satra (LOG OUT) NEWS ABOUT DOWNLOAD CHANGES OF BRAIN ACTIVATION PRE- POST SHORT-TERM PSYCHODYNAMIC INPATIENT PSYCHOTHERAPY: AN FMRI STUDY OF PANIC DISORDER PATIENTS. Beutel ME, Stark R, Pan H, Silbersweig D, Dietrich S (2010) Psychiatry Res 184(2):96-104 [PubMed] [Neurosynth] [Full Text] Cognitive-behavioural interventions have been shown to change brain functioning. We used an emotional linguistic go/nogo functional magnetic resonance imaging (fMRI) design to determine changes of brain activation patterns of panic disorder (PD) patients following short-term psychodynamic inpatient treatment. Nine PD patients underwent fMRI before and after treatment; 18 healthy controls were scanned twice at the same interval (4 weeks). In the go/nogo design, responses to panic-specific negative words were compared with linguistically matched positive and neutral words. According to hypotheses, patients rated affective words more strongly than controls and selectively recalled negative vs. positive/neutral words. Before treatment, high limbic (hippocampus and amygdala) activation was accompanied by low prefrontal activation to negative words. Inhibition-related activation patterns indicated difficulties of behavioural regulation in emotional context. At treatment termination, panic-related symptoms had improved significantly, and fronto-limbic activation patterns were normalized. Our results indicate that short-term psychodynamic treatment leads to changes in fronto-limbic circuitry not dissimilar to previous findings on cognitive-behavioural treatments. Metadata MeSH descriptors BrainBrain MappingEmotionsFemaleHumansImage Processing, Computer-AssistedInhibition (Psychology)InpatientsMagnetic Resonance ImagingMaleNeuropsychological TestsPanic DisorderPsychotherapy, BriefTreatment Outcome Stereotaxic space MNI Talairach Number of subjects Experiments Title:(Empty) Caption:(Empty) X Y Z -23 -17 -9 -23 -17 -9 -23 -17 -9 -23 -11 -9 -23 -11 -9 -23 -11 -9 -60 -54 2 -60 -54 2 -60 -54 2 46 14 17 46 14 17 46 14 17 -20 -11 -9 -20 -11 -9 -20 -11 -9 -20 -14 -11 -20 -14 -11 -20 -14 -11 26 -19 -6 26 -19 -6 26 -19 -6 -14 -15 23 -14 -15 23 -14 -15 23 -43 1 24 -43 1 24 -43 1 24 -43 0 26 -43 0 26 -43 0 26 -41 41 -6 -41 41 -6 -41 41 -6 +Cognitive Atlas Tasks +Cognitive Atlas Cognitive Domains +BrainMap Behavioural Domains Table is correct No Discussion roberto (12/31/2013 8:09:11 AM) Locations in the 1st experiment are each repeated 3 times Post your comment brainspell by Roberto Toro is licensed under a Creative Commons Attribution-ShareAlike 3.0 Unported License.