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Mitochondrial DNA abundance is a determinant of immunogenic cell death in cancer

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1. scibot 05 Nov 2026
  
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  DOI: 10.1016/j.immuni.2026.10.002
  
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sciencedirect.com/science/article/pii/S1074761326004292
Oct 2026
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Oncolytic Herpes Virus G47Δ Potentiates ADCC-Inducing Molecular Targeted Therapy via Coordinated Activation of Innate and Adaptive Immune Responses

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1. scibot 12 Oct 2026
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13631497/
Sep 2026
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The long non-coding RNA-encoded microprotein MKKS3 drives colorectal cancer chemoresistance

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1. scibot 12 Sep 2026
  
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  DOI: 10.1038/s12276-026-01817-w
  
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nature.com/articles/s12276-026-01817-w
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Strong sustained type I IFN signaling acts cell intrinsically to impair IFNγ responses and cause tuberculosis susceptibility

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1. scibot 02 Sep 2026
  
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  DOI: 10.1016/j.chom.2026.07.014
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13528601/
Jul 2026
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B cell-derived type I interferon sustains T cell functionality upon strong TCR stimulation during chronic infection

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1. scibot 06 Jul 2026
  
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  DOI: 10.1016/j.immuni.2026.06.003
  
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sciencedirect.com/science/article/pii/S1074761326002542
Jun 2026
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Analysis of West Nile disease convalescents identifies human monoclonal antibodies protective against West Nile and related orthoflaviviruses

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1. scibot 25 Jun 2026
  
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  DOI: 10.1016/j.immuni.2026.05.013
  
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sciencedirect.com/science/article/pii/S1074761326002244
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Mrgpra2+ neutrophils integrate infection-derived signals to trigger NET-mediated antimicrobial defense in bone marrow

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1. scibot 25 Jun 2026
  
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  DOI: 10.1016/j.celrep.2026.117579
  
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sciencedirect.com/science/article/pii/S2211124726006571
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Type I interferon signaling in hematopoietic cells impairs neutrophil antibacterial function in the middle ear during viral co-infection

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1. scibot 04 Jun 2026
  
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  DOI: 10.1016/j.xcrm.2026.102846
  
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sciencedirect.com/science/article/pii/S2666379126002636
May 2026
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Maternal-fetal type I interferon signaling drives TREM2 dysregulation and synaptic dysfunction in neurodevelopmental disorders

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1. scibot 29 May 2026
  
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  DOI: 10.1016/j.neuron.2026.04.043
  
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sciencedirect.com/science/article/pii/S0896627326003387
Apr 2026
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A universal boosting strategy for adoptive T cell therapy using a paired vaccine/chimeric antigen receptor

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1. scibot 23 Apr 2026
  
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  DOI: 10.1158/2326-6066.CIR-25-0070
  
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aacrjournals.org/cancerimmunolres/article/14/2/261/771969/A-Universal-Boosting-Strategy-for-Adoptive-T-cell
Mar 2026
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Radiotherapy synergizes with an inducible AAV-based immunotherapy platform to program local and systemic antitumor immunity

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1. scibot 24 Mar 2026
  
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  DOI: 10.1016/j.ccell.2026.02.013
  
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sciencedirect.com/science/article/pii/S153561082600111X
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6-Hydroxydopamine promotes antitumor immunity through macrophage remodeling beyond sympathetic ablation

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1. scibot 20 Mar 2026
  
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  DOI: 10.1016/j.neuron.2026.02.028
  
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sciencedirect.com/science/article/pii/S0896627326001339
Jan 2026
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A type I interferon-mitochondrial axis regulates efferocytosis and interferon-stimulated gene induction in macrophages

1
1. scibot 29 Jan 2026
  
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  DOI: 10.1016/j.immuni.2025.12.010
  
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p57 increases immunotherapy efficacy by promoting cGAS-STING-mediated innate sensing in hepatocellular carcinoma

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1. scibot 09 Jan 2026
  
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  DOI: 10.1016/j.celrep.2025.116769
  
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sciencedirect.com/science/article/pii/S2211124725015414
Dec 2025
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Distinct components of mRNA vaccines cooperate to instruct efficient germinal center responses

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1. scibot 17 Dec 2025
  
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  DOI: 10.1016/j.cell.2025.11.023
  
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sciencedirect.com:5037/science/article/pii/S0092867425013583
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Olaparib and radiotherapy induce type I interferon and CD8+ T cell-dependent sensitization to immunotherapy in pancreatic cancer

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1. scibot 05 Dec 2025
  
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  DOI: 10.1158/1535-7163.MCT-24-0210
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12137021/
Nov 2025
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Virus envelope glycoprotein targeting bispecific T cell engager protects mice from lethal severe fever with thrombocytopenia virus infection

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1. scibot 22 Nov 2025
  
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  RRID:AB_2687723
  
  DOI: 10.1016/j.xcrm.2025.102458
  
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sciencedirect.com/science/article/pii/S2666379125005312
Oct 2025
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Super-adjuvant nanoparticles for platform cancer vaccination

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1. scibot 15 Oct 2025
  
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  DOI: 10.1016/j.xcrm.2025.102415
  
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sciencedirect.com/science/article/pii/S2666379125004884
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In situ extended immune activation instantly after tumor resection by oncolytic virus controls postoperative tumor recurrence

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1. scibot 08 Oct 2025
  
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  DOI: 10.1016/j.xcrm.2025.102399
  
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sciencedirect.com/science/article/pii/S2666379125004720
Sep 2025
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ZBP1 pathway promotes tumor immunogenicity in the combination of anti-HER2 therapy and epigenetic therapy

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1. scibot 17 Sep 2025
  
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  DOI: 10.1016/j.celrep.2025.116314
  
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sciencedirect.com/science/article/pii/S221112472501085X
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Innate immune sensing of Z-nucleic acids by ZBP1-RIPK1 axis drives neuroinflammation in Alzheimer’s disease

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1. scibot 03 Sep 2025
  
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  DOI: 10.1016/j.immuni.2025.07.024
  
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sciencedirect.com/science/article/pii/S1074761325003334
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Cancer cell and microenvironmental rewiring by ADAR1 loss impairs glioblastoma tumor growth and extends survival

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1. scibot 03 Sep 2025
  
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  DOI: 10.1016/j.celrep.2025.116151
  
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sciencedirect.com/science/article/pii/S2211124725009222
Aug 2025
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Macrophages orchestrate elimination of Shigella from the intestinal epithelial cell niche via TLR-induced IL-12 and IFN-γ

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1. scibot 30 Aug 2025
  
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  RRID:AB_2687723
  
  DOI: 10.1016/j.chom.2025.08.001
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12471108/
Jul 2025
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Targeting Intracellular Innate RNA-Sensing Systems Overcomes Resistance to CAR T-cell Therapy in Solid Tumors

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1. scibot 17 Jul 2025
  
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  DOI: 10.1158/0008-5472.CAN-24-3425
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12260516/
Jun 2025
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Interferon-epsilon, an estrogen-induced type I interferon, is uniquely exploited by Neisseria gonorrhoeae via effects on sialic acid metabolism

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1. scibot 11 Jun 2025
  
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  DOI: 10.1016/j.chom.2025.05.015
  
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sciencedirect.com/science/article/pii/S1931312825001982
Feb 2025
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Nanoparticle delivery of innate immune agonists combined with senescence-inducing agents promotes T cell control of pancreatic cancer

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1. scibot 13 Feb 2025
  
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  DOI: 10.1126/scitranslmed.adj9366
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11811823/
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Mechanistic insight into the induction of liver tissue-resident memory CD8+ T cells by glycolipid-peptide vaccination

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1. scibot 13 Feb 2025
  
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  DOI: 10.1016/j.celrep.2025.115295
  
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sciencedirect.com/science/article/pii/S221112472500066X
Nov 2024
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Type III interferons induce pyroptosis in gut epithelial cells and impair mucosal repair

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1. scibot 16 Nov 2024
  
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  DOI: 10.1016/j.cell.2024.10.010
  
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Targeting Catechol-O-Methyltransferase Induces Mitochondrial Dysfunction and Enhances the Efficacy of Radiotherapy in Glioma

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1. scibot 08 Nov 2024
  
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  DOI: 10.1158/0008-5472.CAN-24-0134
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11532787/
Jul 2024
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VHL loss enhances antitumor immunity by activating the anti-viral DNA-sensing pathway

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1. scibot 27 Jul 2024
  
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  DOI: 10.1016/j.isci.2024.110285
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11267025/
Jun 2024
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Opposing tumor-cell-intrinsic and -extrinsic roles of the IRF1 transcription factor in antitumor immunity

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1. scibot 04 Jun 2024
  
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  DOI: 10.1016/j.celrep.2024.114289
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11315447/
Apr 2024
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Squalene-epoxidase-catalyzed 24(S),25-epoxycholesterol synthesis promotes trained-immunity-mediated antitumor activity

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1. scibot 18 Apr 2024
  
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  DOI: 10.1016/j.celrep.2024.114094
  
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2. scibot 18 Apr 2024
  
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  DOI: 10.1016/j.celrep.2024.114094
  
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sciencedirect.com/science/article/pii/S2211124724004224
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Type I interferons induce an epigenetically distinct memory B cell subset in chronic viral infection

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1. scibot 09 Apr 2024
  
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  DOI: 10.1016/j.immuni.2024.03.016
  
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sciencedirect.com/science/article/pii/S1074761324001377
Jan 2024
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Interferon-stimulated neutrophils as a predictor of immunotherapy response

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1. scibot 09 Jan 2024
  
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  RRID:AB_2687723
  
  DOI: 10.1016/j.ccell.2023.12.005
  
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Dec 2023
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Reprogramming of tumor-associated macrophages via NEDD4-mediated CSF1R degradation by targeting USP18

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Serotonin reduction in post-acute sequelae of viral infection

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STING signaling promotes NK cell antitumor immunity and maintains a reservoir of TCF-1+ NK cells

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Targeting nucleic acid sensors in tumor cells to reprogram biogenesis and RNA cargo of extracellular vesicles for T cell-mediated cancer immunotherapy

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Targeting TCF19 sensitizes MSI endometrial cancer to anti-PD-1 therapy by alleviating CD8+ T cell exhaustion via TRIM14-IFN-β axis

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Cooperative sensing of mitochondrial DNA by ZBP1 and cGAS promotes cardiotoxicity

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Intravenous heterologous prime-boost vaccination activates innate and adaptive immunity to promote tumor regression

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IFNγ is a central node of cancer immune equilibrium

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Zika virus spreads through infection of lymph node-resident macrophages

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SETDB1 Restrains Endogenous Retrovirus Expression and Antitumor Immunity during Radiotherapy

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Cancer cell-derived type I interferons instruct tumor monocyte polarization

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GPI-Anchored Ligand-BioID2-Tagging System Identifies Galectin-1 Mediating Zika Virus Entry

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Driving axon regeneration by orchestrating neuronal and non-neuronal innate immune responses via the IFNγ-cGAS-STING axis

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The transcription factor IRF2 drives interferon-mediated CD8+ T cell exhaustion to restrict anti-tumor immunity

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Systemic vaccination induces CD8+ T cells and remodels the tumor microenvironment

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BPS Publications

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Concerted type I interferon signaling in microglia and neural cells promotes memory impairment associated with amyloid β plaques

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AXL targeting restores PD-1 blockade sensitivity of STK11/LKB1 mutant NSCLC through expansion of TCF1+ CD8 T cells

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Interferon-β acts directly on T cells to prolong allograft survival by enhancing regulatory T cell induction through Foxp3 acetylation

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MEK inhibition overcomes chemoimmunotherapy resistance by inducing CXCL10 in cancer cells

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ADAR1 restricts ZBP1-mediated immune response and PANoptosis to promote tumorigenesis

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In vivo characterization of emerging SARS-CoV-2 variant infectivity and human antibody escape potential

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Microbiota triggers STING-type I IFN-dependent monocyte reprogramming of the tumor microenvironment

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Untitled document

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Cell-autonomous inflammation of BRCA1-deficient ovarian cancers drives both tumor-intrinsic immunoreactivity and immune resistance via STING

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PARP7 negatively regulates the type I interferon response in cancer cells and its inhibition triggers antitumor immunity

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Interferon-α-producing plasmacytoid dendritic cells drive the loss of adipose tissue regulatory T cells during obesity

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Endogenous retroviruses promote homeostatic and inflammatory responses to the microbiota

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The inhibitory receptor TIM-3 limits activation of the cGAS-STING pathway in intra-tumoral dendritic cells by suppressing extracellular DNA uptake

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Early innate and adaptive immune perturbations determine long-term severity of chronic virus and Mycobacterium tuberculosis coinfection

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DNA Sensing in Mismatch Repair-Deficient Tumor Cells Is Essential for Anti-tumor Immunity

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IL-21/type I interferon interplay regulates neutrophil-dependent innate immune responses to Staphylococcus aureus

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Systemic Inflammation Suppresses Lymphoid Tissue Remodeling and B Cell Immunity during Concomitant Local Infection

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The Unfolded Protein Response Mediator PERK Governs Myeloid Cell-Driven Immunosuppression in Tumors through Inhibition of STING Signaling

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Type I interferon underlies severe disease associated with Junín virus infection in mice

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Blockade of the Phagocytic Receptor MerTK on Tumor-Associated Macrophages Enhances P2X7R-Dependent STING Activation by Tumor-Derived cGAMP

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Untitled document

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Nov 2018
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Gasdermin D Restrains Type I Interferon Response to Cytosolic DNA by Disrupting Ionic Homeostasis

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Non-canonical NF-κB Antagonizes STING Sensor-Mediated DNA Sensing in Radiotherapy

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Self-Renewal and Toll-like Receptor Signaling Sustain Exhausted Plasmacytoid Dendritic Cells during Chronic Viral Infection

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TIM-3 Regulates CD103+ Dendritic Cell Function and Response to Chemotherapy in Breast Cancer

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Dichotomous Expression of TNF Superfamily Ligands on Antigen-Presenting Cells Controls Post-priming Anti-viral CD4+ T Cell Immunity

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