This is a solid post on the whole, but it never connects to the issues of posthumanism. For instance, what is it about the highly mediated world that Spider lives in that might be driving him. Why might the city of Transmetropolitan be host to so many religions?
Furthermore, it doesn't really delve into specifics but rather provides a somewhat cursory summary of Spider's actions. Because it is cursory, you aren't able to deal with the contradictions of Spider's character. There are elements of the story that show Spider to be anything but compassionate and humane. Indeed, what might be taken away is that his pursuit of truth, which is his primary pursuit, works in opposition to compassion. Certainly, these two pursuits aren't mutually exclusive, but their relationship is very complex.