24 Matching Annotations
  1. Jun 2017
  2. May 2017
  3. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    1. It uses pili with the aid of protease enzymes in attachment to epithelial cells, such as in the respiratory tract.  The bacterium has capsules or slime layers that protect it from antibodies, lymphocytes, and phagocytes.  In order to invade tissues, it produces extracellular enzymes such as elastase and alkaline protease.  There are also three soluble proteins involved in invasion, which are cytotoxin (mw 25 kDa) and two hemolysins.  It produces the extracellular toxins Exoenzyme S and Exotoxin A and also LPS, which is characteristic of Gram-negative bacteria.  All of these characteristics lead to a wide variety of diseases.

      virulence factors

    2. The bacterium is very low-maintenance when it comes nutrition.  It does not require organic growth factors, and can use over seventy-five organic compounds for growth.  In a lab setting, acetate and ammonium sulfate in a medium will satisfy it.  The optimum growth temperature is 37 degrees C, but it can grow in temperatures up to 42 degrees C.  Not only is it tolerant to temperature, but also to salts and dyes, weak antiseptics, and antibiotics.

      growth conditions

    1. he recommended procedure for isolating Neisseria gonorrhoeae involves the inoculation of a specimen directly onto a nutritive growth medium that is at room temperature and immediate incubation at 35-37ºC in an atmosphere of 3 – 10% added CO2

      Some aspects of growing conditions

    2. The organism is usually found interacellulary in polymorphonuclear leukocytes, or a specific category of white blood cells with varying shapes of nuclei, of the gonorrhea pustular exudates [8] with humans as its only natural host

      Answer to question 4: Where is the organism found normally?

  4. Apr 2017