621 Matching Annotations
  1. Last 7 days
  2. www.sciencedirect.com www.sciencedirect.com
    The Cullin3-Rbx1-KLHL9 E3 ubiquitin ligase complex ubiquitinates Rheb and supports amino acid-induced mTORC1 activation
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    1. scibot 21 Dec 2024
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      DOI: 10.1016/j.celrep.2024.115101

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    sciencedirect.com/science/article/pii/S2211124724014529
  3. Dec 2024
  4. www.science.org www.science.org
    Reduced striatal M4-cholinergic signaling following dopamine loss contributes to parkinsonian and l-DOPA–induced dyskinetic behaviors
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    1. scibot 13 Dec 2024
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      DOI: 10.1126/sciadv.adp6301

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    science.org/doi/10.1126/sciadv.adp6301
  5. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Single-cell analysis reveals host S phase drives large T antigen expression during BK polyomavirus infection
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    1. scibot 11 Dec 2024
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      DOI: 10.1371/journal.ppat.1012663

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    pmc.ncbi.nlm.nih.gov/articles/PMC11620372/
  6. 52.53.155.43 52.53.155.43
    1-s2.0-S2589004224027433-main-html.html
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    1. scibot 06 Dec 2024
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    52.53.155.43/4cd936c6d252d720783f395bd288e7a8753b9204/1-s2.0-S2589004224027433-main-html.html
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    DNA hypomethylation promotes UHRF1-and SUV39H1/H2-dependent crosstalk between H3K18ub and H3K9me3 to reinforce heterochromatin states
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    1. scibot 05 Dec 2024
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      DOI: 10.1016/j.molcel.2024.11.009

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    sciencedirect.com/science/article/pii/S1097276524009146
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    Proteolethargy is a pathogenic mechanism in chronic disease
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    1. scibot 02 Dec 2024
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      DOI: 10.1016/j.cell.2024.10.051

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    sciencedirect.com/science/article/pii/S0092867424012741
  9. Nov 2024
  10. www.sciencedirect.com www.sciencedirect.com
    AMPK regulates Bcl2-L-13-mediated mitophagy induction for cardioprotection
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    1. scibot 28 Nov 2024
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      DOI: 10.1016/j.celrep.2024.115001

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    sciencedirect.com/science/article/pii/S2211124724013524
  11. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Calcium-dependent regulation of neuronal excitability is rescued in Fragile X Syndrome by a tat-conjugated N-terminal fragment of FMRP
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    1. scibot 26 Nov 2024
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      DOI: 10.1523/JNEUROSCI.0136-24.2024

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    pmc.ncbi.nlm.nih.gov/articles/PMC11112635/
  12. www.science.org www.science.org
    Reduced striatal M4-cholinergic signaling following dopamine loss contributes to parkinsonian and l-DOPA–induced dyskinetic behaviors
    1
    1. scibot 23 Nov 2024
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      DOI: 10.1126/sciadv.adp6301

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    science.org/doi/10.1126/sciadv.adp6301
  13. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    CEP192 localises mitotic Aurora-A activity by priming its interaction with TPX2
    1
    1. scibot 21 Nov 2024
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      DOI: 10.1038/s44318-024-00240-z

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    pmc.ncbi.nlm.nih.gov/articles/PMC11574021/
  14. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Identification of ERAD-dependent degrons for the endoplasmic reticulum lumen
    1
    1. scibot 14 Nov 2024
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      DOI: 10.7554/eLife.89606

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    pmc.ncbi.nlm.nih.gov/articles/PMC11556787/
  15. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Protocol for validating liquid-liquid phase separation as a driver of membraneless organelle assembly in vitro and in human cells
    1
    1. scibot 10 Nov 2024
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      DOI: 10.1016/j.xpro.2024.103410

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    pmc.ncbi.nlm.nih.gov/articles/PMC11541453/
  16. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    β2-integrins control HIF1α activation in human neutrophils
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    1. scibot 07 Nov 2024
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      DOI: 10.3389/fimmu.2024.1406967

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    pmc.ncbi.nlm.nih.gov/articles/PMC11513320/
  17. Oct 2024
  18. www.sciencedirect.com www.sciencedirect.com
    Voluntary exercise suppresses inflammation and improves insulin resistance in the arcuate nucleus and ventral tegmental area in mice on a high-fat diet
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    1. scibot 02 Oct 2024
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      DOI: 10.1016/j.physbeh.2024.114703

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    sciencedirect.com/science/article/pii/S0031938424002518
  19. Sep 2024
  20. www.sciencedirect.com www.sciencedirect.com
    C9orf72 poly-PR forms anisotropic condensates causative of nuclear TDP-43 pathology
    1
    1. scibot 26 Sep 2024
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      DOI: 10.1016/j.isci.2024.110937

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    sciencedirect.com/science/article/pii/S258900422402162X
  21. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Prominin 1 and Tweety Homology 1 both induce extracellular vesicle formation
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    1. scibot 25 Sep 2024
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      DOI: 10.7554/eLife.100061

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    ncbi.nlm.nih.gov/pmc/articles/PMC11405016/
  22. academic.oup.com academic.oup.com
    Ghrelin-Induced Sodium Reabsorption is Mediated by PKA and Microtubule-Dependent αE Na C Translocation In Female Rats
    2
    1. scibot 25 Sep 2024
      RRID:AB_772206

      DOI: 10.1210/js.2019-00121

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    2. scibot 25 Sep 2024
      RRID:AB_772210

      DOI: 10.1210/js.2019-00121

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    academic.oup.com/jes/article/3/11/2088/5556717
  23. www.sciencedirect.com www.sciencedirect.com
    Osmotic stress induces formation of both liquid condensates and amyloids by a yeast prion domain
    1
    1. scibot 17 Sep 2024
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      DOI: 10.1016/j.jbc.2024.107766

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    sciencedirect.com/science/article/pii/S0021925824022671
  24. aacrjournals.org aacrjournals.org
    Activating mTOR mutations are detrimental in nutrient-poor conditions
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    1. scibot 12 Sep 2024
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      DOI: 10.1158/0008-5472.CAN-22-0121

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    aacrjournals.org/cancerres/article/82/18/3263/709030/Activating-mTOR-Mutations-Are-Detrimental-in
  25. www.sciencedirect.com www.sciencedirect.com
    FYVE1/FREE1 is involved in glutamine-responsive TORC1 activation in plants
    1
    1. scibot 10 Sep 2024
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    sciencedirect.com/science/article/pii/S258900422402039X
  26. www.sciencedirect.com www.sciencedirect.com
    Multiple direct and indirect roles of the Paf1 complex in transcription elongation, splicing, and histone modifications
    1
    1. scibot 10 Sep 2024
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      DOI: 10.1016/j.celrep.2024.114730

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    sciencedirect.com/science/article/pii/S2211124724010817
  27. www.sciencedirect.com www.sciencedirect.com
    Disorder-mediated interactions target proteins to specific condensates
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    1. scibot 04 Sep 2024
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      DOI: 10.1016/j.molcel.2024.08.017

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    sciencedirect.com/science/article/pii/S1097276524006713
  28. Aug 2024
  29. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Knockout of the orphan membrane transporter Slc22a23 leads to a lean and hyperactive phenotype with a small hippocampal volume
    1
    1. scibot 30 Aug 2024
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      DOI: 10.1371/journal.pone.0309461

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    ncbi.nlm.nih.gov/pmc/articles/PMC11356391/
  30. www.sciencedirect.com www.sciencedirect.com
    MOF-mediated PRDX1 acetylation regulates inflammatory macrophage activation
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      DOI: 10.1016/j.celrep.2024.114682

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    sciencedirect.com/science/article/pii/S2211124724010337
  31. physoc.onlinelibrary.wiley.com physoc.onlinelibrary.wiley.com
    Metabolomics of repetitive myocardial stunning in chronic multivessel coronary artery stenosis: Effect of non-selective and selective β1-receptor blockers
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    1. scibot 29 Aug 2024
      RRID:AB_772

      DOI: 10.1113/JP285720

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    physoc.onlinelibrary.wiley.com/doi/10.1113/JP285720
  32. www.sciencedirect.com www.sciencedirect.com
    Disruption of nuclear speckle integrity dysregulates RNA splicing in C9ORF72-FTD/ALS
    1
    1. scibot 27 Aug 2024
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      DOI: 10.1016/j.neuron.2024.07.025

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    sciencedirect.com/science/article/pii/S0896627324005701
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    Engineering acyclovir-induced RNA nanodevices for reversible and tunable control of aptamer function
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      DOI: 10.1016/j.chembiol.2024.07.017

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    sciencedirect.com/science/article/pii/S2451945624003192
  34. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Association with TFIIIC limits MYCN localisation in hubs of active promoters and chromatin accumulation of non-phosphorylated RNA polymerase II
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    1. scibot 26 Aug 2024
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      DOI: 10.7554/eLife.94407

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    ncbi.nlm.nih.gov/pmc/articles/PMC11343564/
  35. www.sciencedirect.com www.sciencedirect.com
    Nucleosome remodeler exclusion by histone deacetylation enforces heterochromatic silencing and epigenetic inheritance
    1
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    sciencedirect.com/science/article/pii/S1097276524005823
  36. www.biorxiv.org www.biorxiv.org
    Beta-arrestin 1 mediated Src activation via Src SH3 domain revealed by cryo-electron microscopy
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    1. scibot 18 Aug 2024
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      DOI: 10.1101/2024.07.31.605623

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    biorxiv.org/content/10.1101/2024.07.31.605623v1
  37. www.frontiersin.org www.frontiersin.org
    Role of Posterodorsal Medial Amygdala Urocortin-3 in Pubertal Timing in Female Mice
    1
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      DOI: 10.3389/fendo.2022.893029

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    frontiersin.org/articles/10.3389/fendo.2022.893029
  38. Jul 2024
  39. www.sciencedirect.com www.sciencedirect.com
    ATAD1 prevents clogging of TOM and damage caused by un-imported mitochondrial proteins
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      DOI: 10.1016/j.celrep.2024.114473

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    sciencedirect.com/science/article/pii/S2211124724008027
  40. www.biorxiv.org www.biorxiv.org
    MDC1 mediates Pellino recruitment to sites of DNA double-strand breaks
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    1. scibot 26 Jul 2024
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      DOI: 10.1101/2024.07.20.604390

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    biorxiv.org/lookup/doi/10.1101/2024.07.20.604390
  41. www.sciencedirect.com www.sciencedirect.com
    Citrate metabolism controls the senescent microenvironment via the remodeling of pro-inflammatory enhancers
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      DOI: 10.1016/j.celrep.2024.114496

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    sciencedirect.com/science/article/pii/S2211124724008258
  42. www.cell.com www.cell.com
    Disruption of TGF-β signaling pathway is required to mediate effective killing of hepatocellular carcinoma by human iPSC-derived NK cells
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      DOI: 10.1016/j.stem.2024.06.009

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      DOI: 10.1016/j.stem.2024.06.009

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    cell.com/cell-stem-cell/abstract/S1934-5909(24)00217-0
  43. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Generation and characterization of inducible KRAB-dCas9 iPSCs from primates for cross-species CRISPRi
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      DOI: 10.1016/j.isci.2024.110090

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    ncbi.nlm.nih.gov/pmc/articles/PMC11214527/
  44. Jun 2024
  45. physoc.onlinelibrary.wiley.com physoc.onlinelibrary.wiley.com
    Aquaporin-4 deletion leads to reduced infarct volume and increased peri-infarct astrocyte reactivity in a mouse model of cortical stroke
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    1. scibot 28 Jun 2024
      AB_772

      DOI: 10.1113/JP284099

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    physoc.onlinelibrary.wiley.com/doi/10.1113/JP284099
  46. www.sciencedirect.com www.sciencedirect.com
    MTFP1 controls mitochondrial fusion to regulate inner membrane quality control and maintain mtDNA levels
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    1. scibot 21 Jun 2024
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      DOI: 10.1016/j.cell.2024.05.017

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    sciencedirect.com/science/article/pii/S0092867424005269
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    Biochemical characterization of renal hypouricemia-associated mutations in urate transporter genes using human cells
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    Viral infection disrupts intestinal homeostasis via Sting-dependent NF-κB signaling in Drosophila
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  49. May 2024
  50. www.cell.com www.cell.com
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    A conserved site on Ndc80 complex facilitates dynamic recruitment of Mps1 to yeast kinetochores to promote accurate chromosome segregation
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    Functional characterization of variants in human ABCC11, an axillary osmidrosis risk factor
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    The RIPK1 death domain restrains ZBP1- and TRIF-mediated cell death and inflammation
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    Prolactin blood concentration relies on scalability of the TIDA neurons' network efficiency in vivo.
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    The MYCN oncoprotein is an RNA-binding accessory factor of the nuclear exosome targeting complex
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    Methylation of the chromatin modifier KMT2D by SMYD2 contributes to therapeutic response in hormone-dependent breast cancer
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  58. elifesciences.org elifesciences.org
    Septin 7 interacts with Numb to preserve sarcomere structural organization and muscle contractile function
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    Identification of a chromatin-bound ERRα interactome network in mouse liver
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  60. Apr 2024
  61. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    P2X7 regulates ependymo-radial glial cell proliferation in adult Danio rerio following spinal cord injury
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  62. www.sciencedirect.com www.sciencedirect.com
    Reversible S-nitrosylation of bZIP67 by peroxiredoxin IIE activity and nitro-fatty acids regulates the plant lipid profile
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    A validation strategy to assess the role of phase separation as a determinant of macromolecular localization
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    ICAM-1 nanoclusters regulate hepatic epithelial cell polarity by leukocyte adhesion-independent control of apical actomyosin
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  65. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Identification of a chromatin-bound ERRα interactome network in mouse liver
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  66. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Restored glyoxylate metabolism after AGXT gene correction and direct reprogramming of primary hyperoxaluria type 1 fibroblasts
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  67. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    RAD51 separation of function mutation disables replication fork maintenance but preserves DSB repair
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    A rewiring of DNA replication mediated by MRE11 exonuclease underlies primed-to-naive cell de-differentiation
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    BAI1 localizes AMPA receptors at the cochlear afferent post-synaptic density and is essential for hearing
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  70. Mar 2024
  71. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Long noncoding RNA Malat1 protects against osteoporosis and bone metastasis
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  72. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    TREX2 deficiency suppresses spontaneous and genotoxin-associated mutagenesis
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    Downregulation of Dickkopf-3, a Wnt antagonist elevated in Alzheimer's disease, restores synapse integrity and memory in a disease mouse model
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  74. Feb 2024
  75. aacrjournals.org aacrjournals.org
    Engagement of CD99 activates distinct programs in Ewing sarcoma and macrophages
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  76. aacrjournals.org aacrjournals.org
    Nuclear GRP78 Promotes Metabolic Reprogramming and Therapeutic Resistance in Pancreatic Ductal Adenocarcinoma
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  77. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Adhesion-clutch between DCC and netrin-1 mediates netrin-1–induced axonal haptotaxis
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  78. link.springer.com link.springer.com
    Neuronal nitric oxide synthase positive neurons in the human corpus callosum: a possible link with the callosal blood-oxygen-level dependent (BOLD) effect
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  79. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Myeloid/natural killer (NK) cell precursor acute leukemia as a distinct leukemia type
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  80. www.biorxiv.org www.biorxiv.org
    Mechanical Netrin-1-DCC Coupling Mediates Netrin-1–induced Axonal Haptotaxis
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  81. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    EBAG9-deficient mice display decreased bone mineral density with suppressed autophagy
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  82. www.sciencedirect.com www.sciencedirect.com
    β1 integrin mediates unresponsiveness to PI3Kα inhibition for radiochemosensitization of 3D HNSCC models
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    Development of sexual dimorphism of skeletal muscles through the adrenal cortex, caused by androgen-induced global gene suppression
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  84. Jan 2024
  85. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Chemogenetic activation of PVN CRH neurons disrupts the estrous cycle and LH dynamics in female mice
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    IL32 downregulation lowers triglycerides and type I collagen in di-lineage human primary liver organoids
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  87. www.science.org www.science.org
    Myeloid/natural killer (NK) cell precursor acute leukemia as a distinct leukemia type
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    Pioneer and PRDM transcription factors coordinate bivalent epigenetic states to safeguard cell fate
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    The FANCI/FANCD2 complex links DNA damage response to R-loop regulation through SRSF1-mediated mRNA export
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  90. www.biorxiv.org www.biorxiv.org
    M4-mediated cholinergic transmission is reduced in parkinsonian mice and its restoration alleviates motor deficits and levodopa-induced dyskinesia
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  91. Dec 2023
  92. aacrjournals.org aacrjournals.org
    Dormant SOX9-Positive Cells Facilitate MYC-Driven Recurrence of Medulloblastoma
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      DOI: 10.1158/0008-5472.CAN-22-2108

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  93. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    VE-cadherin junction dynamics in initial lymphatic vessels promotes lymph node metastasis
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  94. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Casein kinase-2 inhibition promotes retinal ganglion cell survival after acute intraocular pressure elevation
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  95. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Inhibition of lipid synthesis by the HIV integrase strand transfer inhibitor elvitegravir in primary rat oligodendrocyte cultures
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  96. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A protocol to investigate the effects of lncRNAs on in vivo protein-protein interactions using proximity ligation assay
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  97. www.sciencedirect.com www.sciencedirect.com
    ALK inhibitors increase ALK expression and sensitize neuroblastoma cells to ALK.CAR-T cells
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  98. link.springer.com link.springer.com
    Streptozotocin-Induced Diabetic Rats Showed a Differential Glycine Receptor Expression in the Spinal Cord: A GlyR Role in Diabetic Neuropathy
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  99. Nov 2023
  100. www.sciencedirect.com www.sciencedirect.com
    Copine-6 is a Ca2+ sensor for activity-induced AMPA receptor exocytosis
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    PIM1 targeted degradation prevents the emergence of chemoresistance in prostate cancer
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  102. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SARS-CoV-2 hijacks a cell damage response, which induces transcription of a more efficient Spike S-acyltransferase
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  103. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Antitumor effects of PRMT5 inhibition in sarcomas
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  104. Oct 2023
  105. www.sciencedirect.com www.sciencedirect.com
    PAICS ubiquitination recruits UBAP2 to trigger phase separation for purinosome assembly
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    Proteomic profiling of centrosomes across multiple mammalian cell and tissue types by an affinity capture method
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  107. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    WIP1 is a novel specific target for growth hormone action
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  109. www.sciencedirect.com www.sciencedirect.com
    TERRA R-loops connect and protect sister telomeres in mitosis
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    CDK19 and CDK8 Mediator kinases drive androgen-independent in vivo growth of castration-resistant prostate cancer
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  111. 52.53.155.43 52.53.155.43
    ASCL1-ERK1/2 Axis: ASCL1 restrains ERK1/2 via the dual specificity phosphatase DUSP6 to promote survival of a subset of neuroendocrine lung cancers
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  112. www.sciencedirect.com www.sciencedirect.com
    DNA damage induces nuclear envelope rupture through ATR-mediated phosphorylation of lamin A/C
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  113. Sep 2023
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    Glutamate transporter contribution to retinal ganglion cell vulnerability in a rat model of multiple sclerosis
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    Antibodies targeting a quaternary site on SARS-CoV-2 spike glycoprotein prevent viral receptor engagement by conformational locking
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    Tff2 defines transit-amplifying pancreatic acinar progenitors that lack regenerative potential and are protective against Kras-driven carcinogenesis
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  117. www.embopress.org www.embopress.org
    The fruit fly acetyltransferase chameau promotes starvation resilience at the expense of longevity
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  118. Aug 2023
  119. www.sciencedirect.com www.sciencedirect.com
    High-throughput functional characterization of combinations of transcriptional activators and repressors
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  120. Jul 2023
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    Aurora A polyubiquitinates the BRCA1-interacting protein OLA1 to promote centrosome maturation
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  122. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Loss of STING in parkin mutant flies suppresses muscle defects and mitochondria damage
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  123. www.sciencedirect.com www.sciencedirect.com
    A p53/LINC00324 positive feedback loop suppresses tumor growth by counteracting SET-mediated transcriptional repression
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    Copine-6 is a Ca2+ sensor for activity-induced AMPA receptor exocytosis
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  125. 52.53.155.43 52.53.155.43
    Reduced histone gene copy number disrupts Drosophila Polycomb function
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  126. www.cell.com www.cell.com
    Fetal manipulation of maternal metabolism is a critical function of the imprinted Igf2 gene
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  127. www.embopress.org www.embopress.org
    Centrosome amplification fine tunes tubulin acetylation to differentially control intracellular organization
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  128. 52.53.155.43 52.53.155.43
    Inhibition of GPR120 signaling in intestine ameliorates insulin resistance and fatty liver under high-fat diet feeding
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  129. journals.physiology.org journals.physiology.org
    Inhibition of GPR120 signaling in intestine ameliorates insulin resistance and fatty liver under high-fat diet feeding
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  130. Jun 2023
  131. www.sciencedirect.com www.sciencedirect.com
    SVCT2/SLC23A2 is a sodium-dependent urate transporter: functional properties and practical application
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  132. www.nature.com www.nature.com
    Extracellular vesicle-associated IGF2BP3 tunes Ewing sarcoma cell migration and affects PI3K/Akt pathway in neighboring cells
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  133. www.sciencedirect.com www.sciencedirect.com
    Peptide-mediated inhibition of the transcriptional regulator Elongin BC induces apoptosis in cancer cells
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    Culture conditions of mouse ESCs impact the tumor appearance in vivo
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  135. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    KIF4 regulates neuronal morphology and seizure susceptibility via the PARP1 signaling pathway
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      DOI: 10.1083/jcb.202208108

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    Mettl14-mediated m6A modification ensures the cell-cycle progression of late-born retinal progenitor cells
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  138. 52.53.155.43 52.53.155.43
    Hypothalamic PVN CRH neurons signal through PVN GABA neurons to suppress GnRH pulse generator frequency in female mice
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      DOI: 10.1210/endocr/bqad075

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  139. May 2023
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    An isoform of the giant protein titin is a master regulator of human T lymphocyte trafficking
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    Unexpected plasma gonadal steroid and prolactin levels across the mouse estrous cycle
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    Protein quality control machinery supports primary ciliogenesis by eliminating GDP-bound Rab8-family GTPases
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    Ubiquitin proteomics identifies RNA polymerase I as a target of the Smc5/6 complex
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  144. Apr 2023
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    Stress granule formation inhibits stress-induced apoptosis by selectively sequestering executioner caspases
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  146. www.biorxiv.org www.biorxiv.org
    Reduced histone gene copy number disrupts Drosophila Polycomb function
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    N-acetylcysteine overcomes NF1 loss-driven resistance to PI3Kα inhibition in breast cancer
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  148. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    TZAP overexpression induces telomere dysfunction and ALT-like activity in ATRX/DAXX deficient cells
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  149. Mar 2023
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    TZAP overexpression induces telomere dysfunction and ALT-like activity in ATRX/DAXX deficient cells
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    Large neutral amino acid levels tune perinatal neuronal excitability and survival
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    Role of posterodorsal medial amygdala urocortin-3 in pubertal timing in female mice
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    Stepwise activities of mSWI/SNF family chromatin remodeling complexes direct T cell activation and exhaustion
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    Activation of AMP-activated protein kinase (AMPK) through inhibiting interaction with prohibitins
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    Harnessing transcriptionally driven chromosomal instability adaptation to target therapy-refractory lethal prostate cancer
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  156. Feb 2023
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    Loss of C9orf72 perturbs the Ran-GTPase gradient and nucleocytoplasmic transport, generating compositionally diverse Importin β-1 granules
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    IGF-binding proteins secreted by cancer-associated fibroblasts induce context-dependent drug sensitization of lung cancer cells
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    Molecular basis of eIF5A-dependent CAT tailing in eukaryotic ribosome-associated quality control
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    Development of a bispecific DNA-aptamer-based lysosome-targeting chimera for HER2 protein degradation
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    Asparagine and Glutamine Deprivation Alters Ionizing Radiation Response, Migration and Adhesion of a p53null Colorectal Cancer Cell Line
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  162. Jan 2023
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    Peptides from human BNIP5 and PXT1 and non-native binders of pro-apoptotic BAK can directly activate or inhibit BAK-mediated membrane permeabilization
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    Interleukin 11 confers resistance to dextran sulfate sodium-induced colitis in mice
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    Protocol for the analysis of double-stranded RNAs in virus-infected insect cells using anti-dsRNA antibodies
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    The interferon stimulated gene-encoded protein HELZ2 inhibits human LINE-1 retrotransposition and LINE-1 RNA-mediated type I interferon induction
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    Use of metabolic glycoengineering and pharmacological inhibitors to assess lipid and protein sialylation on cells
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    Functional partitioning of transcriptional regulators by patterned charge blocks
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    Decreasing mutant ATXN1 nuclear localization improves a spectrum of SCA1-like phenotypes and brain region transcriptomic profiles
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  170. Dec 2022
  171. academic.oup.com academic.oup.com
    Posterodorsal Medial Amygdala Urocortin-3, GABA, and Glutamate Mediate Suppression of LH Pulsatility in Female Mice
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    AKTIP loss is enriched in ERα-positive breast cancer for tumorigenesis and confers endocrine resistance
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    The oncogenic PI3K-induced transcriptomic landscape reveals key functions in splicing and gene expression regulation
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    Neuronal nitric oxide synthase positive neurons in the human corpus callosum: a possible link with the callosal blood-oxygen-level dependent (BOLD) effect
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    Optogenetic stimulation of Kiss1ARC terminals in the AVPV induces surge-like luteinizing hormone secretion via glutamate release in mice
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  176. Nov 2022
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    Heat shock protein amplification improves cerebellar myelination in the Npc1nih mouse model
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    Double knockin mice show NF-κB trajectories in immune signaling and aging
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    Chronic Trazodone and Citalopram Treatments Increase Trophic Factor and Circadian Rhythm Gene Expression in Rat Brain Regions Relevant for Antidepressant Efficacy
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  180. www.cell.com www.cell.com
    Hypothalamic orexin prevents non-alcoholic steatohepatitis and hepatocellular carcinoma in obesity
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    ATG9A and ATG2A form a heteromeric complex essential for autophagosome formation
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    The target antigen determines the mechanism of acquired resistance to T cell-based therapies
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  183. Oct 2022
  184. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The Global Protein-RNA Interaction map of ESRP1 defines a post-transcriptional program that is essential for epithelial cell function
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  185. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    BK Polyomavirus Requires the Mismatch Repair Pathway for DNA Damage Response Activation
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    KIF3B promotes a PI3K signaling gradient causing changes in a Shh protein gradient and suppressing polydactyly in mice
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  187. Sep 2022
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    ER-Golgi-localized proteins TMED2 and TMED10 control the formation of plasma membrane lipid nanodomains
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    Effects of Chronic Kidney Disease on Nanomechanics of the Endothelial Glycocalyx Are Mediated by the Mineralocorticoid Receptor
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    Provocative tests with Kisspeptin-10 and GnRH set the scene for determining social status and environmental impacts on reproductive capacity in male African lions (Panthera leo)
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    Aversive memory reactivation: A possible role for delta oscillations in the hippocampus–amygdala circuit
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    Sensing of individual stalled 80S ribosomes by Fap1 for nonfunctional rRNA turnover
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    In vivo characterization of Drosophila golgins reveals redundancy and plasticity of vesicle capture at the Golgi apparatus
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    Integrated multi-omics analysis of adverse cardiac remodeling and metabolic inflexibility upon ErbB2 and ERRα deficiency
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    A next-generation iPSC-derived forebrain organoid model of tauopathy with tau fibrils by AAV-mediated gene transfer
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    Sublethal cytochrome c release generates drug-tolerant persister cells
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    Satellite glia modulate sympathetic neuron survival, activity, and autonomic function
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  198. Aug 2022
  199. 52.53.155.43 52.53.155.43
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    Host and microbiome features of secondary infections in lethal covid-19
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    Identification of the NRF2 transcriptional network as a therapeutic target for trigeminal neuropathic pain
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    Rap1 controls epiblast morphogenesis in sync with the pluripotency states transition
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    A druggable addiction to de novo pyrimidine biosynthesis in diffuse midline glioma
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    SARS-CoV-2 Delta spike protein enhances the viral fusogenicity and inflammatory cytokine production
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  205. Jul 2022
  206. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A non-transcriptional function of Yap regulates the DNA replication program in Xenopus laevis
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    High-risk neuroblastoma with NF1 loss of function is targetable using SHP2 inhibition
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    Varicella‐Zoster virus ORF9 is an antagonist of the DNA sensor cGAS
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  209. Jun 2022
  210. 52.53.155.43 52.53.155.43
    Control of coronary vascular resistance by eicosanoids via a novel GPCR
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    Engineering yeast to induce the synthesis of GPI-APs with a permanent phosphoethanolamine on mannose 2 of the glycan moiety
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    Identifying enhancers of innate immune signaling as broad-spectrum antivirals active against emerging viruses
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    Visualization of the dynamic interaction between nucleosomal histone H3K9 tri-methylation and HP1α chromodomain in living cells
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    Invading viral DNA triggers dsRNA synthesis by RNA polymerase II to activate antiviral RNA interference in Drosophila
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    The type V myosin-containing complex HUM is a RAB11 effector powering movement of secretory vesicles
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    CLASP2 safeguards hematopoietic stem cell properties during mouse and fish development
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    METTL18-mediated histidine methylation of RPL3 modulates translation elongation for proteostasis maintenance
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    Assembly checkpoint of the proteasome regulatory particle is activated by coordinated actions of proteasomal ATPase chaperones
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  219. May 2022
  220. www.jneurosci.org www.jneurosci.org
    Evolution Increases Primates Brain Complexity Extending RbFOX1 Splicing Activity to LSD1 Modulation
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    Redox-sensitive E2 Rad6 controls cellular response to oxidative stress via K63-linked ubiquitination of ribosomes
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    Postnatal expression of cell cycle promoter Fam64a causes heart dysfunction by inhibiting cardiomyocyte differentiation through repression of Klf15
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    The Taspase1/Myosin1f-axis regulates filopodia dynamics
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    Xist-mediated silencing requires additive functions of SPEN and Polycomb together with differentiation-dependent recruitment of SmcHD1
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  225. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Canonical Bone Morphogenetic Protein Signaling Regulates Expression of Aquaporin-4 and Its Anchoring Complex in Mouse Astrocytes
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    Retinoic acid-induced protein 14 controls dendritic spine dynamics associated with depressive-like behaviors
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  227. elifesciences.org elifesciences.org
    Enhanced C/EBPβ function promotes hypertrophic versus hyperplastic fat tissue growth and prevents steatosis in response to high-fat diet feeding
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