes in breast cancer
    1
    1. scibot 16 Feb 2024
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      DOI: 10.1158/0008-5472.CAN-23-0539

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    ncbi.nlm.nih.gov/pmc/articles/PMC10527051/
  34. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mutant p53 protects triple-negative breast adenocarcinomas from ferroptosis in vivo
    1
    1. scibot 15 Feb 2024
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      DOI: 10.1126/sciadv.adk1835

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    ncbi.nlm.nih.gov/pmc/articles/PMC10866549/
  35. Jan 2024
  36. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    β-catenin-driven differentiation is a tissue-specific epigenetic vulnerability in adrenal cancer
    1
    1. scibot 10 Jan 2024
      RRID:SCR_021058

      DOI: 10.1158/0008-5472.CAN-22-2712

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    ncbi.nlm.nih.gov/pmc/articles/PMC10330305/
  37. Dec 2023
  38. www.sciencedirect.com www.sciencedirect.com
    mRNA COVID-19 vaccine elicits potent adaptive immune response without the acute inflammation of SARS-CoV-2 infection
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    1. scibot 21 Dec 2023
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      DOI: 10.1016/j.isci.2023.108572

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    sciencedirect.com/science/article/pii/S2589004223026494
  39. www.sciencedirect.com www.sciencedirect.com
    Integrated multi-omics profiling to dissect the spatiotemporal evolution of metastatic hepatocellular carcinoma
    1
    1. scibot 16 Dec 2023
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      DOI: 10.1016/j.ccell.2023.11.010

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    sciencedirect.com/science/article/pii/S1535610823004014
  40. Nov 2023
  41. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cancer-prone Phenotypes and Gene Expression Heterogeneity at Single-cell Resolution in Cigarette-smoking Lungs
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    1. scibot 15 Nov 2023
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      DOI: 10.1158/2767-9764.CRC-23-0195

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    ncbi.nlm.nih.gov/pmc/articles/PMC10637260/
  42. dx.doi.org dx.doi.org
    Population-specific Mutation Patterns in Breast Tumors from African American, European American, and Kenyan Patients
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    1. scibot 10 Nov 2023
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      DOI: 10.1158/2767-9764.CRC-23-0165

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    dx.doi.org/10.1158/2767-9764.CRC-23-0165
  43. Oct 2023
  44. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Single-cell transcriptome analysis illuminating the characteristics of species-specific innate immune responses against viral infections
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      RRID:SCR_021058

      DOI: 10.1093/gigascience/giad086

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    ncbi.nlm.nih.gov/pmc/articles/PMC10580374/
  45. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Colorectal Cancer Organoid–Stroma Biobank Allows Subtype-Specific Assessment of Individualized Therapy Responses
    1
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      DOI: 10.1158/2159-8290.CD-23-0050

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    ncbi.nlm.nih.gov/pmc/articles/PMC10551667/
  46. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Comprehensive Analysis of Tumor Microenvironment Reveals Prognostic ceRNA Network Related to Immune Infiltration in Sarcoma
    1
    1. scibot 06 Oct 2023
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      DOI: 10.1158/1078-0432.CCR-22-3396

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    ncbi.nlm.nih.gov/pmc/articles/PMC10543973/
  47. Aug 2023
  48. dx.doi.org dx.doi.org
    Integrative single-cell and bulk transcriptomes analyses identify intrinsic HNSCC subtypes with distinct prognoses and therapeutic vulnerabilities
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    1. scibot 04 Aug 2023
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      DOI: 10.1158/1078-0432.CCR-22-3563

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    2. scibot 04 Aug 2023
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      DOI: 10.1158/1078-0432.CCR-22-3563

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    dx.doi.org/10.1158/1078-0432.CCR-22-3563
  49. Jul 2023
  50. www.sciencedirect.com www.sciencedirect.com
    Temporal transcriptome features identify early skeletal commitment during human epiphysis development at single-cell resolution
    1
    1. scibot 29 Jul 2023
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      DOI: 10.1016/j.isci.2023.107200

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    sciencedirect.com/science/article/pii/S2589004223012774
  51. www.sciencedirect.com www.sciencedirect.com
    Derivation of CD8+ T-cell Infiltration Potentiators in Non-Small Cell Lung Cancer Through Tumor Microenvironment Analysis
    1
    1. scibot 11 Jul 2023
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      DOI: 10.1016/j.isci.2023.107095

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    sciencedirect.com/science/article/pii/S2589004223011720
  52. Jun 2023
  53. 52.53.155.43 52.53.155.43
    can-22-2712-html.html
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    1. scibot 29 Jun 2023
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      DOI: 10.1158/0008-5472.can-22-2712

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    52.53.155.43/726555d37fadfa1ef429cf94df3437d3f13c8b94/can-22-2712-html.html
  54. www.sciencedirect.com www.sciencedirect.com
    Microsatellite instability states serve as predictive biomarkers for tumors chemotherapy sensitivity
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    1. scibot 23 Jun 2023
      RRID:SCR_021058

      DOI: 10.1016/j.isci.2023.107045

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  55. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genomic and Transcriptomic Analysis of Relapsed and Refractory Childhood Solid Tumors Reveals a Diverse Molecular Landscape and Mechanisms of Immune Evasion
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    1. scibot 08 Jun 2023
      RRID:SCR_021058

      DOI: 10.1158/0008-5472.CAN-21-1033

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  56. May 2023
  57. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Comparative Tumor Microenvironment Analysis of Primary and Recurrent Ovarian Granulosa Cell Tumors
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      RRID:SCR_021058

      DOI: 10.1158/1541-7786.MCR-22-0623

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    ncbi.nlm.nih.gov/pmc/articles/PMC10150241/
  58. Apr 2023
  59. aacrjournals.org aacrjournals.org
    Multi-substrate metabolic tracing reveals marked heterogeneity and dependency on fatty acid metabolism in human prostate cancer
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    1. scibot 21 Apr 2023
      RRID:SCR_021058

      DOI: 10.1158/1541-7786.MCR-22-0796

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    aacrjournals.org/mcr/article/21/4/359/718952/Multi-substrate-Metabolic-Tracing-Reveals-Marked
  60. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Induction of PARP7 Creates a Vulnerability for Growth Inhibition by RBN2397 in Prostate Cancer Cells
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    1. scibot 20 Apr 2023
      RRID:SCR_021058

      DOI: 10.1158/2767-9764.CRC-23-0086

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  61. Mar 2023
  62. link.springer.com link.springer.com
    Expression of down-regulated ERV LTR elements associates with immune activation in human small-cell lung cancers
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    1. scibot 15 Mar 2023
      RRID:SCR_021058

      DOI: 10.1186/s13100-023-00290-w

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  63. Feb 2023
  64. aacrjournals.org aacrjournals.org
    Plk1 Inhibitors and Abiraterone Synergistically Disrupt Mitosis and Kill Cancer Cells of Disparate Origin Independently of Androgen Receptor Signaling
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      RRID:SCR_021058

      DOI: 10.1158/0008-5472.CAN-22-1533

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    aacrjournals.org/cancerres/article/83/2/219/715076/Plk1-Inhibitors-and-Abiraterone-Synergistically
  65. Nov 2022
  66. www.sciencedirect.com www.sciencedirect.com
    Systematic single-cell pathway analysis to characterize early T cell activation
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    1. scibot 23 Nov 2022
      RRID:SCR_021058

      DOI: 10.1016/j.celrep.2022.111697

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  67. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Alternative splicing downstream of EMT enhances phenotypic plasticity and malignant behavior in colon cancer
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    1. scibot 22 Nov 2022
      RRID:SCR_021058

      DOI: 10.7554/eLife.82006

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  68. www.sciencedirect.com www.sciencedirect.com
    CD8+ T cell metabolic rewiring defined by scRNA-seq identifies a critical role of ASNS expression dynamics in T cell differentiation
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    1. scibot 16 Nov 2022
      RRID:SCR_021058

      DOI: 10.1016/j.celrep.2022.111639

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  69. www.sciencedirect.com www.sciencedirect.com
    Tumor-intrinsic SIRPA promotes sensitivity to checkpoint inhibition immunotherapy in melanoma
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      RRID:SCR_021058

      DOI: 10.1016/j.ccell.2022.10.012

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  70. Oct 2022
  71. www.sciencedirect.com www.sciencedirect.com
    Circadian transcriptional pathway atlas highlights a proteasome switch in intermittent fasting
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      RRID:SCR_021058

      DOI: 10.1016/j.celrep.2022.111547

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    sciencedirect.com/science/article/pii/S2211124722014036
  72. Sep 2022
  73. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Biological misinterpretation of transcriptional signatures in tumor samples can unknowingly undermine mechanistic understanding and faithful alignment with preclinical data
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      RRID:SCR_021058

      DOI: 10.1158/1078-0432.CCR-22-1102

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    A small proportion of X-linked genes contribute to X chromosome upregulation in early embryos via BRD4-mediated transcriptional activation
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      RRID:SCR_021058

      DOI: 10.1016/j.cub.2022.08.059

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    sciencedirect.com/science/article/pii/S0960982222013811
  75. Jul 2022
  76. link.springer.com link.springer.com
    Prediction of cellular targets in diabetic kidney diseases with single-cell transcriptomic analysis of db/db mouse kidneys
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      RRID:SCR_021058

      DOI: 10.1007/s12079-022-00685-z

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    link.springer.com/article/10.1007/s12079-022-00685-z
  77. Jan 2022
  78. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Altered temporal sequence of transcriptional regulators in the generation of human cerebellar granule cells
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    1. scibot 05 Jan 2022
      RRID:SCR_021058

      DOI: 10.7554/eLife.67074

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    ncbi.nlm.nih.gov/pmc/articles/PMC8687658/
  79. Nov 2021
  80. www.sciencedirect.com www.sciencedirect.com
    Multi-tumor analysis of cancer-stroma interactomes of patient-derived xenografts unveils the unique homeostatic process in renal cell carcinomas
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      RRID:SCR_021058

      DOI: 10.1016/j.isci.2021.103322

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    sciencedirect.com/science/article/pii/S2589004221012918
  81. Aug 2021
  82. www.sciencedirect.com www.sciencedirect.com
    Uncoupling of gene expression from copy number presents therapeutic opportunities in aneuploid cancers
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    1. scibot 05 Aug 2021
      RRID:SCR_021058

      DOI: 10.1016/j.xcrm.2021.100349

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    sciencedirect.com/science/article/pii/S2666379121001981
  83. Jul 2021
  84. www.sciencedirect.com www.sciencedirect.com
    Specialized endothelial tip cells guide neuroretina vascularization and blood-retina-barrier formation
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    1. scibot 17 Jul 2021
      RRID:SCR_021058

      DOI: 10.1016/j.devcel.2021.06.021

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    sciencedirect.com/science/article/pii/S1534580721005281
  85. May 2021
  86. www.sciencedirect.com www.sciencedirect.com
    Stem-like cells drive NF1-associated MPNST functional heterogeneity and tumor progression
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    1. scibot 19 May 2021
      RRID:SCR_021058

      DOI: 10.1016/j.stem.2021.04.029

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    sciencedirect.com/science/article/pii/S1934590921001879