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  1. Last 7 days
  2. www.nature.com www.nature.com
    Ultraprocessed or minimally processed diets following healthy dietary guidelines on weight and cardiometabolic health: a randomized, crossover trial
    3
    1. mgha245 13 Feb 2026
      n this study, both MPF and UPF diets following national healthy dietary guidance resulted in percentage weight loss after 8 weeks, with significantly greater reductions on the MPF diet. Greater weight, BMI and fat mass loss were also observed on the MPF compared with the UPF diet, as well as greater reductions in triglycerides and cravings. Conversely, LDL-C was lower on the UPF diet. Overall, these results suggest favorable changes in body composition and craving control from adhering to national dietary guidance with a diet of MPF rather than UPF.

      Although both groups lost weight, the MPF group lost more fat mass. This is important to note since not all weight loss is good weight loss (ex: loss of lean mass).

    2. mgha245 13 Feb 2026
      national healthy dietary guidance

      This may suggest that the dietary guidelines are clinically effective in achieving a healthy weight/overall optimal health

    3. mgha245 13 Feb 2026
      Weight and BMI were significantly lower at 8 weeks from baseline on both diets. Waist circumference and waist-to-height ratio did not differ significantly. Reductions in weight (−0.96 kg (s.e., 0.40); P = 0.019) and BMI (−0.34 kg m−2 (s.e., 0.14); P = 0.021) were significantly greater on the MPF versus UPF diet, with no significant differences in waist circumference.

      These results make me think that individuals may have been falsely reporting typical UPF and or calorie intake, especially since they lost weight on both diets.

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    nature.com/articles/s41591-025-03842-0
  3. bmjopen.bmj.com bmjopen.bmj.com
    UPDATE trial: investigating the effects of ultra-processed versus minimally processed diets following UK dietary guidance on health outcomes: a protocol for an 8-week community-based cross-over randomised controlled trial in people with overweight or obesity, followed by a 6-month behavioural intervention
    4
    1. mgha245 13 Feb 2026
      using bioelectrical impedance analysis

      I like that the study uses BIA to assess body composition and not just BMI, which does not account for lean vs fat mass

    3. mgha245 13 Feb 2026
      randomised controlled trial include the long 8-week duration of each intervention diet, and provision of all food and drink to participants’ homes to provide

      The study type (randomized control) and the highly controlled intervention (food delivered to home based on diet type) are great strengths. They make this study more replicable and leave less room for error.

    4. mgha245 13 Feb 2026
      UK dietary energy source

      It is interesting to me that UPFs are the main dietary source of energy in Europe. I feel like Americans are constantly comparing their diets to those living in Europe and stating they eat much less processed foods.

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    bmjopen.bmj.com/content/14/3/e079027
  4. Feb 2026
  5. www.mdpi.com www.mdpi.com
    Oxidative Stress and Inflammatory Biomarkers Are Related to High Intake of Ultra-Processed Food in Old Adults with Metabolic Syndrome
    3
    1. mgha245 04 Feb 2026
      The most outstanding result of this study is that a high UPF intake promotes a more pro-oxidant and pro-inflammatory status in patients with MetS without differences in their anthropometric parameters and biochemical profile.

      This shows that inflammation may differ among individuals of different weights, heights, etc. Although obesity/excess fat can increase inflammation, so can several other factors. I wonder how they could limit more of those in future studies.

    2. mgha245 04 Feb 2026
      differences in the levels of endogenous antioxidants and prooxidants

      This shows that antioxidant levels and pro-oxidant levels may be independent of one another and not strictly an inverse relationship, interesting

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    mdpi.com/2076-3921/12/8/1532
  6. Jan 2026
  7. www.clinicalkey.com www.clinicalkey.com
    T Cell–Mediated Immunity: Activation of T Lymphocytes by Cell-Associated Antigens- ClinicalKey
    5
    2. mgha245 25 Jan 2026
      while processed and ultra-processed foods represented, respectively, 25.2% (SD ± 12.2) and 10.8%

      This was lower than I expected, which may be due to the date of the study.

    3. mgha245 25 Jan 2026
      tegorized according to the NOVA classification is available as

      This method relies on subject's self-reports of diet, which makes me question the validity. People tend to overestimate or underestimate their food intake.

    4. mgha245 25 Jan 2026
      2005-2010

      This was a long time ago. While this still may be a popular and relevant topic, I have been taught at UK that we should try to look at articles in the last 5-10 years.

    5. mgha245 25 Jan 2026
      micronutrients

      I feel like more concrete examples could have been given here. Maybe even a chart. The explanation of the 4 levels of processed foods is a bit confusing and wordy.

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    clinicalkey.com/