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Mar 2026
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Cyrene: a novel geroprotective compound that extends lifespan and healthspan in C. elegans and Drosophila

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1. scibot 23 Mar 2026
  
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  CF1038
  
  DOI: 10.1038/s41514-025-00309-x
  
  Resource: (WB Cat# WBStrain00004840,RRID:WB-STRAIN:WBStrain00004840)
  
  Curator: @olekpark
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12819529/
Dec 2025
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Cyrene: A Novel Geroprotective Compound that Extends Lifespan and Healthspan in C. elegans and Drosophila

1
1. scibot 03 Dec 2025
  
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  CF1038
  
  DOI: 10.1101/2025.08.01.668202
  
  Resource: (WB Cat# WBStrain00004840,RRID:WB-STRAIN:WBStrain00004840)
  
  Curator: @Apiekniewska
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12324423/
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Computer prediction and genetic analysis identifies retinoic acid modulation as a driver of conserved longevity pathways in genetically-diverse Caenorhabditis nematodes

1
1. scibot 02 Dec 2025
  
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  CF1038
  
  DOI: 10.1101/2024.10.23.619838
  
  Resource: (WB Cat# WBStrain00004840,RRID:WB-STRAIN:WBStrain00004840)
  
  Curator: @Apiekniewska
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12258912/
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Excretory gland cell and NSPC genes in C. elegans: investigating their physiological roles

1
1. scibot 02 Dec 2025
  
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  Supplementary File 1
  
  DOI: 10.1093/genetics/iyaf125
  
  Resource: (WB Cat# WBStrain00004840,RRID:WB-STRAIN:WBStrain00004840)
  
  Curator: @Apiekniewska
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12406010/
Nov 2025
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Environmental NaCl affects C. elegans development and aging

1
1. scibot 22 Nov 2025
  
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  Supplement 1
  
  DOI: 10.1101/2025.03.09.641258
  
  Resource: (WB Cat# WBStrain00004840,RRID:WB-STRAIN:WBStrain00004840)
  
  Curator: @Apiekniewska
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11952357/
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CaMK modulates sensory neural activity to control longevity and proteostasis

1
1. scibot 22 Nov 2025
  
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  Appendix 01
  
  DOI: 10.1073/pnas.2423428122
  
  Resource: (WB Cat# WBStrain00004840,RRID:WB-STRAIN:WBStrain00004840)
  
  Curator: @Apiekniewska
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12107105/
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Thiostrepton induces apoptotic cell death at the level of BCL-2/CED-9 in C. elegans

1
1. scibot 22 Nov 2025
  
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  CF1038
  
  DOI: 10.1038/s41598-025-09446-5
  
  Resource: (WB Cat# WBStrain00004840,RRID:WB-STRAIN:WBStrain00004840)
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12238647/
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Pathogen infection induces sickness behaviors through neuromodulators linked to stress and satiety in C. elegans

1
1. scibot 22 Nov 2025
  
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  Supplementary Information
  
  DOI: 10.1038/s41467-025-58478-y
  
  Resource: (WB Cat# WBStrain00004840,RRID:WB-STRAIN:WBStrain00004840)
  
  Curator: @Apiekniewska
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11968842/
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Intestinal RICT-1 regulates the larval germline progenitor pool via the vitellogenin VIT-3 in C. elegans

1
1. scibot 21 Nov 2025
  
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  Supplement 1
  
  DOI: 10.1101/2025.01.08.632040
  
  Resource: (WB Cat# WBStrain00004840,RRID:WB-STRAIN:WBStrain00004840)
  
  Curator: @Apiekniewska
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11741266/
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Neuronal CBP-1 is Required for Enhanced Body Muscle Proteostasis in Response to Reduced Translation Downstream of mTOR

1
1. scibot 20 Nov 2025
  
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  CF1038
  
  DOI: 10.31083/j.fbl2907264
  
  Resource: (WB Cat# WBStrain00004840,RRID:WB-STRAIN:WBStrain00004840)
  
  Curator: @Apiekniewska
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11412575/
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SHC-3: a previously unidentified C. elegans Shc family member functions in the insulin-like signaling pathway to enhance survival during L1 arrest

1
1. scibot 19 Nov 2025
  
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  CF1038
  
  DOI: 10.1093/genetics/iyae093
  
  Resource: (WB Cat# WBStrain00004840,RRID:WB-STRAIN:WBStrain00004840)
  
  Curator: @Apiekniewska
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11630764/
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Neuronal IL-17 controls Caenorhabditis elegans developmental diapause through CEP-1/p53

1
1. scibot 18 Nov 2025
  
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  Appendix 01
  
  DOI: 10.1073/pnas.2315248121
  
  Resource: (WB Cat# WBStrain00004840,RRID:WB-STRAIN:WBStrain00004840)
  
  Curator: @Apiekniewska
  
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pmc.ncbi.nlm.nih.gov/articles/PMC10963014/
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Sex-specific developmental gene expression atlas unveils dimorphic gene networks in C. elegans

1
1. scibot 18 Nov 2025
  
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  Supplementary Data 8
  
  DOI: 10.1038/s41467-024-48369-z
  
  Resource: (WB Cat# WBStrain00004840,RRID:WB-STRAIN:WBStrain00004840)
  
  Curator: @Apiekniewska
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11106331/
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Neuronal NPR-15 modulates molecular and behavioral immune responses via the amphid sensory neuron-intestinal axis in C. elegans

1
1. scibot 17 Nov 2025
  
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  CF1038
  
  DOI: 10.7554/eLife.90051
  
  Resource: (WB Cat# WBStrain00004840,RRID:WB-STRAIN:WBStrain00004840)
  
  Curator: @Apiekniewska
  
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pmc.ncbi.nlm.nih.gov/articles/PMC10942643/
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Dietary E. coli promotes age-dependent chemotaxis decline in C. elegans

1
1. scibot 17 Nov 2025
  
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  Supplementary Tables.
  
  DOI: 10.1038/s41598-024-52272-4
  
  Resource: (WB Cat# WBStrain00004840,RRID:WB-STRAIN:WBStrain00004840)
  
  Curator: @Apiekniewska
  
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pmc.ncbi.nlm.nih.gov/articles/PMC10918063/
Oct 2025
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The insulin/IGF signaling cascade modulates SUMOylation to regulate aging and proteostasis in Caenorhabditis elegans

1
1. scibot 16 Oct 2025
  
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  CF1038
  
  DOI: 10.7554/eLife.38635
  
  Resource: (WB Cat# WBStrain00004840,RRID:WB-STRAIN:WBStrain00004840)
  
  Curator: @sonofthor
  
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pmc.ncbi.nlm.nih.gov/articles/PMC6277199/
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Serotonin and Dopamine Mimic Glucose-Induced Reinforcement in C. elegans: Potential Role of NSM Neurons and the Serotonin Subtype 4 Receptor

1
1. scibot 13 Oct 2025
  
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  CF1038
  
  DOI: 10.3389/fphys.2021.783359
  
  Resource: (WB Cat# WBStrain00004840,RRID:WB-STRAIN:WBStrain00004840)
  
  Curator: @sonofthor
  
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pmc.ncbi.nlm.nih.gov/articles/PMC8721000/
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Starvation-induced changes in somatic insulin/IGF-1R signaling drive metabolic programming across generations

1
1. scibot 13 Oct 2025
  
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  CF1038
  
  DOI: 10.1126/sciadv.ade1817
  
  Resource: (WB Cat# WBStrain00004840,RRID:WB-STRAIN:WBStrain00004840)
  
  Curator: @sonofthor
  
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pmc.ncbi.nlm.nih.gov/articles/PMC10081852/
Nov 2024
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On the benefits of the tryptophan metabolite 3-hydroxyanthranilic acid in Caenorhabditis elegans and mouse aging

1
1. scibot 21 Nov 2024
  
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  CF1038
  
  DOI: 10.1038/s41467-023-43527-1
  
  Resource: (WB Cat# WBStrain00004840,RRID:WB-STRAIN:WBStrain00004840)
  
  Curator: @AleksanderDrozdz
  
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pmc.ncbi.nlm.nih.gov/articles/PMC10721613/
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Dendrobium Nobile Alcohol Extract Extends the Lifespan of Caenorhabditis elegans via hsf-1 and daf-16

1
1. scibot 21 Nov 2024
  
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  CF1038
  
  DOI: 10.3390/molecules29040908
  
  Resource: (WB Cat# WBStrain00004840,RRID:WB-STRAIN:WBStrain00004840)
  
  Curator: @AleksanderDrozdz
  
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pmc.ncbi.nlm.nih.gov/articles/PMC10891841/
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Phloretic acid requires the insulin/IGF-1 pathway and autophagy to enhance stress resistance and extend the lifespan of Caenorhabditis elegans

1
1. scibot 21 Nov 2024
  
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  CF1038
  
  DOI: 10.3389/fphar.2024.1384227
  
  Resource: (WB Cat# WBStrain00004840,RRID:WB-STRAIN:WBStrain00004840)
  
  Curator: @AleksanderDrozdz
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11004342/
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Cysteine protease cathepsin B promotes lysosome integrity to extend the lifespan of alternative day fasting worms

1
1. scibot 20 Nov 2024
  
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  CF1038
  
  DOI: 10.1111/acel.14286
  
  Resource: (WB Cat# WBStrain00004840,RRID:WB-STRAIN:WBStrain00004840)
  
  Curator: @bandrow
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11561666/
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Lactobacillus paracasei subsp. paracasei 2004 improves health and lifespan in Caenorhabditis elegans

1
1. scibot 20 Nov 2024
  
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  CF1038
  
  DOI: 10.1038/s41598-024-60580-y
  
  Resource: (WB Cat# WBStrain00004840,RRID:WB-STRAIN:WBStrain00004840)
  
  Curator: @AleksanderDrozdz
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11076489/
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Dimethylsulfoniopropionate (DMSP) Increases Longevity and Mitochondrial Function in Caenorhabditis elegans: Implications for the Role of the Global Sulfur Cycle in Terrestrial Ecosystems

1
1. scibot 20 Nov 2024
  
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  CF1038
  
  DOI: 10.1021/envhealth.3c00208
  
  Resource: (WB Cat# WBStrain00004840,RRID:WB-STRAIN:WBStrain00004840)
  
  Curator: @AleksanderDrozdz
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11504169/
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Calcineurin inhibition enhances Caenorhabditis elegans lifespan by defecation defects-mediated calorie restriction and nuclear hormone signaling

1
1. scibot 19 Nov 2024
  
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  CF1038
  
  DOI: 10.7554/eLife.89572
  
  Resource: (WB Cat# WBStrain00004840,RRID:WB-STRAIN:WBStrain00004840)
  
  Curator: @bandrow
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11530235/
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TSG Extends the Longevity of Caenorhabditis elegans by Targeting the DAF-16/SKN-1/SIR-2.1-Mediated Mitochondrial Quality Control Process

1
1. scibot 19 Nov 2024
  
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  upplementary Table S1
  
  DOI: 10.3390/antiox13091086
  
  Resource: (WB Cat# WBStrain00004840,RRID:WB-STRAIN:WBStrain00004840)
  
  Curator: @bandrow
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11428426/
May 2024
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Low-dose Naltrexone (LDN) extends healthspan and lifespan in C. elegans via SKN-1 activation

1
1. scibot 30 May 2024
  
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  RRID: WB-STRAIN:CF1038
  
  DOI: 10.1016/j.isci.2024.109949
  
  Resource: (WB Cat# WBStrain00004840,RRID:WB-STRAIN:WBStrain00004840)
  
  Curator: @evieth
  
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  RRID:WB-STRAIN:WBStrain00004840 DOI:10.1016/j.isci.2024.109949
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DOI:10.1016/j.isci.2024.109949

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ncbi.nlm.nih.gov/pmc/articles/PMC11126937/
Jan 2022
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NHR-80 senses the mitochondrial UPR to rewire citrate metabolism for lipid accumulation in Caenorhabditis elegans

1
1. scibot 12 Jan 2022
  
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  WBStrain00004840
  
  DOI: 10.1016/j.celrep.2021.110206
  
  Resource: (WB Cat# WBStrain00004840,RRID:WB-STRAIN:WBStrain00004840)
  
  Curator: @sophiastull
  
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sciencedirect.com/science/article/pii/S2211124721017101