139 Matching Annotations
  1. Last 7 days
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    FANCM promotes PARP inhibitor resistance by minimizing ssDNA gap formation and counteracting resection inhibition
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    sciencedirect.com/science/article/pii/S2211124724007939
  3. Jul 2024
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    CYRI-B-mediated macropinocytosis drives metastasis via lysophosphatidic acid receptor uptake
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    ncbi.nlm.nih.gov/pmc/articles/PMC11219039/
  5. May 2024
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    Subthalamic nucleus but not entopeduncular nucleus deep brain stimulation enhances neurogenesis in the SVZ-olfactory bulb system of Parkinsonian rats
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  7. 52.53.155.43 52.53.155.43
    Unprocessed Genomic Uracil as a Source of DNA Replication Stress in Cancer Cells
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  8. Apr 2024
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    Unprocessed genomic uracil as a source of DNA replication stress in cancer cells
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    sciencedirect.com/science/article/pii/S109727652400282X
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    BRCA1 and 53BP1 regulate reprogramming efficiency by mediating DNA repair pathway choice at replication-associated double-strand breaks
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    sciencedirect.com/science/article/pii/S2211124724003346
  11. Mar 2024
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    RTF2 controls replication repriming and ribonucleotide excision at the replisome
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    ncbi.nlm.nih.gov/pmc/articles/PMC10908796/
  13. Feb 2024
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    A Phase 1 Expansion Cohort Study Evaluating the Safety and Efficacy of the CHK1 Inhibitor LY2880070 with Low-Dose Gemcitabine in Metastatic Pancreatic Adenocarcinoma Patients
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    Poly(ADP-ribosyl)ation of TIMELESS limits DNA replication stress and promotes stalled fork protection
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    DNA combing versus DNA spreading and the separation of sister chromatids
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    ncbi.nlm.nih.gov/pmc/articles/PMC10840220/
  17. Jan 2024
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    In silico protein interaction screening uncovers DONSON’s role in replication initiation
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    BRCA2 promotes genomic integrity and therapy resistance primarily through its role in homology-directed repair
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  20. Dec 2023
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    Metabolic regulation of homologous recombination repair by MRE11 lactylation
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    Ethanol induces replication fork stalling and membrane stress in immortalized laryngeal cells
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    Shh from mossy cells contributes to preventing NSC pool depletion after seizure-induced neurogenesis and in aging
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  24. 52.53.155.43 52.53.155.43
    ccr-23-2005-html.html
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  25. Nov 2023
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    Aging Modulates the Ability of Quiescent Radial Glia-Like Stem Cells in the Hippocampal Dentate Gyrus to be Recruited into Division by Pro-neurogenic Stimuli
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  27. Oct 2023
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    The splicing factor DHX38 enables retinal development through safeguarding genome integrity
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    PCDH12 loss results in premature neuronal differentiation and impeded migration in a cortical organoid model
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  30. Aug 2023
  31. www.science.org www.science.org
    In silico protein interaction screening uncovers DONSON’s role in replication initiation
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    Shh from mossy cells contributes to preventing NSC pool depletion after seizure-induced neurogenesis and in aging
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    Structural insight into H4K20 methylation on H2A.Z-nucleosome by SUV420H1
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    sciencedirect.com/science/article/abs/pii/S1097276523005154
  34. Jun 2023
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    Oncogenic IDH mutations increase heterochromatin-related replication stress without impacting homologous recombination
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  36. May 2023
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    Deficiency in mammalian STN1 promotes colon cancer development via inhibiting DNA repair
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    Deficiency in mammalian STN1 promotes colon cancer development via inhibiting DNA repair
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    DNA Combing versus DNA Spreading and the Separation of Sister Chromatids
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    Replication stress impairs chromosome segregation and preimplantation development in human embryos
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  41. Apr 2023
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    Polymerase iota (Pol ι) prevents PrimPol-mediated nascent DNA synthesis and chromosome instability
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    Polymerase iota (Pol ι) prevents PrimPol-mediated nascent DNA synthesis and chromosome instability
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  44. Jan 2023
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    Cytosolic DNA sensing by cGAS/STING promotes TRPV2-mediated Ca2+ release to protect stressed replication forks
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    sciencedirect.com/science/article/pii/S1097276522012175
  46. Dec 2022
  47. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    NEDDylated Cullin 3 mediates the adaptive response to topoisomerase 1 inhibitors
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    NEDDylated Cullin 3 mediates the adaptive response to topoisomerase 1 inhibitors
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  49. Nov 2022
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    POLθ prevents MRE11-NBS1-CtIP-dependent fork breakage in the absence of BRCA2/RAD51 by filling lagging-strand gaps
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    Long non-coding RNA PCAT19 safeguards DNA in quiescent endothelial cells by preventing uncontrolled phosphorylation of RPA2
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    sciencedirect.com/science/article/pii/S2211124722015443
  52. academic.oup.com academic.oup.com
    Multiple-low-dose therapy: effective killing of high-grade serous ovarian cancer cells with ATR and CHK1 inhibitors
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      DOI: 10.1093/narcan/zcac036

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    academic.oup.com/narcancer/article/4/4/zcac036/6825304
  53. Jul 2022
  54. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Malignant pleural mesothelioma nodules remodel their surroundings to vascularize and grow
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    ncbi.nlm.nih.gov/pmc/articles/PMC9271443/
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    Tbr1 Misexpression Alters Neuronal Development in the Cerebral Cortex
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      DOI: 10.1007/s12035-022-02936-x

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    link.springer.com/article/10.1007/s12035-022-02936-x
  56. May 2022
  57. www.sciencedirect.com www.sciencedirect.com
    A PARylation-phosphorylation cascade promotes TOPBP1 loading and RPA-RAD51 exchange in homologous recombination
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  58. Mar 2022
  59. faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com
    PTENα regulates endocytosis and modulates olfactory function
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  64. Dec 2021
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    The protease SPRTN and SUMOylation coordinate DNA-protein crosslink repair to prevent genome instability
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    DDK/Hsk1 phosphorylates and targets fission yeast histone deacetylase Hst4 for degradation to stabilize stalled DNA replication forks
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  70. Oct 2021
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    Replication catastrophe is responsible for intrinsic PAR glycohydrolase inhibitor-sensitivity in patient-derived ovarian cancer models
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    Temporally distinct post-replicative repair mechanisms fill PRIMPOL-dependent ssDNA gaps in human cells
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    Loss of nuclear DNA ligase III reverts PARP inhibitor resistance in BRCA1/53BP1 double-deficient cells by exposing ssDNA gaps
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    REV1-Polζ maintains the viability of homologous recombination-deficient cancer cells through mutagenic repair of PRIMPOL-dependent ssDNA gaps
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  77. Aug 2021
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    PTENα regulates endocytosis and modulates olfactory function
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  82. Jul 2021
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    Suppressor of fused controls perinatal expansion and quiescence of future dentate adult neural stem cells
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    Microglial Phagocytosis of Newborn Cells Is Induced by Endocannabinoids and Sculpts Sex Differences in Juvenile Rat Social Play
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    ATR Signaling Uncouples the Role of RAD51 Paralogs in Homologous Recombination and Replication Stress Response
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    Replication gaps are a key determinant of PARP inhibitor synthetic lethality with BRCA deficiency
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  92. Jun 2021
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  94. May 2021
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    Targeting KDM4A epigenetically activates tumor-cell-intrinsic immunity by inducing DNA replication stress
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    The ZATT-TOP2A-PICH Axis Drives Extensive Replication Fork Reversal to Promote Genome Stability
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    PCAF-Mediated Histone Acetylation Promotes Replication Fork Degradation by MRE11 and EXO1 in BRCA-Deficient Cells
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    HLTF Promotes Fork Reversal, Limiting Replication Stress Resistance and Preventing Multiple Mechanisms of Unrestrained DNA Synthesis
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  100. Feb 2021
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    Role of GnRH isoforms in paracrine/autocrine control of zebrafish ( Danio rerio ) spermatogenesis
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    DNA ADP-Ribosylation Stalls Replication and Is Reversed by RecF-Mediated Homologous Recombination and Nucleotide Excision Repair
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    Control of replication stress and mitosis in colorectal cancer stem cells through the interplay of PARP1, MRE11 and RAD51
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  106. Dec 2020
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    Inflammation of the Embryonic Choroid Plexus Barrier following Maternal Immune Activation
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    ROS Dynamics Delineate Functional States of Hippocampal Neural Stem Cells and Link to Their Activity-Dependent Exit from Quiescence
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    Human CST complex protects stalled replication forks by directly blocking MRE11 degradation of nascent‐strand DNA
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  110. Nov 2020
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    TRF2 Mediates Replication Initiation within Human Telomeres to Prevent Telomere Dysfunction
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  112. Oct 2020
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    MYC Promotes Bone Marrow Stem Cell Dysfunction in Fanconi Anemia
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    DNA Replication Vulnerabilities Render Ovarian Cancer Cells Sensitive to Poly(ADP-Ribose) Glycohydrolase Inhibitors
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    CtIP-Mediated Fork Protection Synergizes with BRCA1 to Suppress Genomic Instability upon DNA Replication Stress
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    The BRCT Domains of the BRCA1 and BARD1 Tumor Suppressors Differentially Regulate Homology-Directed Repair and Stalled Fork Protection
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    Dual Roles of Poly(dA:dT) Tracts in Replication Initiation and Fork Collapse
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    Selective Loss of PARG Restores PARylation and Counteracts PARP Inhibitor-Mediated Synthetic Lethality
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    Stochastic Endogenous Replication Stress Causes ATR-Triggered Fluctuations in CDK2 Activity that Dynamically Adjust Global DNA Synthesis Rates
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  157. www.sciencedirect.com www.sciencedirect.com
    Polε Instability Drives Replication Stress, Abnormal Development, and Tumorigenesis
    1
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      RRID:AB_400326

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  158. www.sciencedirect.com www.sciencedirect.com
    Genome-wide Control of Heterochromatin Replication by the Telomere Capping Protein TRF2
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  159. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Untitled document
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  160. www.sciencedirect.com www.sciencedirect.com
    Replication Fork Slowing and Reversal upon DNA Damage Require PCNA Polyubiquitination and ZRANB3 DNA Translocase Activity
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  161. Nov 2017
  162. www.sciencedirect.com www.sciencedirect.com
    Ribonucleotide Reductase Requires Subunit Switching in Hypoxia to Maintain DNA Replication
    1
    1. scibot 08 Nov 2017
      Mouse anti-BrdU Clone B44BD Transduction LaboratoriesCat# 347580

      Curator: @Jmenke

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  163. www.sciencedirect.com www.sciencedirect.com
    RADX Promotes Genome Stability and Modulates Chemosensitivity by Regulating RAD51 at Replication Forks
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  164. www.sciencedirect.com www.sciencedirect.com
    Mosaic Analysis with Double Markers Reveals Distinct Sequential Functions of Lgl1 in Neural Stem Cells
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  165. www.sciencedirect.com www.sciencedirect.com
    Serotonergic Projections Govern Postnatal Neuroblast Migration
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      AB_400326

      Curator: @kaitlinsung

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  166. www.sciencedirect.com www.sciencedirect.com
    Mex3a Marks a Slowly Dividing Subpopulation of Lgr5+ Intestinal Stem Cells
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      AB_400326

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  167. elifesciences.org elifesciences.org
    Supporting cells remove and replace sensory receptor hair cells in a balance organ of adult mice
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  168. www.jneurosci.org www.jneurosci.org
    In Utero Exposure to Valproic Acid Induces Neocortical Dysgenesis via Dysregulation of Neural Progenitor Cell Proliferation/Differentiation
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      AB_400326

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    jneurosci.org/content/36/42/10908.long
  169. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Two subunits of human ORC are dispensable for DNA replication and proliferation
    1
    1. scibot 08 Nov 2017
      AB_400326

      Curator: @gabimpine

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    ncbi.nlm.nih.gov/pmc/articles/PMC5245961/
  170. www.sciencedirect.com www.sciencedirect.com
    Bcl-xL dependency coincides with the onset of neurogenesis in the developing mammalian spinal cord
    1
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      AB_400326

      Curator: @chewbeccax

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    sciencedirect.com/science/article/pii/S1044743116301579
  171. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Spatial distribution and cellular composition of adult brain proliferative zones in the teleost, Gymnotus omarorum
    1
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      AB_400326

      Curator: @gabimpine

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    ncbi.nlm.nih.gov/pmc/articles/PMC4157608/
  172. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Wls Provides a New Compartmental View of the Rhombic Lip in Mouse Cerebellar Development
    1
    1. scibot 08 Nov 2017
      AB_400326

      Curator: @gabimpine

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