10 Matching Annotations
  1. Sep 2025
  2. physoc.onlinelibrary.wiley.com physoc.onlinelibrary.wiley.com
    Physical activity and joint health: Implications for knee osteoarthritis disease pathophysiology and mechanics
    5
    1. TristanParaker04 29 Sep 2025
      There might potentially also be differential responses between those with knee OA and those without. Indications exist that individuals with OA might have a reduced capacity to sustain higher magnitudes or repetitions of loading. Collectively, these findings suggest an optimal zone of activity that balances joint health benefits without causing harm

      Though, sounding much like a concluding statement, this is the tie in point of all the research in this article; people without OA have a higher chance of forming OA without exercise and a sedentary lifestyle, but those with OA must find an optimal point-the moderate exercise balance that will improve joint health and other lifesyle benefits.

    2. TristanParaker04 29 Sep 2025
      These contrasting results suggest that a higher physical activity level may both attenuate or induce greater magnitudes of joint degeneration in middle-aged people or older adults without compromised joint health (e.g., cartilage defects) or knee OA

      While this part of the article reinforces the contradictions of OA, it is good to show why these myths persist. Like I have said before in previous annotations, MODERATE exercise is linked with recovery, but this section right here is not only in a higher age group, which is already linked with increased chance of OA in uncompromised adults, but also tethered to higher physical acivity levels or more intense activity.

    3. TristanParaker04 29 Sep 2025
      A meta-analysis of 54 randomized control trials with an overall high quality has demonstrated that exercise can significantly ameliorate knee OA illness by reducing pain, improving physical function and enhancing quality of life

      This is scientific consensus that exercise can be the first line of therapy and not just a secondary procedure to surgical precedence. Exercise is essential in lessening pain, improving physical function(mobility) and quality of life afterwards. In the rest of the passage it links OA intensity with body weight, and that there is a direct correlation with the amount of weight you put on the joint impacting it. Exercise helps with weight loss and therefore will lessen symptoms.

    4. TristanParaker04 29 Sep 2025
      This perception aligns with the persistent narrative that knee OA is a ‘wear and tear’ arthritis, whereby exercise results in anatomical damage, a conception that remains prevalent in medical, media and patient representations. However, this view oversimplifies the complex aetiology of the disease.

      Perception is the core of misconception, people believe that exercising will cause more damage to the joint, they believe that it will cause more pain, they believe that surgery may be better instead, but they are wrong. Moderate exercise with mobility instruction and improvement do nothing but help the joint strength and add preventative measures in all ages.

    5. TristanParaker04 29 Sep 2025
      However, there is a concerning perception that physical activity is harmful or damaging to the affected joint in this population. In fact, 69% of people with osteoarthritic knee pain hold the unconscious belief that exercise is more dangerous for them than for the average person without pain

      The perception that pain = inability to exercise, or that exercise will make pain worse is a belief that a lot of patients have, not only in this study. This goes to show that it is a broad misconception about exercise and recovery driven by belief and fears.

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    physoc.onlinelibrary.wiley.com/doi/10.1113/EP092240
  3. www.oarsijournal.com www.oarsijournal.com
    An educational review of cartilage repair: precepts & practice – myths & misconceptions – progress & prospects
    5
    1. TristanParaker04 29 Sep 2025
      But what is now needed is a revolutionary turnaround in our conception of cartilage repair and a more thorough and systematic approach to its evaluation. We should not stagnate, but break free of the bounds of our comfort zone as represented by the old well-worn ruts – the trusted, tried and tested tracks of yore

      Just as patients think that surgery is the only way to regaining lost cartilage and becoming normal or improving from an impaired state. Other options such as rehabilitation with exercise, and methods of movement will prove eventful as well. The misconceptions of recovery and improvement will be shattered with further research and prompt discovery.

    2. TristanParaker04 29 Sep 2025
      Neither microfracturing/microdrilling nor ACI is clinically effective in patients over 50 years of age, probably because the bone-marrow-derived (mesenchymal) stem cells (microfracturing technique) and the transplanted autologous chondrocytes (ACI-technique) suffer age-related losses in their potential to proliferate and differentiate

      This furthers my point in the connection between surgical matters and the rehabilitation standpoint. If you are over a certain age, decline is inevitable for people with OA. This is one of the main factors, those without healthy bodies; lack of exercise, also a preventative method when dealing with OA, are more susceptible to worsening in condition. Just like those who older have a harder time recovering from surgery.

    3. TristanParaker04 29 Sep 2025
      Microdrilling and microfracturing have been advocated chiefly for young patients, in whom good results (improved joint functionality and relief from pain in 60 to 80% of cases) have been reported56–5956.Sledge, S.L.Microfracture techniques in the treatment of osteochondral injuriesClin Sports Med. 2001; 20:365-377Full TextFull Text (PDF)PubMedGoogle Scholar57.Steadman, J.R. ∙ Briggs, K.K. ∙ Rodrigo, J.J. ...Outcomes of microfracture for traumatic chondral defects of the knee: average 11-year follow-upArthroscopy. 2003; 19:477-484Full TextFull Text (PDF)Scopus (508)PubMedGoogle Scholar58.Mithoefer, K. ∙ Williams, 3rd, R.J. ∙ Warren, R.F. ...The microfracture technique for the treatment of articular cartilage lesions in the knee. A prospective cohort studyJ Bone Joint Surg Am. 2005; 87:1911-1920CrossrefScopus (284)PubMedGoogle Scholar59.Asik, M. ∙ Ciftci, F. ∙ Sen, C. ...The microfracture technique for the treatment of full-thickness articular cartilage lesions of the knee: midterm resultsArthroscopy. 2008; 24:1214-1220Full TextFull Text (PDF)Scopus (39)PubMedGoogle Scholar, probably owing to the larger numbers and the higher activity-levels of the participating precursor-cell pools in these individuals, thereby leading to a more exuberant repair response than in older ones. Since there is some evidence that microdrilling and microfracturing are most effective in patients below 40 years of age6060.Kreuz, P.C. ∙ Erggelet, C. ∙ Steinwachs, M.R. ...Is microfracture of chondral defects in the knee associated with different results in patients aged 40 years or younger?Arthroscopy. 2006; 22:1180-1186Full TextFull Text (PDF)Scopus (144)PubMedGoogle Scholar, it is questionable whether these techniques would be appropriate for OA-patients, who are usually older, whose spontaneous tissue-repair potential is impoverished, and in whom the number and the availability of bone-marrow-derived stem cells is reduced61–6361.Caplan, A.I.Mesenchymal stem cellsJ Orthop Res. 1991; 9:641-650CrossrefPubMedGoogle Scholar62.Muraglia, A. ∙ Cancedda, R. ∙ Quarto, R.Clonal mesenchymal progenitors from human bone marrow differentiate in vitro according to a hierarchical modelJ Cell Sci. 2000; 113:1161-1166PubMedGoogle Scholar63.Pittenger, M.F. ∙ Mosca, J.D. ∙ McIntosh, K.R.Human mesenchymal stem cells: progenitor cells for cartilage, bone, fat and stromaCurr Top Microbiol Immunol. 2000; 251:3-11PubMedGoogle Scholar.

      Though my research is mainly focused on rehabilitation without the use of surgeries I thought that I might take a look at the other strategies and try to compare them to a non-surgical standpoint. This point is important in showing that younger people respond better to rehabilitation and recover at a greater speed than older people. Not only does their activity level, pertaining to exercise, matter, but the state of body matters. Age, exercise level, and follow up, which most people wont do if they believe that the surgery/rehabilitation otherwise will be quick and easy. But it is a process that patients fail to adhere to because of misconceptions in recovery; fears, beliefs, motivations, etc.

    4. TristanParaker04 29 Sep 2025
      Although joint pain is a common concomitant of OA, this symptom is not correlated with the size of the articular-cartilage lesion, and the mechanism underlying its generation is largely unknown

      This shows that while pain coincides with OA, it is not the signifier that severity of the articular cartilage lesion, most common in OA cases, is getting any worse as the pain increases. Patients often figure that pain=more harm.

    5. TristanParaker04 29 Sep 2025
      Once the process of lesioning has begun, it cannot be arrested, but progresses inexorably with time,

      What this small sentence talks about is that intensification of the disease occurs naturally separate from moderate exercise and with careful analyzation of the article and my topic, the misconception that regular exercise(Intense exercise being an exception) is harmful to joints is just that, a misconception.

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    oarsijournal.com/article/S1063-4584(14)01383-1/fulltext