110 Matching Annotations
  1. Last 7 days
  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Immune dysregulation and exhaustion in EBV- associated hemophagocytic lymphohistiocytosis: insights from single-cell transcriptomics and TCR repertoire analysis
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    pmc.ncbi.nlm.nih.gov/articles/PMC13485814/
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    Short-term gonadal cultures are sufficient for germline transmission in a songbird
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    sciencedirect.com/science/article/pii/S2213671126002638
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    An IL-34–IGF-1 inflammatory axis fuels KRAS-mutant lung cancer progression
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    biorxiv.org/content/10.64898/2026.07.14.738492v1
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    Brain perivascular macrophages regulate endothelial cell function via a cMAF-dependent transcriptional program in mouse and human
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    sciencedirect.com/science/article/pii/S0092867426008755
  6. Aug 2026
  7. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Splenic macrophage-B cell axis drives systemic autoimmune-like pathology in Cerebral Malaria
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    pmc.ncbi.nlm.nih.gov/articles/PMC13454142/
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    HER2 heterogeneous breast cancer models reveal novel therapeutic targets and subclonal dynamics during evolution to resistance to HER2-targeted therapies
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    pmc.ncbi.nlm.nih.gov/articles/PMC13430225/
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    Temporal Genomic Analysis of Homogeneous Tumor Models Reveals Key Regulators of Immune Evasion in Melanoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC11873729/
  10. Jul 2026
  11. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A Phase 2 Study of Stereotactic Ablative Radiotherapy Plus Atezolizumab Plus Tiragolumab in Treatment-naïve Patients with Advanced Non-small Cell Lung Cancer
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    ATM Deficiency Induces TGFβ-Mediated Stromal Programming in Pancreatic Cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC13370118/
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    Single-Cell and Spatial Analysis Reveal the Differences Between Left-Sided and Right-Sided Colorectal Cancer
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    onlinelibrary.wiley.com/doi/10.1111/cpr.70260
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    Survival Genie 2: a next-generation web server for targeted and single-cell-based survival analyses
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    pmc.ncbi.nlm.nih.gov/articles/PMC13343920/
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    USP20-Driven Cholesterol Metabolism Links Inflammatory Signaling to Malignancy and Stromal Co-evolution in Pancreatic Cancer
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    aacrjournals.org/cancerres/article/86/3/712/771921/USP20-Driven-Cholesterol-Metabolism-Links
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    Single-Cell and Spatial Transcriptomic Profiling Reveals Epithelial Functional States and Fibroblast Phenotypes in Hormone Therapy–Naïve Localized Prostate Cancer
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    aacrjournals.org/cancerres/article/86/8/1836/782625/Single-Cell-and-Spatial-Transcriptomic-Profiling
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    Integrative bulk and single-cell analyses implicate ASL in MIF-associated myeloid programs in glioblastoma
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    Combined angiogenic and hypertrophic gene therapy enhances skeletal muscle growth | American Journal of Physiology-Cell Physiology | American Physiological Society
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    AXIN1 and AXIN2 regulate the WNT-signaling landscape to promote distinct mesoderm programs
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  20. www.biorxiv.org www.biorxiv.org
    Single-nucleus Transcriptomics Reveals Precystic Dysfunction in Polycystic Kidney Disease
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    biorxiv.org/content/10.64898/2026.06.23.730438v1
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    The mitochondrial unfolded protein response in human microglia disrupts neuronal–glial communication and promotes senescence
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    nature.com/articles/s41593-026-02320-1
  22. Jun 2026
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    Phase II Trial of Ixazomib Combined with Gemcitabine and Doxorubicin in Patients with SMARCB1-Deficient Renal Medullary Carcinoma
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    aacrjournals.org/clincancerres/article/32/10/1946/785097/Phase-II-Trial-of-Ixazomib-Combined-with
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    Efficacy and Safety of Tunlametinib in Adults with Inoperable Neurofibromatosis Type 1-Associated Plexiform Neurofibromas: Phase IIa Trial and Biomarker Research
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    Single-cell RNA profiling of oligodendroglial lineage cells derived from iPSCs carrying Parkinson’s disease-relevant LRRK2-G2019S mutation
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    CCL3+ neutrophil signature predicts response to neoadjuvant toripalimab plus chemotherapy in patients with hypopharyngeal squamous cell carcinoma: A phase II trial
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  27. May 2026
  28. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Spatial Transcriptomics Reveals Location-Specific Tumor Cell Subtypes and Signaling within Multifocal Small Intestinal Neuroendocrine Tumors
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  29. faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com
    Bulk Sequencing Combined With Single-Cell Sequencing Identifies High Expression of VCAN in Fibroblasts Promoting the Progression of High-Stemness Gastric Adenocarcinoma Cells
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  30. www-cell-com.eproxy.lib.hku.hk www-cell-com.eproxy.lib.hku.hk
    Whole-genome doubling drives immune evasion by silencing antigen presentation
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    www-cell-com.eproxy.lib.hku.hk/cancer-cell/fulltext/S1535-6108(26)00218-7
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    Functionally characterizing the renal cell carcinoma tumor immune microenvironment via patient-derived ex vivo models
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  32. Apr 2026
  33. www.biorxiv.org www.biorxiv.org
    Midkine Dependency Defines a Therapeutically Actionable Vulnerability in Medulloblastoma
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    biorxiv.org/content/10.64898/2026.04.11.717918v1
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    Combined inhibition of S100A4 and TIGIT suppresses late-stage breast cancer metastasis
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  35. Mar 2026
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    Chemoradiation Reprograms Tumor Cells and the Immune Microenvironment in Cervical Cancer
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  38. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A highly resolved integrated single-cell atlas of HPV-negative head and neck cancer
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    The ubiquitin–proteasome system is an important driver of EBV-associated nasopharyngeal carcinoma progression: a meta-analysis of transcriptomic data
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    LIFUS-driven engineered bacteria reprogram immunosuppressive niches via mechano-NOTCH signaling
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  41. Feb 2026
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    Pan-cancer single-cell RNA sequencing analysis refines multi-origin monocyte and macrophage lineages
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    Inhibition of focal adhesion kinase impairs tumor formation and preserves hearing in a murine model of NF2-related schwannomatosis
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    Inhibition of focal adhesion kinase impairs tumor formation and preserves hearing in a murine model of NF2-related schwannomatosis
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    Single-dose psilocybin promotes cell-type-specific changes of neurons in the orbitofrontal cortex
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  46. Jan 2026
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    IGSF11-VISTA is a critical and targetable immune checkpoint axis in diffuse midline glioma
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    Rhinovirus triggers distinct host responses through differential engagement of epithelial innate immune signaling
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    Spatial transcriptomics of the developing mouse brain immune landscape reveals effects of maternal immune activation and microbiome depletion
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    SLC39A10 drives M2 macrophage polarization and gastric cancer progression through the MAPK14(p38α) pathway
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    Protocol to evaluate mouse brain spatial cell type-resolved transcriptomic discoveries using 10× Visium spatial transcriptomics and FLEX scRNA-seq
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  52. Dec 2025
  53. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    CD146+CAFs mediate immunosuppression in gastric cancer via COL4A1: potential therapeutic targets
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  54. Nov 2025
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    SOCS1 Protects Acute Myeloid Leukemia against Allogeneic T Cell–Mediated Cytotoxicity
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    Trilaciclib triggers a neutrophil-related immune response and sensitizes non-small cell lung cancer to anti-PD-1 therapy
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  58. Oct 2025
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  60. Sep 2025
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    Spatially patterned kidney assembloids recapitulate progenitor self-assembly and enable high-fidelity in vivo disease modeling
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  62. www.biorxiv.org www.biorxiv.org
    The Ubiquitin–Proteasome System is an Important Driver of EBV-Associated Nasopharyngeal Carcinoma Progression: A Meta-Analysis of Transcriptomics Data
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    Spatial colocalization and molecular crosstalk of myofibroblastic CAFs and tumor cells shape lymph node metastasis in oral squamous cell carcinoma
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    An antibody-toxin conjugate targeting CD47 linked to the bacterial toxin listeriolysin O for cancer immunotherapy
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    Plasma exosomes from individuals with type 2 diabetes drive breast cancer aggression in patient-derived organoids
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    An HIV fusion-inhibitory lipopeptide provides robust post-exposure prophylaxis and prevents viral reservoir seeding in macaques
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  67. Jul 2025
  68. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
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    Dissecting FAP+ Cell Diversity in Pancreatic Cancer Uncovers an Interferon-Response Subtype of Cancer-Associated Fibroblasts with Tumor-Restraining Properties
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  70. Jun 2025
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    Spatial–Temporal Diversity of Extrachromosomal DNA Shapes Urothelial Carcinoma Evolution and the Tumor Immune Microenvironment
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    Adventitial fibroblasts direct smooth muscle cell-state transition in pulmonary vascular disease
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    Distinct molecular patterns in R6/2 HD mouse brain: Insights from spatiotemporal transcriptomics
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  74. May 2025
  75. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Intratumoral Fusobacterium nucleatum Recruits Tumor-Associated Neutrophils to Promote Gastric Cancer Progression and Immune Evasion
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    Epigenetic silencing of DNA sensing pathway by FOXM1 blocks stress ligand-dependent antitumor immunity and immune memory
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    Inhibition of autotaxin activity with IOA-289 decreases fibrosis in mouse E0771 breast tumors
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  78. Mar 2025
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    Comparative Single-Cell Transcriptomics of Human Neuroblastoma and Preclinical Models Reveals Conservation of an Adrenergic Cell State
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  81. Feb 2025
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    Individualized patient tumor organoids faithfully preserve human brain tumor ecosystems and predict patient response to therapy
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    Myofibroblasts emerge during alveolar regeneration following influenza-virus-induced lung injury
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  85. Jan 2025
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    Spatial transcriptomic analysis identifies epithelium-macrophage crosstalk in endometriotic lesions
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    Neonatal Brain Injury Triggers Niche-Specific Changes to Cellular Biogeography
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    Phenotypic plasticity and increased infiltration of peripheral blood-derived TREM1+ mono-macrophages following radiotherapy in rectal cancer
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  89. Dec 2024
  90. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Exploring the Role of Ccn3 in Type III Cell of Mice Taste Buds
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    Microglial lipid phosphatase SHIP1 limits complement-mediated synaptic pruning in the healthy developing hippocampus
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  92. www.biorxiv.org www.biorxiv.org
    Combined inhibition of S100A4 and TIGIT suppresses late-stage breast cancer metastasis to the lung by activating T and NK cells
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    biorxiv.org/content/10.1101/2024.11.24.624743v1
  93. Nov 2024
  94. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Spatial Multiomics Reveals Intratumoral Immune Heterogeneity with Distinct Cytokine Networks in Lung Cancer Brain Metastases
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  95. www.mdpi.com www.mdpi.com
    NF-ΚB Activation as a Key Driver in Chronic Lymphocytic Leukemia Evolution to Richter’s Syndrome: Unraveling the Influence of Immune Microenvironment Dynamics
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  96. Sep 2024
  97. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Reconstitution of the Multiple Myeloma Microenvironment Following Lymphodepletion with BCMA CAR-T Therapy
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  98. Aug 2024
  99. www.cell.com www.cell.com
    Single-cell dissection of the human blood-brain barrier and glioma blood-tumor barrier
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    Functional Contribution and Clinical Implication of Cancer-Associated Fibroblasts in Glioblastoma
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  101. Jul 2024
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    Timing of whole genome duplication is associated with tumor-specific MHC-II depletion in serous ovarian cancer
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  103. Jun 2024
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    Nicotinamide metabolism face-off between macrophages and fibroblasts manipulates the microenvironment in gastric cancer
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  105. May 2024
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    Integrative molecular and spatial analysis reveals evolutionary dynamics and tumor-immune interplay of in situ and invasive acral melanoma
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  141. Dec 2022
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