501 Matching Annotations
  1. Last 7 days
  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    ARID1A governs the silencing of sex-linked transcription during male meiosis in the mouse
    7
    1. scibot 04 Jan 2025
      RRID:AB_309864

      Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers

      RRID:AB_309864
    2. scibot 03 Jan 2025
      RRID:AB_309864

      Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers

      RRID:AB_309864
    3. scibot 02 Jan 2025
      RRID:AB_309864

      Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers

      RRID:AB_309864
    4. scibot 01 Jan 2025
      RRID:AB_309864

      Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers

      RRID:AB_309864
    5. scibot 31 Dec 2024
      RRID:AB_309864

      Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers

      RRID:AB_309864
    6. scibot 30 Dec 2024
      RRID:AB_309864

      Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers

      RRID:AB_309864
    7. scibot 29 Dec 2024
      RRID:AB_309864

      Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers

      RRID:AB_309864
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    pmc.ncbi.nlm.nih.gov/articles/PMC11594533/
  3. www.cell.com www.cell.com
    TFEB triggers a matrix degradation and invasion program in triple-negative breast cancer cells upon mTORC1 repression
    1
    1. scibot 29 Dec 2024
      RRID:AB_309864

      DOI: 10.1016/j.devcel.2024.12.005

      Resource: (Millipore Cat# 05-636, RRID:AB_309864)

      Curator: @scibot

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    cell.com/developmental-cell/fulltext/S1534-5807(24)00727-5
  4. Dec 2024
  5. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    ARID1A governs the silencing of sex-linked transcription during male meiosis in the mouse
    27
    1. scibot 28 Dec 2024
      RRID:AB_309864

      Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers

      RRID:AB_309864
    2. scibot 27 Dec 2024
      RRID:AB_309864

      Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers

      RRID:AB_309864
    3. scibot 26 Dec 2024
      RRID:AB_309864

      Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers

      RRID:AB_309864
    4. scibot 25 Dec 2024
      RRID:AB_309864

      Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers

      RRID:AB_309864
    5. scibot 24 Dec 2024
      RRID:AB_309864

      Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers

      RRID:AB_309864
    6. scibot 23 Dec 2024
      RRID:AB_309864

      Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers

      RRID:AB_309864
    7. scibot 22 Dec 2024
      RRID:AB_309864

      Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers

      RRID:AB_309864
    8. scibot 20 Dec 2024
      RRID:AB_309864

      Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers

      RRID:AB_309864
    9. scibot 19 Dec 2024
      RRID:AB_309864

      Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers

      RRID:AB_309864
    10. scibot 18 Dec 2024
      RRID:AB_309864

      Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers

      RRID:AB_309864
    11. scibot 17 Dec 2024
      RRID:AB_309864

      Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers

      RRID:AB_309864
    12. scibot 16 Dec 2024
      RRID:AB_309864

      Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers

      RRID:AB_309864
    13. scibot 15 Dec 2024
      RRID:AB_309864

      Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers

      RRID:AB_309864
    14. scibot 14 Dec 2024
      RRID:AB_309864

      Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers

      RRID:AB_309864
    15. scibot 13 Dec 2024
      RRID:AB_309864

      Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers

      RRID:AB_309864
    16. scibot 12 Dec 2024
      RRID:AB_309864

      Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers

      RRID:AB_309864
    17. scibot 11 Dec 2024
      RRID:AB_309864

      Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers

      RRID:AB_309864
    18. scibot 10 Dec 2024
      RRID:AB_309864

      Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers

      RRID:AB_309864
    19. scibot 09 Dec 2024
      RRID:AB_309864

      Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers

      RRID:AB_309864
    20. scibot 08 Dec 2024
      RRID:AB_309864

      Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers

      RRID:AB_309864
    21. scibot 07 Dec 2024
      RRID:AB_309864

      Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers

      RRID:AB_309864
    22. scibot 06 Dec 2024
      RRID:AB_309864

      Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers

      RRID:AB_309864
    23. scibot 05 Dec 2024
      RRID:AB_309864

      Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers

      RRID:AB_309864
    24. scibot 04 Dec 2024
      RRID:AB_309864

      Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers

      RRID:AB_309864
    25. scibot 03 Dec 2024
      RRID:AB_309864

      Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers

      RRID:AB_309864
    26. scibot 02 Dec 2024
      RRID:AB_309864

      Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers

      RRID:AB_309864
    27. scibot 01 Dec 2024
      RRID:AB_309864

      Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers

      RRID:AB_309864
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    pmc.ncbi.nlm.nih.gov/articles/PMC11594533/
  6. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    PFKFB3-dependent redox homeostasis and DNA repair support cell survival under EGFR-TKIs in non-small cell lung carcinoma
    1
    1. scibot 22 Dec 2024
      RRID:AB_309864

      DOI: 10.1186/s40170-024-00366-y

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    pmc.ncbi.nlm.nih.gov/articles/PMC11658331/
  7. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Mouse Pachytene piRNAs Cleave Hundreds of Transcripts, But Alter the Steady-State Abundance of Only a Minority of Targets
    1
    1. scibot 21 Dec 2024
      RRID:AB_309864

      DOI: 10.1101/2024.11.02.621675

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    pmc.ncbi.nlm.nih.gov/articles/PMC11566022/
  8. www.sciencedirect.com www.sciencedirect.com
    MAPK14/p38α shapes the molecular landscape of endometrial cancer and promotes tumorigenic characteristics
    1
    1. scibot 21 Dec 2024
      RRID:AB_309864

      DOI: 10.1016/j.celrep.2024.115104

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    sciencedirect.com/science/article/pii/S2211124724014554
  9. www.science.org www.science.org
    Polygenic risk for alcohol use disorder affects cellular responses to ethanol exposure in a human microglial cell model
    1
    1. scibot 20 Dec 2024
      RRID:AB_309864

      DOI: 10.1126/sciadv.ado5820

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    science.org/doi/10.1126/sciadv.ado5820
  10. www.sciencedirect.com www.sciencedirect.com
    Mapping functional elements of the DNA damage response through base editor screens
    1
    1. scibot 12 Dec 2024
      RRID:AB_309864

      DOI: 10.1016/j.celrep.2024.115047

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    sciencedirect.com/science/article/pii/S2211124724013986
  11. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Control of cell proliferation by memories of mitosis
    1
    1. scibot 11 Dec 2024
      RRID:AB_309864

      DOI: 10.1126/science.add9528

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    pmc.ncbi.nlm.nih.gov/articles/PMC11621110/
  12. www.sciencedirect.com www.sciencedirect.com
    Classification and functional characterization of regulators of intracellular STING trafficking identified by genome-wide optical pooled screening
    1
    1. scibot 10 Dec 2024
      RRID:AB_309864

      DOI: 10.1016/j.cels.2024.11.004

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    sciencedirect.com/science/article/pii/S2405471224003375
  13. www.cell.com www.cell.com
    UBA1 inhibition sensitizes cancer cells to PARP inhibitors
    1
    1. scibot 05 Dec 2024
      RRID:AB_309864

      DOI: 10.1016/j.xcrm.2024.101834

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    cell.com/cell-reports-medicine/fulltext/S2666-3791(24)00605-0
  14. Nov 2024
  15. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    ARID1A governs the silencing of sex-linked transcription during male meiosis in the mouse
    2
    1. scibot 29 Nov 2024
      RRID:AB_309864

      Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers

      RRID:AB_309864
    2. scibot 28 Nov 2024
      RRID:AB_309864

      Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers

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    pmc.ncbi.nlm.nih.gov/articles/PMC11594533/
  16. www.sciencedirect.com www.sciencedirect.com
    STK19 facilitates the clearance of lesion-stalled RNAPII during transcription-coupled DNA repair
    1
    1. scibot 21 Nov 2024
      RRID:AB_309864

      DOI: 10.1016/j.cell.2024.10.018

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    sciencedirect.com/science/article/pii/S0092867424012005
  17. www.sciencedirect.com www.sciencedirect.com
    Profound synthetic lethality between SMARCAL1 and FANCM
    1
    1. scibot 17 Nov 2024
      RRID:AB_309864

      DOI: 10.1016/j.molcel.2024.10.016

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    sciencedirect.com/science/article/pii/S1097276524008566
  18. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Polygenic risk for alcohol use disorder affects cellular responses to ethanol exposure in a human microglial cell model
    1
    1. scibot 15 Nov 2024
      RRID:AB_309864

      DOI: 10.1126/sciadv.ado5820

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    pmc.ncbi.nlm.nih.gov/articles/PMC11546823/
  19. www.sciencedirect.com www.sciencedirect.com
    A p38 MAPK-ROS axis fuels proliferation stress and DNA damage during CRISPR-Cas9 gene editing in hematopoietic stem and progenitor cells
    1
    1. scibot 14 Nov 2024
      RRID:AB_309864

      DOI: 10.1016/j.xcrm.2024.101823

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    sciencedirect.com/science/article/pii/S2666379124005949
  20. www.sciencedirect.com www.sciencedirect.com
    Acute multi-level response to defective de novo chromatin assembly in S-phase
    1
    1. scibot 14 Nov 2024
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      DOI: 10.1016/j.molcel.2024.10.023

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    sciencedirect.com/science/article/pii/S1097276524008633
  21. www.sciencedirect.com www.sciencedirect.com
    CRISPRi/a screens in human iPSC-cardiomyocytes identify glycolytic activation as a druggable target for doxorubicin-induced cardiotoxicity
    1
    1. scibot 11 Nov 2024
      RRID:AB_309864

      DOI: 10.1016/j.stem.2024.10.007

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    sciencedirect.com/science/article/pii/S1934590924003692
  22. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Targeting Catechol-O-Methyltransferase Induces Mitochondrial Dysfunction and Enhances the Efficacy of Radiotherapy in Glioma
    1
    1. scibot 08 Nov 2024
      RRID:AB_309864

      DOI: 10.1158/0008-5472.CAN-24-0134

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    pmc.ncbi.nlm.nih.gov/articles/PMC11532787/
  23. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Laminin-α2 chain deficiency in skeletal muscle causes dysregulation of multiple cellular mechanisms
    1
    1. scibot 07 Nov 2024
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      DOI: 10.26508/lsa.202402829

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  24. Oct 2024
  25. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    NAPRT silencing in FH-deficient renal cell carcinoma confers therapeutic vulnerabilities via NAD+ depletion
    1
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  26. Sep 2024
  27. www.sciencedirect.com www.sciencedirect.com
    Endometrial Axin2+ Cells Drive Epithelial Homeostasis, Regeneration, and Cancer following Oncogenic Transformation
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      DOI: 10.1016/j.stem.2019.11.012

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    sciencedirect.com/science/article/pii/S1934590919304679
  28. www.sciencedirect.com www.sciencedirect.com
    Cell-Cycle Asynchrony Generates DNA Damage at Mitotic Entry in Polyploid Cells
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      DOI: 10.1016/j.cub.2019.09.041

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    Acquired Resistance of EGFR-Mutated Lung Cancer to Tyrosine Kinase Inhibitor Treatment Promotes PARP Inhibitor Sensitivity
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  30. www.sciencedirect.com www.sciencedirect.com
    ATR-Mediated Global Fork Slowing and Reversal Assist Fork Traverse and Prevent Chromosomal Breakage at DNA Interstrand Cross-Links
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  31. Aug 2024
  32. www.sciencedirect.com www.sciencedirect.com
    Histone chaperone HIRA, promyelocytic leukemia protein, and p62/SQSTM1 coordinate to regulate inflammation during cell senescence
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    RAD51 protects abasic sites to prevent replication fork breakage
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  34. www.biorxiv.org www.biorxiv.org
    Systematic identification of Y-chromosome gene functions in mouse spermatogenesis
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  35. 52.53.155.43 52.53.155.43
    PARG-deficient tumor cells have an increased dependence on EXO1/FEN1-mediated DNA repair
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  36. www.embopress.org www.embopress.org
    DNA damage response at telomeres boosts the transcription of SARS-CoV-2 receptor ACE2 during aging
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  37. academic.oup.com academic.oup.com
    The adeno-associated virus 2 (AAV2) genome and rep 68/78 proteins interact with cellular sites of DNA damage
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  38. www.embopress.org www.embopress.org
    Paternal USP26 mutations raise Klinefelter syndrome risk in the offspring of mice and humans
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      γH2AX

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  39. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    E2F1-associated purine synthesis pathway is a major component of the MET-DNA damage response network
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  40. Jul 2024
  41. 52.53.155.43 52.53.155.43
    PPAR_Interaction_with_UBR5_ATMIN_Promot-html.html
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  42. www.sciencedirect.com www.sciencedirect.com
    G2 arrest primes hematopoietic stem cells for megakaryopoiesis
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  43. 52.53.155.43 52.53.155.43
    paul-chowdhuri-das-2024-tdp1-phosphorylation-by-cdk1-in-mitosis-promotes-mus81-dependent-repair-of-trapped-top1-dna-html.html
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  44. www.embopress.org www.embopress.org
    TDP1 phosphorylation by CDK1 in mitosis promotes MUS81-dependent repair of trapped Top1-DNA covalent complexes
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  45. www.mdpi.com www.mdpi.com
    Upregulation of TET2 and Resistance to DNA Methyltransferase (DNMT) Inhibitors in DNMT1-Deleted Cancer Cells
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      DOI: 10.3390/diseases12070163

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  46. www.cell.com www.cell.com
    PARP1-driven repair of topoisomerase IIIα DNA-protein crosslinks by FEN1
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    cell.com/cell-reports/fulltext/S2211-1247(24)00851-9
  47. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Characterising replisome disassembly in human cells
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      AB_309864

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  48. www.science.org www.science.org
    TERRA transcripts localize at long telomeres to regulate telomerase access to chromosome ends
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      DOI: 10.1126/sciadv.adk4387

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  49. Jun 2024
  50. www.sciencedirect.com www.sciencedirect.com
    Suppressed basal mitophagy drives cellular aging phenotypes that can be reversed by a p62-targeting small molecule
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  51. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    TERRA transcripts localize at long telomeres to regulate telomerase access to chromosome ends
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  52. www.sciencedirect.com www.sciencedirect.com
    The ribotoxic stress response drives UV-mediated cell death
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  53. 52.53.155.43 52.53.155.43
    2024.05.31.596483v1.full-html.html
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  54. May 2024
  55. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Chloroquine-induced DNA damage synergizes with DNA repair inhibitors causing cancer cell death
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  56. aacrjournals.org aacrjournals.org
    PKCð regulates chromatin remodeling and DNA repair through SIRT6
    2
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      Catalog no. 05–636, RRID:AB_309864, Millipore

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      Catalog no. 05–636, RRID:AB_309864, Millipore

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    aacrjournals.org/mcr/article/22/2/181/733696/PKC-Regulates-Chromatin-Remodeling-and-DNA-Repair
  57. aacrjournals.org aacrjournals.org
    Preclinical Characterization of AZD9574, a Blood-Brain Barrier Penetrant Inhibitor of PARP1
    2
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    aacrjournals.org/clincancerres/article/30/7/1338/741831/Preclinical-Characterization-of-AZD9574-a-Blood
  58. www.sciencedirect.com www.sciencedirect.com
    TDP1 mutation causing SCAN1 neurodegenerative syndrome hampers the repair of transcriptional DNA double-strand breaks
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  59. www.biorxiv.org www.biorxiv.org
    Deregulation of multiple mechanisms shapes the onset of LAMA2-congenital muscular dystrophy
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  60. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    NRDE2 deficiency impairs homologous recombination repair and sensitizes hepatocellular carcinoma to PARP inhibitors
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  61. Apr 2024
  62. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Classification and functional characterization of regulators of intracellular STING trafficking identified by genome-wide optical pooled screening
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  63. rupress.org rupress.org
    DUX4-induced HSATII transcription causes KDM2A/B-PRC1 nuclear foci and impairs DNA damage response
    2
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  64. www.sciencedirect.com www.sciencedirect.com
    Principles of chromosome organization for meiotic recombination
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  65. aacrjournals.org aacrjournals.org
    AXL/WRNIP1 mediates replication stress response and promotes therapy resistance and metachronous metastasis in HER2+ breast cancer
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      DOI: 10.1158/0008-5472.CAN-23-1459

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    RAD52-dependent mitotic DNA synthesis is required for genome stability in Cyclin E1-overexpressing cells
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    PARG-deficient tumor cells have an increased dependence on EXO1/FEN1-mediated DNA repair
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    DNA-PK and ATM drive phosphorylation signatures that antagonistically regulate cytokine responses to herpesvirus infection or DNA damage
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    A rewiring of DNA replication mediated by MRE11 exonuclease underlies primed-to-naive cell de-differentiation
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    GCN5 mediates DNA-PKcs crotonylation for DNA double-strand break repair and determining cancer radiosensitivity
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    The SPATA5-SPATA5L1 ATPase complex directs replisome proteostasis to ensure genome integrity
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    BRCA1 and 53BP1 regulate reprogramming efficiency by mediating DNA repair pathway choice at replication-associated double-strand breaks
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  73. Mar 2024
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    Transcription elongation defects link oncogenic SF3B1 mutations to targetable alterations in chromatin landscape
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    A TOPBP1 allele causing male infertility uncouples XY silencing dynamics from sex body formation
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    Improved detection of colibactin-induced mutations by genotoxic E. coli in organoids and colorectal cancer
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    The sirtuin-associated human senescence program converges on the activation of placenta-specific gene PAPPA
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    CDK-independent role of D-type cyclins in regulating DNA mismatch repair
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    AurkA/TPX2 co-overexpression in nontransformed cells promotes genome instability through induction of chromosome mis-segregation and attenuation of the p53 signalling pathway
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    RTF2 controls replication repriming and ribonucleotide excision at the replisome
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    A di-acetyl-decorated chromatin signature couples liquid condensation to suppress DNA end synapsis
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    The proteomic landscape of genotoxic stress-induced micronuclei
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    A Phase 1 Expansion Cohort Study Evaluating the Safety and Efficacy of the CHK1 Inhibitor LY2880070 with Low-Dose Gemcitabine in Metastatic Pancreatic Adenocarcinoma Patients
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    A synergistic two-drug therapy specifically targets a DNA repair dysregulation that occurs in p53-deficient colorectal and pancreatic cancers
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    Specialized replication mechanisms maintain genome stability at human centromeres
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    Integrative modeling uncovers p21-driven drug resistance and prioritizes therapies for PIK3CA-mutant breast cancer
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    BLM and BRCA1-BARD1 coordinate complementary mechanisms of joint DNA molecule resolution
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    The male pachynema-specific protein MAPS drives phase separation in vitro and regulates sex body formation and chromatin behaviors in vivo
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    The FANCI/FANCD2 complex links DNA damage response to R-loop regulation through SRSF1-mediated mRNA export
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    Metabolic regulation of homologous recombination repair by MRE11 lactylation
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    Ethanol induces replication fork stalling and membrane stress in immortalized laryngeal cells
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    PRMT blockade induces defective DNA replication stress response and synergizes with PARP inhibition
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    Topoisomerase 1 Inhibition in MYC-Driven Cancer Promotes Aberrant R-Loop Accumulation to Induce Synthetic Lethality
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    Irreversible inhibition of TRF2TRFH recruiting functions by a covalent cyclic peptide induces telomeric replication stress in cancer cells
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  107. Nov 2023
  108. www.cell.com www.cell.com
    Oncogenic signals prime cancer cells for toxic cell overgrowth during a G1 cell cycle arrest
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    Pharmacological depletion of RNA splicing factor RBM39 by indisulam synergizes with PARP inhibitors in high-grade serous ovarian carcinoma
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    Widespread BRCA1/2-independent homologous recombination defects are caused by alterations in RNA-binding proteins
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  111. Oct 2023
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    Cellular senescence promotes progenitor cell expansion during axolotl limb regeneration
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    Genome-wide CRISPR activation screening in senescent cells reveals SOX5 as a driver and therapeutic target of rejuvenation
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    Tumor-resident Lactobacillus iners confer chemoradiation resistance through lactate-induced metabolic rewiring
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    TERRA R-loops connect and protect sister telomeres in mitosis
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    Effector memory T cells induce innate inflammation by triggering DNA damage and a non-canonical STING pathway in dendritic cells
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    DNA damage induces nuclear envelope rupture through ATR-mediated phosphorylation of lamin A/C
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  118. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The Designer Drug αPHP Affected Cell Proliferation and Triggered Deathly Mechanisms in Murine Neural Stem/Progenitor Cells
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    Replication stress and defective checkpoints make fallopian tube epithelial cells putative drivers of high-grade serous ovarian cancer
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  120. Sep 2023
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    Targeting MCL-1 triggers DNA damage and an anti-proliferative response independent from apoptosis induction
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    Neuronal DNA double-strand breaks lead to genome structural variations and 3D genome disruption in neurodegeneration
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    The interplay of TARG1 and PARG protects against genomic instability
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  124. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Discovery and Characterization of ZL-2201, a Potent, Highly Selective, and Orally Bioavailable Small-molecule DNA-PK Inhibitor
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  125. Aug 2023
  126. www.sciencedirect.com www.sciencedirect.com
    Genetic dissection of crossover mutants defines discrete intermediates in mouse meiosis
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    Aberrant accumulation of Kras-dependent pervasive transcripts during tumor progression renders cancer cells dependent on PAF1 expression
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  128. 52.53.155.43 52.53.155.43
    ATF7IP2, a meiosis-specific partner of SETDB1, is required for proper chromosome remodeling and crossover formation during spermatogenesis
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  129. Jul 2023
  130. www.sciencedirect.com www.sciencedirect.com
    CCDC176 stabilizes microtubule doublets 1 and 9 to ensure proper sperm movement
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    Nucleocytoplasmic mRNA redistribution accompanies RNA binding protein mislocalization in ALS motor neurons and is restored by VCP ATPase inhibition
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    Biphasic JNK-Erk signaling separates the induction and maintenance of cell senescence after DNA damage induced by topoisomerase II inhibition
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    Genome-scale mapping of DNA damage suppressors through phenotypic CRISPR-Cas9 screens
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    Kinome-wide CRISPR-Cas9 knockout screens revealed PLK1 as a therapeutic target for osteosarcoma
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    Transcriptional metabolic reprogramming implements meiotic fate decision in mouse testicular germ cells
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  136. Jun 2023
  137. faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com
    A DNA damage response-like phenotype defines a third of colon cancers at onset
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  138. www.nature.com www.nature.com
    Relaxed targeting rules help PIWI proteins silence transposons
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    Integrator facilitates RNAPII removal to prevent transcription-replication collisions and genome instability
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    Characterizing microglial senescence: Tau as a key player
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  141. www.nature.com www.nature.com
    Serine ADP-ribosylation in Drosophila provides insights into the evolution of reversible ADP-ribosylation signalling
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    Lineage skewing and genome instability underlie marrow failure in a zebrafish model of GATA2 deficiency
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  143. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Endonuclease VIII-like 1 deficiency potentiates nigrostriatal dopaminergic neuron degeneration in a male mouse model of Parkinson's disease
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  144. www.biorxiv.org www.biorxiv.org
    PKCδ regulates chromatin remodeling and DNA repair through SIRT6
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    Nuclear lamina erosion-induced resurrection of endogenous retroviruses underlies neuronal aging
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  146. May 2023
  147. www.sciencedirect.com www.sciencedirect.com
    MND1 and PSMC3IP control PARP inhibitor sensitivity in mitotic cells
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    Replication stress impairs chromosome segregation and preimplantation development in human embryos
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  149. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Repurposing ceritinib induces DNA damage and enhances PARP inhibitor responses in high-grade serous ovarian carcinoma
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    1. scibot 05 May 2023
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      DOI: 10.1158/0008-5472.CAN-21-0732

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  150. Apr 2023
  151. www.sciencedirect.com www.sciencedirect.com
    Modular antibodies reveal DNA damage-induced mono-ADP-ribosylation as a second wave of PARP1 signaling
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  152. www.sciencedirect.com www.sciencedirect.com
    A living biobank of patient-derived ductal carcinoma in situ mouse-intraductal xenografts identifies risk factors for invasive progression
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  153. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Polymerase iota (Pol ι) prevents PrimPol-mediated nascent DNA synthesis and chromosome instability
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      DOI: 10.1126/sciadv.ade7997

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  154. www.science.org www.science.org
    Polymerase iota (Pol ι) prevents PrimPol-mediated nascent DNA synthesis and chromosome instability
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  155. www.sciencedirect.com www.sciencedirect.com
    TERRA stability is regulated by RALY and polyadenylation in a telomere-specific manner
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  156. www.sciencedirect.com www.sciencedirect.com
    SLFN5-mediated chromatin dynamics sculpt higher-order DNA repair topology
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  157. www.sciencedirect.com www.sciencedirect.com
    ERCC6L2 mitigates replication stress and promotes centromere stability
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  158. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    TZAP overexpression induces telomere dysfunction and ALT-like activity in ATRX/DAXX deficient cells
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  159. Mar 2023
  160. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    TZAP overexpression induces telomere dysfunction and ALT-like activity in ATRX/DAXX deficient cells
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  161. www.sciencedirect.com www.sciencedirect.com
    DNA-damaged podocyte-CD8 T cell crosstalk exacerbates kidney injury by altering DNA methylation
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  162. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Loss of the Volume-regulated Anion Channel Components LRRC8A and LRRC8D Limits Platinum Drug Efficacy
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      DOI: 10.1158/2767-9764.CRC-22-0208

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  163. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Drug–gene Interaction Screens Coupled to Tumor Data Analyses Identify the Most Clinically Relevant Cancer Vulnerabilities Driving Sensitivity to PARP Inhibition
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  164. www.sciencedirect.com www.sciencedirect.com
    m6A-driven SF3B1 translation control steers splicing to direct genome integrity and leukemogenesis
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  165. www.sciencedirect.com www.sciencedirect.com
    HNRNPU facilitates antibody class-switch recombination through C-NHEJ promotion and R-loop suppression
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    sciencedirect.com/science/article/pii/S2211124723002954
  166. Feb 2023
  167. www.biorxiv.org www.biorxiv.org
    YTHDC2 serves a distinct late role in spermatocytes during germ cell differentiation
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      DOI: 10.1101/2023.01.23.525146

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    biorxiv.org/content/10.1101/2023.01.23.525146v1
  168. Jan 2023
  169. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Human metastatic cholangiocarcinoma patient-derived xenografts and tumoroids for preclinical drug evaluation
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      DOI: 10.1158/1078-0432.CCR-22-2551

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    ncbi.nlm.nih.gov/pmc/articles/PMC9873249/
  170. www.sciencedirect.com www.sciencedirect.com
    SUMOylation of HNRNPA2B1 modulates RPA dynamics during unperturbed replication and genotoxic stress responses
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    sciencedirect.com/science/article/pii/S1097276523000035
  171. www.sciencedirect.com www.sciencedirect.com
    Oxidized mC modulates synthetic lethality to PARP inhibitors for the treatment of leukemia
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    sciencedirect.com/science/article/pii/S2211124723000384
  172. www.sciencedirect.com www.sciencedirect.com
    Cyclin E-induced replicative stress drives p53-dependent whole-genome duplication
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      DOI: 10.1016/j.cell.2022.12.036

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    sciencedirect.com/science/article/pii/S0092867422015793
  173. www.mdpi.com www.mdpi.com
    Remarkable Synergy When Combining EZH2 Inhibitors with YM155 Is H3K27me3-Independent
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      DOI: 10.3390/cancers15010208

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    mdpi.com/2072-6694/15/1/208
  174. www.sciencedirect.com www.sciencedirect.com
    ATM suppresses c-Myc overexpression in the mammary epithelium in response to estrogen
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    sciencedirect.com/science/article/pii/S2211124722018083
  175. Dec 2022
  176. www.sciencedirect.com www.sciencedirect.com
    The ADP-ribose hydrolase NUDT5 is important for DNA repair
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      DOI: 10.1016/j.celrep.2022.111866

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    sciencedirect.com/science/article/pii/S2211124722017624