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40 Matching Annotations

Dec 2025
www.sciencedirect.com:5037 www.sciencedirect.com:5037

γ-Secretase exosites as targets for substrate-selective lowering of Aβ generation

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  DOI: 10.1016/j.str.2025.11.010
  
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sciencedirect.com:5037/science/article/pii/S0969212625004447
Nov 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Progressive remote memory decline coincides with parvalbumin interneuron hyperexcitability and enhanced inhibition of cortical engram cells in a mouse model of Alzheimer’s disease

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  DOI: 10.7554/eLife.106866
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12638044/
Oct 2025
www.sciencedirect.com www.sciencedirect.com

Single-nucleus RNA sequencing reveals GABAergic vulnerability and reactive gliosis driven by loss of TDP-43

1
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  DOI: 10.1016/j.isci.2025.113745
  
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sciencedirect.com/science/article/pii/S2589004225020061
onlinelibrary.wiley.com onlinelibrary.wiley.com

Polyglucosan body disease in an aged chimpanzee (Pan troglodytes)

1
1. scibot 04 Oct 2025
  
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  DOI: 10.1111/neup.12906
  
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onlinelibrary.wiley.com/doi/10.1111/neup.12906
Mar 2025
www.sciencedirect.com www.sciencedirect.com

Enhanced social interaction protects cognition by preserving synapse numbers

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  DOI: 10.1016/j.brainres.2025.149552
  
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sciencedirect.com/science/article/pii/S0006899325001106
Nov 2024
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Imbalance in glucose metabolism regulates the transition of microglia from homeostasis to Disease Associated Microglia stage 1

1
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  DOI: 10.1523/JNEUROSCI.1563-23.2024
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11097271/
Sep 2024
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Histone Deacetylases 1 and 2 Regulate Microglia Function during Development, Homeostasis, and Neurodegeneration in a Context-Dependent Manner

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  RRID:AB_2564653
  
  DOI: 10.1016/j.immuni.2018.02.016
  
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sciencedirect.com/science/article/pii/S107476131830075X
Aug 2024
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<em>Neuropathology and Applied Neurobiology</em> | BNS Journal | Wiley Online Library

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  DOI: 10.1111/nan.12991
  
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onlinelibrary.wiley.com/doi/10.1111/nan.12991
Apr 2024
52.53.155.43 52.53.155.43

JNEUROSCI.1563-23.2024.full (1)-html.html

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52.53.155.43/3d13c66ed91f2e0714f85e7c6a7de97c0df74a89/JNEUROSCI.1563-23.2024.full (1)-html.html
Dec 2023
onlinelibrary.wiley.com onlinelibrary.wiley.com

Leakage beyond the primary lesion: A temporal analysis of cerebrovascular dysregulation at sites of hippocampal secondary neurodegeneration following cortical photothrombotic stroke

1
1. scibot 01 Dec 2023
  
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onlinelibrary.wiley.com/doi/10.1111/jnc.16008
Oct 2023
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Modification of astrocytic Cx43 hemichannel activity in animal models of AD: modulation by adenosine A2A receptors

1
1. scibot 31 Oct 2023
  
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  DOI: 10.1007/s00018-023-04983-6
  
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pmc.ncbi.nlm.nih.gov/articles/PMC10613596/
Jul 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Long-term radiofrequency electromagnetic fields exposure attenuates cognitive dysfunction in 5×FAD mice by regulating microglial function

1
1. scibot 25 Jul 2023
  
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  DOI: 10.4103/1673-5374.371379
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10360091/
Jun 2023
52.53.155.43 52.53.155.43

Apolipoprotein E intersects with amyloid-β within neurons

2
1. scibot 24 Jun 2023
  
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  DOI: 10.26508/lsa.202201887
  
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  DOI: 10.26508/lsa.202201887
  
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52.53.155.43/d79c74abbe0299455dfcf8568ff6bf527c1e5b68/e202201887.full-html.html
Apr 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

INPP5D modulates TREM2 loss-of-function phenotypes in a β-amyloidosis mouse model

1
1. scibot 09 Apr 2023
  
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  DOI: 10.1016/j.isci.2023.106375
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10074152/
Feb 2023
www.sciencedirect.com www.sciencedirect.com

Aberrant serotonergic signaling contributes to the hyperexcitability of CA1 pyramidal neurons in a mouse model of Alzheimer’s disease

1
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  DOI: 10.1016/j.celrep.2023.112152
  
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sciencedirect.com/science/article/pii/S2211124723001638
Aug 2022
europepmc.org europepmc.org

Reduced HGF/MET Signaling May Contribute to the Synaptic Pathology in an Alzheimer's Disease Mouse Model.

1
1. scibot 08 Aug 2022
  
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  DOI: 10.3389/fnagi.2022.954266
  
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europepmc.org/article/MED/35903536
May 2022
www.sciencedirect.com www.sciencedirect.com

Aβ oligomer concentration in mouse and human brain and its drug-induced reduction ex vivo

1
1. scibot 19 May 2022
  
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  DOI: 10.1016/j.xcrm.2022.100630
  
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sciencedirect.com/science/article/pii/S2666379122001550
Mar 2022
onlinelibrary.wiley.com onlinelibrary.wiley.com

Astrocytic changes with aging and Alzheimer's disease-type pathology in chimpanzees

1
1. scibot 31 Mar 2022
  
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  RRID:AB_2313952
  
  DOI: 10.1002/cne.24610
  
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onlinelibrary.wiley.com/doi/10.1002/cne.24610
www.sciencedirect.com www.sciencedirect.com

Positive feedback regulation of microglial glucose metabolism by histone H4 lysine 12 lactylation in Alzheimer’s disease

1
1. scibot 27 Mar 2022
  
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  DOI: 10.1016/j.cmet.2022.02.013
  
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sciencedirect.com/science/article/pii/S1550413122000857
journals.lww.com journals.lww.com

DNA vaccines targeting amyloid-β oligomer ameliorate... : Neural Regeneration Research

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  RRID:AB_201061
  
  DOI: 10.4103/1673-5374.337054
  
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journals.lww.com/nrronline/Fulltext/2022/10000/DNA_vaccines_targeting_amyloid___oligomer.42.aspx
Jan 2022
onlinelibrary.wiley.com onlinelibrary.wiley.com

Detection and Quantification of Aβ−3–40 (APP669-711) in Cerebrospinal Fluid

1
1. scibot 22 Jan 2022
  
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  DOI: 10.1111/jnc.15571
  
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onlinelibrary.wiley.com/doi/10.1111/jnc.15571
Nov 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

NHE6 depletion corrects ApoE4-mediated synaptic impairments and reduces amyloid plaque load

1
1. scibot 05 Nov 2021
  
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  DOI: 10.7554/eLife.72034
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8547963/
Oct 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Synthetic amyloid-β oligomers drive early pathological progression of Alzheimer’s disease in nonhuman primates

1
1. scibot 28 Oct 2021
  
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  DOI: 10.1016/j.isci.2021.103207
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8524197/
Aug 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

BAD-mediated neuronal apoptosis and neuroinflammation contribute to Alzheimer's disease pathology

1
1. scibot 25 Aug 2021
  
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  DOI: 10.1016/j.isci.2021.102942
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8369003/
May 2021
onlinelibrary.wiley.com onlinelibrary.wiley.com

Hippocampal hyperactivity in a rat model of Alzheimer’s disease

1
1. scibot 20 May 2021
  
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  DOI: 10.1111/jnc.15323
  
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onlinelibrary.wiley.com/doi/10.1111/jnc.15323
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Neuronal pentraxin 1: A synaptic-derived plasma biomarker in Alzheimer's disease

1
1. scibot 12 May 2021
  
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  DOI: 10.1016/j.nbd.2018.02.014
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8092920/
Feb 2021
onlinelibrary.wiley.com onlinelibrary.wiley.com

Remodeling of projections from ventral hippocampus to prefrontal cortex in Alzheimer's mice

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  DOI: 10.1002/cne.25032
  
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onlinelibrary.wiley.com/doi/10.1002/cne.25032
onlinelibrary.wiley.com onlinelibrary.wiley.com

Gut microbiota regulate cognitive deficits and amyloid deposition in a model of Alzheimer’s disease

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1. scibot 25 Feb 2021
  
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  DOI: 10.1111/jnc.15031
  
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onlinelibrary.wiley.com/doi/10.1111/jnc.15031
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Alzheimer’s Protection Effect of A673T Mutation May Be Driven by Lower Aβ Oligomer Binding Affinity

1
1. scibot 24 Feb 2021
  
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  RRID:s:AB_662798
  
  DOI: 10.1111/jnc.15212
  
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onlinelibrary.wiley.com/doi/10.1111/jnc.15212
Nov 2020
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Alzheimer’s Protection Effect of A673T Mutation May Be Driven by Lower Aβ Oligomer Binding Affinity

1
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  DOI: 10.1111/jnc.15212
  
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onlinelibrary.wiley.com/doi/10.1111/jnc.15212
Sep 2020
link.springer.com link.springer.com

Quantification of neurons in the hippocampal formation of chimpanzees: comparison to rhesus monkeys and humans

1
1. scibot 23 Sep 2020
  
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  RRID:AB_662798
  
  DOI: 10.1007/s00429-020-02139-x
  
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link.springer.com/article/10.1007/s00429-020-02139-x
elifesciences.org elifesciences.org

A non-mosaic transchromosomic mouse model of Down syndrome carrying the long arm of human chromosome 21

1
1. scibot 16 Sep 2020
  
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  DOI: 10.7554/eLife.56223
  
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elifesciences.org/articles/56223
www.sciencedirect.com www.sciencedirect.com

Caspase Activation and Caspase-Mediated Cleavage of APP Is Associated with Amyloid β-Protein-Induced Synapse Loss in Alzheimer’s Disease

1
1. scibot 06 Sep 2020
  
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  RRID:AB_662798
  
  DOI: 10.1016/j.celrep.2020.107839
  
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sciencedirect.com/science/article/pii/S2211124720308202
onlinelibrary.wiley.com onlinelibrary.wiley.com

Amyloidosis is associated with thicker myelin and increased oligodendrogenesis in the adult mouse brain

1
1. scibot 06 Sep 2020
  
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  DOI: 10.1002/jnr.24672
  
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onlinelibrary.wiley.com/doi/10.1002/jnr.24672
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Tau is not necessary for amyloid-beta-induced synaptic and memory impairments

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  anti-human Aβ monoclonal
  
  DOI: 10.1172/JCI137040
  
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  Curator comments: Anti-beta-Amyloid Purified (SIGNET) Monoclonal Antibody, Unconjugated, Clone 6E10 Covance Cat# SIG-39320
  
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Microglia changes associated to Alzheimer’s disease pathology in aged chimpanzees

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  RRID:AB_2313952
  
  DOI: 10.1002/cne.24484
  
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Neuromodulatory action of picomolar extracellular Aβ42 oligomers on pre- and postsynaptic mechanisms underlying synaptic function and memory

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  DOI: 10.1523/JNEUROSCI.0163-19.2019
  
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jneurosci.org/content/39/30/5986
Nov 2018
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Neuronal pentraxin 1: A synaptic-derived plasma biomarker in Alzheimer's disease

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Aging African green monkeys manifest transcriptional, pathological, and cognitive hallmarks of human Alzheimer's disease

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  RRID:AB_662798
  
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