661 Matching Annotations
  1. Jul 2023
  2. 52.53.155.43 52.53.155.43
    cd-22-0411-html.html
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    1. scibot 01 Jul 2023
      RRID:AB_10622025

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  3. www.sciencedirect.com www.sciencedirect.com
    Generation of host-directed and virus-specific antivirals using targeted protein degradation promoted by small molecules and viral RNA mimics
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    1. scibot 01 Jul 2023
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      DOI: 10.1016/j.chom.2023.05.030

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    sciencedirect.com/science/article/pii/S1931312823002238
  4. Jun 2023
  5. www.sciencedirect.com www.sciencedirect.com
    Increased G3BP2-Tau interaction in tauopathies is a natural defense against Tau aggregation
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    1. scibot 29 Jun 2023
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      DOI: 10.1016/j.neuron.2023.05.033

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    sciencedirect.com/science/article/pii/S0896627323004348
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    An EZH2-NF-κB Regulatory Axis Drives Expression of Pro-Oncogenic Gene Signatures in Triple Negative Breast Cancer
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    1. scibot 27 Jun 2023
      RRID:AB_10622025

      DOI: 10.1016/j.isci.2023.107115

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    sciencedirect.com/science/article/pii/S2589004223011926
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    Acetate controls endothelial-to-mesenchymal transition
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    1. scibot 21 Jun 2023
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    sciencedirect.com/science/article/pii/S1550413123002036
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    Excess pancreatic elastase alters acinar-β cell communication by impairing the mechano-signaling and the PAR2 pathways
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    1. scibot 21 Jun 2023
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      DOI: 10.1016/j.cmet.2023.05.007

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    sciencedirect.com/science/article/pii/S1550413123001845
  9. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CDT1 inhibits CMG helicase in early S phase to separate origin licensing from DNA synthesis
    1
    1. scibot 17 Jun 2023
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      DOI: 10.1016/j.molcel.2022.12.004

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    ncbi.nlm.nih.gov/pmc/articles/PMC7614657/
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    An Epstein-Barr virus protein interaction map reveals NLRP3 inflammasome evasion via MAVS UFMylation
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    1. scibot 16 Jun 2023
      AB_10622025

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    sciencedirect.com/science/article/pii/S109727652300374X
  11. 52.53.155.43 52.53.155.43
    BPS Publications
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    1. scibot 15 Jun 2023
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      DOI: 10.1111/bph.16156

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    52.53.155.43/a7694b32aeeb75586321cd0d6d28b4685219f279/British J Pharmacology - 2023 - Chen - Emodin promotes hepatic stellate cell senescence and alleviates liver fibrosis via-html.html
  12. 52.53.155.43 52.53.155.43
    Endothelial MRs mediate Western diet-induced lipid disorders and skeletal muscle insulin resistance in females
    1
    1. scibot 15 Jun 2023
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      DOI: 10.1210/endocr/bqad091

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  13. onlinelibrary.wiley.com onlinelibrary.wiley.com
    METTL14 is decreased and regulates m6A modification of α-synuclein in Parkinson's disease
    1
    1. scibot 15 Jun 2023
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      DOI: 10.1111/jnc.15882

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    onlinelibrary.wiley.com/doi/10.1111/jnc.15882
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    New scaffolds for type II JAK2 inhibitors overcome the acquired G993A resistance mutation
    1
    1. scibot 08 Jun 2023
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    sciencedirect.com/science/article/pii/S2451945623001502
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    Reduced acetylation of TFAM promotes bioenergetic dysfunction in the failing heart
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    1. scibot 03 Jun 2023
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      DOI: 10.1016/j.isci.2023.106942

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    sciencedirect.com/science/article/pii/S2589004223010192
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    Rapid adaptation to CDK2 inhibition exposes intrinsic cell-cycle plasticity
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    1. scibot 02 Jun 2023
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      DOI: 10.1016/j.cell.2023.05.013

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    sciencedirect.com/science/article/pii/S0092867423005329
  17. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Ca2+-dependent activator protein for secretion 1 promotes spontaneous recovery in ischemic stroke by regulating BDNF secretion
    1
    1. scibot 01 Jun 2023
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      DOI: 10.1111/jnc.15808

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  18. May 2023
  19. www.sciencedirect.com www.sciencedirect.com
    IL-1β-associated NNT acetylation orchestrates iron-sulfur cluster maintenance and cancer immunotherapy resistance
    1
    1. scibot 31 May 2023
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      DOI: 10.1016/j.molcel.2023.05.011

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    sciencedirect.com/science/article/pii/S1097276523003350
  20. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Reprogramming of Iron Metabolism Confers Ferroptosis Resistance in ECM-Detached Cells
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    1. scibot 27 May 2023
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      DOI: 10.1016/j.isci.2023.106827

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    ncbi.nlm.nih.gov/pmc/articles/PMC10209538/
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    Depletion of CUL4B in macrophages ameliorates diabetic kidney disease via miR-194-5p/ITGA9 axis
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    1. scibot 24 May 2023
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      DOI: 10.1016/j.celrep.2023.112550

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    sciencedirect.com/science/article/pii/S2211124723005612
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    ATROPHIC REMODELING OF THE HEART DURING VITAMIN D DEFICIENCY AND INSUFFICIENCY IN A RAT MODEL
    1
    1. scibot 20 May 2023
      RRID:AB_10622025

      DOI: 10.1016/j.jnutbio.2023.109382

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    sciencedirect.com/science/article/pii/S0955286323001158
  23. link.springer.com link.springer.com
    Liver-specific overexpression of HKDC1 increases hepatocyte size and proliferative capacity
    1
    1. scibot 18 May 2023
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      DOI: 10.1038/s41598-023-33924-3

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    link.springer.com/article/10.1038/s41598-023-33924-3
  24. www.science.org www.science.org
    Deficiency in mammalian STN1 promotes colon cancer development via inhibiting DNA repair
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    1. scibot 18 May 2023
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      DOI: 10.1126/sciadv.add8023

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    science.org/doi/10.1126/sciadv.add8023
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    MicroRNA-31 induced by Fusobacterium nucleatum infection promotes colorectal cancer tumorigenesis
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    1. scibot 18 May 2023
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      DOI: 10.1016/j.isci.2023.106770

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    sciencedirect.com/science/article/pii/S2589004223008477
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    Heat promotes melanogenesis by increasing the paracrine effects in keratinocytes via the TRPV3/Ca2+/Hh signaling pathway
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      DOI: 10.1016/j.isci.2023.106749

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    sciencedirect.com/science/article/pii/S258900422300826X
  27. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Deficiency in mammalian STN1 promotes colon cancer development via inhibiting DNA repair
    1
    1. scibot 12 May 2023
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      DOI: 10.1126/sciadv.add8023

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    ncbi.nlm.nih.gov/pmc/articles/PMC10171824/
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    Vitamin K-dependent carboxylation regulates Ca2+ flux and adaptation to metabolic stress in β cells
    1
    1. scibot 12 May 2023
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      DOI: 10.1016/j.celrep.2023.112500

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    sciencedirect.com/science/article/pii/S2211124723005119
  29. 52.53.155.43 52.53.155.43
    Opioid growth factor receptor promotes adipose tissue thermogenesis via enhancing lipid oxidation
    1
    1. scibot 11 May 2023
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      DOI: 10.1093/lifemeta/load018

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    52.53.155.43/114e5b064461e16a4c14e5a8e7760094e7597154/load018-html.html
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    A nanotherapeutic strategy that engages cytotoxic and immunosuppressive activities for the treatment of cancer recurrence following organ transplantation
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    1. scibot 10 May 2023
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      DOI: 10.1016/j.ebiom.2023.104594

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    sciencedirect.com/science/article/pii/S2352396423001597
  31. www.sciencedirect.com www.sciencedirect.com
    The ubiquitin-ligase TRAF6 and TGFβ type I receptor form a complex with Aurora kinase B contributing to mitotic progression and cytokinesis in cancer cells
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      DOI: 10.1016/j.ebiom.2022.104155

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    sciencedirect.com/science/article/pii/S235239642200336X
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    Exercise-derived peptide protects against pathological cardiac remodeling
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    1. scibot 05 May 2023
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      DOI: 10.1016/j.ebiom.2022.104164

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    sciencedirect.com/science/article/pii/S2352396422003450
  33. Apr 2023
  34. www.sciencedirect.com www.sciencedirect.com
    ZFP36-mediated mRNA decay regulates metabolism
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      DOI: 10.1016/j.celrep.2023.112411

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    sciencedirect.com/science/article/pii/S2211124723004229
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    Mitochondrial dynamics define muscle fiber type by modulating cellular metabolic pathways
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      DOI: 10.1016/j.celrep.2023.112434

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    sciencedirect.com/science/article/pii/S221112472300445X
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    AKT activity orchestrates marginal zone B cell development in mice and humans
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      DOI: 10.1016/j.celrep.2023.112378

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    sciencedirect.com/science/article/pii/S2211124723003893
  37. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mitoxantrone and Mitoxantrone-Loaded Iron Oxide Nanoparticles Induce Cell Death in Human Pancreatic Ductal Adenocarcinoma Cell Spheroids
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      DOI: 10.3390/ma16072906

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    ncbi.nlm.nih.gov/pmc/articles/PMC10096321/
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    Stem cell competition driven by the Axin2-p53 axis controls brain size during murine development
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      DOI: 10.1016/j.devcel.2023.03.016

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    sciencedirect.com/science/article/pii/S1534580723001326
  39. link.springer.com link.springer.com
    N,N-Dimethyl-3β-hydroxycholenamide attenuates neuronal death and retinal inflammation in retinal ischemia/reperfusion injury by inhibiting Ninjurin 1
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      DOI: 10.1186/s12974-023-02754-5

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    link.springer.com/article/10.1186/s12974-023-02754-5
  40. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Adiponectin-mediated promotion of CD44 suppresses diabetic vascular inflammatory effects
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      DOI: 10.1016/j.isci.2023.106428

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    ncbi.nlm.nih.gov/pmc/articles/PMC10067764/
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    Harnessing matrix stiffness to engineer a bone marrow niche for hematopoietic stem cell rejuvenation
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      DOI: 10.1016/j.stem.2023.03.005

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    sciencedirect.com/science/article/pii/S1934590923000760
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    Targeting protein tyrosine phosphatases for CDK6-induced immunotherapy resistance
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      DOI: 10.1016/j.celrep.2023.112314

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    sciencedirect.com/science/article/pii/S221112472300325X
  43. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Phosphate Depletion in Insulin-Insensitive Skeletal Muscle Drives AMPD Activation and Sarcopenia in Chronic Kidney DIsease
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      DOI: 10.1016/j.isci.2023.106355

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  44. Mar 2023
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    Neofunctionalisation of ciliary BBS proteins to nuclear roles is likely a frequent innovation across eukaryotes
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    The ubiquitin E3 ligase TRIM10 promotes STING aggregation and activation in the Golgi apparatus
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    Celastrol directly binds with VAMP7 and RAB7 to inhibit autophagy and induce apoptosis in preadipocytes
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    MFN1 augmentation prevents retinal degeneration in a Charcot-Marie-Tooth type 2A mouse model
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    VE-822 upregulates the deubiquitinase OTUD1 to stabilize FHL1 to inhibit the progression of lung adenocarcinoma
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    Inhibiting tau protein improves the recovery of spinal cord ... : Neural Regeneration Research
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    Phosphomimetics at Ser199/Ser202/Thr205 in Tau Impairs Axonal Transport in Rat Hippocampal Neurons
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    Coumarin-derived imino sulfonate 5h ameliorates cardiac injury induced by myocardial infarction via activating the Sirt1/Nrf2 signaling pathway
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    HRS regulates small extracellular vesicle PD-L1 secretion and is associated with anti-PD-1 treatment efficacy
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    HMGB1/GPC3 dual targeting vaccine induces dendritic cells-mediated CD8+T cell immune response and elicits potential therapeutic effect in hepatocellular carcinoma
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    CD70 is a therapeutic target upregulated in EMT-associated EGFR tyrosine kinase inhibitor resistance
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    Neuroprotective Effects of a Multi-Herbal Extract on Axonal and Synaptic Disruption in Vitro and Cognitive Impairment in Vivo
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    Asparagine and Glutamine Deprivation Alters Ionizing Radiation Response, Migration and Adhesion of a p53null Colorectal Cancer Cell Line
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    Prolonged hypernutrition impairs TREM2-dependent efferocytosis to license chronic liver inflammation and NASH development
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    Pyruvate kinase M2 mediates IL-17 signaling in keratinocytes driving psoriatic skin inflammation
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    Anlotinib Suppressed Ovarian Cancer Progression via Inducing G2/M Phase Arrest and Apoptosis
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    Transcriptomic profiling reveals sex-specific molecular signatures of adipose endothelial cells under obesogenic conditions
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    Identification of Genes Associated with Liver Metastasis in Pancreatic Cancer Reveals PCSK6 as a Crucial Mediator
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    Structurally distinct PARP7 inhibitors provide new insights into the function of PARP7 in regulating nucleic acid-sensing and IFN-β signaling
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    Extensive preclinical validation of combined RMC-4550 and LY3214996 supports clinical investigation for KRAS mutant pancreatic cancer
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    The oncogenic fusion protein DNAJB1-PRKACA can be specifically targeted by peptide-based immunotherapy in fibrolamellar hepatocellular carcinoma
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    Pathophysiological levels of GDF11 activate Smad2/Smad3 signaling and induce muscle atrophy in human iPSC-derived myocytes
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    Depletion of BATF in CAR-T cells enhances antitumor activity by inducing resistance against exhaustion and formation of central memory cells
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    Long non-coding RNA EVADR induced by Fusobacterium nucleatum infection promotes colorectal cancer metastasis
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    Aberrant expression and subcellular localization of ECT2 drives colorectal cancer progression and growth
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  130. Jun 2022
  131. 52.53.155.43 52.53.155.43
    Loss of low molecular weight protein tyrosine phosphatase (LMPTP) shows limited improvement in glucose tolerance but causes mild cardiac hypertrophy in mice
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  132. journals.physiology.org journals.physiology.org
    Loss of low-molecular-weight protein tyrosine phosphatase shows limited improvement in glucose tolerance but causes mild cardiac hypertrophy in mice
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    Ym1+ macrophages orchestrate fibrosis, lesion growth and progression during development of murine pancreatic cancer
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    NR2F1 is a barrier to dissemination of early stage breast cancer cells.
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    Signaling pathways involved in NMDA-induced suppression of M-channels in corticotropin-releasing hormone neurons in central amygdala
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    Jumonji domain-containing protein-3 (JMJD3/Kdm6b) is critical for normal ovarian function and female fertility
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    Elevated levels of follicular fatty acids induce ovarian inflammation via ERK1/2 and inflammasome activation in PCOS
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  138. May 2022
  139. www.jneurosci.org www.jneurosci.org
    Evolution Increases Primates Brain Complexity Extending RbFOX1 Splicing Activity to LSD1 Modulation
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    Ym1+ macrophages orchestrate fibrosis, lesion growth and progression during development of murine pancreatic cancer
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  141. Apr 2022
  142. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Downregulation of microRNA-124-3p promotes subventricular zone neural stem cell activation by enhancing the function of BDNF downstream pathways after traumatic brain injury in adult rats
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    Liquid phase separation of NEMO induced by polyubiquitin chains activates NF-κB
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    L3MBTL2-mediated CGA transcriptional suppression promotes pancreatic cancer progression through modulating autophagy
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    Augmenting NK cell-based immunotherapy by targeting mitochondrial apoptosis
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    VAP-A and its binding partner CERT drive biogenesis of RNA-containing extracellular vesicles at ER membrane contact sites
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  148. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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  149. Mar 2022
  150. link.springer.com link.springer.com
    Ebselen prevents cigarette smoke-induced cognitive dysfunction in mice by preserving hippocampal synaptophysin expression
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    Neutral ceramidase-dependent regulation of macrophage metabolism directs intestinal immune homeostasis and controls enteric infection
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    Indirubin-3’-monoxime acts as proteasome inhibitor: Therapeutic application in multiple myeloma
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    Neddylation is essential for β-catenin degradation in Wnt signaling pathway
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    Regulation of mitochondrial fission by GIPC-mediated Drp1 retrograde transport
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    AXL targeting restores PD-1 blockade sensitivity of STK11/LKB1 mutant NSCLC through expansion of TCF1+ CD8 T cells
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    Methylene-bridge tryptophan fatty acylation regulates PI3K-AKT signaling and glucose uptake
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    Epstein-Barr virus BNRF1 destabilizes SMC5/6 cohesin complexes to evade its restriction of replication compartments
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    K48/K63-linked polyubiquitination of ATG9A by TRAF6 E3 ligase regulates oxidative stress-induced autophagy
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    Cytidine Deaminase APOBEC3A Regulates PD-L1 Expression in Cancer Cells in a JNK/c-JUN-dependent Manner
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  162. Feb 2022
  163. www.sciencedirect.com www.sciencedirect.com
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    Enzymatic activity of glycosyltransferase GLT8D1 promotes human glioblastoma cell migration
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    Hypermethylation of miR-145 promoter-mediated SOX9-CLDN8 pathway regulates intestinal mucosal barrier in Crohn's disease
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    Liquidambaric acid inhibits Wnt/β-catenin signaling and colon cancer via targeting TNF receptor-associated factor 2
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  171. Jan 2022
  172. www.molbiolcell.org www.molbiolcell.org
    Regulation of mitochondrial fission by GIPC-mediated Drp1 retrograde transport
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  173. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CRISPR-Cas9 Screen Identifies DYRK1A as a Target for Radiotherapy Sensitization in Pancreatic Cancer
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  174. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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  178. Dec 2021
  179. cancerimmunolres.aacrjournals.org cancerimmunolres.aacrjournals.org
    The Fibronectin–ILT3 Interaction Functions as a Stromal Checkpoint that Suppresses Myeloid Cells
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    Multiomic analysis identifies CPT1A as a potential therapeutic target in platinum-refractory, high-grade serous ovarian cancer
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    PDIA3 inhibits mitochondrial respiratory function in brain endothelial cells and C. elegans through STAT3 signaling and decreases survival after OGD
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    KDM6B promotes activation of the oncogenic CDK4/6-pRB-E2F pathway by maintaining enhancer activity in MYCN-amplified neuroblastoma
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    Low-intensity pulsed ultrasound-generated singlet oxygen induces telomere damage leading to glioma stem cell awakening from quiescence
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  189. Nov 2021
  190. academic.oup.com academic.oup.com
    Maternal iron deficiency alters trophoblast differentiation and placental development in rat pregnancy
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    Integrated genomic and proteomic analyses identify stimulus-dependent molecular changes associated with distinct modes of skeletal muscle atrophy
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  199. Oct 2021
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    Increased ACTL6A occupancy within mSWI/SNF chromatin remodelers drives human squamous cell carcinoma
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    Pantoprazole ameliorates liver fibrosis and suppresses hepatic stellate cell activation in bile duct ligation rats by promoting YAP degradation
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    The thermogenic activity of adjacent adipocytes fuels the progression of ccRCC and compromises anti-tumor therapeutic efficacy
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    1. scibot 11 Sep 2021
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      DOI: 10.1016/j.cmet.2021.08.012

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    Germline DDX41 mutations cause ineffective hematopoiesis and myelodysplasia
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    1. scibot 03 Sep 2021
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      DOI: 10.1016/j.stem.2021.08.004

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    A NSD3-targeted PROTAC suppresses NSD3 and cMyc oncogenic nodes in cancer cells
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    1. scibot 01 Sep 2021
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      DOI: 10.1016/j.chembiol.2021.08.004

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  219. Aug 2021
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    Cytidine acetylation yields a hypoinflammatory synthetic messenger RNA
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    1. scibot 26 Aug 2021
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      DOI: 10.1016/j.chembiol.2021.07.003

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    A histone modifier, ASXL1, interacts with NONO and is involved in paraspeckle formation in hematopoietic cells
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    1. scibot 25 Aug 2021
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      DOI: 10.1016/j.celrep.2021.109576

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