Youtube does a very good job when it comes to key board only interactions. It is very accessible to use only a key board on the website.

Youtube's layout could be seen as complicated to understand from a cognitive point of view. The home page has the most going on and could be seen as confusing. Once you search something up, it is simple to see and use.

Youtube does not offer any screen reader assistance that is built into their app/website but they do allow a third party extension to help provide to the people who need it which is useful but not as helpful as if they had a program already within the app.

Youtube has closed captioning which is very accessible to people who need it.