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Dynamic S-acylation of IDH2 regulates mitochondrial redox homeostasis

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  DOI: 10.1016/j.celrep.2026.117876
  
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sciencedirect.com/science/article/pii/S221112472600954X
Aug 2026
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METTL3 promotes cell-cycle progression via activation of transcriptional elongation

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  DOI: 10.1016/j.molcel.2026.07.011
  
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sciencedirect.com/science/article/pii/S1097276526004971
Jul 2026
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A Pholidota chinensis-derived dihydrophenanthrene acts as a bioactive constituent to trigger GPx4-mediated ferroptosis in colorectal cancer

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1. scibot 07 Jul 2026
  
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  DOI: 10.1016/j.jep.2026.122154
  
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sciencedirect.com/science/article/pii/S0378874126010081
Apr 2026
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Structural basis for ADAM17 activation by the iRhom1 pseudoprotease

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1. scibot 24 Apr 2026
  
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  DOI: 10.1016/j.celrep.2026.117309
  
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sciencedirect.com/science/article/pii/S2211124726003876
Dec 2025
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Oxytocin treatment reduces cancer cachexia in a pre-clinical model

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sciencedirect.com:5037/science/article/pii/S0753332225010194
Nov 2025
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The ER thioredoxin-related transmembrane protein TMX2 controls redox-mediated tethering of ER-mitochondria contacts

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1. scibot 01 Nov 2025
  
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sciencedirect.com/science/article/pii/S2211124725012574
Jun 2025
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Blocking the functional domain of cancer cell surface TIP1 upregulates Midkine via the β-catenin/Wnt signaling pathway

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1. scibot 18 Jun 2025
  
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  DOI: 10.1038/s41417-025-00922-8
  
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nature.com/articles/s41417-025-00922-8
Mar 2025
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Lipoylation inhibition enhances radiation control of lung cancer by suppressing homologous recombination DNA damage repair

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1. scibot 14 Mar 2025
  
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  DOI: 10.1126/sciadv.adt1241
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11900879/
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Bi-allelic LAMP3 variants in childhood interstitial lung disease: a surfactant-related disease

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1. scibot 05 Mar 2025
  
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  DOI: 10.1016/j.ebiom.2025.105626
  
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thelancet.com/journals/ebiom/article/PIIS2352-3964(25)00070-2/abstract
Jan 2025
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Cdk6’s functions are critically regulated by its unique C-terminus

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1. scibot 30 Jan 2025
  
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  DOI: 10.1016/j.isci.2024.111697
  
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sciencedirect.com/science/article/pii/S2589004224029249
Nov 2024
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Itaconate transporter SLC13A3 impairs tumor immunity via endowing ferroptosis resistance

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1. scibot 11 Nov 2024
  
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  DOI: 10.1016/j.ccell.2024.10.010
  
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sciencedirect.com/science/article/pii/S1535610824003982
Sep 2024
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Stanniocalcin 1 is a phagocytosis checkpoint driving tumor immune resistance

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1. scibot 25 Sep 2024
  
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  DOI: 10.1016/j.ccell.2020.12.023
  
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sciencedirect.com/science/article/pii/S1535610820306711
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Mitochondria and Peroxisome Remodeling across Cytomegalovirus Infection Time Viewed through the Lens of Inter-ViSTA

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1. scibot 25 Sep 2024
  
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  DOI: 10.1016/j.celrep.2020.107943
  
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sciencedirect.com/science/article/pii/S2211124720309244
May 2024
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N-Benzylated 5-Hydroxybenzothiophene-2-carboxamides as Multi-Targeted Clk/Dyrk Inhibitors and Potential Anticancer Agents

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1. scibot 31 May 2024
  
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  DOI: 10.3390/cancers16112033
  
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mdpi.com/2072-6694/16/11/2033
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ol_28_1_14449_PDF-html.html

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1. scibot 17 May 2024
  
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  DOI: 10.3892/ol.2024.14449
  
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52.53.155.43/917364cd3fceb398a38ff7cf2bbe2411971526ce/ol_28_1_14449_PDF-html.html
elifesciences.org elifesciences.org

Ribosome subunit attrition and activation of the p53–MDM4 axis dominate the response of MLL-rearranged cancer cells to WDR5 WIN site inhibition

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1. scibot 03 May 2024
  
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  DOI: 10.7554/eLife.90683
  
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elifesciences.org/articles/90683
Apr 2024
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Membrane-bound O-acyltransferase 7 (MBOAT7) shapes lysosomal lipid homeostasis and function to control alcohol-associated liver injury

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1. scibot 24 Apr 2024
  
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  DOI: 10.7554/eLife.92243
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11034944/
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Heterogeneity of tethered agonist signaling in adhesion G protein-coupled receptors

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1. scibot 12 Apr 2024
  
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  DOI: 10.1016/j.chembiol.2024.03.004
  
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sciencedirect.com/science/article/pii/S245194562400120X
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A light-controlled phospholipase C for imaging of lipid dynamics and controlling neural plasticity

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1. scibot 09 Apr 2024
  
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  DOI: 10.1016/j.chembiol.2024.03.001
  
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sciencedirect.com/science/article/pii/S2451945624000904
Dec 2023
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Casein kinase-2 inhibition promotes retinal ganglion cell survival after acute intraocular pressure elevation

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1. scibot 28 Dec 2023
  
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  DOI: 10.4103/1673-5374.385310
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10749609/
Sep 2023
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In vivo modeling of CLL transformation to Richter’s syndrome reveals convergent evolutionary paths and therapeutic vulnerabilities

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  DOI: 10.1158/2643-3230.BCD-22-0082
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9975769/
May 2023
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Acetyl-CoA carboxylase 1 is a suppressor of the adipocyte thermogenic program

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1. scibot 10 May 2023
  
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  DOI: 10.1016/j.celrep.2023.112488
  
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sciencedirect.com/science/article/pii/S2211124723004990
Mar 2023
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Iron overload facilitates neonatal hypoxic-ischemic brain damage via SLC7A11-mediated ferroptosis

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1. scibot 24 Mar 2023
  
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  DOI: 10.1002/jnr.25184
  
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pubmed.ncbi.nlm.nih.gov/36929608/
Feb 2023
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bcd-22-0082-html.html

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52.53.155.43/479e0586fccc84d0ed0a91d33d7fb0443934a0b7/bcd-22-0082-html.html
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Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity

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1. scibot 03 Feb 2023
  
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  DOI: 10.1016/j.molcel.2023.01.015
  
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sciencedirect.com/science/article/pii/S1097276523000382
Jan 2023
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PTEN inhibitor bisperoxovanadium protects against... : Neural Regeneration Research

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1. scibot 19 Jan 2023
  
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  DOI: 10.4103/1673-5374.358606
  
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journals.lww.com/nrronline/Fulltext/2023/07000/PTEN_inhibitor_bisperoxovanadium_protects_against.36.aspx
Nov 2022
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Atypical E3 ligase ZFP91 promotes small-molecule-induced E2F2 transcription factor degradation for cancer therapy

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  DOI: 10.1016/j.ebiom.2022.104353
  
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sciencedirect.com/science/article/pii/S2352396422005357
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Lipopolysaccharide induces placental mitochondrial dysfunction in murine and human systems by reducing MNRR1 levels via a TLR4-independent pathway

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  DOI: 10.1016/j.isci.2022.105342
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9633742/
Sep 2022
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Stimulation of Akt Phosphorylation and Glucose Transport by Metalloporphyrins with Peroxynitrite Decomposition Catalytic Activity

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1. scibot 16 Sep 2022
  
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  DOI: 10.3390/catal12080849
  
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mdpi.com/2073-4344/12/8/849
Jun 2022
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Sensitization of FOLFOX-resistant colorectal cancer cells via the modulation of a novel pathway involving protein phosphatase 2A

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  DOI: 10.1016/j.isci.2022.104518
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9218363/
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Neuregulin-1/ErbB4 signaling modulate Plasmodium falciparum HRP2-induced damage to brain cortical organoids

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  DOI: 10.1016/j.isci.2022.104407
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9157207/
May 2022
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Activity of Estrogen Receptor β Agonists in Therapy-Resistant Estrogen Receptor-Positive Breast Cancer

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1. scibot 18 May 2022
  
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  DOI: 10.3389/fonc.2022.857590
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9097292/
Apr 2022
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Heat-induced SIRT1-mediated H4K16ac deacetylation impairs resection and SMARCAD1 recruitment to double strand breaks

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1. scibot 08 Apr 2022
  
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  DOI: 10.1016/j.isci.2022.104142
  
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sciencedirect.com/science/article/pii/S2589004222004126
Mar 2022
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BPS Publications

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1. scibot 02 Mar 2022
  
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  DOI: 10.1111/bph.15776
  
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Adipocyte-Specific Inhibition of Mir221/222 Ameliorates Diet-Induced Obesity Through Targeting Ddit4

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RhoA within myofibers controls satellite cell microenvironment to allow hypertrophic growth

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Gene-specific quantification of nascent transcription following targeted degradation of endogenous proteins in cultured cells

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Analysis of Il36a induction by C/EBPβ via a half-CRE•C/EBP element in murine macrophages in dependence of its CpG methylation level

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Topoisomerase I inhibition and peripheral nerve injury induce DNA breaks and ATF3-associated axon regeneration in sensory neurons

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Rack1 is essential for corticogenesis by preventing p21-dependent senescence in neural stem cells

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Global mapping of Salmonella enterica-host protein-protein interactions during infection

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Brain endothelial PTEN/AKT/NEDD4-2/MFSD2A axis regulates blood-brain barrier permeability

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EXO5-DNA structure and BLM interactions direct DNA resection critical for ATR-dependent replication restart

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NOTCH3-targeted antibody drug conjugates regress tumors by inducing apoptosis in receptor cells and through transendocytosis into ligand cells

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Hydroxychloroquine Inhibits Macrophage Activation and Attenuates Renal Fibrosis After Ischemia-Reperfusion Injury

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Proteomics reveals distinct mechanisms regulating the release of cytokines and alarmins during pyroptosis

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Integrin αvβ6–TGFβ–SOX4 Pathway Drives Immune Evasion in Triple-Negative Breast Cancer

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Streptococcus suis Induces Expression of Cyclooxygenase-2 in Porcine Lung Tissue

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Impact of WIN site inhibitor on the WDR5 interactome

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MYC regulates ribosome biogenesis and mitochondrial gene expression programs through its interaction with host cell factor–1

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  DOI: 10.7554/eLife.60191
  
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Multi-color Molecular Visualization of Signaling Proteins Reveals How C-Terminal Src Kinase Nanoclusters Regulate T Cell Receptor Activation

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Generation of a MCPH1 knockout human embryonic stem cell line by CRISPR/Cas9 technology

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A dynamic interaction between CD19 and the tetraspanin CD81 controls B cell co-receptor trafficking

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L ARP7 Is a BRCA1 Ubiquitinase Substrate and Regulates Genome Stability and Tumorigenesis

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The exogenous natural phospholipids, EPA-PC and EPA-PE, contributes to ameliorate inflammation and promote macrophages polarization

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Quantitative and Dynamic Catalogs of Proteins Released during Apoptotic and Necroptotic Cell Death

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Mitochondrial fatty acid synthesis coordinates oxidative metabolism in mammalian mitochondria

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Control of Early B Cell Development by the RNA N6-Methyladenosine Methylation

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GDE2-Dependent Activation of Canonical Wnt Signaling in Neurons Regulates Oligodendrocyte Maturation

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Loss of aryl hydrocarbon receptor potentiates FoxM1 signaling to enhance self‐renewal of colonic stem and progenitor cells

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Obesity-linked suppression of membrane-bound O-acyltransferase 7 (MBOAT7) drives non-alcoholic fatty liver disease

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Untitled document

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FANCA Promotes DNA Double-Strand Break Repair by Catalyzing Single-Strand Annealing and Strand Exchange

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Acetyl-CoA Carboxylase 1-Dependent Protein Acetylation Controls Breast Cancer Metastasis and Recurrence

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p53 Modulates the Fate of Cardiac Progenitor Cells Ex Vivo and in the Diabetic Heart In Vivo

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