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Aug 2025
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Inhibiting KRAS with CD47 and immune checkpoint overcomes intrinsic resistance to combined KRAS and immune checkpoint inhibitor therapy

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1. scibot 30 Aug 2025
  
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  DOI: 10.1016/j.xcrm.2025.102317
  
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sciencedirect.com/science/article/pii/S2666379125003908
Jun 2025
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Epigenetic regulation of intracellular branched-chain amino acid homeostasis maintains a normal lifespan

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1. scibot 28 Jun 2025
  
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  DOI: 10.1016/j.isci.2025.112846
  
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sciencedirect.com/science/article/pii/S2589004225011071
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

PDZ-directed substrate recruitment is the primary determinant of specific 4E-BP1 dephosphorylation by PP1-Neurabin

2
1. scibot 25 Jun 2025
  
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  RRID:AB_331679
  
  DOI: 10.7554/eLife.103403
  
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2. scibot 25 Jun 2025
  
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  RRID:AB_331680
  
  DOI: 10.7554/eLife.103403
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12185105/
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A first-in-class EGFR-directed KRAS G12V selective inhibitor

1
1. scibot 21 Jun 2025
  
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  RRID:AB_331679
  
  DOI: 10.1016/j.ccell.2025.05.016
  
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sciencedirect.com/science/article/pii/S1535610825002259
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Delayed forebrain excitatory and inhibitory neurogenesis in STRADA-related megalencephaly via mTOR hyperactivity

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1. scibot 15 Jun 2025
  
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  RRID:AB_331679
  
  DOI: 10.1101/2025.05.13.653911
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12132401/
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PDF-html.html

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1. scibot 12 Jun 2025
  
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  RRID:AB_331679
  
  DOI: 10.1158/0008-5472.can-24-3785
  
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52.53.155.43/6d05284590fa38103d7fbc1633c815ab1c347fcd/PDF-html.html
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Insulin- and exercise-induced phosphoproteomics of human skeletal muscle identify REPS1 as a regulator of muscle glucose uptake

1
1. scibot 12 Jun 2025
  
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  RRID:AB_331679
  
  DOI: 10.1016/j.xcrm.2025.102163
  
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cell.com/cell-reports-medicine/fulltext/S2666-3791(25)00236-8
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Redundancy of the OST catalytic subunit facilitates therapeutic targeting of N-glycosylation

1
1. scibot 11 Jun 2025
  
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  RRID:AB_331679
  
  DOI: 10.1016/j.chembiol.2025.05.005
  
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sciencedirect.com/science/article/pii/S2451945625001667
Mar 2025
52.53.155.43 52.53.155.43

1-s2.0-S2589004225005565-main-html.html

1
1. scibot 28 Mar 2025
  
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  AB_331679
  
  DOI: 10.1016/j.isci.2025.112295
  
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52.53.155.43/60bd8b63b5057b3a2fd52107fc36eb4f600f9b31/1-s2.0-S2589004225005565-main-html.html
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A phase II trial of mTORC1/2 inhibition in STK11 deficient non small cell lung cancer

1
1. scibot 13 Mar 2025
  
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  RRID:AB_331679
  
  DOI: 10.1038/s41698-025-00838-4
  
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link.springer.com/article/10.1038/s41698-025-00838-4
Feb 2025
physoc.onlinelibrary.wiley.com physoc.onlinelibrary.wiley.com

Dietary nitrate supplementation mitigates age-related changes at the neuromuscular junction in mice

1
1. scibot 27 Feb 2025
  
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  DOI: 10.1113/JP287592
  
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physoc.onlinelibrary.wiley.com/doi/10.1113/JP287592
Jan 2025
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Ergothioneine improves healthspan of aged animals by enhancing cGPDH activity through CSE-dependent persulfidation

1
1. scibot 24 Jan 2025
  
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  RRID:AB_331679
  
  DOI: 10.1016/j.cmet.2024.12.008
  
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cell.com/cell-metabolism/fulltext/S1550-4131(24)00490-X
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Glioma-induced alterations in excitatory neurons are reversed by mTOR inhibition

1
1. scibot 23 Jan 2025
  
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  RRID:AB_331680
  
  DOI: 10.1016/j.neuron.2024.12.026
  
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sciencedirect.com/science/article/pii/S0896627324009267
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Mitochondrial uncouplers inhibit oncogenic E2F1 activity and prostate cancer growth

1
1. scibot 14 Jan 2025
  
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  RRID:AB_331679
  
  DOI: 10.1016/j.xcrm.2024.101890
  
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sciencedirect.com/science/article/pii/S266637912400661X
Dec 2024
52.53.155.43 52.53.155.43

Functional specialization of MITF, TFEB and TFE3 drives radically distinct adaptive gene expression programs in melanoma

1
1. scibot 27 Dec 2024
  
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  RRID:AB_331679
  
  DOI: 10.1101/2024.12.23.629393
  
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52.53.155.43/e70ff79afc559a11e17818daacbae0950eb62f01/PDF-html.html
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Reciprocal regulation of mTORC1 signaling and ribosomal biosynthesis determines cell cycle progression in activated T cells

1
1. scibot 20 Dec 2024
  
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  AB_331679
  
  DOI: 10.1126/scisignal.adi8753
  
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science.org/doi/10.1126/scisignal.adi8753
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A commonly inherited human PCSK9 germline variant drives breast cancer metastasis via LRP1 receptor

1
1. scibot 10 Dec 2024
  
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  RRID:AB_331679
  
  DOI: 10.1016/j.cell.2024.11.009
  
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sciencedirect.com/science/article/pii/S0092867424013266
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Phase separation of chimeric antigen receptor promotes immunological synapse maturation and persistent cytotoxicity

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1. scibot 02 Dec 2024
  
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  RRID:AB_331679
  
  DOI: 10.1016/j.immuni.2024.11.005
  
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sciencedirect.com/science/article/pii/S107476132400520X
Oct 2024
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Development of an orally bioavailable CDK12/13 degrader and induction of synthetic lethality with AKT pathway inhibition

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1. scibot 02 Oct 2024
  
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  AB_331679
  
  DOI: 10.1016/j.xcrm.2024.101752
  
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sciencedirect.com/science/article/pii/S2666379124004828
Sep 2024
onlinelibrary.wiley.com onlinelibrary.wiley.com

Neuronal and glial cell alterations involved in the retinal degeneration of the familial dysautonomia optic neuropathy

1
1. scibot 27 Sep 2024
  
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  AB_331679
  
  DOI: 10.1002/glia.24612
  
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onlinelibrary.wiley.com/doi/10.1002/glia.24612
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Identification of resistance mechanisms to small-molecule inhibition of TEAD-regulated transcription

1
1. scibot 26 Sep 2024
  
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  RRID:AB_331679
  
  DOI: 10.1038/s44319-024-00217-3
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11387499/
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Anabolic deficits and divergent unfolded protein response underlie skeletal and cardiac muscle growth impairments in the Yoshida hepatoma tumor model of cancer cachexia

1
1. scibot 25 Sep 2024
  
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  RRID:AB_331679
  
  DOI: 10.14814/phy2.70044
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11410559/
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GCN2 is a determinant of the response to WEE1 kinase inhibition in small-cell lung cancer

1
1. scibot 25 Sep 2024
  
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  RRID:AB_331679
  
  DOI: 10.1016/j.celrep.2024.114606
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11407228/
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“β-Hydroxybutyrate Recapitulates the Beneficial Effects of Ketogenic Metabolic Therapy in Polycystic Kidney Disease”

1
1. scibot 25 Sep 2024
  
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  AB_331679
  
  DOI: 10.1016/j.isci.2024.110773
  
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sciencedirect.com/science/article/pii/S2589004224019989
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Mapping of the contraction-induced phosphoproteome identifies TRIM28 as a significant regulator of skeletal muscle size and function

1
1. scibot 25 Sep 2024
  
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  RRID:AB_916156
  
  DOI: 10.1016/j.celrep.2021.108796
  
  Resource: (Cell Signaling Technology Cat# 4858, RRID:AB_916156)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:AB_916156
  
  Curator comments: Phospho-S6 Ribosomal Protein (Ser235/236) Antibody Cell Signaling Technology Cat# 2211
  
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sciencedirect.com/science/article/pii/S2211124721001108
Aug 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Nephron specific ATP6AP2 knockout increases urinary excretion of fatty acids and decreases renal cortical megalin expression

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1. scibot 22 Aug 2024
  
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  RRID:AB_331679
  
  DOI: 10.1038/s41598-024-69749-x
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11319469/
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Defining the KRAS- and ERK-dependent transcriptome in KRAS-mutant cancers

1
1. scibot 21 Aug 2024
  
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  RRID:AB_331679
  
  DOI: 10.1126/science.adk0775
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11301402/
Jul 2024
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A Kinome-Wide Synthetic Lethal CRISPR/Cas9 Screen Reveals That mTOR Inhibition Prevents Adaptive Resistance to CDK4/CDK6 Blockade in HNSCC

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1. scibot 31 Jul 2024
  
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  RRID:AB_331679
  
  DOI: 10.1158/2767-9764.CRC-24-0247
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11284272/
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Defining the KRAS- and ERK-dependent transcriptome in KRAS-mutant cancers

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1. scibot 18 Jul 2024
  
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  RRID:AB_331679
  
  DOI: 10.1126/science.adk0775
  
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science.org/doi/10.1126/science.adk0775
Jun 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Hippo-PKCζ-NFκB signaling axis: A druggable modulator of chondrocyte responses to mechanical stress

1
1. scibot 03 Jun 2024
  
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  RRID:AB_331679
  
  DOI: 10.1016/j.isci.2024.109983
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11140209/
May 2024
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Metabolic regulator LKB1 controls adipose tissue ILC2 PD-1 expression and mitochondrial homeostasis to prevent insulin resistance

1
1. scibot 21 May 2024
  
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  RRID:AB_331679
  
  DOI: 10.1016/j.immuni.2024.04.024
  
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sciencedirect.com/science/article/pii/S1074761324002292
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Glutamine promotes human CD8+ T cells and counteracts imiquimod-induced T cell hypo-responsiveness

1
1. scibot 15 May 2024
  
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  RRID:AB_331679
  
  DOI: 10.1016/j.isci.2024.109767
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11088342/
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Inhibition of protein translational machinery in triple-negative breast cancer as a promising therapeutic strategy

1
1. scibot 10 May 2024
  
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  RRID:AB_331679
  
  DOI: 10.1016/j.xcrm.2024.101552
  
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sciencedirect.com/science/article/pii/S2666379124002441
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Loss of tumor suppressor TMEM127 drives RET-mediated transformation through disrupted membrane dynamics

1
1. scibot 03 May 2024
  
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  RRID:AB_331679
  
  DOI: 10.7554/eLife.89100
  
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  Curator: @evieth
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11060712/
Apr 2024
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Single-cell systems pharmacology identifies development-driven drug response and combination therapy in B cell acute lymphoblastic leukemia

2
1. scibot 09 Apr 2024
  
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  DOI: 10.1016/j.ccell.2024.03.003
  
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NIBR-LTSi is a selective LATS kinase inhibitor activating YAP signaling and expanding tissue stem cells in vitro and in vivo

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Sexual Dimorphism of Circadian Liver Transcriptome.

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Trans-omic analysis reveals opposite metabolic dysregulation between feeding and fasting in liver associated with obesity

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Whitening of brown adipose tissue inhibits osteogenic differentiation via secretion of S100A8/A9

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Targeting DNA Repair and Survival Signaling in Diffuse Intrinsic Pontine Gliomas to Prevent Tumor Recurrence

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PI3K signaling promotes formation of lipid-laden foamy macrophages at the spinal cord injury site

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Metastatic or xenograft colorectal cancer induce divergent anabolic deficits and pro-inflammatory effectors of muscle wasting in a tumor-type dependent manner

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LP07 and LLC pre-clinical models of lung cancer induce divergent anabolic deficits and expression of pro-inflammatory effectors of muscle wasting

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Active growth signaling promotes senescence and cancer cell sensitivity to CDK7 inhibition

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Insulin receptor loss impairs mammary tumorigenesis in mice

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The HACE1 E3 ligase mediates RAC1-dependent control of mTOR signaling complexes

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TIM-3 blockade in diffuse intrinsic pontine glioma models promotes tumor regression and antitumor immune memory

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Ethanol changes Nestin-promoter induced neural stem cells to disturb newborn dendritic spine remodeling in the hippocampus of mice

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Screening in serum-derived medium reveals differential response to compounds targeting metabolism

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Short-term PI3K inhibition prevents breast cancer in preclinical models

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mTOR inhibition reprograms cellular proteostasis by regulating eIF3D-mediated selective mRNA translation and promotes cell phenotype switching

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Nucleoporin Seh1 maintains Schwann cell homeostasis by regulating genome stability and necroptosis

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IGF1R inhibition enhances the therapeutic effects of Gq/11 inhibition in metastatic uveal melanoma progression

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Single-cell transcriptomics of NRAS-mutated melanoma transitioning to drug resistance reveals P2RX7 as an indicator of early drug response

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Comparative landscape of genetic dependencies in human and chimpanzee stem cells

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Arginine depletion attenuates renal cystogenesis in tuberous sclerosis complex model

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Genetic deletion of skeletal muscle iPLA2γ results in mitochondrial dysfunction, muscle atrophy and alterations in whole-body energy metabolism

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Canagliflozin impairs T cell effector function via metabolic suppression in autoimmunity

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FOXK1 promotes nonalcoholic fatty liver disease by mediating mTORC1-dependent inhibition of hepatic fatty acid oxidation

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LKB1 controls inflammatory potential through CRTC2-dependent histone acetylation

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Stress-induced perturbations in intracellular amino acids reprogram mRNA translation in osmoadaptation independently of the ISR

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Synaptic hyperexcitability of cytomegalic pyramidal neurons contributes to epileptogenesis in tuberous sclerosis complex

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Emx1-Cre-mediated inactivation of PDK1 prevents plaque deposition in an Alzheimer’s disease-like mouse model

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NAD depletion mediates cytotoxicity in human neurons with autophagy deficiency

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Nutrient-sensing AgRP neurons relay control of liver autophagy during energy deprivation

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N-acetylcysteine overcomes NF1 loss-driven resistance to PI3Kα inhibition in breast cancer

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Large neutral amino acid levels tune perinatal neuronal excitability and survival

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A transcriptionally distinct subset of influenza-specific effector memory B cells predicts long-lived antibody responses to vaccination in humans

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Translational patterns of ionotropic glutamate and GABA receptors during brain development and behavioral stimuli revealed by polysome profiling

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Distinct but interchangeable subpopulations of colorectal cancer cells with different growth fates and drug sensitivity

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Jan 2023
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The TAZ-CAMTA1 Fusion Protein Promotes Tumorigenesis via Connective Tissue Growth Factor and Ras–MAPK Signaling in Epithelioid Hemangioendothelioma

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A central role for regulated protein stability in the control of TFE3 and MITF by nutrients

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AKTIP loss is enriched in ERα-positive breast cancer for tumorigenesis and confers endocrine resistance

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Reciprocal effects of mTOR inhibitors on pro-survival proteins dictate therapeutic responses in tuberous sclerosis complex

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Hypothalamic orexin prevents non-alcoholic steatohepatitis and hepatocellular carcinoma in obesity

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Shared and unique phosphoproteomics responses in skeletal muscle from exercise models and in hyperammonemic myotubes

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CROCCP2 acts as a human-specific modifier of cilia dynamics and mTOR signaling to promote expansion of cortical progenitors

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Selective advantage of epigenetically disrupted cancer cells via phenotypic inertia

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Phosphoproteomic mapping reveals distinct signaling actions and activation of muscle protein synthesis by Isthmin-1

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D2R signaling in striatal spiny neurons modulates L-DOPA induced dyskinesia

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Gut Parabacteroides merdae protects against cardiovascular damage by enhancing branched-chain amino acid catabolism

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Hyperactivation of mTORC1 in a double hit mutant zebrafish model of tuberous sclerosis complex causes increased seizure susceptibility and neurodevelopmental abnormalities

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Destabilization of TP53 by USP10 is essential for neonatal autophagy and survival

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Targeting the USP7/RRM2 axis drives senescence and sensitizes melanoma cells to HDAC/LSD1 inhibitors

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OMA1-mediated integrated stress response protects against ferroptosis in mitochondrial cardiomyopathy

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Condensed-phase signaling can expand kinase specificity and respond to macromolecular crowding

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Hyperactivation of mTOR and AKT in a cardiac hypertrophy animal model of Friedreich ataxia

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Glutamine metabolism modulates chondrocyte inflammatory response

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Genetic Inhibition of PDK1 Robustly Reduces Plaque Deposition and Ameliorates Gliosis in the 5×FAD Mouse Model of Alzheimer’s Disease

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GCN2 inhibition sensitizes arginine-deprived hepatocellular carcinoma cells to senolytic treatment

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Stromal AR inhibits prostate tumor progression by restraining secretory luminal epithelial cells

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The oncoprotein BCL6 enables solid tumor cells to evade genotoxic stress

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Patient-derived models of brain metastases recapitulate human disseminated disease

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Tissue remodeling by an opportunistic pathogen triggers allergic inflammation

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The oncogene-dependent resistance to reprogramming unveils cancer therapeutic targets

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Structure-based design of CDC42 effector interaction inhibitors for the treatment of cancer

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Regulation of GTPase function by autophosphorylation

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A combined cell and gene therapy approach for homotopic reconstruction of midbrain dopamine pathways using human pluripotent stem cells

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Mitochondrial complex I inhibitors suppress tumor growth through concomitant acidification of the intra- and extracellular environment

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mTOR-dependent translation drives tumor infiltrating CD8+ effector and CD4+ Treg cells expansion

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Genomic alterations in PIK3CA-mutated breast cancer result in mTORC1 activation and limit the sensitivity to PI3Kα inhibitors

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Protocol for the assessment of mTOR activity in mouse primary hepatocytes

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Plasmacytoid dendritic cell activation is dependent on coordinated expression of distinct amino acid transporters

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Uteroplacental nutrient flux and evidence for metabolic reprogramming during sustained hypoxemia

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Oncogene-dependent sloppiness in mRNA translation

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A feedback loop between the androgen receptor and 6-phosphogluoconate dehydrogenase (6PGD) drives prostate cancer growth

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NANOS2 suppresses the cell cycle by repressing mTORC1 activators in embryonic male germ cells

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Multisite Phosphorylation of S6K1 Directs a Kinase Phospho-code that Determines Substrate Selection

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Isthmin-1 is an adipokine that promotes glucose uptake and improves glucose tolerance and hepatic steatosis

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Raptor directs Sertoli cell cytoskeletal organization and polarity in the mouse testis

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Minute amounts of hamartin wildtype rescue the emergence of tuber-like lesions in conditional Tsc1 ablated mice - ScienceDirect

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Splicing factor SRSF1 is indispensable for regulatory T cell homeostasis and function

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Co-occurring gain-of-function mutations in HER2 and HER3 modulate HER2/HER3 activation, oncogenesis, and HER2 inhibitor sensitivity

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Mismatch repair deficiency predicts response to HER2 blockade in HER2-negative breast cancer

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Contrasting recruitment of skin-associated adipose depots during cold challenge of mouse and human

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Chromatin accessibility governs the differential response of cancer and T cells to arginine starvation

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mTOR signaling regulates gastric epithelial progenitor homeostasis and gastric tumorigenesis via MEK1-ERKs and BMP-Smad1 pathways

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A Cell-Autonomous Signature of Dysregulated Protein Phosphorylation Underlies Muscle Insulin Resistance in Type 2 Diabetes

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SGLT2 Inhibition Mediates Protection from Diabetic Kidney Disease by Promoting Ketone Body-Induced mTORC1 Inhibition

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Origins and Proliferative States of Human Oligodendrocyte Precursor Cells

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Single-cell atlas of early human brain development highlights heterogeneity of human neuroepithelial cells and early radial glia

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Metabolic modulation by CDK4/6 inhibitor promotes chemokine-mediated recruitment of T cells into mammary tumors

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Metabolic conditioning of CD8 + effector T cells for adoptive cell therapy

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  anti-phospho-S6Ser235/236
  
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ErbB3 is a critical regulator of cytoskeletal dynamics in brain microvascular endothelial cells: Implications for vascular remodeling and blood-brain-barrier modulation - Limin Wu, Mohammad R Islam, Janice Lee, Hajime Takase, Shuzhen Guo, Allison M Andrews, Tetyana P Buzhdygan, Justin Mathew, Wenlu Li, Ken Arai, Eng H Lo, Servio H Ramirez, Josephine Lok, 2021

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Whole brain delivery of an instability-prone Mecp2 transgene improves behavioral and molecular pathological defects in mouse models of Rett syndrome

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Comprehensive pharmacogenomic characterization of gastric cancer

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Reduced Na+K+‐ATPase activity may reduce amino acid uptake in IUGR fetal sheep muscle despite unchanged ex vivo amino acid transporter activity

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Synergistic growth inhibition mediated by dual PI3K/mTOR pathway targeting and genetic or direct pharmacological AKT inhibition in human glioblastoma models

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Single-cell resolved imaging reveals intra-tumor heterogeneity in glycolysis, transitions between metabolic states, and their regulatory mechanisms

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cell.com/cell-reports/fulltext/S2211-1247(21)00063-2
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G3BPs tether the TSC complex to lysosomes and suppress mTORC1 signaling

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Actionable Cytopathogenic Host Responses of Human Alveolar Type 2 Cells to SARS-CoV-2

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Divergent Roles of PI3K Isoforms in PTEN-Deficient Glioblastomas

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Peculiar protrusions along tanycyte processes face diverse neural and non‐neural cell types in the hypothalamic parenchyma

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Metabolic Imaging Detects Resistance to PI3Kα Inhibition Mediated by Persistent FOXM1 Expression in ER+ Breast Cancer

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Inhibition of striatonigral autophagy as a link between cannabinoid intoxication and impairment of motor coordination

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mTORC1 Signaling Controls TLR2-Mediated T-Cell Activation by Inducing TIRAP Expression

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Regulation of Hippocampal Memory by mTORC1 in Somatostatin Interneurons

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Metabolic Fingerprinting Links Oncogenic PIK3CA with Enhanced Arachidonic Acid-Derived Eicosanoids

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Dopaminergic Control of Striatal Cholinergic Interneurons Underlies Cocaine-Induced Psychostimulation

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Late Endosomes Act as mRNA Translation Platforms and Sustain Mitochondria in Axons

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Viral Delivery of GDNF Promotes Functional Integration of Human Stem Cell Grafts in Parkinson’s Disease

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Regulation of stem cell function and neuronal differentiation by HERV-K via mTOR pathway

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mTOR signaling regulates the morphology and migration of outer radial glia in developing human cortex

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Hyperactivation of TORC1 Drives Resistance to the Pan-HER Tyrosine Kinase Inhibitor Neratinib in HER2-Mutant Cancers

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β2‐adrenoceptor activation improves skeletal muscle autophagy in neurogenic myopathy

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AMPK-Regulated Astrocytic Lactate Shuttle Plays a Non-Cell-Autonomous Role in Neuronal Survival

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Inhibition of Tumor VEGFR2 Induces Serine 897 EphA2-Dependent Tumor Cell Invasion and Metastasis in NSCLC

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Indirect monitoring of TORC1 signalling pathway reveals molecular diversity among different yeast strains

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Thrombospondin-1 Mediates Axon Regeneration in Retinal Ganglion Cells

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Truncated BRPF1 Cooperates with Smoothened to Promote Adult Shh Medulloblastoma

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KAE1 Allelic Variants Affect TORC1 Activation and Fermentation Kinetics in Saccharomyces cerevisiae

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Long-distance axon regeneration promotes recovery of diaphragmatic respiratory function after spinal cord injury

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Mechanisms of Convergent Egg Provisioning in Poison Frogs

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Effects of the presence and absence of amino acids on translation, signaling and long‐term depression in hippocampal slices from Fmr1 knockout mice

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Dysregulation of Mitochondrial Ca2+ Uptake and Sarcolemma Repair Underlie Muscle Weakness and Wasting in Patients and Mice Lacking MICU1

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KRAS Suppression-Induced Degradation of MYC Is Antagonized by a MEK5-ERK5 Compensatory Mechanism

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Nucleoporin Seh1 Interacts with Olig2/Brd7 to Promote Oligodendrocyte Differentiation and Myelination

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PAX3 Confers Functional Heterogeneity in Skeletal Muscle Stem Cell Responses to Environmental Stress

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Genetic Analysis Reveals AMPK Is Required to Support Tumor Growth in Murine Kras-Dependent Lung Cancer Models

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  DOI: 10.1016/j.cell.2018.11.030
  
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sciencedirect.com/science/article/pii/S0092867418315551
Nov 2018
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Sensitive Periods for Cerebellar-Mediated Autistic-like Behaviors

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The Translational Machinery of Human CD4+ T Cells Is Poised for Activation and Controls the Switch from Quiescence to Metabolic Remodeling

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Autocrine Mfge8 Signaling Prevents Developmental Exhaustion of the Adult Neural Stem Cell Pool

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Identification of Therapeutic Targets in Rhabdomyosarcoma through Integrated Genomic, Epigenomic, and Proteomic Analyses

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Raptor directs Sertoli cell cytoskeletal organization and polarity in the mouse testis

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Adaptive Fibrogenic Reprogramming of Osteosarcoma Stem Cells Promotes Metastatic Growth

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mTORC1-Mediated Inhibition of 4EBP1 Is Essential for Hedgehog Signaling-Driven Translation and Medulloblastoma

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Unbiased Combinatorial Screening Identifies a Bispecific IgG1 that Potently Inhibits HER3 Signaling via HER2-Guided Ligand Blockade

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Phosphatidylinositol-5-Phosphate 4-Kinases Regulate Cellular Lipid Metabolism By Facilitating Autophagy

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Interventions Targeting Glucocorticoid-Krüppel-like Factor 15-Branched-Chain Amino Acid Signaling Improve Disease Phenotypes in Spinal Muscular Atrophy Mice

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Untitled document

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ebiomedicine.com/article/S2352-3964(18)30152-X/abstract
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Systematic Functional Annotation of Somatic Mutations in Cancer

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Decreased rates of cerebral protein synthesis measured in vivo in a mouse model of Tuberous Sclerosis Complex: unexpected consequences of reduced tuberin

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Rescue of Learning and Memory Deficits in the Human Nonsyndromic Intellectual Disability Cereblon Knock-Out Mouse Model by Targeting the AMP-Activated Protein Kinase–mTORC1 Translational Pathway

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Cooperative Epigenetic Remodeling by TET2 Loss and NRAS Mutation Drives Myeloid Transformation and MEK Inhibitor Sensitivity

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Post-transcriptional Regulation of De Novo Lipogenesis by mTORC1-S6K1-SRPK2 Signaling

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Nov 2017
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Context Specificity in Causal Signaling Networks Revealed by Phosphoprotein Profiling

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Spatial Activation of TORC1 Is Regulated by Hedgehog and E2F1 Signaling in the Drosophila Eye

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Subthalamic Nucleus Deep Brain Stimulation Employs trkB Signaling for Neuroprotection and Functional Restoration

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Diurnal Oscillations in Liver Mass and Cell Size Accompany Ribosome Assembly Cycles

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Focal Adhesion- and IGF1R-Dependent Survival and Migratory Pathways Mediate Tumor Resistance to mTORC1/2 Inhibition

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Pimozide reduces toxic forms of tau in TauC3 mice via AMPK‐mediated autophagy

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