5 Matching Annotations
  1. Jun 2017
    1. (NS1, NS2A, NS2B, NS3, NS4A, NS4B, NS5) are involved in the construction of the replication complex which is key to successful RNA replication

      These are coded in the polyprotein, a hallmark of flaviviruses, but also seen in Human Rhinovirus, as the polyprotein codes similrly for 11 proteins, some functioning as replication complex.

    1. translated protein gets cleaved by virally encoded proteases and then yields

      Coding for a single polyprotein is also common for flaviviruses like Human Rhinovirus, and then getting cleaved into proteins that assist in replication process.

  2. Apr 2017