Hippocrates (460-377 B.C.E.) , who believed that it was the brain and not the heart where the locus of the mind resided. He wrote: "It ought to be generally known that the source of our pleasure, merriment, laughter, and amusement, as of our grief, pain, anxiety, and tears is none other than the brain. It is specially the organ which enables us to think, see, and hear......It is the brain too which is the seat of madness and delirium, of the fears and frights which assail us" (Gross, 1987, p. 843-844).
it was Hippocrates who really understood that it was the brain that housed each function that contributed to human behavior