Binswanger disease = subcortical vascular dementia from chronic hypertension → slow procession, inattention, forgetfulness (less severe than Alzheimer Disease), executive dysfunction, slow gait, urinary issues, and white matter hyperintensities with lacunes.

Trihexyphenidyl is a muscarinic receptor antagonist

It works best for dystonia.

Important side effects: 1. Cognitive decline / confusion (elderly) 2. Hallucinations 3. Dry mouth + urinary retention + constipation