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Krüppel-like factors 2 and 3 regulate T cell exhaustion by directing T cell residency and migration

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1. scibot 31 Mar 2026
  
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  DOI: 10.1016/j.immuni.2026.02.021
  
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sciencedirect.com/science/article/pii/S1074761326000919
Mar 2026
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Unleashing T cell surveillance for the eradication of quiescent persister tumor cells resistant to neoadjuvant chemotherapy

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1. scibot 27 Mar 2026
  
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  DOI: 10.1016/j.devcel.2026.02.020
  
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sciencedirect.com/science/article/pii/S1534580726000857
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A hierarchical Rorc(γt) cis-regulatory cascade orchestrates differentiation of RORγt⁺ innate immune cells

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1. scibot 26 Mar 2026
  
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  DOI: 10.1016/j.immuni.2026.02.002
  
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sciencedirect.com/science/article/pii/S1074761326000543
Aug 2025
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Engineered T cells stimulate dendritic cell recruitment and antigen spreading for potent anti-tumor immunity

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1. scibot 26 Aug 2025
  
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  DOI: 10.1016/j.xcrm.2025.102307
  
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sciencedirect.com/science/article/pii/S2666379125003805
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Succinate preserves CD8+ T cell fitness to augment antitumor immunity

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1. scibot 15 Aug 2025
  
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  DOI: 10.1016/j.immuni.2025.07.017
  
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sciencedirect.com/science/article/pii/S1074761325003267
Jun 2025
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Prolonged but finite antigen presentation promotes reversible defects of “helpless” memory CD8+ T cells

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1. scibot 26 Jun 2025
  
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  DOI: 10.1016/j.immuni.2025.05.025
  
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sciencedirect.com/science/article/pii/S1074761325002468
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Membrane-bound IL-15 co-expression powers a potent and persistent CD70-targeted TRuC T-cell therapy

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1. scibot 18 Jun 2025
  
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  DOI: 10.3389/fimmu.2025.1609658
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12162932/
Apr 2025
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Pre-existing intratumoral stem-like CD8+ T cells drive radiotherapy-induced tumor immunity

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1. scibot 15 Apr 2025
  
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  DOI: 10.1016/j.celrep.2025.115566
  
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sciencedirect.com/science/article/pii/S2211124725003377
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Pre-existing intratumoral stem-like CD8+ T-cells drive radiotherapy-induced tumor control

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1. scibot 11 Apr 2025
  
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  DOI: 10.1101/2024.10.16.618635
  
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52.53.155.43/ecad09cc9eabd42f0fef0391e2d71b5d66664c67/2024.10.16.618635.full-html.html
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Cancer-cell-derived cGAMP limits the activity of tumor-associated CD8+ T cells

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1. scibot 03 Apr 2025
  
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  DOI: 10.1016/j.celrep.2025.115510
  
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sciencedirect.com/science/article/pii/S2211124725002815
Feb 2025
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AKR1D1 suppresses liver cancer progression by promoting bile acid metabolism-mediated NK cell cytotoxicity

1
1. scibot 27 Feb 2025
  
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  DOI: 10.1016/j.cmet.2025.01.011
  
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sciencedirect.com/science/article/pii/S1550413125000117
Dec 2024
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Mannose metabolism reshapes T cell differentiation to enhance anti-tumor immunity

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1. scibot 06 Dec 2024
  
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  DOI: 10.1016/j.ccell.2024.11.003
  
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sciencedirect.com/science/article/pii/S1535610824004380
Sep 2024
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A PD-1-targeted, receptor-masked IL-2 immunocytokine that engages IL-2Rα strengthens T cell-mediated anti-tumor therapies

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1. scibot 27 Sep 2024
  
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  DOI: 10.1016/j.xcrm.2024.101747
  
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sciencedirect.com/science/article/pii/S2666379124004774
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Endometrial Axin2+ Cells Drive Epithelial Homeostasis, Regeneration, and Cancer following Oncogenic Transformation

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1. scibot 25 Sep 2024
  
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  DOI: 10.1016/j.stem.2019.11.012
  
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sciencedirect.com/science/article/pii/S1934590919304679
Aug 2024
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Combination anti-PD-1 and anti-CTLA-4 therapy generates waves of clonal responses that include progenitor-exhausted CD8+ T cells

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1. scibot 30 Aug 2024
  
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  AB_2797631
  
  DOI: 10.1016/j.ccell.2024.08.007
  
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sciencedirect.com/science/article/pii/S1535610824003064
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Uncovering therapeutic targets for macrophage-mediated T cell suppression and PD-L1 therapy sensitization

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1. scibot 27 Aug 2024
  
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  DOI: 10.1016/j.xcrm.2024.101698
  
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sciencedirect.com/science/article/pii/S2666379124004191
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Aerobic glycolysis but not GLS1-dependent glutamine metabolism is critical for anti-tumor immunity and response to checkpoint inhibition

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1. scibot 22 Aug 2024
  
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  DOI: 10.1016/j.celrep.2024.114632
  
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sciencedirect.com/science/article/pii/S2211124724009823
Jul 2024
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Transcriptional programming mediated by the histone demethylase KDM5C regulates dendritic cell population heterogeneity and function

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1. scibot 25 Jul 2024
  
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  DOI: 10.1016/j.celrep.2024.114506
  
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sciencedirect.com/science/article/pii/S2211124724008350
May 2024
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T-bet deficiency and Hic1 induction override TGF-β-dependency in the formation of CD103+ intestine-resident memory CD8+ T cells

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1. scibot 23 May 2024
  
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  DOI: 10.1016/j.celrep.2024.114258
  
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sciencedirect.com/science/article/pii/S2211124724005862
Feb 2024
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RORα is required for expansion and memory maintenance of ILC1s via a lymph node-liver axis

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1. scibot 16 Feb 2024
  
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  DOI: 10.1016/j.celrep.2024.113786
  
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2. scibot 16 Feb 2024
  
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  DOI: 10.1016/j.celrep.2024.113786
  
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sciencedirect.com/science/article/pii/S2211124724001141
Jan 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

IL-15 boosts activated HBVcore-specific CD8+ progenitor cells via metabolic rebalancing in persistent HBV infection

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1. scibot 05 Jan 2024
  
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  DOI: 10.1016/j.isci.2023.108666
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10753074/
Nov 2023
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Bcl6 is a subset-defining transcription factor of lymphoid tissue inducer-like ILC3

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1. scibot 28 Nov 2023
  
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  DOI: 10.1016/j.celrep.2023.113425
  
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sciencedirect.com/science/article/pii/S2211124723014377
Oct 2023
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Reciprocal transmission of activating and inhibitory signals and cell fate in regenerating T cells

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1. scibot 14 Oct 2023
  
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  DOI: 10.1016/j.celrep.2023.113155
  
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sciencedirect.com/science/article/pii/S2211124723011671
Jul 2023
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The splicing isoform Foxp3Δ2 differentially regulates tTreg and pTreg homeostasis

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1. scibot 27 Jul 2023
  
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  DOI: 10.1016/j.celrep.2023.112877
  
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sciencedirect.com/science/article/pii/S2211124723008884
Jun 2023
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Canonical BAF complex activity shapes the enhancer landscape that licenses CD8+ T cell effector and memory fates

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1. scibot 23 Jun 2023
  
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  DOI: 10.1016/j.immuni.2023.05.005
  
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Intravenous heterologous prime-boost vaccination activates innate and adaptive immunity to promote tumor regression

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1. scibot 08 Jun 2023
  
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  DOI: 10.1016/j.celrep.2023.112599
  
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sciencedirect.com/science/article/pii/S2211124723006101
Apr 2023
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Lymphocyte networks are dynamic cellular communities in the immunoregulatory landscape of lung adenocarcinoma

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1. scibot 14 Apr 2023
  
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  DOI: 10.1016/j.ccell.2023.03.015
  
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sciencedirect.com/science/article/pii/S1535610823000880
Feb 2023
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Graft-versus-host disease is locally maintained in target tissues by resident progenitor-like T cells

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1. scibot 02 Feb 2023
  
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  DOI: 10.1016/j.immuni.2023.01.003
  
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sciencedirect.com/science/article/pii/S1074761323000134
May 2022
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Functional assessment of the cell-autonomous role of NADase CD38 in regulating CD8+ T cell exhaustion

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1. scibot 21 May 2022
  
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  DOI: 10.1016/j.isci.2022.104347
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9117873/
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Glutaminase inhibition impairs CD8 T cell activation in STK11-/Lkb1-deficient lung cancer

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1. scibot 05 May 2022
  
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  DOI: 10.1016/j.cmet.2022.04.003
  
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cell.com/cell-metabolism/fulltext/S1550-4131(22)00130-9
Apr 2022
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Ovarian cancer immunogenicity is governed by a narrow subset of progenitor tissue-resident memory T cells

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1. scibot 15 Apr 2022
  
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  DOI: 10.1016/j.ccell.2022.03.008
  
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2. scibot 15 Apr 2022
  
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  DOI: 10.1016/j.ccell.2022.03.008
  
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sciencedirect.com/science/article/pii/S1535610822001234
Mar 2022
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Human epigenetic and transcriptional T cell differentiation atlas for identifying functional T cell-specific enhancers

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1. scibot 09 Mar 2022
  
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  DOI: 10.1016/j.immuni.2022.02.004
  
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sciencedirect.com/science/article/pii/S107476132200084X
Nov 2021
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CXCL10 chemokine regulates heterogeneity of the CD8+ T cell response and viral set point during chronic infection

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1. scibot 30 Nov 2021
  
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  DOI: 10.1016/j.immuni.2021.11.002
  
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sciencedirect.com/science/article/pii/S1074761321004933
Sep 2021
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Antigen dominance hierarchies shape TCF1+ progenitor CD8 T cell phenotypes in tumors

1
1. scibot 24 Sep 2021
  
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  DOI: 10.1016/j.cell.2021.08.020
  
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sciencedirect.com/science/article/pii/S0092867421009946
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Conventional type I dendric cells maintain a reservoir of proliferative tumor-antigen specific TCF-1+ CD8+ T cells in tumor-draining lymph nodes

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1. scibot 17 Sep 2021
  
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  RRID:AB_2797631
  
  DOI: 10.1016/j.immuni.2021.08.026
  
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sciencedirect.com/science/article/pii/S1074761321003605
Aug 2021
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The CD155/TIGIT axis promotes and maintains immune evasion in neoantigen-expressing pancreatic cancer

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1. scibot 15 Aug 2021
  
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  RRID:AB_2797631
  
  DOI: 10.1016/j.ccell.2021.07.007
  
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sciencedirect.com/science/article/pii/S1535610821003846
Jul 2021
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Transforming growth factor-β-regulated mTOR activity preserves cellular metabolism to maintain long-term T cell responses in chronic infection

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1. scibot 07 Jul 2021
  
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  RRID:AB_2797631
  
  DOI: 10.1016/j.immuni.2021.06.007
  
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sciencedirect.com/science/article/pii/S107476132100251X
Apr 2021
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UTX promotes CD8+ T cell-mediated antiviral defenses but reduces T cell durability

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1. scibot 15 Apr 2021
  
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  RRID:AB_2797631
  
  DOI: 10.1016/j.celrep.2021.108966
  
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sciencedirect.com/science/article/pii/S2211124721002801
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In vivo CRISPR screening reveals nutrient signaling processes underpinning CD8+ T cell fate decisions

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1. scibot 11 Apr 2021
  
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  RRID:AB_2797631
  
  DOI: 10.1016/j.cell.2021.02.021
  
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sciencedirect.com/science/article/pii/S0092867421001719
Sep 2020
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Developmental Relationships of Four Exhausted CD8+ T Cell Subsets Reveals Underlying Transcriptional and Epigenetic Landscape Control Mechanisms

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1. scibot 26 Sep 2020
  
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  RRID:AB_2797631
  
  DOI: 10.1016/j.immuni.2020.04.014
  
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pmc.ncbi.nlm.nih.gov/articles/PMC8360766/