A cautionary note: the results reported here should be examined skeptically given their reliance on the DE-SWAN (DESWAN) method for identifying age-dependent transitions across the lifespan. As shown in our recent preprint, https://www.biorxiv.org/content/10.64898/2026.06.24.734079v1, DE-SWAN is subject to artifacts that reflect the population structure and a failure to appropriately account for uncertainty in age-dependent bins.
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