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- Dec 2019
Case histories are presented showing rapid recovery (less than 7 days) from major depression using 125-300 mg of magnesium (as glycinate and taurinate) with each meal and at bedtime. Magnesium was found usually effective for treatment of depression in general use.
Sounds like 500-1200 mg per day (i.e. 125-300 mg four times daily). While 500 mg daily seems fairly normal, 1200 mg is rather high. That dose may require highly bioavailable forms to avoid side effects. I think that this is the study I've been searching for ever since I lost track of it. So far, this is the highest dose of elemental magnesium that I'm aware of being studied.