BRCA1/2 mutation carriers diagnosed with breast cancer before age 50 years are prone to a worse survival,
Interestingly no real differentiation between ER status.
4 Matching Annotations
- Apr 2017
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academic.oup.com academic.oup.com
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We established a cohort of invasive breast cancer patients diagnosed younger than age 50 years in 10 Dutch hospitals between 1970 and 2003
Great sized cohort: 6478 breast carrier patients. 3.2% BRCA1 carriers and 1.2% BRCA2.
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www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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Gitelman syndrome (GS) is a rare autosomal recessively inherited salt-wasting tubulopathy associated with mutations in the SLC12A3 gene, which encodes for NaCl cotransporter (NCC) in the kidney
This is an astonishingly rare disease.
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meta.science meta.science
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Gitelman syndrome (GS)
This is an astonishingly rare mutation.
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