The hit rate was found to be much lower thanthat of the fragment screen
the author implied that fragment screening usually has higher hit rate than drug size library screening.
4 Matching Annotations
- Apr 2020
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Local file Local file
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a hit rate of about 4%
hit rate of 4% by DSF is similar to that of screening against kinase targets, interesting.
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fragment library
fragment screening for binders are really powerful. this library contains 800 fragments
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- Mar 2020
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pubs.acs.org pubs.acs.org
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covalent fragment screening
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