78 Matching Annotations
  1. Jun 2024
  2. www.sciencedirect.com www.sciencedirect.com
    Bacterial esterases reverse lipopolysaccharide ubiquitylation to block host immunity
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    1. scibot 21 Jun 2024
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    sciencedirect.com/science/article/pii/S193131282400132X
  3. May 2024
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    Deletion of the mRNA endonuclease Regnase-1 promotes NK cell anti-tumor activity via OCT2-dependent transcription of Ifng
    2
    1. scibot 31 May 2024
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      DOI: 10.1016/j.immuni.2024.05.006

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    2. scibot 31 May 2024
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      DOI: 10.1016/j.immuni.2024.05.006

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    sciencedirect.com/science/article/pii/S1074761324002590
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    Tumor mitochondrial oxidative phosphorylation stimulated by the nuclear receptor RORγ represents an effective therapeutic opportunity in osteosarcoma
    1
    1. scibot 03 May 2024
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      DOI: 10.1016/j.xcrm.2024.101519

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    cell.com/cell-reports-medicine/abstract/S2666-3791(24)00188-5
  6. Apr 2024
  7. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Membrane-bound O-acyltransferase 7 (MBOAT7) shapes lysosomal lipid homeostasis and function to control alcohol-associated liver injury
    1
    1. scibot 24 Apr 2024
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      DOI: 10.7554/eLife.92243

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    ncbi.nlm.nih.gov/pmc/articles/PMC11034944/
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    Semaphorin3C identified as mediator of neuroinflammation and microglia polarization after spinal cord injury
    1
    1. scibot 23 Apr 2024
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      DOI: 10.1016/j.isci.2024.109649

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    ncbi.nlm.nih.gov/pmc/articles/PMC11025009/
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    Generation of human cerebral organoids with a structured outer subventricular zone
    1
    1. scibot 09 Apr 2024
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      DOI: 10.1016/j.celrep.2024.114031

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    sciencedirect.com/science/article/pii/S2211124724003590
  10. Mar 2024
  11. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Assembly of neuron- and radial glial-cell-derived extracellular matrix molecules promotes radial migration of developing cortical neurons
    1
    1. scibot 23 Mar 2024
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      DOI: 10.7554/eLife.92342

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    ncbi.nlm.nih.gov/pmc/articles/PMC10957175/
  12. Jan 2024
  13. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Tanshinone IIA reverses gefitinib resistance in EGFR-mutant lung cancer via inhibition of SREBP1-mediated lipogenesis
    1
    1. scibot 31 Jan 2024
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      DOI: 10.1002/ptr.8130

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    onlinelibrary.wiley.com/doi/10.1002/ptr.8130
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    Arachidonic acid inhibition of the NLRP3 inflammasome is a mechanism to explain the anti-inflammatory effects of fasting
    2
    1. scibot 25 Jan 2024
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      DOI: 10.1016/j.celrep.2024.113700

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    2. scibot 25 Jan 2024
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      DOI: 10.1016/j.celrep.2024.113700

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    sciencedirect.com/science/article/pii/S2211124724000287
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    Formate supplementation enhances anti-tumor CD8+ T cell fitness and efficacy of PD-1 blockade
    1
    1. scibot 11 Jan 2024
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      DOI: 10.1158/2159-8290.CD-22-1301

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    dx.doi.org/10.1158/2159-8290.CD-22-1301
  16. Dec 2023
  17. www.sciencedirect.com www.sciencedirect.com
    Pib2 is a cysteine sensor involved in TORC1 activation in Saccharomyces cerevisiae
    1
    1. scibot 22 Dec 2023
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      DOI: 10.1016/j.celrep.2023.113599

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    sciencedirect.com/science/article/pii/S221112472301611X
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    Profiling nuclear cysteine ligandability and effects on nuclear localization using proximity labeling-coupled chemoproteomics
    1
    1. scibot 17 Dec 2023
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      DOI: 10.1016/j.chembiol.2023.11.010

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    sciencedirect.com/science/article/pii/S2451945623004257
  19. 52.53.155.43 52.53.155.43
    cd-22-1301-html.html
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    1. scibot 01 Dec 2023
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    52.53.155.43/ed2c7eab61775ee4a9efbdfa91d6b4b18a13354a/cd-22-1301-html.html
  20. Sep 2023
  21. www.sciencedirect.com www.sciencedirect.com
    Essential role of the amino-terminal region of Drosha for the Microprocessor function
    1
    1. scibot 30 Sep 2023
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      DOI: 10.1016/j.isci.2023.107971

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    sciencedirect.com/science/article/pii/S2589004223020485
  22. Aug 2023
  23. 52.53.155.43 52.53.155.43
    Nuclear transport surveillance of p53 by nuclear pores in glioblastoma
    2
    1. scibot 12 Aug 2023
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      DOI: 10.1016/j.celrep.2023.112882

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      DOI: 10.1016/j.celrep.2023.112882

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    52.53.155.43/64ae675a86b73874b1bb5c50aa8d9678e93e36d6/PIIS2211124723008938-html.html
  24. Jul 2023
  25. www.sciencedirect.com www.sciencedirect.com
    Disruption of neuronal RHEB signaling impairs oligodendrocyte differentiation and myelination through mTORC1-DLK1 axis
    1
    1. scibot 21 Jul 2023
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      DOI: 10.1016/j.celrep.2023.112801

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    sciencedirect.com/science/article/pii/S2211124723008124
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    Elevated FBXW10 drives hepatocellular carcinoma tumorigenesis via AR-VRK2 phosphorylation-dependent GAPDH ubiquitination in male transgenic mice
    1
    1. scibot 15 Jul 2023
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      DOI: 10.1016/j.celrep.2023.112812

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    sciencedirect.com/science/article/pii/S2211124723008239
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    Activation of autophagy depends on Atg1/Ulk1-mediated phosphorylation and inhibition of the Hsp90 chaperone machinery
    1
    1. scibot 15 Jul 2023
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      DOI: 10.1016/j.celrep.2023.112807

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    sciencedirect.com/science/article/pii/S2211124723008185
  28. Apr 2023
  29. www.sciencedirect.com www.sciencedirect.com
    Sodium ion influx regulates liquidity of biomolecular condensates in hyperosmotic stress response
    1
    1. scibot 06 Apr 2023
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      DOI: 10.1016/j.celrep.2023.112315

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    sciencedirect.com/science/article/pii/S2211124723003261
  30. Mar 2023
  31. www.sciencedirect.com www.sciencedirect.com
    An optimized protocol to detect protein ubiquitination and activation by ubiquitination assay in vivo and CCK-8 assay
    1
    1. scibot 28 Mar 2023
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      DOI: 10.1016/j.xpro.2023.102199

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    sciencedirect.com/science/article/pii/S2666166723001570
  32. Feb 2023
  33. www.sciencedirect.com www.sciencedirect.com
    Exercise-activated hepatic autophagy via the FN1-α5β1 integrin pathway drives metabolic benefits of exercise
    1
    1. scibot 23 Feb 2023
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      DOI: 10.1016/j.cmet.2023.01.011

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    sciencedirect.com/science/article/pii/S1550413123000116
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    Targeted pseudouridylation: An approach for suppressing nonsense mutations in disease genes
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    1. scibot 10 Feb 2023
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      DOI: 10.1016/j.molcel.2023.01.009

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    sciencedirect.com/science/article/pii/S1097276523000291
  35. Jan 2023
  36. www.sciencedirect.com www.sciencedirect.com
    Prolonged hypernutrition impairs TREM2-dependent efferocytosis to license chronic liver inflammation and NASH development
    1
    1. scibot 28 Jan 2023
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      DOI: 10.1016/j.immuni.2022.11.013

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    sciencedirect.com/science/article/pii/S1074761322006033
  37. Dec 2022
  38. www.sciencedirect.com www.sciencedirect.com
    Mechanism of IFT-A polymerization into trains for ciliary transport
    1
    1. scibot 24 Dec 2022
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      DOI: 10.1016/j.cell.2022.11.033

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    sciencedirect.com/science/article/pii/S0092867422015082
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    Crosstalk between pro-survival sphingolipid metabolism and complement signaling induces inflammasome-mediated tumor metastasis
    1
    1. scibot 08 Dec 2022
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      DOI: 10.1016/j.celrep.2022.111742

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    sciencedirect.com/science/article/pii/S2211124722016205
  40. Sep 2022
  41. www.sciencedirect.com www.sciencedirect.com
    Endothelial caveolin-1 regulates cerebral thrombo-inflammation in acute ischemia/reperfusion injury
    1
    1. scibot 23 Sep 2022
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      DOI: 10.1016/j.ebiom.2022.104275

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    sciencedirect.com/science/article/pii/S2352396422004571
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    Cancer cell autophagy, reprogrammed macrophages, and remodeled vasculature in glioblastoma triggers tumor immunity
    1
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      DOI: 10.1016/j.ccell.2022.08.014

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    sciencedirect.com/science/article/pii/S1535610822003786
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    Methionine metabolism controls the B cell EBV epigenome and viral latency
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      DOI: 10.1016/j.cmet.2022.08.008

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    sciencedirect.com/science/article/pii/S1550413122003515
  44. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Loss of oligodendrocyte ErbB receptor signaling leads to hypomyelination, reduced density of parvalbumin-expressing interneurons, and inhibitory function in the auditory cortex
    1
    1. scibot 07 Sep 2022
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      DOI: 10.1002/glia.24266

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    onlinelibrary.wiley.com/doi/10.1002/glia.24266
  45. Jul 2022
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    A specialized Hsp90 co-chaperone network regulates steroid hormone receptor response to ligand
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      DOI: 10.1016/j.celrep.2022.111039

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    sciencedirect.com/science/article/pii/S2211124722008336
  47. Jun 2022
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    Neutrophil Extracellular Traps Mediate Acute Liver Failure in Regulation of miR-223/neutrophil Elastase Signaling in Mice
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      DOI: 10.1016/j.jcmgh.2022.05.012

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    sciencedirect.com/science/article/pii/S2352345X22000972
  49. Dec 2021
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    β-catenin links cell seeding density to global gene expression during mouse embryonic stem cell differentiation
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      DOI: 10.1016/j.isci.2021.103541

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    sciencedirect.com/science/article/pii/S2589004221015121
  51. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Elevated FBXO45 promotes liver tumorigenesis through enhancing IGF2BP1 ubiquitination and subsequent PLK1 upregulation
    1
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      DOI: 10.7554/eLife.70715

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    ncbi.nlm.nih.gov/pmc/articles/PMC8641947/
  52. Oct 2021
  53. www.sciencedirect.com www.sciencedirect.com
    PARP1-mediated PARylation activity is essential for oligodendroglial differentiation and CNS myelination
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      DOI: 10.1016/j.celrep.2021.109695

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    sciencedirect.com/science/article/pii/S2211124721011426
  54. Sep 2021
  55. www.sciencedirect.com www.sciencedirect.com
    Noncanonical mono(ADP-ribosyl)ation of zinc finger SZF proteins counteracts ubiquitination for protein homeostasis in plant immunity
    1
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      DOI: 10.1016/j.molcel.2021.09.006

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    sciencedirect.com/science/article/pii/S1097276521007401
  56. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Efficient Generation of Multi-gene Knockout Cell Lines and Patient-derived Xenografts Using Multi-colored Lenti-CRISPR-Cas9
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      DOI: 10.21769/BioProtoc.2222

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    ncbi.nlm.nih.gov/pmc/articles/PMC8410427/
  57. Aug 2021
  58. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Autophagy regulates inflammatory programmed cell death via turnover of RHIM-domain proteins
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      DOI: 10.7554/eLife.44452

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    TNIK is a therapeutic target in Lung Squamous Cell Carcinoma and regulates FAK activation through Merlin.
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    Obesity-Linked PPARγ S273 Phosphorylation Promotes Insulin Resistance through Growth Differentiation Factor 3
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    Coordinated Splicing of Regulatory Detained Introns within Oncogenic Transcripts Creates an Exploitable Vulnerability in Malignant Glioma
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