63 Matching Annotations
  1. Mar 2024
  2. www.sciencedirect.com www.sciencedirect.com
    Peripheral amyloid-β clearance mediates cognitive impairment in non-alcoholic fatty liver disease
    2
    1. scibot 21 Mar 2024
      RRID:AB_2564653

      DOI: 10.1016/j.ebiom.2024.105079

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    2. scibot 21 Mar 2024
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      DOI: 10.1016/j.ebiom.2024.105079

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    sciencedirect.com/science/article/pii/S2352396424001142
  3. elifesciences.org elifesciences.org
    Downregulation of Dickkopf-3, a Wnt antagonist elevated in Alzheimer's disease, restores synapse integrity and memory in a disease mouse model
    2
    1. scibot 01 Mar 2024
      RRID: AB_2564653

      DOI: 10.7554/eLife.89453

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    2. scibot 01 Mar 2024
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      DOI: 10.7554/eLife.89453

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    elifesciences.org/articles/89453
  4. Feb 2024
  5. www.sciencedirect.com www.sciencedirect.com
    Familial Alzheimer mutations stabilize synaptotoxic γ-secretase-substrate complexes
    1
    1. scibot 14 Feb 2024
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      DOI: 10.1016/j.celrep.2024.113761

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    sciencedirect.com/science/article/pii/S2211124724000895
  6. Nov 2023
  7. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A genetic variant of the Wnt receptor LRP6 accelerates synapse degeneration during aging and in Alzheimer’s disease
    1
    1. scibot 09 Nov 2023
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      DOI: 10.1126/sciadv.abo7421

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    ncbi.nlm.nih.gov/pmc/articles/PMC10624429/
  8. Sep 2023
  9. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Endothelial senescence alleviates cognitive impairment in a mouse model of Alzheimer's disease
    1
    1. scibot 07 Sep 2023
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      DOI: 10.1002/glia.24461

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    onlinelibrary.wiley.com/doi/10.1002/glia.24461
  10. www.sciencedirect.com www.sciencedirect.com
    Genetic variants of phospholipase C-γ2 alter the phenotype and function of microglia and confer differential risk for Alzheimer’s disease
    1
    1. scibot 07 Sep 2023
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      DOI: 10.1016/j.immuni.2023.08.008

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    sciencedirect.com/science/article/pii/S1074761323003643
  11. Aug 2023
  12. 52.53.155.43 52.53.155.43
    PIIS2211124723009671-html.html
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    1. scibot 18 Aug 2023
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      DOI: 10.1016/j.celrep.2023.112956

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    52.53.155.43/0930b1a126a7ba8f04174ca993466b0fe3a7955f/PIIS2211124723009671-html.html
  13. Jul 2023
  14. www.sciencedirect.com www.sciencedirect.com
    Evidence for a clathrin-independent endocytic pathway for APP internalization in the neuronal somatodendritic compartment
    1
    1. scibot 13 Jul 2023
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      DOI: 10.1016/j.celrep.2023.112774

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    sciencedirect.com/science/article/pii/S2211124723007854
  15. www.sciencedirect.com www.sciencedirect.com
    Hepatic soluble epoxide hydrolase activity regulates cerebral Aβ metabolism and the pathogenesis of Alzheimer’s disease in mice
    1
    1. scibot 06 Jul 2023
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      DOI: 10.1016/j.neuron.2023.06.002

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    sciencedirect.com/science/article/pii/S0896627323004373
  16. May 2023
  17. 52.53.155.43 52.53.155.43
    Emx1-Cre-mediated inactivation of PDK1 prevents plaque deposition in an Alzheimer’s disease-like mouse model
    1
    1. scibot 04 May 2023
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      DOI: 10.36922/an.v1i3.153

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    52.53.155.43/438598aeab07baaec772d6c22da43b4baf80f7c8/202211301546121b45a6671-html.html
  18. Apr 2023
  19. www.sciencedirect.com www.sciencedirect.com
    Oxytocin attenuates microglial activation and restores social and non-social memory in APP/PS1 Alzheimer model mice
    1
    1. scibot 21 Apr 2023
      RRID:AB_2564653

      DOI: 10.1016/j.isci.2023.106545

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    sciencedirect.com/science/article/pii/S2589004223006223
  20. Mar 2023
  21. www.biorxiv.org www.biorxiv.org
    Genetic Variants of Phospholipase C-γ2 Confer Altered Microglial Phenotypes and Differential Risk for Alzheimer’s Disease
    1
    1. scibot 23 Mar 2023
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      DOI: 10.1101/2022.12.08.519685

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    biorxiv.org/content/10.1101/2022.12.08.519685v1
  22. www.sciencedirect.com www.sciencedirect.com
    INPP5D expression is associated with risk for Alzheimer's disease and induced by plaque-associated microglia
    1
    1. scibot 18 Mar 2023
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      DOI: 10.1016/j.nbd.2021.105303

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    sciencedirect.com/science/article/pii/S0969996121000528
  23. Jan 2023
  24. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Microglial Expression of the Wnt Signaling Modulator DKK2 Differs between Human Alzheimer’s Disease Brains and Mouse Neurodegeneration Models
    1
    1. scibot 18 Jan 2023
      RRID:AB_2564653

      DOI: 10.1523/ENEURO.0306-22.2022

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    ncbi.nlm.nih.gov/pmc/articles/PMC9836029/
  25. Dec 2022
  26. link.springer.com link.springer.com
    Cognitively impaired aged Octodon degus recapitulate major neuropathological features of sporadic Alzheimer’s disease
    1
    1. scibot 20 Dec 2022
      AB_2564653

      DOI: 10.1186/s40478-022-01481-x

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    link.springer.com/article/10.1186/s40478-022-01481-x
  27. Sep 2022
  28. www.sciencedirect.com www.sciencedirect.com
    Association of B cell profile and receptor repertoire with the progression of Alzheimer’s disease
    1
    1. scibot 21 Sep 2022
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      DOI: 10.1016/j.celrep.2022.111391

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    sciencedirect.com/science/article/pii/S2211124722012281
  29. www.sciencedirect.com www.sciencedirect.com
    A next-generation iPSC-derived forebrain organoid model of tauopathy with tau fibrils by AAV-mediated gene transfer
    1
    1. scibot 11 Sep 2022
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      DOI: 10.1016/j.crmeth.2022.100289

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    sciencedirect.com/science/article/pii/S2667237522001710
  30. Aug 2022
  31. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Genetic Inhibition of PDK1 Robustly Reduces Plaque Deposition and Ameliorates Gliosis in the 5×FAD Mouse Model of Alzheimer’s Disease
    1
    1. scibot 11 Aug 2022
      RRID:AB_2564653

      DOI: 10.1111/nan.12839

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    onlinelibrary.wiley.com/doi/10.1111/nan.12839
  32. Jun 2022
  33. 52.53.155.43 52.53.155.43
    The bidirectional lung brain-axis of amyloid-β pathology: ozone dysregulates the peri-plaque microenvironment
    1
    1. scibot 22 Jun 2022
      RRID:AB_2564653

      DOI: 10.1093/brain/awac113

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    52.53.155.43/6c7269a8a0c4cf96641f05a6f51be2d6d8c4ab00/awac113 (1)-html.html
  34. 52.53.155.43 52.53.155.43
    awac113-html.html
    1
    1. scibot 18 Jun 2022
      RRID:AB_2564653

      DOI: 10.1093/brain/awac113

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    52.53.155.43/30a61ebc09dbd539ad43de2662708a6ef00e0754/awac113-html.html
  35. May 2022
  36. aacrjournals.org aacrjournals.org
    Melanoma-secreted Amyloid Beta Suppresses Neuroinflammation and Promotes Brain Metastasis
    1
    1. scibot 13 May 2022
      RRID:AB_25643453

      DOI: 10.1158/2159-8290.CD-21-1006

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    aacrjournals.org/cancerdiscovery/article/12/5/1314/694563/Melanoma-Secreted-Amyloid-Beta-Suppresses
  37. Mar 2022
  38. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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    1. scibot 22 Mar 2022
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      DOI: 10.1111/bph.14688

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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.14688
  39. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Aquaporin 4 deficiency eliminates the beneficial effects of voluntary exercise in a mouse model of Alzheimer's disease
    1
    1. scibot 11 Mar 2022
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      DOI: 10.4103/1673-5374.335169

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    ncbi.nlm.nih.gov/pmc/articles/PMC8848602/
  40. www.sciencedirect.com www.sciencedirect.com
    Lipid flippase dysfunction as a therapeutic target for endosomal anomalies in Alzheimer’s disease
    1
    1. scibot 02 Mar 2022
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      DOI: 10.1016/j.isci.2022.103869

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    sciencedirect.com/science/article/pii/S2589004222001390
  41. Feb 2022
  42. www.sciencedirect.com www.sciencedirect.com
    Neuropeptide signaling and SKN-1 orchestrate differential responses of the proteostasis network to dissimilar proteotoxic insults
    2
    1. scibot 11 Feb 2022
      RRID:AB_2564653

      DOI: 10.1016/j.celrep.2022.110350

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    2. scibot 09 Feb 2022
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      DOI: 10.1016/j.celrep.2022.110350

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    sciencedirect.com/science/article/pii/S2211124722000663
  43. Jan 2022
  44. www.sciencedirect.com www.sciencedirect.com
    Early derailment of firing properties in CA1 pyramidal cells of the ventral hippocampus in an Alzheimer's disease mouse model
    1
    1. scibot 27 Jan 2022
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      DOI: 10.1016/j.expneurol.2021.113969

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    sciencedirect.com/science/article/pii/S0014488621003770
  45. Nov 2021
  46. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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    1. scibot 23 Nov 2021
      RRID:AB_2564653

      DOI: 10.1111/bph.15691

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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15691
  47. Oct 2021
  48. www.sciencedirect.com www.sciencedirect.com
    Vitamin B12 impacts amyloid beta-induced proteotoxicity by regulating the methionine/S-adenosylmethionine cycle
    1
    1. scibot 01 Oct 2021
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      DOI: 10.1016/j.celrep.2021.109753

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    sciencedirect.com/science/article/pii/S2211124721012079
  49. Sep 2021
  50. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cytosolic aggregation of mitochondrial proteins disrupts cellular homeostasis by stimulating the aggregation of other proteins
    1
    1. scibot 28 Sep 2021
      RRID:AB_2564653803001

      DOI: 10.7554/eLife.65484

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    ncbi.nlm.nih.gov/pmc/articles/PMC8457837/
  51. Aug 2021
  52. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    iPSC-derived human microglia-like cells to study neurological diseases
    1
    1. scibot 13 Aug 2021
      RRID:AB_2564653

      DOI: 10.1016/j.neuron.2017.03.042

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    ncbi.nlm.nih.gov/pmc/articles/PMC5482419/
  53. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Untitled document
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      DOI: 10.1016/j.celrep.2018.11.095

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    ncbi.nlm.nih.gov/pmc/articles/PMC6315085/
  54. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Untitled document
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      DOI: 10.1111/jnc.14251

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    ncbi.nlm.nih.gov/pmc/articles/PMC5846890/
  55. Jul 2021
  56. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Untitled document
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    1. scibot 31 Jul 2021
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      DOI: 10.1111/jnc.14251

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    onlinelibrary.wiley.com/doi/full/10.1111/jnc.14251
  57. www.nature.com www.nature.com
    Dopamine neuronal loss contributes to memory and reward dysfunction in a model of Alzheimer’s disease
    2
    1. scibot 27 Jul 2021
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      DOI: 10.1038/ncomms14727

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      DOI: 10.1038/ncomms14727

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    nature.com/articles/ncomms14727
  58. Jun 2021
  59. www.sciencedirect.com www.sciencedirect.com
    SORL1 deficiency in human excitatory neurons causes APP-dependent defects in the endolysosome-autophagy network
    1
    1. scibot 16 Jun 2021
      RRID:AB_2564653

      DOI: 10.1016/j.celrep.2021.109259

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    sciencedirect.com/science/article/pii/S2211124721006239
  60. www.sciencedirect.com www.sciencedirect.com
    PSD-95 protects synapses from β-amyloid
    1
    1. scibot 02 Jun 2021
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      DOI: 10.1016/j.celrep.2021.109194

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    sciencedirect.com/science/article/pii/S2211124721005404
  61. Mar 2021
  62. www.sciencedirect.com www.sciencedirect.com
    Nilotinib restores memory function by preventing dopaminergic neuron degeneration in a mouse model of Alzheimer’s Disease
    1
    1. scibot 09 Mar 2021
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      DOI: 10.1016/j.pneurobio.2021.102031

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    sciencedirect.com/science/article/pii/S0301008221000459
  63. Feb 2021
  64. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Limiting RyR2 Open Time Prevents Alzheimer’s Disease-Related Neuronal Hyperactivity and Memory Loss but Not β-Amyloid Accumulation
    1
    1. scibot 26 Feb 2021
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      DOI: 10.1016/j.celrep.2020.108169

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  65. www.mdpi.com www.mdpi.com
    Peptide Interference with APP and Tau Association: Relevance to Alzheimer’s Disease Amelioration
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      DOI: 10.3390/ijms21093270

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  66. Oct 2020
  67. www.jneurosci.org www.jneurosci.org
    14,15-epoxyeicosatrienoic acid alleviates pathology in a mouse model of Alzheimer’s disease
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      DOI: 10.1523/JNEUROSCI.1246-20.2020

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  68. Sep 2020
  69. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Limiting RyR2 Open Time Prevents Alzheimer’s Disease-Related Neuronal Hyperactivity and Memory Loss but Not β-Amyloid Accumulation
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    1. scibot 25 Sep 2020
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  70. elifesciences.org elifesciences.org
    Opposite changes in APP processing and human Aβ levels in rats carrying either a protective or a pathogenic APP mutation
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      DOI: 10.7554/eLife.52612

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  71. www.jneurosci.org www.jneurosci.org
    A role of low-density lipoprotein receptor-related protein 4 (LRP4) in astrocytic Aβ clearance
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      DOI: 10.1523/JNEUROSCI.0250-20.2020

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  72. alzres.biomedcentral.com alzres.biomedcentral.com
    A selective p38α/β MAPK inhibitor alleviates neuropathology and cognitive impairment, and modulates microglia function in 5XFAD mouse
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      DOI: 10.1186/s13195-020-00617-2

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  73. faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com
    Extracellular vesicles: where the amyloid precursor protein carboxyl‐terminal fragments accumulate and amyloid‐β oligomerizes
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      DOI: 10.1096/fj.202000823R

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  74. link.springer.com link.springer.com
    Increased levels of Stress-inducible phosphoprotein-1 accelerates amyloid-β deposition in a mouse model of Alzheimer’s disease
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      anti-β-amyloid

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  75. Jan 2020
  76. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mechanisms of hyperexcitability in Alzheimer’s disease hiPSC-derived neurons and cerebral organoids vs isogenic controls
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      DOI: 10.7554/eLife.50333

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  77. www.sciencedirect.com www.sciencedirect.com
    Deep Multilayer Brain Proteomics Identifies Molecular Networks in Alzheimer’s Disease Progression
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      DOI: 10.1016/j.neuron.2019.12.015

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  78. www.sciencedirect.com www.sciencedirect.com
    Neuronal XBP-1 Activates Intestinal Lysosomes to Improve Proteostasis in C. elegans
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      DOI: 10.1016/j.cub.2019.06.031

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    sciencedirect.com/science/article/pii/S0960982219307584
  79. www.sciencedirect.com www.sciencedirect.com
    A Breakdown in Metabolic Reprogramming Causes Microglia Dysfunction in Alzheimer's Disease
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    1. scibot 13 Jan 2020
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      DOI: 10.1016/j.cmet.2019.06.005

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  80. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    Untitled document
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      DOI: 10.1111/bph.14688

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  81. www.sciencedirect.com www.sciencedirect.com
    Untitled document
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      DOI: 10.1016/j.neuron.2019.01.014

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    sciencedirect.com/science/article/pii/S0896627319300157
  82. www.sciencedirect.com www.sciencedirect.com
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      RRID:AB_2564653

      DOI: 10.1016/j.celrep.2018.11.095

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    sciencedirect.com/science/article/pii/S2211124718318862
  83. onlinelibrary.wiley.com onlinelibrary.wiley.com
    A novel crosslinking protocol stabilizes amyloid β oligomers capable of inducing Alzheimer's‐associated pathologies
    1
    1. scibot 12 Jan 2020
      RRID:AB_2564653

      DOI: 10.1111/jnc.14647

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  84. Nov 2018
  85. www.sciencedirect.com www.sciencedirect.com
    Age-Dependent Effects of apoE Reduction Using Antisense Oligonucleotides in a Model of β-amyloidosis
    1
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    sciencedirect.com/science/article/pii/S089662731731067X
  86. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Longitudinal investigation of neuroinflammation and metabolite profiles in the APPswe×PS1Δe9 transgenic mouse model of Alzheimer's disease
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    onlinelibrary.wiley.com/doi/10.1111/jnc.14251/full
  87. Nov 2017
  88. onlinelibrary.wiley.com onlinelibrary.wiley.com
    A human scFv antibody that targets and neutralizes high molecular weight pathogenic amyloid‐β oligomers
    1
    1. scibot 08 Nov 2017
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      Curator: @patriciaelyse_

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    onlinelibrary.wiley.com/doi/10.1111/jnc.14118/full
  89. www.sciencedirect.com www.sciencedirect.com
    iPSC-Derived Human Microglia-like Cells to Study Neurological Diseases
    1
    1. scibot 08 Nov 2017
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      Curator: @kaitlinsung

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    sciencedirect.com/science/article/pii/S0896627317302866
  90. www.jneurosci.org www.jneurosci.org
    Regulation of Synaptic Amyloid-β Generation through BACE1 Retrograde Transport in a Mouse Model of Alzheimer's Disease
    1
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      Curator: @chewbeccax

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    jneurosci.org/content/37/10/2639.long