It is supposed probable that a building of somewhat more size in the middle of the grounds may be called for in time, in which may be rooms for religious worship
This central building sounds like it could have been the Rotunda. It's strange that a place for religious worship would be considered at the center of the grounds since Jefferson always put so much emphasis on a university focused on academics rather than religion. It makes sense that there would be a church, but having it in the center when this document directly addresses an absence of religious studies is very contradictory.
-Wei Guan