413 Matching Annotations
  1. May 2022
  2. www.sciencedirect.com www.sciencedirect.com
    Homogeneity of antibody-drug conjugates critically impacts the therapeutic efficacy in brain tumors
    1
    1. scibot 26 May 2022
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      DOI: 10.1016/j.celrep.2022.110839

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    sciencedirect.com/science/article/pii/S221112472200612X
  3. www.sciencedirect.com www.sciencedirect.com
    Postnatal expression of cell cycle promoter Fam64a causes heart dysfunction by inhibiting cardiomyocyte differentiation through repression of Klf15
    1
    1. scibot 19 May 2022
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      DOI: 10.1016/j.isci.2022.104337

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    sciencedirect.com/science/article/pii/S2589004222006083
  4. www.mdpi.com www.mdpi.com
    EMT, Stemness, and Drug Resistance in Biological Context: A 3D Tumor Tissue/In Silico Platform for Analysis of Combinatorial Treatment in NSCLC with Aggressive KRAS-Biomarker Signatures
    1
    1. scibot 10 May 2022
      RRID:AB_302459

      DOI: 10.3390/cancers14092176

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    mdpi.com/2072-6694/14/9/2176
  5. www.sciencedirect.com www.sciencedirect.com
    p57Kip2 imposes the reserve stem cell state of gastric chief cells
    1
    1. scibot 06 May 2022
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      DOI: 10.1016/j.stem.2022.04.001

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    sciencedirect.com/science/article/pii/S1934590922001540
  6. Apr 2022
  7. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Downregulation of microRNA-124-3p promotes subventricular zone neural stem cell activation by enhancing the function of BDNF downstream pathways after traumatic brain injury in adult rats
    1
    1. scibot 30 Apr 2022
      AB_302459

      DOI: 10.1111/cns.13845

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    onlinelibrary.wiley.com/doi/10.1111/cns.13845
  8. academic.oup.com academic.oup.com
    GH action in prostate cancer cells promotes proliferation limits apoptosis and regulates cancer-related gene expression
    1
    1. scibot 29 Apr 2022
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      DOI: 10.1210/endocr/bqac031

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    academic.oup.com/endo/article/163/5/bqac031/6564019
  9. academic.oup.com academic.oup.com
    Immunosuppressive tumor microenvironment in Uterine Serous Carcinoma via CCL7 signal with myeloid-derived suppressor cells
    1
    1. scibot 29 Apr 2022
      RRID:AB_302459

      DOI: 10.1093/carcin/bgac032

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    academic.oup.com/carcin/advance-article/doi/10.1093/carcin/bgac032/6556146
  10. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Transcription factors AP-2α and AP-2β regulate distinct segments of the distal nephron in the mammalian kidney
    1
    1. scibot 29 Apr 2022
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      DOI: 10.1038/s41467-022-29644-3

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    ncbi.nlm.nih.gov/pmc/articles/PMC9038906/
  11. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    BARS Influences Neuronal Development by Regulation of Post-Golgi Trafficking
    1
    1. scibot 27 Apr 2022
      RRID:AB_302459

      DOI: 10.3390/cells11081320

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    ncbi.nlm.nih.gov/pmc/articles/PMC9026897/
  12. www.nature.com www.nature.com
    Identifying a confused cell identity for esophageal squamous cell carcinoma
    1
    1. scibot 23 Apr 2022
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      DOI: 10.1038/s41392-022-00946-8

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    nature.com/articles/s41392-022-00946-8
  13. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    NXN Gene Epigenetic Changes in an Adult Neurogenesis Model of Alzheimer’s Disease
    1
    1. scibot 13 Apr 2022
      RRID:AB_302459

      DOI: 10.3390/cells11071069

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    ncbi.nlm.nih.gov/pmc/articles/PMC8998146/
  14. www.sciencedirect.com www.sciencedirect.com
    Uncompensated mitochondrial oxidative stress underlies heart failure in an iPSC-derived model of congenital heart disease
    1
    1. scibot 08 Apr 2022
      RRID:AB_302459

      DOI: 10.1016/j.stem.2022.03.003

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    sciencedirect.com/science/article/pii/S1934590922001011
  15. www.sciencedirect.com www.sciencedirect.com
    Promoter and enhancer RNAs regulate chromatin reorganization and activation of miR-10b/HOXD locus, and neoplastic transformation in glioma
    1
    1. scibot 07 Apr 2022
      RRID:AB_302459

      DOI: 10.1016/j.molcel.2022.03.018

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    sciencedirect.com/science/article/pii/S1097276522002568
  16. Mar 2022
  17. www.sciencedirect.com www.sciencedirect.com
    NMDA receptor-dependent prostaglandin-endoperoxide synthase 2 induction in neurons promotes glial proliferation during brain development and injury
    1
    1. scibot 30 Mar 2022
      RRID:AB_302459

      DOI: 10.1016/j.celrep.2022.110557

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    sciencedirect.com/science/article/pii/S2211124722003011
  18. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Dormant Nfatc1 reporter-marked basal stem/progenitor cells contribute to mammary lobuloalveoli formation
    1
    1. scibot 23 Mar 2022
      RRID:AB_302459

      DOI: 10.1016/j.isci.2022.103982

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    ncbi.nlm.nih.gov/pmc/articles/PMC8924625/
  19. www.sciencedirect.com www.sciencedirect.com
    Single-cell landscapes of primary glioblastomas and matched explants and cell lines show variable retention of inter- and intratumor heterogeneity
    1
    1. scibot 18 Mar 2022
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      DOI: 10.1016/j.ccell.2022.02.016

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    sciencedirect.com/science/article/pii/S153561082200068X
  20. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Endothelial cells promote the proliferation and migration of Schwann cells
    1
    1. scibot 11 Mar 2022
      RRID:AB_302459

      DOI: 10.21037/atm-22-81

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    ncbi.nlm.nih.gov/pmc/articles/PMC8848405/
  21. www.sciencedirect.com www.sciencedirect.com
    Stem cell differentiation with consistent lineage commitment induced by a flash of ultrafast-laser activation in vitro and in vivo
    1
    1. scibot 09 Mar 2022
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      DOI: 10.1016/j.celrep.2022.110486

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    sciencedirect.com/science/article/pii/S2211124722002194
  22. www.sciencedirect.com www.sciencedirect.com
    Human biliary epithelial cells from discarded donor livers rescue bile duct structure and function in a mouse model of biliary disease
    1
    1. scibot 04 Mar 2022
      RRID:AB_302459

      DOI: 10.1016/j.stem.2022.02.006

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    sciencedirect.com/science/article/pii/S1934590922000571
  23. Feb 2022
  24. www.sciencedirect.com www.sciencedirect.com
    An omic and multidimensional spatial atlas from serial biopsies of an evolving metastatic breast cancer
    1
    1. scibot 16 Feb 2022
      RRID:AB_302459

      DOI: 10.1016/j.xcrm.2022.100525

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    sciencedirect.com/science/article/pii/S2666379122000258
  25. www.embopress.org www.embopress.org
    Identification of treatment-induced vulnerabilities in pancreatic cancer patients using functional model systems
    1
    1. scibot 12 Feb 2022
      RRID:AB_302459

      DOI: 10.15252/emmm.202114876

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    embopress.org/doi/abs/10.15252/emmm.202114876
  26. www.sciencedirect.com www.sciencedirect.com
    Identification of the nucleotide-free state as a therapeutic vulnerability for inhibition of selected oncogenic RAS mutants
    2
    1. scibot 11 Feb 2022
      AB_302459

      DOI: 10.1016/j.celrep.2022.110322

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    2. scibot 09 Feb 2022
      AB_302459

      DOI: 10.1016/j.celrep.2022.110322

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    sciencedirect.com/science/article/pii/S221112472200033X
  27. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Robust temporal changes of cellular senescence and proliferation after sciatic nerve injury
    1
    1. scibot 05 Feb 2022
      AB_302459

      DOI: 10.4103/1673-5374.330619

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    ncbi.nlm.nih.gov/pmc/articles/PMC8771116/
  28. www.sciencedirect.com www.sciencedirect.com
    Development of human alveolar epithelial cell models to study distal lung biology and disease
    1
    1. scibot 04 Feb 2022
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      DOI: 10.1016/j.isci.2022.103780

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    sciencedirect.com/science/article/pii/S2589004222000505
  29. www.sciencedirect.com www.sciencedirect.com
    Inflammatory fibroblasts mediate resistance to neoadjuvant therapy in rectal cancer
    1
    1. scibot 04 Feb 2022
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      DOI: 10.1016/j.ccell.2022.01.004

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    sciencedirect.com/science/article/pii/S153561082200006X
  30. www.sciencedirect.com www.sciencedirect.com
    Histone chaperone FACT complex coordinates with HIF to mediate an expeditious transcription program to adapt to poorly oxygenated cancers
    1
    1. scibot 02 Feb 2022
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      DOI: 10.1016/j.celrep.2022.110304

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    sciencedirect.com/science/article/pii/S221112472200016X
  31. Jan 2022
  32. faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com
    Eukaryotic elongation factor 2 kinase regulates foam cell formation via translation of CD36
    1
    1. scibot 22 Jan 2022
      RRID:AB_302459

      DOI: 10.1096/fj.202101034R

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    faseb.onlinelibrary.wiley.com/doi/10.1096/fj.202101034R
  33. www.sciencedirect.com www.sciencedirect.com
    Limb development genes underlie variation in human fingerprint patterns
    1
    1. scibot 07 Jan 2022
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      DOI: 10.1016/j.cell.2021.12.008

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    sciencedirect.com/science/article/pii/S009286742101446X
  34. Dec 2021
  35. www.sciencedirect.com www.sciencedirect.com
    PAK5 promotes RNA helicase DDX5 sumoylation and miRNA-10b processing in a kinase-dependent manner in breast cancer
    1
    1. scibot 22 Dec 2021
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      DOI: 10.1016/j.celrep.2021.110127

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    sciencedirect.com/science/article/pii/S2211124721016235
  36. www.sciencedirect.com www.sciencedirect.com
    AMP-activated protein kinase alpha1 promotes tumor development via FOXP3 elevation in tumor-infiltrating Treg cells
    1
    1. scibot 21 Dec 2021
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      DOI: 10.1016/j.isci.2021.103570

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    sciencedirect.com/science/article/pii/S2589004221015406
  37. www.sciencedirect.com www.sciencedirect.com
    Low-intensity pulsed ultrasound-generated singlet oxygen induces telomere damage leading to glioma stem cell awakening from quiescence
    1
    1. scibot 18 Dec 2021
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      DOI: 10.1016/j.isci.2021.103558

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    sciencedirect.com/science/article/pii/S2589004221015285
  38. academic.oup.com academic.oup.com
    Regulation of AKT signaling in mouse uterus
    1
    1. scibot 15 Dec 2021
      RRID:AB_302459

      DOI: 10.1210/endocr/bqab233

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    academic.oup.com/endo/article/163/1/bqab233/6430242
  39. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Isoform-specific roles of prolyl hydroxylases in the regulation of pancreatic β-cell function
    1
    1. scibot 11 Dec 2021
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      DOI: 10.1210/endocr/bqab226

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    ncbi.nlm.nih.gov/pmc/articles/PMC8643417/
  40. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A new murine esophageal organoid culture method and organoid-based model of esophageal squamous cell neoplasia
    1
    1. scibot 11 Dec 2021
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      DOI: 10.1016/j.isci.2021.103440

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    ncbi.nlm.nih.gov/pmc/articles/PMC8633967/
  41. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Murine cerebral organoids develop network of functional neurons and hippocampal brain region identity
    1
    1. scibot 11 Dec 2021
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      DOI: 10.1016/j.isci.2021.103438

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    ncbi.nlm.nih.gov/pmc/articles/PMC8640475/
  42. www.sciencedirect.com www.sciencedirect.com
    Mitochondrial complex I inhibitors suppress tumor growth through concomitant acidification of the intra- and extracellular environment
    1
    1. scibot 08 Dec 2021
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      DOI: 10.1016/j.isci.2021.103497

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    sciencedirect.com/science/article/pii/S2589004221014681
  43. www.sciencedirect.com www.sciencedirect.com
    Redox-sensitive cyclophilin A elicits chemoresistance through realigning cellular oxidative status in colorectal cancer
    1
    1. scibot 01 Dec 2021
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      DOI: 10.1016/j.celrep.2021.110069

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    sciencedirect.com/science/article/pii/S2211124721015552
  44. Nov 2021
  45. www.sciencedirect.com www.sciencedirect.com
    Identification of a gut microbiota member that ameliorates DSS-induced colitis in intestinal barrier enhanced Dusp6-deficient mice
    1
    1. scibot 24 Nov 2021
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      DOI: 10.1016/j.celrep.2021.110016

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    sciencedirect.com/science/article/pii/S2211124721014984
  46. www.sciencedirect.com www.sciencedirect.com
    A recurrent chromosomal inversion suffices for driving escape from oncogene-induced senescence via subTAD reorganization
    1
    1. scibot 18 Nov 2021
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      DOI: 10.1016/j.molcel.2021.10.017

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    sciencedirect.com/science/article/pii/S1097276521009096
  47. www.sciencedirect.com www.sciencedirect.com
    Efferocytosis induces macrophage proliferation to help resolve tissue injury
    1
    1. scibot 16 Nov 2021
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      DOI: 10.1016/j.cmet.2021.10.015

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    In vivo monitoring of the therapeutic efficacy of a CXCR1/2 inhibitor with 18F-FDG PET/CT imaging in experimental head and neck carcinoma: A feasibility study
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    H3.3K27M Cooperates with Trp53 Loss and PDGFRA Gain in Mouse Embryonic Neural Progenitor Cells to Induce Invasive High-Grade Gliomas
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    H3.3K27M Cooperates with Trp53 Loss and PDGFRA Gain in Mouse Embryonic Neural Progenitor Cells to Induce Invasive High-Grade Gliomas
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    Roles of vascular endothelial and smooth muscle cells in the vasculoprotective effect of insulin in a mouse model of restenosis - Yusaku Mori, Marel Gonzalez Medina, Zhiwei Liu, June Guo, Luke S Dingwell, Simon Chiang, Carl Ronald Kahn, Mansoor Husain, Adria Giacca, 2021
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  91. Jun 2021
  92. www.sciencedirect.com www.sciencedirect.com
    H3K27 demethylases are dispensable for activation of Polycomb-regulated injury response genes in peripheral nerve.
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  93. May 2021
  94. www.nature.com www.nature.com
    JunB is a key regulator of multiple myeloma bone marrow angiogenesis
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      DOI: 10.1038/s41375-021-01271-9

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  95. www.sciencedirect.com www.sciencedirect.com
    Discrete limbal epithelial stem cell populations mediate corneal homeostasis and wound healing
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  96. www.nature.com www.nature.com
    Loss of Ambra1 promotes melanoma growth and invasion
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  97. academic.oup.com academic.oup.com
    Mammary Tumors Growing in the Absence of Growth Hormone are More Sensitive to Doxorubicin than Wild-type Tumors
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      DOI: 10.1210/endocr/bqab013

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    Ectosomal PKM2 Promotes HCC by Inducing Macrophage Differentiation and Remodeling the Tumor Microenvironment
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    Dek Modulates Global Intron Retention during Muscle Stem Cells Quiescence Exit
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    Algorithmic assessment of cellular senescence in experimental and clinical specimens
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    Obesity-associated hyperleptinemia alters the gliovascular interface of the hypothalamus to promote hypertension
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  102. Apr 2021
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    Promotion of cholangiocarcinoma growth by diverse cancer-associated fibroblast subpopulations
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    An Organoid Biobank of Neuroendocrine Neoplasms Enables Genotype-Phenotype Mapping
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    EPHA2-dependent outcompetition of KRASG12D mutant cells by wild-type neighbors in the adult pancreas
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  106. www.cell.com www.cell.com
    IL6/STAT3 Signaling Hijacks Estrogen Receptor α Enhancers to Drive Breast Cancer Metastasis
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    PKCλ/ι Loss Induces Autophagy, Oxidative Phosphorylation, and NRF2 to Promote Liver Cancer Progression
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    PAF remodels the DREAM complex to bypass cell quiescence and promote lung tumorigenesis
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    Influence of the microenvironment on modulation of the host response by typhoid toxin
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    Macrophages in SHH subgroup medulloblastoma display dynamic heterogeneity that varies with treatment modality
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  111. Mar 2021
  112. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Xenografts derived from patients with head and neck cancer recapitulate patient tumour properties
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  113. www.sciencedirect.com www.sciencedirect.com
    Human gastrointestinal epithelia of the esophagus, stomach, and duodenum resolved at single-cell resolution
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  114. faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com
    Senolytic therapy ameliorates renal fibrosis postacute kidney injury by alleviating renal senescence
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  115. Feb 2021
  116. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Metabolism, Oxidative Stress and Cell Signaling: Mitochondrial-specific autophagy linked to mitochondrial dysfunction following traumatic freeze injury in mice
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      DOI: 10.1152/ajpcell.00123.2019

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  117. www.nature.com www.nature.com
    Inducible mouse models of colon cancer for the analysis of sporadic and inflammation-driven tumor progression and lymph node metastasis
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  118. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Touchscreen-based location discrimination and paired associate learning tasks detect cognitive impairment at an early stage in an App knock-in mouse model of Alzheimer’s disease
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      DOI: 10.1186/s13041-020-00690-6

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  119. www.nature.com www.nature.com
    Single-cell imaging of human cancer xenografts using adult immunodeficient zebrafish
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  120. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Heme Oxygenase 1 in Schwann Cells Regulates Peripheral Nerve Degeneration Against Oxidative Stress
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      DOI: 10.1177/1759091419838949

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  121. www.cell.com www.cell.com
    Preclinical Efficacy and Safety of a Human Embryonic Stem Cell-Derived Midbrain Dopamine Progenitor Product, MSK-DA01
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    cell.com/cell-stem-cell/abstract/S1934-5909(21)00004-7
  122. academic.oup.com academic.oup.com
    Preconception alcohol exposure increases the susceptibility to diabetes in the offspring
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      DOI: 10.1210/endocr/bqaa188

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    Protocol for generating human induced neural progenitor cells from immobilized adult peripheral blood
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    TAMEP are brain tumor parenchymal cells controlling neoplastic angiogenesis and progression
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  125. Jan 2021
  126. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Reciprocal interaction between mesenchymal stem cells and transit amplifying cells regulates tissue homeostasis
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      DOI: 10.7554/eLife.59459

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    Three-dimensional interactions between enhancers and promoters during intestinal differentiation depend upon HNF4
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  128. faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com
    Monomeric/dimeric forms of Fgf15/FGF19 show differential activity in hepatocyte proliferation and metabolic function
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      DOI: 10.1096/fj.202002203R

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  129. Dec 2020
  130. www.frontiersin.org www.frontiersin.org
    Primary Extracellular Matrix Enables Long-Term Cultivation of Human Tumor Oral Mucosa Models
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      DOI: 10.3389/fbioe.2020.579896

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    Talpid3-Mediated Centrosome Integrity Restrains Neural Progenitor Delamination to Sustain Neurogenesis by Stabilizing Adherens Junctions
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    Identification of tumor‐associated macrophage subsets that are associated with breast cancer prognosis
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  133. Nov 2020
  134. www.sciencedirect.com www.sciencedirect.com
    Cathepsin S Regulates Antigen Processing and T Cell Activity in Non-Hodgkin Lymphoma
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  135. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Touchscreen-based location discrimination and paired associate learning tasks detect cognitive impairment at an early stage in an App knock-in mouse model of Alzheimer’s disease
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  136. Oct 2020
  137. www.sciencedirect.com www.sciencedirect.com
    Prdm16 Deficiency Leads to Age-Dependent Cardiac Hypertrophy, Adverse Remodeling, Mitochondrial Dysfunction, and Heart Failure
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    Unacylated-Ghrelin Impairs Hippocampal Neurogenesis and Memory in Mice and Is Altered in Parkinson’s Dementia in Humans
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  139. Sep 2020
  140. www.sciencedirect.com www.sciencedirect.com
    Bacteria Boost Mammalian Host NAD Metabolism by Engaging the Deamidated Biosynthesis Pathway
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    Homeostatic and tumourigenic activity of SOX2+ pituitary stem cells is controlled by the LATS/YAP/TAZ cascade
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    Constitutive CHK1 expression drives a pSTAT3-CIP2A circuit that promotes glioblastoma cell survival and growth
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    SFPQ Depletion Is Synthetically Lethal with BRAFV600E in Colorectal Cancer Cells
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    Hormonal Suppression of Stem Cells Inhibits Symmetric Cell Division and Gastric Tumorigenesis
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    Metformin Promotes Anti-tumor Biomarkers in Human Endometrial Cancer Cells
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    Bitter melon juice intake with gemcitabine intervention circumvents resistance to gemcitabine in pancreatic patient‐derived xenograft tumors
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    The Natural Metabolite 4-Cresol Improves Glucose Homeostasis and Enhances β-Cell Function
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    Oxygen-enhanced optoacoustic tomography reveals the effectiveness of targeting heme and oxidative phosphorylation at normalizing tumor vascular oxygenation
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    FASN-Dependent Lipid Metabolism Links Neurogenic Stem/Progenitor Cell Activity to Learning and Memory Deficits
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    The novel ciliogenesis regulator DYRK2 governs Hedgehog signaling during mouse embryogenesis
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    Mouse Ovarian Cancer Models Recapitulate the Human Tumor Microenvironment and Patient Response to Treatment
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    Chronic Hyperglycemia Impairs Hippocampal Neurogenesis and Memory in an Alzheimer’s disease mouse model
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    HIV-1 Vpr induces cell cycle arrest and enhances viral gene expression by depleting CCDC137
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    The Oncogenic Action of NRF2 Depends on De-glycation by Fructosamine-3-Kinase
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    Charge-Balanced Electrical Stimulation Can Modulate Neural Precursor Cell Migration in the Presence of Endogenous Electric Fields in Mouse Brains
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    PDGFR-β Signaling Regulates Cardiomyocyte Proliferation and Myocardial Regeneration
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    Functionally Distinct Connectivity of Developmentally Targeted Striosome Neurons
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    Antagonistic interaction between Ezh2 and Arid1a coordinates root patterning and development via Cdkn2a in mouse molars
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    Gut microbiota from colorectal cancer patients enhances the progression of intestinal adenoma in Apcmin/+ mice
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    PRDM16 Maintains Homeostasis of the Intestinal Epithelium by Controlling Region-Specific Metabolism
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    Humanized Stem Cell Models of Pediatric Medulloblastoma Reveal an Oct4/mTOR Axis that Promotes Malignancy
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    Use of a Mouse Model of Experimentally Induced Endometriosis to Evaluate and Compare the Effects of Bisphenol A and Bisphenol AF Exposure
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    The COMPASS Family Protein ASH2L Mediates Corticogenesis via Transcriptional Regulation of Wnt Signaling
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    Metformin Restores CNS Remyelination Capacity by Rejuvenating Aged Stem Cells
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    The Polycomb Repressor Complex 1 Drives Double-Negative Prostate Cancer Metastasis by Coordinating Stemness and Immune Suppression
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    Neural crest-specific deletion of Rbfox2 in mice leads to craniofacial abnormalities including cleft palate
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    ETS Proteins Bind with Glucocorticoid Receptors: Relevance for Treatment of Ewing Sarcoma
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    Identification of a LIF-Responsive, Replication-Competent Subpopulation of Human β Cells
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    Decreased beta cell proliferation and vascular density in a subpopulation of low-oxygenated male rat islets
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    ROR1-CAR T-cells are effective against lung and breast cancer in advanced microphysiologic 3D tumor models
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    Chronic Inflammation Directs an Olfactory Stem Cell Functional Switch from Neuroregeneration to Immune Defense
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