Case#: female; age 65

DiseaseAssertion: chemotherapy-induced cardiomyopathy with severe left ventricular systolic dysfunction

FamilyInfo: NR

ParentalTesting: NR

CasePresentingHPOs: HP:0001644 HP:0001635 HP:0001640

CaseHPOFreeText: Dilated left ventricle; left ventricular dysfunction; cardiomegaly; bilateral pleural effusion; dyspnea

CaseNotHPOs: NR

CaseNotHPOFreeText: NR

CasePreviousTesting: Previous anthracycline-associated cardiomyopathy 7 years earlier

Genotyping Method: TruSight One Expanded 6700-gene sequencing panel on an Illumina NextSeq 550

FunctionalAnalysis: NR

Variant: c.452G>A (p.Arg151Gln; rs730881101); missense variant; heterozygous

ClinVar: 181617

CAID: NR

gnomAD: NR