700 Matching Annotations
  1. Feb 2024
  2. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    RNA Helicase DDX3 Regulates RAD51 Localization and DNA Damage Repair in Ewing Sarcoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC10844834/
  3. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Alleviation of monocyte exhaustion by BCG derivative mycolic acid
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    ncbi.nlm.nih.gov/pmc/articles/PMC10845070/
  4. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Osimertinib covalently binds to CD34 and eliminates myeloid leukemia stem/progenitor cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC10831336/
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    Streptococcus anginosus promotes gastric inflammation, atrophy, and tumorigenesis in mice
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    cell.com/cell/fulltext/S0092-8674(24)00006-0
  6. Jan 2024
  7. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    circGlis3 promotes β-cell dysfunction by inhibiting hnRNPF nuclear translocation and encoding Glis3-348aa protein
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    ncbi.nlm.nih.gov/pmc/articles/PMC10788204/
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    The mitochondrial genome-encoded peptide MOTS-c interacts with Bcl-2 to alleviate nonalcoholic steatohepatitis progression
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    sciencedirect.com/science/article/pii/S2211124723015991
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    A GAPDH serotonylation system couples CD8+ T cell glycolytic metabolism to antitumor immunity
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    sciencedirect.com/science/article/pii/S1097276523010341
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    A pancreatic cancer organoid platform identifies an inhibitor specific to mutant KRAS
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    sciencedirect.com/science/article/pii/S1934590923004113
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    hRpn13 shapes the proteome and transcriptome through epigenetic factors HDAC8, PADI4, and transcription factor NF-κB p50
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    sciencedirect.com/science/article/pii/S1097276523009802
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    Antitumor efficacy of a sequence-specific DNA-targeted γPNA-based c-Myc inhibitor
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    sciencedirect.com/science/article/pii/S2666379123005712
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    The phosphodiesterase 2A controls lymphatic junctional maturation via cGMP-dependent notch signaling
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    sciencedirect.com/science/article/pii/S1534580723006524
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    The FANCI/FANCD2 complex links DNA damage response to R-loop regulation through SRSF1-mediated mRNA export
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    sciencedirect.com/science/article/pii/S2211124723016224
  15. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Bruton’s Tyrosine Kinase Inhibitors With Distinct Binding Modes Reveal Differential Functional Impact on B-Cell Receptor Signaling
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    ncbi.nlm.nih.gov/pmc/articles/PMC10762339/
  16. www.biorxiv.org www.biorxiv.org
    M4-mediated cholinergic transmission is reduced in parkinsonian mice and its restoration alleviates motor deficits and levodopa-induced dyskinesia
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    biorxiv.org/content/10.1101/2023.08.23.554510v1
  17. link.springer.com link.springer.com
    Fasting and fasting-mimicking treatment activate SIRT1/LXRα and alleviate diabetes-induced systemic and microvascular dysfunction
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    link.springer.com/article/10.1007/s00125-021-05431-5
  18. Dec 2023
  19. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Casein kinase-2 inhibition promotes retinal ganglion cell survival after acute intraocular pressure elevation
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    ncbi.nlm.nih.gov/pmc/articles/PMC10749609/
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    Sphingolipid paracrine signaling impairs keratinocyte adhesion to promote melanoma invasion
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    sciencedirect.com/science/article/pii/S221112472301598X
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    ChREBP is activated by reductive stress and mediates GCKR-associated metabolic traits
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    sciencedirect.com/science/article/pii/S1550413123004217
  22. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Nanocurcumin attenuates pyroptosis and inflammation through inhibiting NF-κB/GSDMD signal in high altitude-associated acute liver injury
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    onlinelibrary.wiley.com/doi/10.1002/jbt.23606
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    SYK ubiquitination by CBL E3 ligases restrains cross-presentation of dead cell-associated antigens by type 1 dendritic cells
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    sciencedirect.com/science/article/pii/S2211124723015188
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    mct-22-0642 (1)-html.html
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  25. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mitoguardin 1 and 2 promote granulosa cell proliferation by activating AKT and regulating the Hippo-YAP1 signaling pathway
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    ncbi.nlm.nih.gov/pmc/articles/PMC10682431/
  26. Nov 2023
  27. www.sciencedirect.com www.sciencedirect.com
    In silico analysis and theratyping of an ultra-rare CFTR genotype (W57G/A234D) in primary human rectal and nasal epithelial cells
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    sciencedirect.com/science/article/pii/S2589004223022575
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    Dual stop codon suppression in mammalian cells with genomically integrated genetic code expansion machinery
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    sciencedirect.com/science/article/pii/S2667237523002904
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    Tsc2 coordinates neuroprogenitor differentiation
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    sciencedirect.com/science/article/pii/S2589004223025191
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    HOXC6 drives a therapeutically targetable pancreatic cancer growth and metastasis pathway by regulating MSK1 and PPP2R2B
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    sciencedirect.com/science/article/pii/S2666379123004792
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    Pan-cancer tRNA-derived fragment CAT1 coordinates RBPMS to stabilize NOTCH2 mRNA to promote tumorigenesis
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    sciencedirect.com/science/article/pii/S2211124723014201
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    Hepatic palmitoyl-proteomes and acyl-protein thioesterase protein proximity networks link lipid modification and mitochondria
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    sciencedirect.com/science/article/pii/S2211124723014018
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    A genetic variant of the Wnt receptor LRP6 accelerates synapse degeneration during aging and in Alzheimer’s disease
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    ncbi.nlm.nih.gov/pmc/articles/PMC10624429/
  34. 52.53.155.43 52.53.155.43
    Guanylate Binding Protein 1 (GBP1) modulates proteasomal machinery in ovarian cancer
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    52.53.155.43/53c790045212682105233198a95a2325be657a67/1-s2.0-S2589004223023696-main-html.html
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    The midnolin-proteasome pathway catches proteins for ubiquitination-independent degradation
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    ncbi.nlm.nih.gov/pmc/articles/PMC10617673/
  36. www.science.org www.science.org
    Synaptic BMAL1 phosphorylation controls circadian hippocampal plasticity
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    science.org/doi/10.1126/sciadv.adj1010
  37. www.sciencedirect.com www.sciencedirect.com
    Membrane anchoring of the DIRAS3 N-terminal extension permits tumor suppressor function
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    sciencedirect.com/science/article/pii/S2589004223022289
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    Mast-cell-specific receptor mediates alcohol-withdrawal-associated headache in male mice
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    sciencedirect.com/science/article/abs/pii/S0896627323007523
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    Photoaffinity labeling coupled with proteomics identify PDI-ADAM17 module is targeted by (−)-vinigrol to induce TNFR1 shedding and ameliorate rheumatoid arthritis in mice
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    sciencedirect.com/science/article/abs/pii/S2451945623003392
  40. Oct 2023
  41. www.sciencedirect.com www.sciencedirect.com
    High-throughput chemogenetic drug screening reveals PKC-RhoA/PKN as a targetable signaling vulnerability in GNAQ-driven uveal melanoma
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    sciencedirect.com/science/article/pii/S2666379123004214
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    ZNF692 organizes a hub specialized in 40S ribosomal subunit maturation enhancing translation in rapidly proliferating cells
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    sciencedirect.com/science/article/pii/S2211124723012925
  43. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Synaptic BMAL1 phosphorylation controls circadian hippocampal plasticity
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    ncbi.nlm.nih.gov/pmc/articles/PMC10599629/
  44. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Modification of Lysine-260 2-hydroxyisobutyrylation destabilizes ALDH1A1 expression to regulate bladder cancer progression
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    ncbi.nlm.nih.gov/pmc/articles/PMC10585400/
  45. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Identification of transcriptome characteristics of granulosa cells and the possible role of UBE2C in the pathogenesis of premature ovarian insufficiency
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    ncbi.nlm.nih.gov/pmc/articles/PMC10580542/
  46. www.science.org www.science.org
    The midnolin-proteasome pathway catches proteins for ubiquitination-independent degradation
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    science.org/doi/10.1126/science.adh5021
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    Comprehensive quantification of metabolic flux during acute cold stress in mice
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    sciencedirect.com/science/article/abs/pii/S1550413123003376
  48. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Tyrosine hydroxylase phosphorylation is under the control of serine 40
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    onlinelibrary.wiley.com/doi/full/10.1111/jnc.15963
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    Cancer cells reprogram to metastatic state through the acquisition of platelet mitochondria
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    sciencedirect.com/science/article/pii/S2211124723011592
  50. Sep 2023
  51. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Protocol for high-sensitivity western blot on murine hematopoietic stem cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC10519847/
  52. www.mdpi.com www.mdpi.com
    Generation of Novel Immunocompetent Mouse Cell Lines to Model Experimental Metastasis of High-Risk Neuroblastoma
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    mdpi.com/2072-6694/15/19/4693
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    TGS1/PIMT knockdown reduces lipid accumulation in adipocytes, limits body weight gain and promotes insulin sensitivity in mice
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    sciencedirect.com/science/article/pii/S0925443923002624
  54. 52.53.155.43 52.53.155.43
    Different sensitivity to diet-induced hyperinsulinemia and hyperglycemia between mice with global or bone marrow-specific apoE receptor-2 deficiency
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    52.53.155.43/0ffab27c4a32d9d4b6b052fcf84d29780cb40234/wolfkiel-et-al-2023-different-sensitivity-to-diet-induced-hyperinsulinemia-and-hyperglycemia-between-mice-with-global-html.html
  55. 52.53.155.43 52.53.155.43
    British J Pharmacology - 2023 - Dai-html.html
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    52.53.155.43/8d076c70ed36377d24eb7bc3686db861bc15751d/British J Pharmacology - 2023 - Dai-html.html
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    STING signaling promotes NK cell antitumor immunity and maintains a reservoir of TCF-1+ NK cells
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    sciencedirect.com/science/article/pii/S2211124723011191
  57. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    RLY-4008, the first highly selective FGFR2 inhibitor with activity across FGFR2 alterations and resistance mutations
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    ncbi.nlm.nih.gov/pmc/articles/PMC10481131/
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    Immunoglobulin G inhibits glucocorticoid-induced osteoporosis through occupation of FcγRI
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    sciencedirect.com/science/article/pii/S2589004223018266
  59. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SHOX2 promotes prostate cancer proliferation and metastasis through disruption of the Hippo-YAP pathway
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    ncbi.nlm.nih.gov/pmc/articles/PMC10470409/
  60. Aug 2023
  61. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Regulation of mitotic clonal expansion and thermogenic pathway are involved in the antiadipogenic effects of cyanidin-3-O-glucoside
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    ncbi.nlm.nih.gov/pmc/articles/PMC10442822/
  62. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Activator protein-1 (AP-1) signaling inhibits the growth of Ewing sarcoma cells in response to DNA replication stress
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    ncbi.nlm.nih.gov/pmc/articles/PMC10434289/
  63. 52.53.155.43 52.53.155.43
    Synergy of 5-aminolevulinate supplement and CX3CR1 suppression promotes liver regeneration via elevated IGF-1 signaling
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    52.53.155.43/1bbe45cf5b4e78c7829bbc8558904ff45b580eb3/PIIS2211124723009956-html.html
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    FoxM1 coordinates cell division, protein synthesis, and mitochondrial activity in a subset of β cells during acute metabolic stress
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    sciencedirect.com/science/article/pii/S221112472300997X
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    Hyodeoxycholic acid alleviates non-alcoholic fatty liver disease through modulating the gut-liver axis
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    sciencedirect.com/science/article/pii/S155041312300270X
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    METTL3 drives NAFLD-related hepatocellular carcinoma and is a therapeutic target for boosting immunotherapy
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    sciencedirect.com/science/article/pii/S2666379123002975
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    IL-24 is the key effector of Th9 cell-mediated tumor immunotherapy
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    Genetic ablation of ketohexokinase C isoform impairs pancreatic cancer development
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    ncbi.nlm.nih.gov/pmc/articles/PMC10407955/
  69. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    TPL2 kinase activity regulates microglial inflammatory responses and promotes neurodegeneration in tauopathy mice
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    ncbi.nlm.nih.gov/pmc/articles/PMC10411973/
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    Discovery of a pyrrole-pyridinimidazole derivative as novel SIRT6 inhibitor for sensitizing pancreatic cancer to gemcitabine
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    ncbi.nlm.nih.gov/pmc/articles/PMC10403574/
  73. Jul 2023
  74. www.sciencedirect.com www.sciencedirect.com
    Magneto-mechanical stimulation modulates osteocyte fate via the ECM-integrin-CSK axis and wnt pathway
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    sciencedirect.com/science/article/pii/S2589004223014426
  75. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Epigenetic combined with transcriptomic analysis of the m6A methylome after spared nerve injury-induced neuropathic pain in mice
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    ncbi.nlm.nih.gov/pmc/articles/PMC10360113/
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    Hexokinase 2-mediated gene expression via histone lactylation is required for hepatic stellate cell activation and liver fibrosis
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    sciencedirect.com/science/article/pii/S1550413123002231
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    Targeting phenylpyruvate restrains excessive NLRP3 inflammasome activation and pathological inflammation in diabetic wound healing
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    High FOXA1 levels induce ER transcriptional reprogramming, a pro-metastatic secretome, and metastasis in endocrine-resistant breast cancer
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    Spermine is a natural suppressor of AR signaling in castration-resistant prostate cancer
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    Cancer-associated mesothelial cells are regulated by the anti-Müllerian hormone axis
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  82. www.nature.com www.nature.com
    Kinome-wide CRISPR-Cas9 knockout screens revealed PLK1 as a therapeutic target for osteosarcoma
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    nature.com/articles/s41420-023-01526-7
  83. www.embopress.org www.embopress.org
    Centrosome amplification fine tunes tubulin acetylation to differentially control intracellular organization
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    Cytosolic LPS-induced caspase-11 oligomerization and activation is regulated by extended synaptotagmin 1
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    Levomilnacipran ameliorates lipopolysaccharide-induced depression-like behaviors and suppressed the TLR4/Ras signaling pathway
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    Selective activation of PPARα maintains thermogenic capacity of beige adipocytes
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  87. Jun 2023
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    Glutamine supplementation reverses manganese neurotoxicity by eliciting the mitochondrial unfolded protein response
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  89. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Non-muscle MYH10/myosin IIB recruits ESCRT-III to participate in autophagosome closure to maintain neuronal homeostasis
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    ncbi.nlm.nih.gov/pmc/articles/PMC10283425/
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    Modulation of cellular metabolism by protein crotonylation regulates pancreatic cancer progression
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    sciencedirect.com/science/article/pii/S2211124723006770
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    Identification of an IL-1 receptor mutation driving autoinflammation directs IL-1-targeted drug design
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    sciencedirect.com/science/article/pii/S1074761323002315
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    Altered gut microbiota of obesity subjects promotes colorectal carcinogenesis in mice
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    sciencedirect.com/science/article/pii/S2352396423002359
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    Excess pancreatic elastase alters acinar-β cell communication by impairing the mechano-signaling and the PAR2 pathways
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    sciencedirect.com/science/article/pii/S1550413123001845
  94. aacrjournals.org aacrjournals.org
    (R)-2-hydroxyglutarate inhibits KDM5 histone lysine demethylases to drive transformation in IDH-mutant cancers
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