94 Matching Annotations
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    Mucosal-associated invariant T cells recognize a tumor-derived metabolite in the DNA synthesis pathway
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    pmc.ncbi.nlm.nih.gov/articles/PMC13342176/
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    Induction of human pruriceptors from pluripotent stem cells via transcription factors
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    sciencedirect.com/science/article/pii/S2213671126002158
  4. Jun 2026
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    PRECISE: A prognostic thyrocyte-derived gene signature for papillary thyroid carcinoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC13264843/
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    Temporal control of sgRNA library activation unlocks large-scale in vivo CRISPR screens
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    sciencedirect.com/science/article/pii/S2667237526001700
  7. May 2026
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    Maternal-fetal type I interferon signaling drives TREM2 dysregulation and synaptic dysfunction in neurodevelopmental disorders
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    sciencedirect.com/science/article/pii/S0896627326003387
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    Dietary soy shapes the microbiome to induce commensal-specific T follicular helper cells and IgA production
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    sciencedirect.com/science/article/pii/S1074761326001755
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    A regulatory circuitry driving a noradrenergic to mesenchymal transition highlights YAP/TAZ as critical players in neuroblastoma plasticity
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    sciencedirect.com/science/article/pii/S2211124726004298
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    Identification of a distinct cluster of LY6E+ macrophages in esophageal squamous cell carcinoma: functional phenotype, spatial interaction, and prognostic significance
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    nature.com/articles/s41416-026-03456-4
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    Whole-genome doubling drives immune evasion by silencing antigen presentation
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    www-cell-com.eproxy.lib.hku.hk/cancer-cell/fulltext/S1535-6108(26)00218-7
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    Dendritic cell redundancy enables priming of anti-tumor CD4+ T cells in pancreatic cancer
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    Cohesin complex cooperates with PU.1 at super-enhancers to regulate the differentiation and identity of conventional dendritic cells
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    Integrated Single-Cell Whole-Genome Sequencing and Spatial Transcriptomics Reveal Intratumoral Heterogeneity in Ovarian Cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC13137417/
  16. Apr 2026
  17. aacrjournals.org aacrjournals.org
    Tumor and Immune Dynamics Following Sequential CDK4/6 and PD-1 Inhibition: Results from a Phase 2 Study in Dedifferentiated Liposarcoma
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    aacrjournals.org/cancerrescommun/article/6/2/437/774902/Tumor-and-Immune-Dynamics-Following-Sequential
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    Somatic cancer variants enriched in Alzheimer’s disease microglia-like cells drive inflammatory and proliferative states
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    sciencedirect.com/science/article/pii/S0092867426003417
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    Activation of T cell-intrinsic p53 by acetylation elicits antitumor immunity to boost cancer immunotherapy
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    aacrjournals.org/cancerdiscovery/article/16/1/155/771238/Activation-of-T-Cell-Intrinsic-p53-by-Acetylation
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    Patient-derived pediatric brain tumor orthotopic xenografts and tumor organoids faithfully recapitulate primary tumors
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    science.org/doi/10.1126/sciadv.aea4966
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    Organ injury in systemic autoimmunity is mediated by stem-like CD8+ T cells arising from tissue-draining lymph nodes
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    Stem cell control in the lung by an autocrine injury-activated Igf complex
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    Decoding B-cell Signatures of Complete Pathologic Response to Perioperative Chemoimmunotherapy in Non–Small Cell Lung Cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC13080320/
  24. 54.241.53.176 54.241.53.176
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    Targeting TPX2-dependent lineage plasticity by CDK4/6 inhibition reverses therapy resistance in neuroendocrine bladder carcinoma
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  27. Mar 2026
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    Perinatal infection elicits clonally restricted T follicular helper cell responses that drive antibody-mediated viral control
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    Composition and functional state of T and NK cells in the extramedullary myeloma tumor microenvironment
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    Gene regulatory network determinants of rapid recall in human memory CD4+ T cells
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  31. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A Multi-Step Immune-Competent Genetically Engineered Mouse Model Reveals Phenotypic Plasticity in Uveal Melanoma
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  32. Feb 2026
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    MafB is a conserved transcriptional regulator of macrophage development and functional identity across tissues and species
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    Analysis of cranial tenocyte heterogeneity reveals a role for Wnt signaling in tendon attachments
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  35. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Genotype-to-phenotype mapping of somatic clonal mosaicism via single-cell co-capture of DNA mutations and mRNA transcripts
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    Single-dose psilocybin promotes cell-type-specific changes of neurons in the orbitofrontal cortex
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  37. Jan 2026
  38. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Timing genomic antigen loss in multiple myeloma treated with T-cell redirecting immunotherapies
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  39. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Biosafety assessment of engineered CCL20 locked dimers in vivo
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  40. Dec 2025
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    Modeling human embryo implantation in vitro
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    Stc1-expressing myofibroblasts are a developmentally distinct lineage cleared through apoptosis in the neonatal lung
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    Olaparib and radiotherapy induce type I interferon and CD8+ T cell-dependent sensitization to immunotherapy in pancreatic cancer
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  45. Nov 2025
  46. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Circulating neoantigen- and viral oncoprotein–specific CD8+ T cells share a transcriptional signature
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  47. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Tissue-specific immunosuppressive and proliferating macrophages fuel early metastatic progression of human colorectal cancer to liver
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    Companion cells with high florigen production express other small proteins and reveal a nitrogen-sensitive FT repressor
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    In vivo differentiation of embryonic cells devoid of key reprogramming factors
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  50. Oct 2025
  51. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Single Cell Analyses Reveal a Functionally Heterogeneous Exhausted CD8+ T Cell Subpopulation that is Correlated with Response to Checkpoint Therapy in Melanoma
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  52. Sep 2025
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    Survivin promotes stem cell competence for skin cancer initiation
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    A framework to mine laser microdissection-based omics data and uncover regulators of pancreatic cancer heterogeneity
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    An HIV fusion-inhibitory lipopeptide provides robust post-exposure prophylaxis and prevents viral reservoir seeding in macaques
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    Hyperandrogenism in polycystic ovary syndrome augments Estrogen synthesis through AR-FOXL2–mediated activation of the aromatase gene in granulosa cells
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  57. Aug 2025
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    Characteristics of a CCL21 gene-modified dendritic cell vaccine utilized for a clinical trial in non-small cell lung cancer
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  60. Jul 2025
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    Cellular crosstalk mediated by TGF-β drives epithelial-mesenchymal transition in patient-derived multi-compartment biliary organoids
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    TET2-mutant myeloid cells mitigate Alzheimer’s disease progression via CNS infiltration and enhanced phagocytosis in mice
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  64. Jun 2025
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    ChemPerturb-seq screen identifies a small molecule cocktail enhancing human beta cell survival after subcutaneous transplantation
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    Combining Apatinib and Oxaliplatin Remodels the Immunosuppressive Tumor Microenvironment and Sensitizes Desert-Type Gastric Cancer to Immunotherapy
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  67. May 2025
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    hiPSC-neurons recapitulate the subtype-specific cell intrinsic nature of susceptibility to neurodegenerative disease-relevant aggregation
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    Heterogeneous Responses to High-Dose Testosterone in Castration-Resistant Prostate Cancer Tumors with Mixed Rb-Proficient and Rb-Deficient Cells
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    Integrating collecting systems in human kidney organoids through fusion of distal nephron to ureteric bud
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  72. Apr 2025
  73. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Cellular evolution of the hypothalamic preoptic area of behaviorally divergent deer mice
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    Stratification of enterochromaffin cells by single-cell expression analysis
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    CD103+CD56+ ILCs Are Associated with an Altered CD8+ T-cell Profile within the Tumor Microenvironment
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    Targeting the dendritic cell-secreted immunoregulatory cytokine CCL22 alleviates radioresistance
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  77. Feb 2025
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    Individualized patient tumor organoids faithfully preserve human brain tumor ecosystems and predict patient response to therapy
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  79. Jan 2025
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    CRISPRi-based screens in iAssembloids to elucidate neuron-glia interactions
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  81. Dec 2024
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    Expanding GABAergic Neuronal Diversity in iPSC-Derived Disease Models
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    Cell therapy with human IL-10-producing ILC2s limits xenogeneic graft-versus-host disease by inhibiting pathogenic T cell responses
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    Single-cell transcriptomics of vomeronasal neuroepithelium reveals a differential endoplasmic reticulum environment amongst neuronal subtypes
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    elifesciences.org/articles/98250
  85. www.science.org www.science.org
    CD4+ T cells with convergent TCR recombination reprogram stroma and halt tumor progression in adoptive therapy
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    science.org/doi/10.1126/sciimmunol.adp6529
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    Early downmodulation of tumor glycolysis predicts response to fasting-mimicking diet in triple-negative breast cancer patients
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  87. Nov 2024
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    Genetic requirement of dact1/2 to regulate noncanonical Wnt signaling and calpain 8 during embryonic convergent extension and craniofacial morphogenesis
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    CD4+ T cells with convergent TCR recombination reprogram stroma and halt tumor progression in adoptive therapy
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  90. Sep 2024
  91. elifesciences.org elifesciences.org
    Muscle-resident mesenchymal progenitors sense and repair peripheral nerve injury via the GDNF-BDNF axis
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    Targeting EGLN2/PHD1 protects motor neurons and normalizes the astrocytic interferon response
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  93. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Blockade of IL1β and PD1 with Combination Chemotherapy Reduces Systemic Myeloid Suppression in Metastatic Pancreatic Cancer with Heterogeneous Effects in the Tumor
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  94. Aug 2024
  95. www.cell.com www.cell.com
    Schwann cell-secreted PGE2 promotes sensory neuron excitability during development
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  96. Jul 2024
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    Integrated transcriptomics of human blood vessels defines a spatially controlled niche for early mesenchymal progenitor cells
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  98. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Timing of whole genome duplication is associated with tumor-specific MHC-II depletion in serous ovarian cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC11258338/
  99. May 2024
  100. www.sciencedirect.com www.sciencedirect.com
    Osr2 functions as a biomechanical checkpoint to aggravate CD8+ T cell exhaustion in tumor
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  101. www.biorxiv.org www.biorxiv.org
    Psilocybin Promotes Cell-Type-Specific Changes in the Orbitofrontal Cortex Revealed by Single-Nucleus RNA-seq
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    biorxiv.org/content/10.1101/2024.01.07.573163v1
  102. Apr 2024
  103. www.sciencedirect.com www.sciencedirect.com
    Generation of human cerebral organoids with a structured outer subventricular zone
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  104. Feb 2024
  105. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mutant p53 protects triple-negative breast adenocarcinomas from ferroptosis in vivo
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  106. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Comparative transcriptomic analysis of bovine mesenchymal stromal cells reveals tissue-source and species-specific differences
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    ncbi.nlm.nih.gov/pmc/articles/PMC10838956/
  107. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PD-1 blockade induces reactivation of non-productive T cell responses characterized by NF-kB signaling in patients with pancreatic cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC10831338/
  108. Jan 2024
  109. www.sciencedirect.com:5037 www.sciencedirect.com:5037
    An exhausted-like microglial population accumulates in aged and APOE4 genotype Alzheimer’s brains
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    Trem2 expression in microglia is required to maintain normal neuronal bioenergetics during development
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    sciencedirect.com/science/article/pii/S1074761323005332
  111. Dec 2023
  112. 52.53.155.43 52.53.155.43
    ccr-23-1444-html.html
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  113. Oct 2023
  114. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Single-cell transcriptome analysis illuminating the characteristics of species-specific innate immune responses against viral infections
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    ncbi.nlm.nih.gov/pmc/articles/PMC10580374/
  115. 52.53.155.43 52.53.155.43
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  116. Sep 2023
  117. www.sciencedirect.com www.sciencedirect.com
    Single-cell profiling of murine bladder cancer identifies sex-specific transcriptional signatures with prognostic relevance
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    sciencedirect.com/science/article/pii/S2589004223017807
  118. Aug 2023
  119. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Comparative single-cell profiling reveals distinct cardiac resident macrophages essential for zebrafish heart regeneration
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    ncbi.nlm.nih.gov/pmc/articles/PMC10411971/
  120. May 2023
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    Glioblastoma cell fate is differentially regulated by the microenvironments of the tumor bulk and infiltrative margin
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    sciencedirect.com/science/article/pii/S2211124723004837
  122. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CHD-associated enhancers shape human cardiomyocyte lineage commitment
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    ncbi.nlm.nih.gov/pmc/articles/PMC10156167/
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    Age-dependent immune and lymphatic responses after spinal cord injury
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    sciencedirect.com/science/article/pii/S0896627323002969
  124. Mar 2023
  125. europepmc.org europepmc.org
    Jarid2 promotes temporal progression of retinal progenitors via repression of Foxp1
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    europepmc.org/article/med/36924502
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    IFNγ is a central node of cancer immune equilibrium
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    sciencedirect.com/science/article/pii/S2211124723002309