104 Matching Annotations
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    CD5L promotes phagocytic removal of amyloid β oligomers and improves cognitive function in a mouse model of Alzheimer’s disease
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    High intensity 40 Hz flicker improves amyloid pathology and cognition with autophagy in 3xTg mice
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  4. May 2026
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    Escherichia coli Nissle 1917 alleviates Alzheimer’s disease in mice through OmpA-containing outer membrane vesicles
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    Design, synthesis, and biological evaluation of pyranone–carbamate hybrids as selective butyrylcholinesterase inhibitors with anti-neuroinflammatory activity for Alzheimer's disease
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    Electromagnetic field-inducible in vivo gene switch for remote spatiotemporal control of gene expression
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    Astrocytic calcium-dependent enzyme PAD2 governs microglia activity to exacerbate amyloid pathology via citrullinated vimentin
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  10. Mar 2026
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    Alzheimer’s disease pathology degrades an NMDA receptor-dependent spontaneous activity pattern in cortico-hippocampal circuits
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    Microglia-mediated protection against Alzheimer’s disease pathology and detrimental effects in white matter revealed by Ptpn6 deletion
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    MiR-34a deficiency enhances nucleic acid sensing and type I IFN signaling in a mouse model of Alzheimer’s disease
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    MerTK-triggered TGFβ1 autocrine signal regulates microglial response to neurodegeneration
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    Active immunization with bacteriophage AP205 VLPs results in reduced amyloid load and microgliosis in 5xFAD female mice
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  16. Feb 2026
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    Liver exerkine reverses aging- and Alzheimer’s-related memory loss via vasculature
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    Peripheral cancer attenuates amyloid pathology in Alzheimer’s disease via cystatin-c activation of TREM2
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  20. Dec 2025
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    Pharmacologic reversal of advanced Alzheimer’s disease in mice and identification of potential therapeutic nodes in human brain
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  22. Nov 2025
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    Spatial and single-cell transcriptomics reveal the reorganization of cerebellar microglia with aging
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  25. Oct 2025
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    Parental origin of transgene modulates amyloid-β plaque burden in the 5xFAD mouse model of Alzheimer’s disease
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    Optogenetic stimulation of midbrain dopaminergic neurons rescues hippocampal synaptic plasticity deficits in a mouse model of Alzheimer’s disease
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    Midbrain degeneration triggers astrocyte reactivity and tau pathology in experimental Alzheimer’s Disease
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    The p75 neurotrophin receptor controls the skeletal stem cell niche through sensory innervation
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    MiR-34a deficiency enhances nucleic acid sensing and type I IFN signaling in a mouse model of Alzheimer’s disease
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    Bazi Bushen improves cognitive dysfunction in 5×FAD mice by targeting amyloid pathology, neuroinflammation and cellular senescence
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    Amyloid-β-driven Alzheimer’s disease reshapes the colonic immune system in mice
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  34. Jul 2025
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    A lysosomal surveillance response to stress extends healthspan
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  36. Jun 2025
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    Myelin–axon interface vulnerability in Alzheimer’s disease revealed by subcellular proteomics and imaging of human and mouse brain
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    TNFR2 contributes to synaptic potentiation failure in hippocampal synapses and memory loss in a familial Alzheimer’s disease mouse model
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  39. May 2025
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    Selective removal of astrocytic PERK protects against glymphatic impairment and decreases toxic aggregation of β-amyloid and tau
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    Repetitive prefrontal tDCS activates VTA dopaminergic neurons, resulting in attenuation of Alzheimer’s Disease-like deficits in Tg2576 mice
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    A novel carbamate-based hybrid derivative with anti-neuroinflammatory properties as a selective butyrylcholinesterase inhibitor for Alzheimer's disease therapy
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    Misclassification in memory modification in AppNL-G-F knock-in mouse model of Alzheimer’s disease
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  45. Mar 2025
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    Systems-Level Interactome Mapping Reveals Actionable Protein Network Dysregulation Across the Alzheimer’s Disease Spectrum
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    The compound... : Neural Regeneration Research
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    GPNMB and ATP6V1A interact to mediate microglia phagocytosis of multiple types of pathological particles
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  50. Oct 2024
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    Compound (E)-2-(3,4-dihydroxystyryl)-3-hydroxy-4H-pyran-4-one downregulation of Galectin-3 ameliorates Aβ pathogenesis-induced neuroinflammation in 5 × FAD mice
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  52. Sep 2024
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    Histone Deacetylases 1 and 2 Regulate Microglia Function during Development, Homeostasis, and Neurodegeneration in a Context-Dependent Manner
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    Early-Stage Moderate Alcohol Feeding Dysregulates Insulin-Related Metabolic Hormone Expression in the Brain: Potential Links to Neurodegeneration Including Alzheimer’s Disease
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  55. Aug 2024
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    Early loss of cerebellar Purkinje cells in human and a transgenic mouse model of Alzheimer’s disease
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    Infiltrating Hematogenous Macrophages Aggregate Around β-Amyloid Plaques in an Age- and Sex-Dependent Manner in a Mouse Model of Alzheimer Disease
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  58. Jul 2024
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    Cell-specific Nav1.6 knockdown reduced astrocyte-derived Aβ by reverse Na+-Ca2+ transporter-mediated autophagy in alzheimer-like mice
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    Lack of inflammation or immune response in cyst tissue of patients with symptomatic non-hydrocephalic pineal cysts
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    Peripheral amyloid-β clearance mediates cognitive impairment in non-alcoholic fatty liver disease
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    Downregulation of Dickkopf-3, a Wnt antagonist elevated in Alzheimer's disease, restores synapse integrity and memory in a disease mouse model
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  64. Feb 2024
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    Familial Alzheimer mutations stabilize synaptotoxic γ-secretase-substrate complexes
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  66. Nov 2023
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    A genetic variant of the Wnt receptor LRP6 accelerates synapse degeneration during aging and in Alzheimer’s disease
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  68. Sep 2023
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    Endothelial senescence alleviates cognitive impairment in a mouse model of Alzheimer's disease
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    Genetic variants of phospholipase C-γ2 alter the phenotype and function of microglia and confer differential risk for Alzheimer’s disease
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  71. Aug 2023
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  73. Jul 2023
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    Evidence for a clathrin-independent endocytic pathway for APP internalization in the neuronal somatodendritic compartment
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    Hepatic soluble epoxide hydrolase activity regulates cerebral Aβ metabolism and the pathogenesis of Alzheimer’s disease in mice
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  76. May 2023
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    Emx1-Cre-mediated inactivation of PDK1 prevents plaque deposition in an Alzheimer’s disease-like mouse model
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    Oxytocin attenuates microglial activation and restores social and non-social memory in APP/PS1 Alzheimer model mice
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  80. Mar 2023
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    Genetic Variants of Phospholipase C-γ2 Confer Altered Microglial Phenotypes and Differential Risk for Alzheimer’s Disease
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    INPP5D expression is associated with risk for Alzheimer's disease and induced by plaque-associated microglia
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  83. Jan 2023
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    Microglial Expression of the Wnt Signaling Modulator DKK2 Differs between Human Alzheimer’s Disease Brains and Mouse Neurodegeneration Models
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  85. Dec 2022
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    Cognitively impaired aged Octodon degus recapitulate major neuropathological features of sporadic Alzheimer’s disease
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  87. Sep 2022
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    Association of B cell profile and receptor repertoire with the progression of Alzheimer’s disease
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    A next-generation iPSC-derived forebrain organoid model of tauopathy with tau fibrils by AAV-mediated gene transfer
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  90. Aug 2022
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    Genetic Inhibition of PDK1 Robustly Reduces Plaque Deposition and Ameliorates Gliosis in the 5×FAD Mouse Model of Alzheimer’s Disease
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  92. Jun 2022
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    The bidirectional lung brain-axis of amyloid-β pathology: ozone dysregulates the peri-plaque microenvironment
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  95. May 2022
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    Melanoma-secreted Amyloid Beta Suppresses Neuroinflammation and Promotes Brain Metastasis
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  97. Mar 2022
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    Aquaporin 4 deficiency eliminates the beneficial effects of voluntary exercise in a mouse model of Alzheimer's disease
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    Lipid flippase dysfunction as a therapeutic target for endosomal anomalies in Alzheimer’s disease
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  101. Feb 2022
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    Neuropeptide signaling and SKN-1 orchestrate differential responses of the proteostasis network to dissimilar proteotoxic insults
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  103. Jan 2022
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    Early derailment of firing properties in CA1 pyramidal cells of the ventral hippocampus in an Alzheimer's disease mouse model
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  105. Nov 2021
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  107. Oct 2021
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    Vitamin B12 impacts amyloid beta-induced proteotoxicity by regulating the methionine/S-adenosylmethionine cycle
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  109. Sep 2021
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    Cytosolic aggregation of mitochondrial proteins disrupts cellular homeostasis by stimulating the aggregation of other proteins
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  111. Aug 2021
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    iPSC-derived human microglia-like cells to study neurological diseases
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  115. Jul 2021
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    Dopamine neuronal loss contributes to memory and reward dysfunction in a model of Alzheimer’s disease
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  118. Jun 2021
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    SORL1 deficiency in human excitatory neurons causes APP-dependent defects in the endolysosome-autophagy network
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    PSD-95 protects synapses from β-amyloid
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  121. Mar 2021
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    Nilotinib restores memory function by preventing dopaminergic neuron degeneration in a mouse model of Alzheimer’s Disease
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    sciencedirect.com/science/article/pii/S0301008221000459
  123. Feb 2021
  124. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Limiting RyR2 Open Time Prevents Alzheimer’s Disease-Related Neuronal Hyperactivity and Memory Loss but Not β-Amyloid Accumulation
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    ncbi.nlm.nih.gov/pmc/articles/PMC7532726/
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    Peptide Interference with APP and Tau Association: Relevance to Alzheimer’s Disease Amelioration
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    mdpi.com/1422-0067/21/9/3270
  126. Oct 2020
  127. www.jneurosci.org www.jneurosci.org
    14,15-epoxyeicosatrienoic acid alleviates pathology in a mouse model of Alzheimer’s disease
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    jneurosci.org/content/40/42/8188
  128. Sep 2020
  129. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Limiting RyR2 Open Time Prevents Alzheimer’s Disease-Related Neuronal Hyperactivity and Memory Loss but Not β-Amyloid Accumulation
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    Opposite changes in APP processing and human Aβ levels in rats carrying either a protective or a pathogenic APP mutation
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