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127 Matching Annotations

Sep 2026
dx.doi.org dx.doi.org

TNFR1 expression on cancer cells mediates immune escape and an immunosuppressive microenvironment

1
1. scibot 12 Sep 2026
  
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  RRID:CVCL_7254
  
  DOI: 10.1084/jem.20252080
  
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dx.doi.org/10.1084/jem.20252080
www.nature.com www.nature.com

Dopamine polymerization-mediated surface functionalization of living cells for advanced therapeutic applications

1
1. scibot 11 Sep 2026
  
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  RRID:CVCL_7254
  
  DOI: 10.1038/s41596-026-01422-1
  
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nature.com/articles/s41596-026-01422-1
www.sciencedirect.com www.sciencedirect.com

PPM1L-dependent PD-L1 dephosphorylation orchestrates tumor-type-specific ubiquitin ligase recognition to govern its degradation

1
1. scibot 09 Sep 2026
  
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  RRID:CVCL_7254
  
  DOI: 10.1016/j.celrep.2026.117955
  
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sciencedirect.com/science/article/pii/S2211124726010338
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Coordinated Immune Activation Following KRAS Inhibition in Syngeneic Models Reveals Molecular Pathways that Potentiate and Limit Antitumor Immunity

1
1. scibot 04 Sep 2026
  
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  RRID:CVCL_7254
  
  DOI: 10.1158/2326-6066.CIR-25-0794
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13535328/
Aug 2026
dx.doi.org dx.doi.org

Temporal Immunomodulation via Methylation Epigenetics Counteracts Immune Evasion by Expanding the Time Window

1
1. scibot 20 Aug 2026
  
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  RRID:CVCL_7254
  
  DOI: 10.1021/acsnano.6c05479
  
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dx.doi.org/10.1021/acsnano.6c05479
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Targeted phenylboronic acid-rosuvastatin based nanoconstructs: A novel therapeutic avenue for treatment of colorectal cancer

1
1. scibot 12 Aug 2026
  
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  RRID:CVCL_7254
  
  DOI: 10.1016/j.nano.2026.103005
  
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sciencedirect.com/science/article/pii/S1549963426001061
onlinelibrary.wiley.com onlinelibrary.wiley.com

GPR39 Suppresses Ferroptosis via the Nrf2/SLC7A11 Axis and Reduces the Sensitivity of Colorectal Cancer to Anti-PD-1 Immunotherapy

1
1. scibot 11 Aug 2026
  
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  RRID: CVCL_7254
  
  DOI: 10.1155/cjgh/5689742
  
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  Curator: @nmaralla
  
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onlinelibrary.wiley.com/doi/10.1155/cjgh/5689742
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Iron-addicted colorectal cancers exploit heme-complex II axis to resist oxidative cell death

1
1. scibot 01 Aug 2026
  
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  CT26
  
  DOI: 10.1016/j.cmet.2026.04.020
  
  Resource: (KCLB Cat# 80009, RRID:CVCL_7254)
  
  Curator: @evieth
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13401815/
Jul 2026
aacrjournals.org aacrjournals.org

Mutant KRAS Suppresses DNA Sensing by Remodeling Membrane Tension to Clear Extracellular Tumor DNA

1
1. scibot 21 Jul 2026
  
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  CVCL_7254
  
  DOI: 10.1158/0008-5472.CAN-25-4447
  
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aacrjournals.org/cancerres/article/86/14/3394/786575/Mutant-KRAS-Suppresses-DNA-Sensing-by-Remodeling
54.241.53.176 54.241.53.176

can-25-3935-html.html

1
1. scibot 21 Jul 2026
  
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  RRID:CVCL_7254
  
  DOI: 10.1158/0008-5472.can-25-3935
  
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54.241.53.176/979888a1f7761ae1ca9da94ae777c2647822eb31/can-25-3935-html.html
www.sciencedirect.com www.sciencedirect.com

SOCS5 suppresses antitumor immunity in colorectal cancer by promoting IFNAR1 ubiquitylation and type I interferon response

1
1. scibot 15 Jul 2026
  
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  RRID:CVCL_7254
  
  DOI: 10.1016/j.bbadis.2026.168367
  
  Resource: (KCLB Cat# 80009, RRID:CVCL_7254)
  
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sciencedirect.com/science/article/pii/S0925443926002309
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Mucosal-associated invariant T cells recognize a tumor-derived metabolite in the DNA synthesis pathway

1
1. scibot 12 Jul 2026
  
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  RRID:CVCL_7254
  
  DOI: 10.3389/fimmu.2026.1797918
  
  Resource: (KCLB Cat# 80009, RRID:CVCL_7254)
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13342176/
54.241.53.176 54.241.53.176

Combining PD-L1 blockade with a second-generation HSP110 inhibitor enhances antitumor immunity in colorectal cancer

1
1. scibot 11 Jul 2026
  
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  RRID:CVCL_7254
  
  DOI: 10.1038/s41419-026-08826-7
  
  Resource: (KCLB Cat# 80009, RRID:CVCL_7254)
  
  Curator: @areedewitt04
  
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54.241.53.176/7fba9f32795d3fd188709e6b4cbf7163473ee228/s41419-026-08826-7_reference-html.html
advanced.onlinelibrary.wiley.com advanced.onlinelibrary.wiley.com

Temporal Immune and Metabolic Shifts Drive the Anti-Tumor Efficacy of Resiquimod-Loaded Nanoparticles in Peritoneal Carcinomatosis

1
1. scibot 11 Jul 2026
  
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  RRID:CVCL_7254
  
  DOI: 10.1002/adhm.71424
  
  Resource: (KCLB Cat# 80009, RRID:CVCL_7254)
  
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advanced.onlinelibrary.wiley.com/doi/10.1002/adhm.71424
Jun 2026
www.sciencedirect.com www.sciencedirect.com

Design optimization of antibody-ligand motifs to enhance CAR-T redirection activity against solid tumors

1
1. scibot 26 Jun 2026
  
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  RRID:CVCL_7254
  
  DOI: 10.1016/j.xcrm.2026.102885
  
  Resource: (KCLB Cat# 80009, RRID:CVCL_7254)
  
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sciencedirect.com/science/article/pii/S2666379126003022
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Nanoparticulate Immunoactive Complex for Local Chemoimmunotherapy: From Murine Models to Pilot Canine Study

1
1. scibot 25 Jun 2026
  
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  RRID:CVCL_7254
  
  DOI: 10.1158/2767-9764.CRC-26-0110
  
  Resource: (KCLB Cat# 80009, RRID:CVCL_7254)
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13285167/
onlinelibrary.wiley.com onlinelibrary.wiley.com

Two New Citrinin Derivatives From the Marine Sponge-Derived Fungus Aspergillus sp. S4I4-4

1
1. scibot 23 Jun 2026
  
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  RRID:CVCL_7254
  
  DOI: 10.1002/cbdv.71442
  
  Resource: (KCLB Cat# 80009, RRID:CVCL_7254)
  
  Curator: @scibot
  
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onlinelibrary.wiley.com/doi/10.1002/cbdv.71442
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

PI3K and MAPK Signaling Nodes Serve as Divergent Drivers of Phenotypic Plasticity in Cancer-Associated Fibroblasts in Colorectal Cancer

1
1. scibot 17 Jun 2026
  
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  RRID:CVCL_7254
  
  DOI: 10.1158/0008-5472.CAN-25-0766
  
  Resource: (KCLB Cat# 80009, RRID:CVCL_7254)
  
  Curator: @scibot
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13266349/
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

DDR1 Promotes Immune Evasion in Colorectal Cancer by Orchestrating IL33-Mediated M2-like Polarization of Tumor-Associated Macrophages

1
1. scibot 05 Jun 2026
  
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  RRID: CVCL_7254
  
  DOI: 10.1158/2326-6066.CIR-25-1073
  
  Resource: (KCLB Cat# 80009, RRID:CVCL_7254)
  
  Curator: @evieth
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13227095/
link.springer.com link.springer.com

Exploring Synergistic Potential of Sorafenib and Atorvastatin to Launch Apoptosis and Ferroptosis-driven Mixed Cell Death Mechanism in Colorectal Cancer

1
1. scibot 04 Jun 2026
  
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  RRID:CVCL_7254
  
  DOI: 10.1208/s12249-026-03461-z
  
  Resource: (KCLB Cat# 80009, RRID:CVCL_7254)
  
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link.springer.com/article/10.1208/s12249-026-03461-z
May 2026
www.sciencedirect.com www.sciencedirect.com

An HOCl-activated chemiluminescent prodrug enabling self-reporting camptothecin release and imaging-guided therapy in peritoneal metastasis

1
1. scibot 29 May 2026
  
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  RRID:CVCL_7254
  
  DOI: 10.1016/j.bmc.2026.118717
  
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sciencedirect.com/science/article/pii/S0968089626001732
onlinelibrary.wiley.com onlinelibrary.wiley.com

Sialylation in Colorectal Cancer Rewires Antitumor Immunity at the Peritoneal Metastatic Site

1
1. scibot 21 May 2026
  
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  RRID:CVCL_7254
  
  DOI: 10.1002/eji.70204
  
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onlinelibrary.wiley.com/doi/10.1002/eji.70204
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Preclinical Characterization and Clinical Activity of RNK08954, a Highly Selective and Orally Bioavailable KRAS G12D Inhibitor

1
1. scibot 05 May 2026
  
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  RRID:CVCL_7254
  
  DOI: 10.1158/2159-8290.CD-25-1346
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13133609/
Apr 2026
54.241.53.176 54.241.53.176

cd-25-1346-html.html

1
1. scibot 23 Apr 2026
  
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  RRID:CVCL_7254
  
  DOI: 10.1158/2159-8290.CD-25-1346
  
  Resource: (KCLB Cat# 80009, RRID:CVCL_7254)
  
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54.241.53.176/86f1cde136cae9cb2b05401d7da6d7a0a1acbc52/cd-25-1346-html.html
aacrjournals.org aacrjournals.org

Tumor cell-derived microparticles induced by methotrexate reprogram neutrophil antitumor response via lysosomal ROS mediated degranulation

1
1. scibot 23 Apr 2026
  
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  RRID:CVCL_7254
  
  DOI: 10.1158/1541-7786.MCR-25-0615
  
  Resource: (KCLB Cat# 80009, RRID:CVCL_7254)
  
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aacrjournals.org/mcr/article/24/4/293/775480/Tumor-Cell-Derived-Microparticles-Induced-by
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Tumor metabolic adaptation induced by L-asparaginase reveals a vulnerability to PARP1/2 inhibitor in B-cell lymphomas

1
1. scibot 15 Apr 2026
  
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  CT26
  
  DOI: 10.1038/s41467-026-70066-2
  
  Resource: (KCLB Cat# 80009, RRID:CVCL_7254)
  
  Curator: @evieth
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13065833/
54.241.53.176 54.241.53.176

A Fully Human Pan VL9 HLAE TCRm Antibody Enables Functional Dissection of HLAE Biology and Checkpoint Signaling

2
1. scibot 11 Apr 2026
  
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  CVCL_7254
  
  DOI: 10.1016/j.isci.2026.115669
  
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2. scibot 10 Apr 2026
  
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  CVCL_7254
  
  DOI: 10.1016/j.isci.2026.115669
  
  Resource: (KCLB Cat# 80009, RRID:CVCL_7254)
  
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54.241.53.176/089c0d54aafa939862e15036a250ae2fa17f1db6/1-s2.0-S2589004226010448-main-html.html
advanced.onlinelibrary.wiley.com advanced.onlinelibrary.wiley.com

Ammonia Detoxification Inhibits Liver Metastasis by Reshaping Hepatic Microenvironment

1
1. scibot 10 Apr 2026
  
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  RRID: CVCL_7254
  
  DOI: 10.1002/advs.202521098
  
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  Curator: @dhovakimyan1
  
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advanced.onlinelibrary.wiley.com/doi/full/10.1002/advs.202521098
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

All‐PEG‐Like Block Copolymers Self‐Assemble into Stealth Nanocarriers for Drug Delivery

1
1. scibot 03 Apr 2026
  
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  RRID:CVCL_7254
  
  DOI: 10.1002/advs.202517048
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13042870/
pubs.acs.org pubs.acs.org

Dual-Targeting mRNA Cancer Vaccines for Simultaneous Antigen Presentation in Dendritic and Tumor Cells

1
1. scibot 02 Apr 2026
  
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  RRID:CVCL_7254
  
  DOI: 10.1021/acsnano.5c20535
  
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pubs.acs.org/doi/10.1021/acsnano.5c20535
advanced.onlinelibrary.wiley.com advanced.onlinelibrary.wiley.com

EEPD1 Inhibition Unleashes Antitumor Immunity in Colorectal Cancer by Activating the cGAS-STING Pathway

1
1. scibot 02 Apr 2026
  
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  RRID:CVCL_7254
  
  DOI: 10.1002/advs.202522826
  
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advanced.onlinelibrary.wiley.com/doi/10.1002/advs.202522826
advanced.onlinelibrary.wiley.com advanced.onlinelibrary.wiley.com

Oral Streptococcus salivarius Couples Neutrophil IRGM1 Signaling to NET Formation and Colorectal Cancer Metastasis

1
1. scibot 02 Apr 2026
  
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  RRID:CVCL_7254
  
  DOI: 10.1002/advs.202516546
  
  Resource: (KCLB Cat# 80009, RRID:CVCL_7254)
  
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advanced.onlinelibrary.wiley.com/doi/10.1002/advs.202516546
Mar 2026
www.sciencedirect.com www.sciencedirect.com

Lipid nanoparticle used in mRNA vaccine promotes tumor metastasis in mouse model via mtDNA-induced neutrophil activation and NETosis

1
1. scibot 31 Mar 2026
  
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  RRID:CVCL_7254
  
  DOI: 10.1016/j.nantod.2026.103039
  
  Resource: (KCLB Cat# 80009, RRID:CVCL_7254)
  
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sciencedirect.com/science/article/pii/S1748013226000666
advanced.onlinelibrary.wiley.com advanced.onlinelibrary.wiley.com

Reinforcing Calcium Overload via Inflammation-Mediated Targeting to Amplify Pyroptosis and Antitumor Immunity

1
1. scibot 31 Mar 2026
  
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  RRID:CVCL_7254
  
  DOI: 10.1002/advs.202522827
  
  Resource: (KCLB Cat# 80009, RRID:CVCL_7254)
  
  Curator: @scibot
  
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Quantification of Single‐Cell Cysteine Using an Electrochemical Nanosensor for Predicting Tumor Disulfidptosis Susceptibility

1
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  RRID: CVCL_7254
  
  DOI: 10.1002/advs.202523478
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12955924/
Feb 2026
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Modulating the tumor immune phenotypes by radiotherapy: formulating and validating the combination therapy of radiation, PD-L1, and TIM-3 blockade in colorectal cancer

1
1. scibot 27 Feb 2026
  
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  RRID:CVCL_7254
  
  DOI: 10.1136/jitc-2025-013656
  
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Selective Targeting of Tip Endothelial Cells as a Therapeutic Strategy for Tumor Angiogenesis

1
1. scibot 26 Feb 2026
  
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  DOI: 10.1002/advs.202512975
  
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An Electrochemical Biosensor for Detecting Calreticulin In Situ to Assess Immunogenic Cell Death in Tumor Cells

1
1. scibot 19 Feb 2026
  
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  DOI: 10.1021/acs.analchem.5c08068
  
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EREG promotes colorectal cancer progression and immune suppressive microenvironment formation through IL-17A/NF-κB pathway

1
1. scibot 19 Feb 2026
  
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  DOI: 10.1007/s12672-026-04466-7
  
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Colorectal cancer-derived osteopontin rewires macrophages into a pro-metastatic M2 state via the PI3K/AKT/CSF1-CSF1R axis

1
1. scibot 14 Feb 2026
  
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  DOI: 10.1038/s41420-026-02945-y
  
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The Microbial Bile Acid Metabolite 3-oxo-LCA Inhibits Colorectal Cancer Progression

1
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FAPα+ Macrophages Orchestrate Immune Evasion in Multiple Myeloma by Dual Regulation of PD-L1 and T Cell Senescence

1
1. scibot 06 Feb 2026
  
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  DOI: 10.1002/advs.202506239
  
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Phillygenin regulates the colorectal cancer tumor microenvironment by inhibiting hypoxia-inducible factor 1 alpha

1
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The lipid-metabolic enzyme HSD17B12 drives lysosomal degradation of PD-L1 potentiating anti-tumor immunity in a mouse model

1
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  DOI: 10.1371/journal.pbio.3003603
  
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Jan 2026
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Thimerosal Inhibits Tumor Malignant Progression through Direct Action and Enhancing the Efficacy of PD-1-Based Immunotherapy

1
1. scibot 30 Jan 2026
  
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Integrative Multiscale Analysis Reveals EFNA1‐Driven Immune Remodeling Promotes Colorectal Cancer Lymph Node Metastasis

1
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USP35 Acts as a Deubiquitinating Enzyme for ID3 to Promote Immune Escape in Colorectal Cancer

1
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Dec 2025
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A novel β-carboline alkaloid derivative targeting MDM2-p53 pathway suppresses colorectal cancer progression

1
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The KDM6B/SLC10A2 Axis Suppresses MDSCs Recruitment via ERK/AP-1 Signaling in Colorectal Cancer

1
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Nov 2025
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Effect of extracellular vesicles in remodeling the tumor microenvironment by DNMT1 downregulation for enhanced cancer immunotherapy

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  DOI: 10.1136/jitc-2025-012138
  
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StealTHY: An immunogen-free CRISPR platform to expose concealed metastasis regulators in immunocompetent models

1
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  DOI: 10.1016/j.cell.2025.10.007
  
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sciencedirect.com/science/article/pii/S0092867425011365
Oct 2025
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Enhancement of antitumor immunity by CTLA-4 antisense oligonucleotides with CpG motif in mice

1
1. scibot 15 Oct 2025
  
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  DOI: 10.1016/j.intimp.2025.115648
  
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Zuojin Wan Suppresses the Progression of Colorectal Cancer by Inhibiting M2 Tumor-Associated Macrophages Through JAK2/STAT3 Signaling Pathway and In Vivo and In Vitro

1
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Zuojin Wan Suppresses the Progression of Colorectal Cancer by Inhibiting M2 Tumor-Associated Macrophages Through JAK2/STAT3 Signaling Pathway and In Vivo and In Vitro

1
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Sep 2025
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Dual STING activation and CD47/SIRPα blockade via chitooligosaccharide-based nanoparticles to amplify antitumor immunity

1
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Discovery of BMS-986408, a First-In-Class Dual DGKα and DGKζ Inhibitor that Unleashes PD-1 Checkpoint and CAR T-cell Immunotherapies

1
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A Pan-RAS Inhibitor with a Unique Mechanism of Action Blocks Tumor Growth and Induces Antitumor Immunity in Gastrointestinal Cancer

1
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  DOI: 10.1158/0008-5472.CAN-24-0323
  
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Macrophages orchestrate elimination of Shigella from the intestinal epithelial cell niche via TLR-induced IL-12 and IFN-γ

1
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Inosine shapes PD-1 blockade responses and synergizes with dual PD-1/CTLA-4 immunotherapy to enhance antitumor immunity

1
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Lifespan-Regulated CAR-Macrophages from Myeloid Progenitors for Enhanced Colorectal Cancer Therapy

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  DOI: 10.1002/advs.202417677
  
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Novel Swelling-Lytic Cell Death Triggered by Cargo-Free Ionizable Lipid Nanoparticles

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  DOI: 10.1002/advs.202509208
  
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A pan-KRAS inhibitor and its derived degrader elicit multifaceted anti-tumor efficacy in KRAS-driven cancers

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  DOI: 10.1016/j.ccell.2025.07.006
  
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Tumor desialylation surpasses anti-PD-L1 checkpoint therapy in restoring anti-tumor immunity in a murine model for colorectal cancer

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A Pharmacokinetic and Pharmacodynamic Model of an IL-12 Anchored-Drug Conjugate for the Treatment of Solid Tumors

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  DOI: 10.1158/1535-7163.MCT-24-1051
  
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Low-dose radiotherapy enhances the efficacy of PD-L1 blockade and induces the abscopal effect

1
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pmc.ncbi.nlm.nih.gov/articles/PMC12211843/
Jun 2025
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Combination therapy with levofloxacin and the probiotic Clostridium butyricum MIYAIRI 588 enhances immune checkpoint inhibitor efficacy

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  RRID:CVCL_7254
  
  DOI: 10.1158/2326-6066.cir-24-0797
  
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May 2025
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Discovery and Characterization of a First-in-Class LIV1-TLR7/8 Immunomodulatory Conjugate with Robust Myeloid Activation and Antitumor Activity

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1. scibot 29 May 2025
  
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  DOI: 10.1021/acs.jmedchem.5c00264
  
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INBRX-106: a hexavalent OX40 agonist that drives superior antitumor responses via optimized receptor clustering

1
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  DOI: 10.1136/jitc-2025-011524
  
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NECTIN4 regulates the cell surface expression of CD155 in non-small cell lung cancer cells and induces tumor resistance to PD-1 inhibitors

1
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  DOI: 10.1007/s00262-025-04079-z
  
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Reducing Dietary Protein Enhances the Antitumor Effects of Chemotherapy through Immune-Mediated Mechanisms

1
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Combinatorial treatment with upadacitinib abrogates systemic toxicity of a tumor-targeted IL-2 fusion protein

1
1. scibot 20 May 2025
  
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Combination therapy with cetirizine and anti-PD-1 antibody suppresses colitis-induced colon tumor formation in mice

1
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Next-generation probiotics Alistipes onderdonkii enhances the efficacy of anti-PD-1 therapy in colorectal cancer

1
1. scibot 16 May 2025
  
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The E3 Ligase NEDD4L Prevents Colorectal Cancer Liver Metastasis via Degradation of PRMT5 to Inhibit the AKT/mTOR Signaling Pathway

1
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  DOI: 10.1002/advs.202504704
  
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Apr 2025
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Adenosine Uptake through the Nucleoside Transporter ENT1 Suppresses Antitumor Immunity and T Cell Pyrimidine Synthesis

1
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  DOI: 10.1158/0008-5472.CAN-24-1875
  
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Mar 2025
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PDF-html.html

1
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A targeted MAVS fusion protein for controlled innate immune activation and antitumor therapy

1
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  RRID:CVCL_7254
  
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Mechanism Study of Bufalin Reversal of Drug Resistance by Inhibiting Hypoxic Colon Cancer Cell-Induced Polarization of M2 Macrophages

1
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Feb 2025
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Targeted Delivery of TLR7 Agonists to the Tumor Microenvironment Enhances Tumor Immunity via Activation of Tumor-Resident Myeloid Cells

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  DOI: 10.1021/acs.bioconjchem.4c00534
  
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Serotonin receptor HTR2B facilitates colorectal cancer metastasis via CREB1-ZEB1 axis mediated epithelial-mesenchymal transition

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Dec 2024
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Spatial Context of Immune Checkpoints as Predictors of Overall Survival in Patients with Resectable Colorectal Cancer Independent of Standard Tumor–Node–Metastasis Stages

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Nov 2024
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crc-24-0270-html.html

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Overproduction of Gastrointestinal 5-HT Promotes Colitis-Associated Colorectal Cancer Progression via Enhancing NLRP3 Inflammasome Activation

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aacrjournals.org/cancerimmunolres/article/9/9/1008/666146/Overproduction-of-Gastrointestinal-5-HT-Promotes
Sep 2024
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Altered epitopes enhance macrophage-mediated anti-tumour immunity to low-immunogenic tumour mutations

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  DOI: 10.1111/imm.13854
  
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Ethanol promotes alcohol-related colorectal cancer metastasis via the TGF-β/RUNX3/Snail axis by inducing TGF-β1 upregulation and RUNX3 cytoplasmic mislocalization

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Opposing Functions of Interferon Coordinate Adaptive and Innate Immune Responses to Cancer Immune Checkpoint Blockade

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  DOI: 10.1016/j.cell.2019.07.019
  
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Pretargeted Radioimmunotherapy with the Novel Anti-oxMIF/HSG Bispecific Antibody ON105 Results in Significant Tumor Regression in Murine Models of Cancer

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IDO1 inhibitors are synergistic with CXCL10 agonists in inhibiting colon cancer growth

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Association of appendectomy with prognosis and tumor-associated macrophages in patients with colorectal cancer

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Aug 2024
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Tumor cell-expressed lipolysis-stimulated lipoprotein receptor negatively regulates T-cell function

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Molecular Oncology - 2023 - Pan-html.html

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Jul 2024
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The Tumor Microbiome Reacts to Hypoxia and Can Influence Response to Radiation Treatment in Colorectal Cancer

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  DOI: 10.1158/2767-9764.CRC-23-0367
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11234499/
Apr 2024
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Type I interferon regulation by USP18 is a key vulnerability in cancer

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  DOI: 10.1016/j.isci.2024.109593
  
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The immune suppressor IGSF1 as a potential target for cancer immunotherapy

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  DOI: 10.1158/2326-6066.CIR-23-0817
  
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XTX301, a Tumor-Activated Interleukin-12 Has the Potential to Widen the Therapeutic Index of IL12 Treatment for Solid Tumors as Evidenced by Preclinical Studies

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ncbi.nlm.nih.gov/pmc/articles/PMC10993987/
Feb 2024
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Anti-tumor immunotherapy using engineered bacterial outer membrane vesicles fused to lysosome-targeting chimeras mediated by transferrin receptor

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  DOI: 10.1016/j.chembiol.2024.01.002
  
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Nov 2023
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An engineered immunocytokine with collagen affinity improves the tumor bioavailability, tolerability, and therapeutic efficacy of IL-2

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  DOI: 10.1016/j.xcrm.2023.101289
  
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Anti-tumor effect of PD-L1-targeting antagonistic aptamer-ASO delivery system with dual inhibitory function in immunotherapy

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  DOI: 10.1016/j.chembiol.2023.10.010
  
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Sep 2023
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Loss of cancer cell-derived ADAM15 alters the tumor microenvironment in colorectal tumors

1
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  DOI: 10.1002/ijc.34695
  
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onlinelibrary.wiley.com/doi/full/10.1002/ijc.34695
Aug 2023
www.nature.com www.nature.com

Engineered E. coli Nissle 1917 for delivery of bioactive IL-2 for cancer immunotherapy

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1. scibot 03 Aug 2023
  
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  RRID:CVCL_7254
  
  DOI: 10.1038/s41598-023-39365-2
  
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nature.com/articles/s41598-023-39365-2
Jul 2023
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Comparison of the effects of probiotic strains (Lactobacillus gasseri, Lactiplantibacillus plantarum, Lactobacillus acidophilus, and Limosilactobacillus fermentum) isolated from human and food products on the immune response of CT26 tumor–bearing mice

1
1. scibot 13 Jul 2023
  
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  RRID:CVCL_7254
  
  DOI: 10.1007/s42770-023-01060-9
  
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link.springer.com/article/10.1007/s42770-023-01060-9
May 2023
www.nature.com www.nature.com

ERK and USP5 govern PD-1 homeostasis via deubiquitination to modulate tumor immunotherapy

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1. scibot 20 May 2023
  
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  RRID:CVCL_7254
  
  DOI: 10.1038/s41467-023-38605-3
  
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nature.com/articles/s41467-023-38605-3
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Venlafaxine antagonizes the noradrenaline-promoted colon cancer progression by inhibiting the norepinephrine transporter

1
1. scibot 10 May 2023
  
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  RRID:CVCL_7254
  
  DOI: 10.1038/s41420-023-01447-5
  
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nature.com/articles/s41420-023-01447-5
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Preclinical Evaluation of ON203, A Novel Bioengineered mAb Targeting Oxidized Macrophage Migration Inhibitory Factor as an Anticancer Therapeutic

1
1. scibot 06 May 2023
  
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  RRID:CVCL_7254
  
  DOI: 10.1158/1535-7163.MCT-22-0676
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10157364/
Apr 2023
aacrjournals.org aacrjournals.org

IOA-244 is a Non–ATP-competitive, Highly Selective, Tolerable PI3K Delta Inhibitor That Targets Solid Tumors and Breaks Immune Tolerance

1
1. scibot 19 Apr 2023
  
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  RRID:CVCL_7254
  
  DOI: 10.1158/2767-9764.CRC-22-0477
  
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aacrjournals.org/cancerrescommun/article/3/4/576/725855/IOA-244-is-a-Non-ATP-competitive-Highly-Selective
www.nature.com www.nature.com

Isolation of tumour-reactive lymphocytes from peripheral blood via microfluidic immunomagnetic cell sorting

1
1. scibot 11 Apr 2023
  
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  RRID:CVCL_7254
  
  DOI: 10.1038/s41551-023-01023-3
  
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nature.com/articles/s41551-023-01023-3
Feb 2023
onlinelibrary.wiley.com onlinelibrary.wiley.com

CTLA-4 inhibition facilitates follicular T and B cell interaction and the production of tumor-specific antibodies

1
1. scibot 03 Feb 2023
  
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  RRID:CVCL_7254
  
  DOI: 10.1002/ijc.34438
  
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onlinelibrary.wiley.com/doi/10.1002/ijc.34438
Jan 2023
aacrjournals.org aacrjournals.org

Enhancing PD-L1 Degradation by ITCH during MAPK Inhibitor Therapy Suppresses Acquired Resistance

1
1. scibot 11 Jan 2023
  
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  RRID:CVCL_7254
  
  DOI: 10.1158/2159-8290.CD-21-1463
  
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aacrjournals.org/cancerdiscovery/article/12/8/1942/707227/Enhancing-PD-L1-Degradation-by-ITCH-during-MAPK
onlinelibrary.wiley.com onlinelibrary.wiley.com

Immunotherapies targeting neoantigens are effective in PD-1 blockade-resistant tumors

1
1. scibot 10 Jan 2023
  
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  RRID:CVCL_7254
  
  DOI: 10.1002/ijc.34382
  
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onlinelibrary.wiley.com/doi/10.1002/ijc.34382
Oct 2022
aacrjournals.org aacrjournals.org

Sirpiglenastat (DRP-104) Induces Anti-tumor Efficacy Through Direct, Broad Antagonism of Glutamine Metabolism and Stimulation of the Innate & Adaptive Immune Systems

1
1. scibot 27 Oct 2022
  
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  RRID:CVCL_7254
  
  DOI: 10.1158/1535-7163.MCT-22-0282
  
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aacrjournals.org/mct/article/21/10/1561/709527/Sirpiglenastat-DRP-104-Induces-Antitumor-Efficacy
Aug 2022
www.sciencedirect.com www.sciencedirect.com

Tumor-infiltrated activated B cells suppress liver metastasis of colorectal cancers

1
1. scibot 31 Aug 2022
  
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  CVCL_7254
  
  DOI: 10.1016/j.celrep.2022.111295
  
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sciencedirect.com/science/article/pii/S2211124722011159
onlinelibrary.wiley.com onlinelibrary.wiley.com

Nigakinone alleviates DSS-induced experimental colitis via regulating bile acid profile and FXR/NLRP3 signaling pathways

1
1. scibot 24 Aug 2022
  
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  RRID: CVCL_7254
  
  DOI: 10.1002/ptr.7588
  
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onlinelibrary.wiley.com/doi/10.1002/ptr.7588
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A multi-omic single cell sequencing approach to develop a CD8 T cell specific gene signature for anti-PD1 response in solid tumors

1
1. scibot 10 Aug 2022
  
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  RRID: CVCL_7254
  
  DOI: 10.1002/ijc.34218
  
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onlinelibrary.wiley.com/doi/10.1002/ijc.34218
Feb 2022
www.nature.com www.nature.com

Efficient recovery of potent tumour-infiltrating lymphocytes through quantitative immunomagnetic cell sorting

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1. scibot 05 Feb 2022
  
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  RRID:CVCL_7254
  
  DOI: 10.1038/s41551-021-00820-y
  
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nature.com/articles/s41551-021-00820-y
Jan 2022
onlinelibrary.wiley.com onlinelibrary.wiley.com

SKI-G-801, an AXL kinase inhibitor, blocks metastasis through inducing anti-tumor immune responses and potentiates anti-PD-1 therapy in mouse cancer models

1
1. scibot 04 Jan 2022
  
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  CVCL_7254
  
  DOI: 10.1002/cti2.1364
  
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onlinelibrary.wiley.com/doi/10.1002/cti2.1364
Oct 2021
www.nature.com www.nature.com

XBP1 regulates the protumoral function of tumor-associated macrophages in human colorectal cancer

1
1. scibot 23 Oct 2021
  
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  CVCL_7254
  
  DOI: 10.1038/s41392-021-00761-7
  
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nature.com/articles/s41392-021-00761-7
Sep 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Inhibition of BCL9 Modulates the Cellular Landscape of Tumor-Associated Macrophages in the Tumor Immune Microenvironment of Colorectal Cancer

1
1. scibot 28 Sep 2021
  
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  RRID:CVCL_7254
  
  DOI: 10.3389/fphar.2021.713331
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8461101/
onlinelibrary.wiley.com onlinelibrary.wiley.com

Extracellular acidity in tumor tissue upregulates PD-L1 expression on tumor cells via proton-sensing G protein-coupled receptors

1
1. scibot 23 Sep 2021
  
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  RRID:CVCL_7254
  
  DOI: 10.1002/ijc.33786
  
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onlinelibrary.wiley.com/doi/10.1002/ijc.33786
May 2021
onlinelibrary.wiley.com onlinelibrary.wiley.com

Suppression of β-catenin signaling in colon carcinoma cells by a bacterial protein

1
1. scibot 20 May 2021
  
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  RRID:CVCL_7254
  
  DOI: 10.1002/ijc.33562
  
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onlinelibrary.wiley.com/doi/10.1002/ijc.33562
www.sciencedirect.com www.sciencedirect.com

An Oncogenic Alteration Creates a Microenvironment that Promotes Tumor Progression by Conferring a Metabolic Advantage to Regulatory T Cells

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1. scibot 06 May 2021
  
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  RRID:CVCL_7254
  
  DOI: 10.1016/j.immuni.2020.06.016
  
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sciencedirect.com/science/article/pii/S1074761320302715
Mar 2021
onlinelibrary.wiley.com onlinelibrary.wiley.com

Nanofitins targeting heat shock protein 110: an innovative immunotherapeutic modality in cancer.

1
1. scibot 08 Mar 2021
  
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  RRID:CVCL_7254
  
  DOI: 10.1002/ijc.33485
  
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onlinelibrary.wiley.com/doi/full/10.1002/ijc.33485
Feb 2021
www.sciencedirect.com www.sciencedirect.com

Cetuximab enhances the anti-tumor function of macrophages in an IL-6 dependent manner

1
1. scibot 27 Feb 2021
  
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  CVCL_7254
  
  DOI: 10.1016/j.lfs.2020.118953
  
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sciencedirect.com/science/article/pii/S0024320520317136
Sep 2020
academic.oup.com academic.oup.com

Newly emerged immunogenic neoantigens in established tumors enable hosts to regain immunosurveillance in a T cell-dependent manner

1
1. scibot 08 Sep 2020
  
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  RRID:CVCL_7254
  
  DOI: 10.1093/intimm/dxaa049
  
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academic.oup.com/intimm/intimm/advance-article-abstract/doi/10.1093/intimm/dxaa049/5878926

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