While more traditional therapies such as chemotherapy and radiotherapy lack tumor specificity targeting all replicating cells, and other immunotherapies have limited scope by relying on the presence of a specific ligand/receptor, oncolytic viruses are postulated to be both specific to neoplastic cells and have an expansive immunostimulatory latitude. The
Chemo and Radiation lack specificity in targetting cancerous cells, instead targeting a large scope or rapidly dividing cells.
Immunotherapies are limited to the presence of ligand and receptors for activation.
Oncolytic viruses are specific to neoplastic (cancerous, specific) cells and have a large amount of immunostimulatory range----> can activate tumor immunity, stimulate immune system......