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E-cadherin expression promotes tumor growth via KLRG1-dependent pathways

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1. scibot 28 Apr 2026
  
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  DOI: 10.1093/jimmun/vkag046
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13108842/
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FcRγ-dependent NK cell licensing through CD244 promotes antitumour immunity

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1. scibot 23 Apr 2026
  
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  DOI: 10.1158/2326-6066.CIR-25-0174
  
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aacrjournals.org/cancerimmunolres/article/13/12/2075/768337/FcR-Dependent-NK-Cell-Licensing-through-CD244
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IFNγ-induced PD-L1+MHC II+ macrophages and Tim-3+ tumor-reactive CD8+ T cells predict a response to anti-PD-1 therapy in tumor-bearing mice

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1. scibot 23 Apr 2026
  
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aacrjournals.org/cancerimmunolres/article/13/12/2004/768334/IFN-Induced-PD-L1-MHCII-Macrophages-and-Tim-3
Mar 2026
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Subversion of kynurenine-induced AHR activation in CD8 T cells by kynureninase-expressing antigen-presenting cells

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1. scibot 24 Mar 2026
  
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B cell-intrinsic type I interferon signaling contributes to defective antibody responses to a model antigen during persistent LCMV infection

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In vivo evolution of antibody CR3022 expands cross-neutralization of SARS-CoV-2 variants and informs pan-sarbecovirus immunity

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1. scibot 24 Mar 2026
  
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sciencedirect.com/science/article/pii/S2211124726002159
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Natural maternal immunity protects neonates from Escherichia coli sepsis

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1. scibot 19 Mar 2026
  
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  DOI: 10.1038/s41586-026-10225-z
  
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nature.com/articles/s41586-026-10225-z
Feb 2026
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Polystyrene microplastic-induced pathophysiology is driven by disruption of efferocytosis

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1. scibot 26 Feb 2026
  
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  DOI: 10.1016/j.immuni.2026.01.009
  
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Hyperactivation of sympathetic nerves fuels basophil infiltration in atopic dermatitis

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1. scibot 24 Feb 2026
  
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sciencedirect.com/science/article/pii/S1074761326000312
Jan 2026
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PD-L1 is an intrinsic switch for natural killer cell-mediated, TRAIL-dependent antiviral function

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1. scibot 30 Jan 2026
  
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  DOI: 10.1016/j.celrep.2026.116939
  
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sciencedirect.com/science/article/pii/S2211124726000173
Dec 2025
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Unconventional CD8+ T cell surveillance of cytomegalovirus via Qa-1/HLA-E–restricted epitope recognition

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1. scibot 23 Dec 2025
  
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  DOI: 10.1126/sciadv.aea8707
  
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2. scibot 23 Dec 2025
  
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  DOI: 10.1126/sciadv.aea8707
  
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science.org/doi/10.1126/sciadv.aea8707
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Distinct components of mRNA vaccines cooperate to instruct efficient germinal center responses

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1. scibot 17 Dec 2025
  
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  DOI: 10.1016/j.cell.2025.11.023
  
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Tolerance to ferroptosis facilitates lipid metabolism and pathogenic type 2 immunity in allergic airway inflammation

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1. scibot 11 Dec 2025
  
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  DOI: 10.1016/j.immuni.2025.11.018
  
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Structural basis of microtubule-mediated signal transduction

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1. scibot 09 Dec 2025
  
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  DOI: 10.1016/j.cell.2025.11.011
  
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Immunocompetent murine models recapitulate the heterogeneous tumor immune microenvironment of human liposarcoma

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1. scibot 02 Dec 2025
  
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  DOI: 10.1158/1078-0432.CCR-25-1628
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12664306/
Nov 2025
54.241.53.176 54.241.53.176

jaeckstein-et-al-2025-purinergic-adipocyte-macrophage-crosstalk-promotes-degeneration-of-thermogenic-brown-adipose-html.html

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1. scibot 25 Nov 2025
  
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  DOI: 10.1038/s44319-025-00642-y
  
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54.241.53.176/f747cb2da22a4018614419251bb372fb2280d9d1/jaeckstein-et-al-2025-purinergic-adipocyte-macrophage-crosstalk-promotes-degeneration-of-thermogenic-brown-adipose-html.html
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Mucosal viral infection elicits long-lived IgA responses via type 1 follicular helper T cells

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1. scibot 18 Nov 2025
  
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  DOI: 10.1016/j.cell.2025.07.022
  
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IL-2/IL-15 signaling induces NK cell production of FLT3LG augmenting anti-PD-1 immunotherapy

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1. scibot 06 Nov 2025
  
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  DOI: 10.1158/2326-6066.CIR-24-1259
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12582536/
Sep 2025
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ZBP1 pathway promotes tumor immunogenicity in the combination of anti-HER2 therapy and epigenetic therapy

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  DOI: 10.1016/j.celrep.2025.116314
  
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Phenotypic pleiotropy of missense variants in human B cell confinement receptor P2RY8

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  DOI: 10.1016/j.xgen.2025.100981
  
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IL-25-induced memory type 2 innate lymphoid cells enforce mucosal immunity

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  DOI: 10.1016/j.cell.2025.08.017
  
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sciencedirect.com/science/article/pii/S0092867425009729
Aug 2025
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CD138 and APRIL regulate plasma cell survival, competition, and retention in the bone marrow niche

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1. scibot 06 Aug 2025
  
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  DOI: 10.1016/j.celrep.2025.116123
  
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Mutations in MLL3 promote breast cancer progression via HIF1α-dependent intratumoral recruitment and differentiation of regulatory T cells

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Jul 2025
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Tumor-associated macrophages restrict CD8+ T cell function through collagen deposition and metabolic reprogramming of the breast cancer microenvironment

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  DOI: 10.1038/s43018-024-00775-4
  
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Mutant p53 exploits enhancers to elevate immunosuppressive chemokine expression and impair immune checkpoint inhibitors in pancreatic cancer

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  DOI: 10.1016/j.immuni.2025.06.005
  
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Jun 2025
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Probiotic-mediated tumor microenvironment reprogramming with protease-sensitive interleukin-15 and photothermal therapy

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  DOI: 10.1016/j.xcrm.2025.102191
  
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Single-cell analysis of temporal immune cell dynamics in alopecia areata reveals a causal role for clonally expanded CD8+ T cells in disease

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1. scibot 18 Jun 2025
  
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  DOI: 10.1016/j.celrep.2025.115798
  
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De-coupling immune parameters and toxicity associated with IL-12 agonism

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  DOI: 10.1016/j.celrep.2025.115840
  
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sciencedirect.com/science/article/pii/S2211124725006114
May 2025
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Macrophages direct location-dependent recall of B cell memory to vaccination

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  DOI: 10.1016/j.cell.2025.04.005
  
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sciencedirect.com/science/article/pii/S0092867425004076
Apr 2025
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PD-html.html

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  DOI: 10.1101/2025.03.25.645270
  
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Optimizing stem cell infusion timing in the prevention of acute graft-versus-host disease

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Mar 2025
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Lung-resident memory B cells maintain allergic IgE responses in the respiratory tract

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1. scibot 29 Mar 2025
  
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  DOI: 10.1016/j.immuni.2025.03.001
  
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Ligand-induced ubiquitination unleashes LAG3 immune checkpoint function by hindering membrane sequestration of signaling motifs

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1. scibot 20 Mar 2025
  
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  DOI: 10.1016/j.cell.2025.02.014
  
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sciencedirect.com/science/article/pii/S0092867425001990
Feb 2025
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Tumor cell–intrinsic Piezo2 drives radioresistance by impairing CD8+ T cell stemness maintenance

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1. scibot 26 Feb 2025
  
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  DOI: 10.1084/jem.20231486
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11338319/
Dec 2024
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Durable lymphocyte subset elimination upon a single dose of AAV-delivered depletion antibody dissects immune control of chronic viral infection

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  DOI: 10.1016/j.immuni.2024.11.021
  
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Psoriatic arthritis subtypes are phenocopied in humanized mice

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Aug 2024
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CD4+ T cells reactive to a hybrid peptide from insulin-chromogranin A adopt a distinct effector fate and are pathogenic in autoimmune diabetes

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Jun 2024
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Therapeutic potential of co-signaling receptor modulation in hepatitis B

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May 2024
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Clostridioides difficile toxin B subverts germinal center and antibody recall responses by stimulating a drug-treatable CXCR4-dependent mechanism

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Apr 2024
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Early-life vitamin A treatment rescues neonatal infection-induced durably impaired tolerogenic properties of celiac lymph nodes

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Endothelial cell expression of a STING gain-of-function mutation initiates pulmonary lymphocytic infiltration

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Feb 2024
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The CD27/CD70 pathway negatively regulates visceral adipose tissue-resident Th2 cells and controls metabolic homeostasis

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Cell-intrinsic PD-L1 ablation sustains effector CD8+ T cell responses and promotes antitumor T cell therapy

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A GPCR-neuropeptide axis dampens hyperactive neutrophils by promoting an alternative-like polarization during bacterial infection

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Dec 2023
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Circulating NK cells establish tissue residency upon acute infection of skin and mediate accelerated effector responses to secondary infection

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Nov 2023
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An essential role for miR-15/16 in Treg suppression and restriction of proliferation

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CD300f immune receptor contributes to healthy aging by regulating inflammaging, metabolism, and cognitive decline

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Commensal bacteria signal through TLR5 and AhR to improve barrier integrity and prevent allergic responses to food

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STING signaling promotes NK cell antitumor immunity and maintains a reservoir of TCF-1+ NK cells

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Aug 2023
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Enhancing autophagy in CD11c+ antigen-presenting cells as a therapeutic strategy for acute respiratory distress syndrome

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May 2023
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YTHDF2 inhibition potentiates radiotherapy antitumor efficacy

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Glioblastoma cell fate is differentially regulated by the microenvironments of the tumor bulk and infiltrative margin

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Apr 2023
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T helper 1 effector memory CD4+ T cells protect the skin from poxvirus infection

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Mar 2023
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Assessing in vivo presentation of exogenous antigen in the tumor microenvironment in mice

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Feb 2023
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Circumvention of luteolysis reveals parturition pathways in mice dependent upon innate type 2 immunity

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Jan 2023
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Metabolic adaptation supports enhanced macrophage efferocytosis in limited-oxygen environments

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Neutrophil-activating therapy for the treatment of cancer

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The ectromelia virus virulence factor C15 facilitates early viral spread by inhibiting NK cell contact

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Nov 2022
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Engineered human cytokine/antibody fusion proteins expand regulatory T cells and confer autoimmune disease protection

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Continuous sensing of IFNα by hepatic endothelial cells shapes a vascular antimetastatic barrier

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Tumor-associated macrophages expressing the transcription factor IRF8 promote T cell exhaustion in cancer

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Sep 2022
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Epigenetic remodeling by vitamin C potentiates plasma cell differentiation

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Aug 2022
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CD24-Siglec axis is an innate immune checkpoint against metaflammation and metabolic disorder

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Jun 2022
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Androgen receptor-mediated CD8+ T cell stemness programs drive sex differences in antitumor immunity

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Unravelling the sex-specific diversity and functions of adrenal gland macrophages

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Evaluating the glycolytic potential of mouse costimulated effector CD8+ T cells ex vivo

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Jan 2022
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Magnesium sensing via LFA-1 regulates CD8+ T cell effector function

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Nov 2021
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1-deoxysphingolipids bind to COUP-TF to modulate lymphatic and cardiac cell development

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Regulatory T cell differentiation is controlled by αKG-induced alterations in mitochondrial metabolism and lipid homeostasis

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Microbiota triggers STING-type I IFN-dependent monocyte reprogramming of the tumor microenvironment

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Isolation of mouse Kupffer cells for phenotypic and functional studies

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Identification of a Kupffer cell subset capable of reverting the T cell dysfunction induced by hepatocellular priming

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Hemozoin-mediated inflammasome activation limits long-lived anti-malarial immunity

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Immune mechanisms orchestrate tertiary lymphoid structures in tumors via cancer-associated fibroblasts

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Untitled document

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Untitled document

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Endogenous retroviruses promote homeostatic and inflammatory responses to the microbiota

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The loss of RNA N6-adenosine methyltransferase Mettl14 in tumor-associated macrophages promotes CD8+ T cell dysfunction and tumor growth

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Resident memory T cells in tumor-distant tissues fortify against metastasis formation

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Two sequential activation modules control the differentiation of protective T helper-1 (Th1) cells

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Functional Genomics In Vivo Reveal Metabolic Dependencies of Pancreatic Cancer Cells

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Positive selection of IgG+ over IgM+ B cells in the germinal center reaction

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SARS-CoV-2 mRNA Vaccines Foster Potent Antigen-Specific Germinal Center Responses Associated with Neutralizing Antibody Generation

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In Situ Maturation and Tissue Adaptation of Type 2 Innate Lymphoid Cell Progenitors

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Characterization of Resident Corneal Plasmacytoid Dendritic Cells and Their Pivotal Role in Herpes Simplex Keratitis

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Signaling through the Inhibitory Fc Receptor FcγRIIB Induces CD8+ T Cell Apoptosis to Limit T Cell Immunity

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Chronic Viral Infection Promotes Efficient Germinal Center B Cell Responses

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Interleukin-27 Is Essential for Type 1 Diabetes Development and Sjögren Syndrome-like Inflammation

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B Cells and T Follicular Helper Cells Mediate Response to Checkpoint Inhibitors in High Mutation Burden Mouse Models of Breast Cancer

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miR-15/16 Restrain Memory T Cell Differentiation, Cell Cycle, and Survival

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The Immunological Organ Environment Dictates the Molecular and Cellular Pathways of Cytotoxic Antibody Activity

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Gata6+ Pericardial Cavity Macrophages Relocate to the Injured Heart and Prevent Cardiac Fibrosis

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Polychromic Reporter Mice Reveal Unappreciated Innate Lymphoid Cell Progenitor Heterogeneity and Elusive ILC3 Progenitors in Bone Marrow

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Negative Co-stimulation Constrains T Cell Differentiation by Imposing Boundaries on Possible Cell States

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Re-evaluation of neuronal P2X7 expression using novel mouse models and a P2X7-specific nanobody

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