1 Matching Annotations
- Sep 2023
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Defections from large-scale anatomical goals, such as those that occur due to an inappropriate reduction of gap junctional connectivity [74], present as cancer, cause reversions of cell behavior to ancient unicellular concerns which lead to metastasis and over-proliferation as the cells treat the rest of the body as external environment.
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fresh perspective
- cancer can be interpreted as a breakdown in the bodies multiscale competency architecture causing cancerous cells to lose their higher level synchronizing signals and revert to their more evolutionarily primitive forms as individuals that see the body as simply an external environment
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adjacency between
- gap junction coupling
- cancer
- healthy tissue coherence
- multiscale competency architecture
- adjacency statement
- gap junction coupling appears to be an evolutionary means of cohering individuals together to form a larger group
- hence, they seem to play a critical role in the continued evolution of more complex multicellular organisms
- their pathologies within multicellular beings destroy multicellular structures and create disease, reverting the organism, or competent multicellular structures of the organism such as tissues and organs back to individualistic behavior, as in cancers
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