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  1. Last 7 days
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    The activity of early-life gene regulatory elements is hijacked in aging through pervasive AP-1-linked chromatin opening
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    1. scibot 19 Jul 2024
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    sciencedirect.com/science/article/pii/S1550413124002316
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    Preclinical study and phase II trial of adapting low-dose radiotherapy to immunotherapy in small cell lung cancer
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    sciencedirect.com/science/article/pii/S2666634024002484
  4. Jul 2024
  5. www.cell.com www.cell.com
    Pan-cancer mapping of single CD8+ T cell profiles reveals a TCF1:CXCR6 axis regulating CD28 co-stimulation and anti-tumor immunity
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    cell.com/cell-reports-medicine/abstract/S2666-3791(24)00353-7
  6. May 2024
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    The CD8+ T cell tolerance checkpoint triggers a distinct differentiation state defined by protein translation defects
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    Platinum-Based Chemotherapy Attenuates the Effector Response of CD8 T Cells to Concomitant PD-1 Blockade
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    ncbi.nlm.nih.gov/pmc/articles/PMC11061601/
  9. 52.53.155.43 52.53.155.43
    Hypomethylation-enhanced CRTC2 expression drives malignant phenotypes and primary resistance to immunotherapy in hepatocellular carcinoma
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  10. Apr 2024
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    IFNα-induced BST2+ tumor-associated macrophages facilitate immunosuppression and tumor growth in pancreatic cancer by ERK-CXCL7 signaling
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    sciencedirect.com/science/article/pii/S2211124724004169
  12. Mar 2024
  13. www-cell-com.proxy.uchicago.edu www-cell-com.proxy.uchicago.edu
    Microbial metabolite enhances immunotherapy efficacy by modulating T cell stemness in pan-cancer
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    1. scibot 15 Mar 2024
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    www-cell-com.proxy.uchicago.edu/cell/fulltext/S0092-8674(24)00224-1
  14. Feb 2024
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    RORα is required for expansion and memory maintenance of ILC1s via a lymph node-liver axis
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    sciencedirect.com/science/article/pii/S2211124724001141
  16. Jan 2024
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    Inosine induces stemness features in CAR-T cells and enhances potency
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    miRNA-194-3p represses NF-κB in gliomas to attenuate iPSC genes and proneural to mesenchymal transition.
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    ncbi.nlm.nih.gov/pmc/articles/PMC10788216/
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    Mitochondrial isocitrate dehydrogenase impedes CAR T cell function by restraining antioxidant metabolism and histone acetylation
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    sciencedirect.com/science/article/pii/S1550413123004618
  20. Dec 2023
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    Dihydroartemisinin inhibits the development of colorectal cancer by GSK-3β/TCF7/MMP9 pathway and synergies with capecitabine
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    sciencedirect.com/science/article/pii/S0304383523005475
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    Heterogeneity and transcriptional drivers of triple-negative breast cancer
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    sciencedirect.com/science/article/pii/S2211124723015760
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    Integrated multi-omics profiling to dissect the spatiotemporal evolution of metastatic hepatocellular carcinoma
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    sciencedirect.com/science/article/pii/S1535610823004014
  24. Nov 2023
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    Targeted perturbation of signaling-driven condensates
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    sciencedirect.com/science/article/pii/S1097276523008602
  26. Oct 2023
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    Reciprocal transmission of activating and inhibitory signals and cell fate in regenerating T cells
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    sciencedirect.com/science/article/pii/S2211124723011671
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    Peritumoral Immune-suppressive Mechanisms Impede Intratumoral Lymphocyte Infiltration into Colorectal Cancer Liver versus Lung Metastases
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      DOI: 10.1158/2767-9764.CRC-23-0212

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    dx.doi.org/10.1158/2767-9764.CRC-23-0212
  29. Sep 2023
  30. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Activation of AKT induces EZH2-mediated β-catenin trimethylation in colorectal cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC10475482/
  31. May 2023
  32. 52.53.155.43 52.53.155.43
    Memory profiles distinguish cross-reactive and virus-specific T cell immunity to mpox
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    52.53.155.43/aae233627c38e3a0d2b4954ede67725a876f2844/1-s2.0-S193131282300166X-main-html.html
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    CCL19+ dendritic cells potentiate clinical benefit of anti-PD-(L)1 immunotherapy in triple-negative breast cancer
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    Tailoring vascular phenotype through AAV therapy promotes anti-tumor immunity in glioma
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    sciencedirect.com/science/article/pii/S1535610823001368
  35. Jan 2023
  36. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    P2RX7 enhances tumor control by CD8+ T cells in adoptive cell therapy
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    ncbi.nlm.nih.gov/pmc/articles/PMC9250641/
  37. Nov 2022
  38. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    R-spondin 3 deletion induces Erk phosphorylation to enhance Wnt signaling and promote bone formation in the appendicular skeleton
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      DOI: 10.7554/eLife.84171

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    ncbi.nlm.nih.gov/pmc/articles/PMC9681208/
  39. www.cell.com www.cell.com
    Cancer immunotherapies transition endothelial cells into HEVs that generate TCF1+ T lymphocyte niches through a feed-forward loop
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    cell.com/cancer-cell/fulltext/S1535-6108(22)00549-9
  40. Aug 2022
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    SOX transcription factors direct TCF-independent WNT/β-catenin responsive transcription to govern cell fate in human pluripotent stem cells
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    sciencedirect.com/science/article/pii/S2211124722010658
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    Internal checkpoint regulates T cell neoantigen reactivity and susceptibility to PD1 blockade
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  43. Jul 2022
  44. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Efficacy of Combined Use of Everolimus and Second-Generation Pan-EGRF Inhibitors in KRAS Mutant Non-Small Cell Lung Cancer Cell Lines
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      DOI: 10.3390/ijms23147774

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    ncbi.nlm.nih.gov/pmc/articles/PMC9317664/
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    Mapping hormone-regulated cell-cell interaction networks in the human breast at single-cell resolution
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    sciencedirect.com/science/article/pii/S2405471222002757
  46. Jun 2022
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    BCL6-dependent TCF-1+ progenitor cells maintain effector and helper CD4+ T cell responses to persistent antigen
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    sciencedirect.com/science/article/pii/S1074761322002230
  48. May 2022
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    Twist2-driven chromatin remodeling governs the postnatal maturation of dermal fibroblasts
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    sciencedirect.com/science/article/pii/S2211124722005927
  50. Apr 2022
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    Distinct phenotypic states and spatial distribution of CD8+ T cell clonotypes in human brain metastases
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    sciencedirect.com/science/article/pii/S2666379122001379
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    The mitochondrial pyruvate carrier regulates memory T cell differentiation and antitumor function
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    sciencedirect.com/science/article/pii/S1550413122001279
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    Ovarian cancer immunogenicity is governed by a narrow subset of progenitor tissue-resident memory T cells
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    sciencedirect.com/science/article/pii/S1535610822001234
  54. Mar 2022
  55. www.sciencedirect.com www.sciencedirect.com
    AXL targeting restores PD-1 blockade sensitivity of STK11/LKB1 mutant NSCLC through expansion of TCF1+ CD8 T cells
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      DOI: 10.1016/j.xcrm.2022.100554

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    Tfh-cell-derived interleukin 21 sustains effector CD8+ T cell responses during chronic viral infection
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      DOI: 10.1016/j.immuni.2022.01.018

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  57. Jan 2022
  58. www.sciencedirect.com www.sciencedirect.com
    CXCR3 regulates stem and proliferative CD8+ T cells during chronic infection by promoting interactions with DCs in splenic bridging channels
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      DOI: 10.1016/j.celrep.2021.110266

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    sciencedirect.com/science/article/pii/S2211124721017782
  59. Dec 2021
  60. www.sciencedirect.com www.sciencedirect.com
    Vectored antibody gene delivery restores host B and T cell control of persistent viral infection
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      DOI: 10.1016/j.celrep.2021.110061

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    sciencedirect.com/science/article/pii/S2211124721015473
  61. Nov 2021
  62. www.sciencedirect.com www.sciencedirect.com
    CXCL10 chemokine regulates heterogeneity of the CD8+ T cell response and viral set point during chronic infection
    1
    1. scibot 30 Nov 2021
      RRID:AB_2199302

      DOI: 10.1016/j.immuni.2021.11.002

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    sciencedirect.com/science/article/pii/S1074761321004933
  63. Sep 2021
  64. www.sciencedirect.com www.sciencedirect.com
    TCF/LEF regulation of the topologically associated domain ADI promotes mESCs to exit the pluripotent ground state
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    1. scibot 16 Sep 2021
      RRID:AB_2199302

      DOI: 10.1016/j.celrep.2021.109705

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    sciencedirect.com/science/article/pii/S2211124721011529
  65. www.sciencedirect.com www.sciencedirect.com
    PD-1+ Tcf1+ CD8+ T cells from established chronic infection can form memory while retaining a stableimprint of persistent antigen exposure
    1
    1. scibot 08 Sep 2021
      RRID:AB_2199302

      DOI: 10.1016/j.celrep.2021.109672

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    sciencedirect.com/science/article/pii/S2211124721011165
  66. Aug 2021
  67. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    LMO2 is essential to maintain the ability of progenitors to differentiate into T-cell lineage in mice
    1
    1. scibot 17 Aug 2021
      RRID:AB_2199302

      DOI: 10.7554/eLife.68227

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    ncbi.nlm.nih.gov/pmc/articles/PMC8360648/
  68. www.sciencedirect.com www.sciencedirect.com
    KDM5 Histone Demethylase Activity Links Cellular Transcriptomic Heterogeneity to Therapeutic Resistance
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    1. scibot 07 Aug 2021
      RRID:AB_2199302

      DOI: 10.1016/j.ccell.2018.10.014

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    sciencedirect.com/science/article/pii/S153561081830480X
  69. Jul 2021
  70. www.sciencedirect.com www.sciencedirect.com
    Defining T Cell States Associated with Response to Checkpoint Immunotherapy in Melanoma
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    1. scibot 30 Jul 2021
      RRID:AB_2199302

      DOI: 10.1016/j.cell.2018.10.038

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    sciencedirect.com/science/article/pii/S0092867418313941
  71. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Deep spatial profiling of human COVID-19 brains reveals neuroinflammation with distinct microanatomical microglia-T-cell interactions
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      RRID:AB_2199302

      DOI: 10.1016/j.immuni.2021.06.002

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    ncbi.nlm.nih.gov/pmc/articles/PMC8188302/
  72. Jun 2021
  73. www.sciencedirect.com www.sciencedirect.com
    Dermal EZH2 orchestrates dermal differentiation and epidermal proliferation during murine skin development
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      RRID:AB_2199302

      DOI: 10.1016/j.ydbio.2021.06.008

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    sciencedirect.com/science/article/pii/S0012160621001500
  74. May 2021
  75. www.sciencedirect.com www.sciencedirect.com
    Central memory CD8+ T cells derive from stem-like Tcf7hi effector cells in the absence of cytotoxic differentiation
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    1. scibot 07 May 2021
      RRID:AB_2199302

      DOI: 10.1016/j.immuni.2020.09.005

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    sciencedirect.com/science/article/pii/S107476132030399X
  76. www.sciencedirect.com www.sciencedirect.com
    Multi-tissue single-cell analysis deconstructs the complex programs of mouse natural killer and type 1 innate lymphoid cells in tissues and circulation
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    1. scibot 04 May 2021
      RRID:AB_2199302

      DOI: 10.1016/j.immuni.2021.03.024

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    sciencedirect.com/science/article/pii/S1074761321001369
  77. Apr 2021
  78. www.sciencedirect.com www.sciencedirect.com
    A unified atlas of CD8 T cell dysfunctional states in cancer and infection
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    1. scibot 23 Apr 2021
      RRID:AB_2199302

      DOI: 10.1016/j.molcel.2021.03.045

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    sciencedirect.com/science/article/pii/S1097276521002665
  79. Mar 2021
  80. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A β-catenin-driven switch in TCF/LEF transcription factor binding to DNA target sites promotes commitment of mammalian nephron progenitor cells
    1
    1. scibot 09 Mar 2021
      RRID:AB_2199302

      DOI: 10.7554/eLife.64444

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    ncbi.nlm.nih.gov/pmc/articles/PMC7924951/
  81. Feb 2021
  82. elifesciences.org elifesciences.org
    The kinase PDK1 is critical for promoting T follicular helper cell differentiation
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    1. scibot 25 Feb 2021
      RRID:AB_2199302

      DOI: 10.7554/eLife.61406

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  83. Sep 2020
  84. www.sciencedirect.com www.sciencedirect.com
    T Cell Factor 1 Suppresses CD103+ Lung Tissue-Resident Memory T Cell Development
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    1. scibot 04 Sep 2020
      Tcf1 (C63D9) rabbit mAb

      DOI: 10.1016/j.celrep.2020.03.048

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    sciencedirect.com/science/article/pii/S2211124720303624
  85. Jan 2020
  86. www.sciencedirect.com www.sciencedirect.com
    A Thpok-Directed Transcriptional Circuitry Promotes Bcl6 and Maf Expression to Orchestrate T Follicular Helper Differentiation
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    1. scibot 13 Jan 2020
      RRID:AB_2199302

      DOI: 10.1016/j.immuni.2019.06.023

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    sciencedirect.com/science/article/pii/S1074761319302936
  87. www.sciencedirect.com www.sciencedirect.com
    Mediator Condensates Localize Signaling Factors to Key Cell Identity Genes
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    1. scibot 13 Jan 2020
      RRID:AB_2199302

      DOI: 10.1016/j.molcel.2019.08.016

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    sciencedirect.com/science/article/pii/S1097276519306550
  88. www.sciencedirect.com www.sciencedirect.com
    CD4+ T Cell Help Is Required for the Formation of a Cytolytic CD8+ T Cell Subset that Protects against Chronic Infection and Cancer
    1
    1. scibot 13 Jan 2020
      RRID:AB_2199302

      DOI: 10.1016/j.immuni.2019.10.009

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    sciencedirect.com/science/article/pii/S1074761319304534
  89. www.sciencedirect.com www.sciencedirect.com
    Untitled document
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    1. scibot 13 Jan 2020
      RRID:AB_2199302

      DOI: 10.1016/j.immuni.2018.12.021

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    sciencedirect.com/science/article/pii/S1074761318305697
  90. Nov 2018
  91. www.sciencedirect.com www.sciencedirect.com
    Submucosal Gland Myoepithelial Cells Are Reserve Stem Cells That Can Regenerate Mouse Tracheal Epithelium
    1
    1. scibot 05 Nov 2018
      RRID:AB_2199302

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    sciencedirect.com/science/article/pii/S1934590918301231
  92. www.sciencedirect.com www.sciencedirect.com
    Temporal Layering of Signaling Effectors Drives Chromatin Remodeling during Hair Follicle Stem Cell Lineage Progression
    1
    1. scibot 05 Nov 2018
      RRID:AB_2199302

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    sciencedirect.com/science/article/pii/S1934590917305040