Hypothesis

163 Matching Annotations

Aug 2025
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Targeting ECM-producing cells with CAR-T therapy alleviates fibrosis in chronic kidney disease

1
1. scibot 26 Aug 2025
  
  in Public
  
  CVCL_7256
  
  DOI: 10.1016/j.stem.2025.07.014
  
  Resource: (ATCC Cat# CRL-2638, RRID:CVCL_7256)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_7256
  
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  RRID:CVCL_7256
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sciencedirect.com/science/article/pii/S1934590925002711
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Tumor-resident probiotic Clostridium butyricum improves aPD-1 efficacy in colorectal cancer models by inhibiting IL-6-mediated immunosuppression

1
1. scibot 08 Aug 2025
  
  in Public
  
  ATCCCRL-2638
  
  DOI: 10.1016/j.ccell.2025.07.012
  
  Resource: (ATCC Cat# CRL-2638, RRID:CVCL_7256)
  
  Curator: @areedewitt04
  
  SciCrunch record: RRID:CVCL_7256
  
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  RRID:CVCL_7256
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sciencedirect.com/science/article/pii/S1535610825003186
Jul 2025
www.sciencedirect.com www.sciencedirect.com

Alistipes finegoldii augments the efficacy of immunotherapy against solid tumors

1
1. scibot 25 Jul 2025
  
  in Public
  
  RRID:CVCL_7256
  
  DOI: 10.1016/j.ccell.2025.07.002
  
  Resource: (ATCC Cat# CRL-2638, RRID:CVCL_7256)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_7256
  
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  RRID:CVCL_7256
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sciencedirect.com/science/article/pii/S1535610825002739
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Glucose restriction shapes pre-metastatic innate immune landscapes in the lung through exosomal TRAIL

1
1. scibot 16 Jul 2025
  
  in Public
  
  ATCC®CRL-2638
  
  DOI: 10.1016/j.cell.2025.06.027
  
  Resource: (ATCC Cat# CRL-2638, RRID:CVCL_7256)
  
  Curator: @areedewitt04
  
  SciCrunch record: RRID:CVCL_7256
  
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  RRID:CVCL_7256
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sciencedirect.com/science/article/pii/S0092867425007287
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Covalent inhibition of ACSL4 alleviates ferroptosis-induced acute liver injury

1
1. scibot 09 Jul 2025
  
  in Public
  
  ATCCCat#CRL-2638
  
  DOI: 10.1016/j.chembiol.2025.06.004
  
  Resource: (ATCC Cat# CRL-2638, RRID:CVCL_7256)
  
  Curator: @areedewitt04
  
  SciCrunch record: RRID:CVCL_7256
  
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  RRID:CVCL_7256
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sciencedirect.com/science/article/pii/S2451945625001990
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Riluzole Enhancing anti-PD-1 Efficacy by Activating cGAS/STING Signaling in Colorectal Cancer

1
1. scibot 04 Jul 2025
  
  in Public
  
  CVCL_7256
  
  DOI: 10.1158/1535-7163.MCT-24-0289
  
  Resource: (ATCC Cat# CRL-2638, RRID:CVCL_7256)
  
  Curator: @sonofthor
  
  SciCrunch record: RRID:CVCL_7256
  
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  RRID:CVCL_7256
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pmc.ncbi.nlm.nih.gov/articles/PMC11695182/
Jun 2025
www.sciencedirect.com www.sciencedirect.com

Plinabulin following radiation enhances dendritic cell maturation and checkpoint inhibitor retreatment of relapsed/refractory cancers

1
1. scibot 28 Jun 2025
  
  in Public
  
  ATCCCRL-2638
  
  DOI: 10.1016/j.medj.2025.100752
  
  Resource: (ATCC Cat# CRL-2638, RRID:CVCL_7256)
  
  Curator: @areedewitt04
  
  SciCrunch record: RRID:CVCL_7256
  
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  RRID:CVCL_7256
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sciencedirect.com/science/article/pii/S2666634025001795
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A CXCR4 partial agonist improves immunotherapy by targeting immunosuppressive neutrophils and cancer-driven granulopoiesis

1
1. scibot 28 Jun 2025
  
  in Public
  
  ATCCCRL-2638
  
  DOI: 10.1016/j.ccell.2025.06.006
  
  Resource: (ATCC Cat# CRL-2638, RRID:CVCL_7256)
  
  Curator: @areedewitt04
  
  SciCrunch record: RRID:CVCL_7256
  
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  RRID:CVCL_7256
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sciencedirect.com/science/article/pii/S1535610825002569
www.tandfonline.com www.tandfonline.com

Cancer cells accelerate exhaustion of persistently activated mouse CD4+ T cells

1
1. scibot 22 Jun 2025
  
  in Public
  
  RRID: CVCL_7256
  
  DOI: 10.1080/2162402X.2025.2521392
  
  Resource: (ATCC Cat# CRL-2638, RRID:CVCL_7256)
  
  Curator: @sjvitug
  
  SciCrunch record: RRID:CVCL_7256
  
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  RRID:CVCL_7256
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tandfonline.com/doi/full/10.1080/2162402X.2025.2521392
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Induction of a mismatch repair deficient genotype by tailored chemical mutagenesis in experimental models of cancer

1
1. scibot 13 Jun 2025
  
  in Public
  
  ATCCCRL2638
  
  DOI: 10.1016/j.ccell.2025.05.010
  
  Resource: (ATCC Cat# CRL-2638, RRID:CVCL_7256)
  
  Curator: @areedewitt04
  
  SciCrunch record: RRID:CVCL_7256
  
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  RRID:CVCL_7256
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sciencedirect.com/science/article/pii/S1535610825002193
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Cisplatin and temozolomide combinatorial treatment triggers hypermutability and immune surveillance in experimental cancer models

1
1. scibot 13 Jun 2025
  
  in Public
  
  RRID:CVCL_7256
  
  DOI: 10.1016/j.ccell.2025.05.014
  
  Resource: (ATCC Cat# CRL-2638, RRID:CVCL_7256)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_7256
  
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  RRID:CVCL_7256
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RRID:CVCL_7256

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sciencedirect.com/science/article/pii/S1535610825002235
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Distinct TAM subset with cross-dressing capability determines the bifurcation of tumor immunity

1
1. scibot 11 Jun 2025
  
  in Public
  
  ATCCCRL-2638
  
  DOI: 10.1016/j.celrep.2025.115800
  
  Resource: (ATCC Cat# CRL-2638, RRID:CVCL_7256)
  
  Curator: @areedewitt04
  
  SciCrunch record: RRID:CVCL_7256
  
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  RRID:CVCL_7256
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RRID:CVCL_7256

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sciencedirect.com/science/article/pii/S2211124725005716
May 2025
www.sciencedirect.com www.sciencedirect.com

Serotonin transporter inhibits antitumor immunity through regulating the intratumoral serotonin axis

1
1. scibot 22 May 2025
  
  in Public
  
  ATCCCAT# CRL-2638
  
  DOI: 10.1016/j.cell.2025.04.032
  
  Resource: (ATCC Cat# CRL-2638, RRID:CVCL_7256)
  
  Curator: @areedewitt04
  
  SciCrunch record: RRID:CVCL_7256
  
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  RRID:CVCL_7256
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RRID:CVCL_7256

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scibot

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sciencedirect.com/science/article/pii/S0092867425005021
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

S-adenosylmethionine metabolism shapes CD8+ T cell functions in colorectal cancer

1
1. scibot 22 May 2025
  
  in Public
  
  RRID:CVCL_7256
  
  DOI: 10.1186/s40170-025-00394-2
  
  Resource: (ATCC Cat# CRL-2638, RRID:CVCL_7256)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_7256
  
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  RRID:CVCL_7256
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RRID:CVCL_7256

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URL

pmc.ncbi.nlm.nih.gov/articles/PMC12090577/
www.sciencedirect.com www.sciencedirect.com

Enhanced delivery of camptothecin to colorectal carcinoma using a tumor-penetrating peptide targeting p32

1
1. scibot 20 May 2025
  
  in Public
  
  ATCC, CRL-2638
  
  DOI: 10.1016/j.actbio.2025.05.036
  
  Resource: (ATCC Cat# CRL-2638, RRID:CVCL_7256)
  
  Curator: @areedewitt04
  
  SciCrunch record: RRID:CVCL_7256
  
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  RRID:CVCL_7256
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RRID:CVCL_7256

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URL

sciencedirect.com/science/article/pii/S1742706125003617
link.springer.com link.springer.com

SPP1 + macrophages cause exhaustion of tumor-specific T cells in liver metastases

1
1. scibot 19 May 2025
  
  in Public
  
  RRID:CVCL_7256
  
  DOI: 10.1038/s41467-025-59529-0
  
  Resource: (ATCC Cat# CRL-2638, RRID:CVCL_7256)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_7256
  
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  RRID:CVCL_7256
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RRID:CVCL_7256

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URL

link.springer.com/article/10.1038/s41467-025-59529-0
www.sciencedirect.com www.sciencedirect.com

Glycosylation-driven programs coordinate immunoregulatory and pro-angiogenic functions of myeloid-derived suppressor cells

1
1. scibot 18 May 2025
  
  in Public
  
  RRID:CVCL_7256
  
  DOI: 10.1016/j.immuni.2025.04.027
  
  Resource: (ATCC Cat# CRL-2638, RRID:CVCL_7256)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_7256
  
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  RRID:CVCL_7256
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RRID:CVCL_7256

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scibot

URL

sciencedirect.com/science/article/pii/S1074761325001906
Apr 2025
www.sciencedirect.com www.sciencedirect.com

The low-dose CHK1 inhibitor prexasertib triggers VDAC1 dephosphorylation to activate mtDNA-STING signaling and synergize immunotherapy

1
1. scibot 19 Apr 2025
  
  in Public
  
  ATCCCRL-2638
  
  DOI: 10.1016/j.celrep.2025.115605
  
  Resource: (ATCC Cat# CRL-2638, RRID:CVCL_7256)
  
  Curator: @areedewitt04
  
  SciCrunch record: RRID:CVCL_7256
  
  What is this?
  
  RRID:CVCL_7256
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RRID:CVCL_7256

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scibot

URL

sciencedirect.com/science/article/pii/S2211124725003766
link.springer.com link.springer.com

Colon cancer exosome-associated HSP90B1 initiates pre-metastatic niche formation in the liver by polarizing M1 macrophage into M2 phenotype

1
1. scibot 17 Apr 2025
  
  in Public
  
  RRID:CVCL_7256
  
  DOI: 10.1186/s13062-025-00623-0
  
  Resource: (ATCC Cat# CRL-2638, RRID:CVCL_7256)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_7256
  
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  RRID:CVCL_7256
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RRID:CVCL_7256

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scibot

URL

link.springer.com/article/10.1186/s13062-025-00623-0
www.sciencedirect.com www.sciencedirect.com

N-(5-(2-morpholino-4-oxo-3,4-dihydroquinazolin-8-yl)pyridin-2-yl)acylamides as novel multi-PI3K/DNA-PK/P-gp inhibitors for efficient chemosensitization and MDR alleviation

1
1. scibot 17 Apr 2025
  
  in Public
  
  RRID:CVCL_7256
  
  DOI: 10.1016/j.ejmech.2025.117641
  
  Resource: (ATCC Cat# CRL-2638, RRID:CVCL_7256)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_7256
  
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  RRID:CVCL_7256
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RRID:CVCL_7256

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URL

sciencedirect.com/science/article/pii/S0223523425004064
www.sciencedirect.com www.sciencedirect.com

Pyruvate kinase M2 activation reprograms mitochondria in CD8 T cells, enhancing effector functions and efficacy of anti-PD1 therapy

1
1. scibot 08 Apr 2025
  
  in Public
  
  RRID:CVCL_7256
  
  DOI: 10.1016/j.cmet.2025.03.003
  
  Resource: (ATCC Cat# CRL-2638, RRID:CVCL_7256)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_7256
  
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  RRID:CVCL_7256
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RRID:CVCL_7256

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scibot

URL

sciencedirect.com/science/article/pii/S1550413125001068
www.sciencedirect.com www.sciencedirect.com

PAR2 deficiency impairs antitumor immunity and attenuates anti-PD1 efficacy in colorectal cancer

1
1. scibot 03 Apr 2025
  
  in Public
  
  CRL-2638
  
  DOI: 10.1016/j.phrs.2025.107721
  
  Resource: (ATCC Cat# CRL-2638, RRID:CVCL_7256)
  
  Curator: @areedewitt04
  
  SciCrunch record: RRID:CVCL_7256
  
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  RRID:CVCL_7256
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scibot

URL

sciencedirect.com/science/article/pii/S104366182500146X
www.sciencedirect.com www.sciencedirect.com

Soluble CTLA-4 regulates immune homeostasis and promotes resolution of inflammation by suppressing type 1 but allowing type 2 immunity

1
1. scibot 01 Apr 2025
  
  in Public
  
  ATCCCat#CRL-2638
  
  DOI: 10.1016/j.immuni.2025.03.004
  
  Resource: (ATCC Cat# CRL-2638, RRID:CVCL_7256)
  
  Curator: @areedewitt04
  
  SciCrunch record: RRID:CVCL_7256
  
  What is this?
  
  RRID:CVCL_7256
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RRID:CVCL_7256

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URL

sciencedirect.com/science/article/pii/S1074761325001232
Mar 2025
52.53.155.43 52.53.155.43

PDF-html.html

1
1. scibot 26 Mar 2025
  
  in Public
  
  RRID:CVCL_7256
  
  DOI: 10.1101/2025.03.14.642985
  
  Resource: (ATCC Cat# CRL-2638, RRID:CVCL_7256)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_7256
  
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  RRID:CVCL_7256
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RRID:CVCL_7256

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scibot

URL

52.53.155.43/59f01b99c7b267c6741834ba4d27823473c7d4e7/PDF-html.html
52.53.155.43 52.53.155.43

PDF-html.html

1
1. scibot 24 Mar 2025
  
  in Public
  
  CRL - 2638
  
  DOI: 10.1158/1535-7163.mct-24-0597
  
  Resource: (ATCC Cat# CRL-2638, RRID:CVCL_7256)
  
  Curator: @sjvitug
  
  SciCrunch record: RRID:CVCL_7256
  
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  RRID:CVCL_7256
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RRID:CVCL_7256

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scibot

URL

52.53.155.43/8ab77eebe2f713b38b19e9b762e6b4fd50f71e05/PDF-html.html
www.cell.com www.cell.com

Lactylation orchestrates ubiquitin-independent degradation of cGAS and promotes tumor growth

1
1. scibot 20 Mar 2025
  
  in Public
  
  RRID:CVCL_7256
  
  DOI: 10.1016/j.celrep.2025.115441
  
  Resource: (ATCC Cat# CRL-2638, RRID:CVCL_7256)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_7256
  
  What is this?
  
  RRID:CVCL_7256
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RRID:CVCL_7256

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URL

cell.com/cell-reports/fulltext/S2211-1247(25)00212-8
Feb 2025
www.sciencedirect.com www.sciencedirect.com

Bidirectional activation of stem-like programs between metastatic cancer and alveolar type 2 cells within the niche

1
1. scibot 27 Feb 2025
  
  in Public
  
  ATCCCat# CRL-2638
  
  DOI: 10.1016/j.devcel.2024.05.020
  
  Resource: (ATCC Cat# CRL-2638, RRID:CVCL_7256)
  
  Curator: @areedewitt04
  
  SciCrunch record: RRID:CVCL_7256
  
  What is this?
  
  RRID:CVCL_7256
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URL

sciencedirect.com/science/article/pii/S1534580724003381
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Short-chain fatty acid metabolites propionate and butyrate are unique epigenetic regulatory elements linking diet, metabolism and gene expression

7
1. scibot 07 Feb 2025
  
  in Public
  
  CRL-2638
  
  DOI: 10.1038/s42255-024-01191-9
  
  Resource: (ATCC Cat# CRL-2638, RRID:CVCL_7256)
  
  Curator: @dhovakimyan1
  
  SciCrunch record: RRID:CVCL_7256
  
  What is this?
  
  RRID:CVCL_7256
2. scibot 06 Feb 2025
  
  in Public
  
  CRL-2638
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:CVCL_7256
3. scibot 05 Feb 2025
  
  in Public
  
  CRL-2638
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:CVCL_7256
4. scibot 04 Feb 2025
  
  in Public
  
  CRL-2638
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:CVCL_7256
5. scibot 03 Feb 2025
  
  in Public
  
  CRL-2638
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:CVCL_7256
6. scibot 02 Feb 2025
  
  in Public
  
  CRL-2638
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:CVCL_7256
7. scibot 01 Feb 2025
  
  in Public
  
  CRL-2638
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:CVCL_7256
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URL

pmc.ncbi.nlm.nih.gov/articles/PMC11774759/
Jan 2025
aacrjournals.org aacrjournals.org

High Expression of MHC Class I Overcomes Cancer Immunotherapy Resistance Due to IFNγ Signaling Pathway Defects

1
1. scibot 31 Jan 2025
  
  in Public
  
  CRL-2638
  
  DOI: 10.1158/2326-6066.CIR-22-0815
  
  Resource: (ATCC Cat# CRL-2638, RRID:CVCL_7256)
  
  Curator: @areedewitt04
  
  SciCrunch record: RRID:CVCL_7256
  
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  RRID:CVCL_7256
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URL

aacrjournals.org/cancerimmunolres/article/11/7/895/727496/High-Expression-of-MHC-Class-I-Overcomes-Cancer
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Short-chain fatty acid metabolites propionate and butyrate are unique epigenetic regulatory elements linking diet, metabolism and gene expression

1
1. scibot 31 Jan 2025
  
  in Public
  
  CRL-2638
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:CVCL_7256
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RRID:CVCL_7256

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scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC11774759/
www.sciencedirect.com www.sciencedirect.com

ISCOM-type matrix from beta-escin and glycyrrhizin saponins

1
1. scibot 16 Jan 2025
  
  in Public
  
  RRID:CVCL_7256
  
  DOI: 10.1016/j.heliyon.2025.e41935
  
  Resource: (ATCC Cat# CRL-2638, RRID:CVCL_7256)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_7256
  
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  RRID:CVCL_7256
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sciencedirect.com/science/article/pii/S2405844025003159
www.sciencedirect.com www.sciencedirect.com

Phenotypic plasticity and increased infiltration of peripheral blood-derived TREM1+ mono-macrophages following radiotherapy in rectal cancer

1
1. scibot 14 Jan 2025
  
  in Public
  
  American Type Culture CollectionCRL-2638
  
  DOI: 10.1016/j.xcrm.2024.101887
  
  Resource: (ATCC Cat# CRL-2638, RRID:CVCL_7256)
  
  Curator: @areedewitt04
  
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Inhibiting intracellular CD28 in cancer cells enhances antitumor immunity and overcomes anti-PD-1 resistance via targeting PD-L1

1
1. scibot 09 Jan 2025
  
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  ATCCCat# CRL-2638
  
  DOI: 10.1016/j.ccell.2024.11.008
  
  Resource: (ATCC Cat# CRL-2638, RRID:CVCL_7256)
  
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Targeting P4HA1 promotes CD8+ T cell progenitor expansion toward immune memory and systemic anti-tumor immunity

1
1. scibot 29 Dec 2024
  
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  CRL-2638
  
  DOI: 10.1016/s0195-668x(03)00476-7
  
  Resource: (ATCC Cat# CRL-2638, RRID:CVCL_7256)
  
  Curator: @sjvitug
  
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cell.com/cancer-cell/abstract/S1535-6108(24)00476-8
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IL-17A/CEBPβ/OPN/LYVE-1 axis inhibits anti-tumor immunity by promoting tumor-associated tissue-resident macrophages

1
1. scibot 12 Dec 2024
  
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  ATCCCat# CRL-2638
  
  DOI: 10.1016/j.celrep.2024.115039
  
  Resource: (ATCC Cat# CRL-2638, RRID:CVCL_7256)
  
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52.53.155.43 52.53.155.43

Enhancing Immune Response and Survival in Hepatocellular Carcinoma with Novel Oncolytic Jurona Virus and Immune Checkpoint Blockade

1
1. scibot 06 Dec 2024
  
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  RRID:CVCL_7256
  
  DOI: 10.1016/j.omton.2024.200913
  
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52.53.155.43/b17d322494c44a28e0d2e52b4d7ea9e056092d31/Enhancing Immune Response and Survival in Hepatocellular Carcinoma with Novel Oncolytic Jurona Virus and Immune Checkpoint Blockade-html.html
Nov 2024
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Targeting the aminopeptidase ERAP enhances antitumor immunity by disrupting the NKG2A-HLA-E inhibitory checkpoint

1
1. scibot 24 Nov 2024
  
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  RRID:CVCL_7256
  
  DOI: 10.1016/j.immuni.2024.10.013
  
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Thymosin α1 reverses oncolytic adenovirus-induced M2 polarization of macrophages to improve antitumor immunity and therapeutic efficacy

1
1. scibot 07 Nov 2024
  
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  CRL-2638
  
  DOI: 10.1016/j.xcrm.2024.101751
  
  Resource: (ATCC Cat# CRL-2638, RRID:CVCL_7256)
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11513825/
Sep 2024
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CXCR4 orchestrates the TOX-programmed exhausted phenotype of CD8+ T cells via JAK2/STAT3 pathway

1
1. scibot 26 Sep 2024
  
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  RRID:CVCL_7256
  
  DOI: 10.1016/j.xgen.2024.100659
  
  Resource: (ATCC Cat# CRL-2638, RRID:CVCL_7256)
  
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Fusobacterium nucleatum facilitates anti-PD-1 therapy in microsatellite stable colorectal cancer

1
1. scibot 25 Sep 2024
  
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  CRL-2638
  
  DOI: 10.1016/j.ccell.2024.08.019
  
  Resource: (ATCC Cat# CRL-2638, RRID:CVCL_7256)
  
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Tumour-associated mesenchymal stromal cells modulate macrophage phagocytosis in stromal-rich colorectal cancer via PD-1 signalling.

1
1. scibot 25 Sep 2024
  
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  RRID:CVCL_7256
  
  DOI: 10.1016/j.isci.2024.110701
  
  Resource: (ATCC Cat# CRL-2638, RRID:CVCL_7256)
  
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Opposing Functions of Interferon Coordinate Adaptive and Innate Immune Responses to Cancer Immune Checkpoint Blockade

1
1. scibot 25 Sep 2024
  
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  RRID:CVCL_7254
  
  DOI: 10.1016/j.cell.2019.07.019
  
  Resource: (KCLB Cat# 80009, RRID:CVCL_7254)
  
  Curator: @ethanbadger
  
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Small-molecule GSDMD agonism in tumors stimulates antitumor immunity without toxicity

1
1. scibot 10 Sep 2024
  
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  CRL-2638
  
  DOI: 10.1016/j.cell.2024.08.007
  
  Resource: (ATCC Cat# CRL-2638, RRID:CVCL_7256)
  
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Aug 2024
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Endocytosis Inhibition in Humans to Improve Responses to ADCC-Mediating Antibodies

1
1. scibot 22 Aug 2024
  
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  RRID:CVCL_7256
  
  DOI: 10.1016/j.cell.2020.02.019
  
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cell.com/cell/fulltext/S0092-8674(20)30163-X
Jul 2024
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Original research: Second-generation checkpoint inhibitors and Treg depletion synergize with a mouse cancer vaccine in accordance with tumor microenvironment characterization

1
1. scibot 04 Jul 2024
  
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  RRID:CVCL_7256
  
  DOI: 10.1136/jitc-2024-008970
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11218019/
Jun 2024
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Moderate-intensity aerobic exercise training improves CD8+ tumor-infiltrating lymphocytes effector function by reducing mitochondrial loss.

1
1. scibot 30 Jun 2024
  
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  RRID:CVCL_7256
  
  DOI: 10.1016/j.isci.2024.110121
  
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cell.com/iscience/abstract/S2589-0042(24)01346-4
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Epigenetic Priming by Hypomethylation Enhances the Immunogenic Potential of Tolinapant in T-cell Lymphoma

1
1. scibot 09 Jun 2024
  
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  RRID:CVCL_7256
  
  DOI: 10.1158/2767-9764.CRC-23-0415
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11155518/
May 2024
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MDM2/MDMX inhibition by Sulanemadlin synergizes with anti-Programmed Death 1 immunotherapy in wild-type p53 tumors

1
1. scibot 25 May 2024
  
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  CRL-2638
  
  DOI: 10.1016/j.isci.2024.109862
  
  Resource: (ATCC Cat# CRL-2638, RRID:CVCL_7256)
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11112618/
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Spatiotemporal quantification of HER2-targeting antibody-drug conjugate bystander activity and enhancement of solid tumor penetration

1
1. scibot 23 May 2024
  
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  RRID:CVCL_7256
  
  DOI: 10.1158/1078-0432.CCR-23-1725
  
  Resource: (ATCC Cat# CRL-2638, RRID:CVCL_7256)
  
  Curator: @abever99
  
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  DOI:10.1158/1078-0432.CCR-23-1725 RRID:CVCL_7256
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aacrjournals.org/clincancerres/article/30/5/984/734305/Spatiotemporal-Quantification-of-HER2-targeting
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TREX1 inactivation unleashes cancer cell STING-interferon signaling and promotes anti-tumor immunity

2
1. scibot 23 May 2024
  
  in Public
  
  RRID:CVCL_7256
  
  DOI: 10.1158/2159-8290.CD-23-0700
  
  Resource: (ATCC Cat# CRL-2638, RRID:CVCL_7256)
  
  Curator: @scibot
  
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  RRID:CVCL_7256
2. scibot 23 May 2024
  
  in Public
  
  RRID:CVCL_7256
  
  DOI: 10.1158/2159-8290.CD-23-0700
  
  Resource: (ATCC Cat# CRL-2638, RRID:CVCL_7256)
  
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aacrjournals.org/cancerdiscovery/article/14/5/752/745044/TREX1-Inactivation-Unleashes-Cancer-Cell-STING
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ARID1A suppresses R-loop-mediated STING-type I interferon pathway activation of anti-tumor immunity

1
1. scibot 21 May 2024
  
  in Public
  
  CRL-2638
  
  DOI: 10.1016/j.cell.2024.04.025
  
  Resource: (ATCC Cat# CRL-2638, RRID:CVCL_7256)
  
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sciencedirect.com/science/article/pii/S0092867424004513
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HuR promotes triglyceride synthesis and intestinal fat absorption

1
1. scibot 16 May 2024
  
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  CRL-2638
  
  DOI: 10.1016/j.celrep.2024.114238
  
  Resource: (ATCC Cat# CRL-2638, RRID:CVCL_7256)
  
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sciencedirect.com/science/article/pii/S2211124724005667
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IL-7-primed bystander CD8 tumor-infiltrating lymphocytes optimize the antitumor efficacy of T cell engager immunotherapy

1
1. scibot 14 May 2024
  
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  CRL-2638
  
  DOI: 10.1016/j.xcrm.2024.101567
  
  Resource: (ATCC Cat# CRL-2638, RRID:CVCL_7256)
  
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RGD Targeted Magnetic Ferrite Nanoparticles Enhance Antitumor Immunotherapeutic Efficacy by Activating STING Signaling Pathway

1
1. scibot 01 May 2024
  
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  Cat# CRL-2638
  
  DOI: 10.1016/j.isci.2024.109062
  
  Resource: (ATCC Cat# CRL-2638, RRID:CVCL_7256)
  
  Curator: @evieth
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11039334/
Apr 2024
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CRISPR-Cas9 screening identifies INTS3 as an anti-apoptotic RNA-binding protein and therapeutic target for colorectal cancer

1
1. scibot 28 Apr 2024
  
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  RRID:CVCL_7256
  
  DOI: 10.1016/j.isci.2024.109676
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11043890/
www.embopress.org www.embopress.org

The regulatory relationship between NAMPT and PD-L1 in cancer and identification of a dual-targeting inhibitor

2
1. scibot 25 Apr 2024
  
  in Public
  
  CRL-2638
  
  DOI: 10.1038/s44321-024-00051-z
  
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  Curator: @abever99
  
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  RRID:CVCL_7256
2. scibot 20 Apr 2024
  
  in Public
  
  ATCC CRL-2638
  
  DOI: 10.1038/s44321-024-00051-z
  
  Resource: (ATCC Cat# CRL-2638, RRID:CVCL_7256)
  
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embopress.org/doi/full/10.1038/s44321-024-00051-z
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IGSF8 is an innate immune checkpoint and cancer immunotherapy target

1
1. scibot 24 Apr 2024
  
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  Cat# CRL-2638
  
  DOI: 10.1016/j.cell.2024.03.039
  
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  Curator: @abever99
  
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Cancer SLC6A6-mediated taurine uptake transactivates immune checkpoint genes and induces exhaustion in CD8+ T cells

1
1. scibot 02 Apr 2024
  
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  CRL-2638
  
  DOI: 10.1016/j.cell.2024.03.011
  
  Resource: (ATCC Cat# CRL-2638, RRID:CVCL_7256)
  
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sciencedirect.com/science/article/pii/S0092867424003039
Mar 2024
febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com

Combining VPS34 inhibitors with STING agonists enhances type I interferon signaling and anti-tumor efficacy

1
1. scibot 28 Mar 2024
  
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  RRID:CVCL_7256
  
  DOI: 10.1002/1878-0261.13619
  
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febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.13619
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Long-lasting mRNA-encoded interleukin-2 restores CD8+ T cell neoantigen immunity in MHC class I-deficient cancers

1
1. scibot 15 Mar 2024
  
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  ATCCCat# CRL-2638
  
  DOI: 10.1016/j.ccell.2024.02.013
  
  Resource: (ATCC Cat# CRL-2638, RRID:CVCL_7256)
  
  Curator: @abever99
  
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52.53.155.43 52.53.155.43

1-s2.0-S2589004224002839-main-html.html

1
1. scibot 06 Mar 2024
  
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  CRL-2638
  
  DOI: 10.3892/ijo.2023.5518
  
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52.53.155.43/e4b4251b496f91f14f0400600f97646c0efe1fb3/1-s2.0-S2589004224002839-main-html.html
Feb 2024
52.53.155.43 52.53.155.43

delete 2-html.html

2
1. scibot 29 Feb 2024
  
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  RRID:CVCL_7256
  
  DOI: 10.1158/1078-0432.ccr-23-1725
  
  Resource: (ATCC Cat# CRL-2638, RRID:CVCL_7256)
  
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  RRID:CVCL_7256
2. scibot 29 Feb 2024
  
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  RRID:CVCL_7256
  
  DOI: 10.1158/1078-0432.ccr-23-1725
  
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52.53.155.43/a4c93586535c0b08f8ee7ba1c2f0ff163de1bcc6/delete 2-html.html
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Novel Lipid Nanoparticles Stable and Efficient for mRNA Transfection to Antigen-Presenting Cells

1
1. scibot 02 Feb 2024
  
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  CRL-2638
  
  DOI: 10.3390/ijms25031388
  
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mdpi.com/1422-0067/25/3/1388
Jan 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

MIIP downregulation drives colorectal cancer progression through inducing peri-cancerous adipose tissue browning

1
1. scibot 23 Jan 2024
  
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  RRID:CVCL_7256
  
  DOI: 10.1186/s13578-023-01179-0
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10800076/
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Clinical and molecular features of acquired resistance to immunotherapy in non-small cell lung cancer

1
1. scibot 12 Jan 2024
  
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  RRID:CVCL_7256
  
  DOI: 10.1016/j.ccell.2023.12.013
  
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sciencedirect.com/science/article/pii/S1535610823004415
Dec 2023
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Molecular cartography uncovers evolutionary and microenvironmental dynamics in sporadic colorectal tumors

1
1. scibot 17 Dec 2023
  
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  RRID:CVCL_7256
  
  DOI: 10.1016/j.cell.2023.11.006
  
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sciencedirect.com/science/article/pii/S0092867423012229
Nov 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

SIX4 Controls Anti-PD-1 Efficacy by Regulating STING Expression

1
1. scibot 30 Nov 2023
  
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  RRID:CVCL_7256
  
  DOI: 10.1158/2767-9764.CRC-23-0265
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10680432/
Oct 2023
www.mdpi.com www.mdpi.com

Inflammation-Related Immune-Modulatory SLURP1 Prevents the Proliferation of Human Colon Cancer Cells, and Its Delivery by Salmonella Demonstrates Cross-Species Efficacy against Murine Colon Cancer

1
1. scibot 22 Oct 2023
  
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  RRID:CVCL_7256
  
  DOI: 10.3390/pharmaceutics15102462
  
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mdpi.com/1999-4923/15/10/2462
faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com

In vivo transfection of cytokine genes into tumor cells using a synthetic vehicle promotes antitumor immune responses in a visceral tumor model

1
1. scibot 20 Oct 2023
  
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  RRID:CVCL_7256
  
  DOI: 10.1096/fj.202202036R
  
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faseb.onlinelibrary.wiley.com/doi/10.1096/fj.202202036R
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The CX3CL1-CX3CR1 chemokine axis can contribute to tumor immune evasion and blockade with a novel CX3CR1 monoclonal antibody enhances response to anti-PD-1 immunotherapy

1
1. scibot 06 Oct 2023
  
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  CVCL_7256
  
  DOI: 10.3389/fimmu.2023.1237715
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10524267/
Sep 2023
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Zebrafish functional xenograft vasculature platform identifies PF-502 as a durable vasculature normalization drug

1
1. scibot 08 Sep 2023
  
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  RRID:CVCL_7256
  
  DOI: 10.1016/j.isci.2023.107734
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10480778/
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AI-2 quorum sensing controlled delivery of cytolysin-A by tryptophan auxotrophic low-endotoxic Salmonella and its anticancer effects in CT26 mice with colon cancer

1
1. scibot 08 Sep 2023
  
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  RRID:CVCL_7256
  
  DOI: 10.1016/j.jare.2023.09.003
  
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S-531011, a Novel Anti-Human CCR8 Antibody, Induces Potent Antitumor Responses through Depletion of Tumor-Infiltrating CCR8-Expressing Regulatory T Cells

1
1. scibot 07 Sep 2023
  
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  RRID:CVCL_7256
  
  DOI: 10.1158/1535-7163.MCT-22-0570
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10477828/
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Enhancing CAR T-cell Therapy Using Fab-Based Constitutively Heterodimeric Cytokine Receptors

1
1. scibot 07 Sep 2023
  
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  RRID:CVCL_7256
  
  DOI: 10.1158/2326-6066.CIR-22-0640
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10472109/
Aug 2023
dx.doi.org dx.doi.org

NL-201 upregulates MHC-I expression and intratumoral TCR diversity, and demonstrates robust antitumor activity as monotherapy and in combination with PD-1 blockade

1
1. scibot 09 Aug 2023
  
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  RRID:CVCL_7256
  
  DOI: 10.1158/2326-6066.CIR-22-0304
  
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dx.doi.org/10.1158/2326-6066.CIR-22-0304
Jul 2023
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Mechanical manipulation of cancer cell tumorigenicity via heat shock protein signaling

1
1. scibot 12 Jul 2023
  
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  RRID:CVCL_7256
  
  DOI: 10.1126/sciadv.adg9593
  
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Enhanced bypass of PD-L1 translation reduces the therapeutic response to mTOR kinase inhibitors

2
1. scibot 08 Jul 2023
  
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  RRID:CVCL_7256
  
  DOI: 10.1016/j.celrep.2023.112764
  
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2. scibot 08 Jul 2023
  
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  RRID:CVCL_7256
  
  DOI: 10.1016/j.celrep.2023.112764
  
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sciencedirect.com/science/article/pii/S2211124723007751
May 2023
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Targeting stromal cell sialylation reverses T cell-mediated immunosuppression in the tumor microenvironment

1
1. scibot 11 May 2023
  
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  RRID:CVCL_7256
  
  DOI: 10.1016/j.celrep.2023.112475
  
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onlinelibrary.wiley.com onlinelibrary.wiley.com

Intracellular Adhesion Molecule-1 Improves Responsiveness to Immune Checkpoint Inhibitor by Activating CD8+ T Cells

1
1. scibot 02 May 2023
  
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  RRID:CVCL_7256
  
  DOI: 10.1002/advs.202204378
  
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onlinelibrary.wiley.com/doi/10.1002/advs.202204378
Apr 2023
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An optimized IL-12-Fc expands its therapeutic window, achieving strong activity against mouse tumors at tolerable drug doses

1
1. scibot 14 Apr 2023
  
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  RRID:CVCL_7256
  
  DOI: 10.1016/j.medj.2023.03.007
  
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sciencedirect.com/science/article/pii/S2666634023001034
Mar 2023
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Tissue-resident Lachnospiraceae family bacteria protect against colorectal carcinogenesis by promoting tumor immune surveillance

1
1. scibot 10 Mar 2023
  
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  RRID:CVCL_7256
  
  DOI: 10.1016/j.chom.2023.01.013
  
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Linoleic acid potentiates CD8+ T cell metabolic fitness and antitumor immunity

1
1. scibot 10 Mar 2023
  
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  RRID:CVCL_7256
  
  DOI: 10.1016/j.cmet.2023.02.013
  
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sciencedirect.com/science/article/pii/S1550413123000499
Feb 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Evolved bacterial resistance to the chemotherapy gemcitabine modulates its efficacy in co-cultured cancer cells

1
1. scibot 17 Feb 2023
  
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  RRID:CVCL_7256
  
  DOI: 10.7554/eLife.83140
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9931390/
Jan 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

AZD4625 is a Potent and Selective Inhibitor of KRASG12C

1
1. scibot 12 Jan 2023
  
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  RRID:CVCL_7256
  
  DOI: 10.1158/1535-7163.MCT-22-0241
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9538594/
www.cell.com www.cell.com

Genetic and pharmacological modulation of DNA mismatch repair heterogeneous tumors promotes immune surveillance

1
1. scibot 02 Jan 2023
  
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  RRID:CVCL_7256
  
  DOI: 10.1016/j.ccell.2022.12.003
  
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cell.com/cancer-cell/fulltext/S1535-6108(22)00589-X
Dec 2022
www.nature.com www.nature.com

Table 1 Tumor cell lines used to set up common subcutaneous mouse tumor models

1
1. scibot 02 Dec 2022
  
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  CVCL_7256
  
  DOI: 10.1038/s41596-022-00709-3
  
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nature.com/articles/s41596-022-00709-3/tables/1
Nov 2022
aacrjournals.org aacrjournals.org

Potent and selective PTDSS1 inhibitors induce collateral lethality in cancers with PTDSS2 deletion

1
1. scibot 22 Nov 2022
  
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  RRID:CVCL_7256
  
  DOI: 10.1158/0008-5472.CAN-22-1006
  
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aacrjournals.org/cancerres/article/82/21/4031/709946/Potent-and-Selective-PTDSS1-Inhibitors-Induce
www.tandfonline.com www.tandfonline.com

Study of FA12 peptide-modified PEGylated liposomal doxorubicin (PLD) as an effective ligand to target Muc1 in mice bearing C26 colon carcinoma: in silico, in vitro, and in vivo study

1
1. scibot 17 Nov 2022
  
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  RRID:CVCL_7256
  
  DOI: 10.1080/17425247.2022.2147505
  
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tandfonline.com/doi/full/10.1080/17425247.2022.2147505
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CCL22-based peptide vaccines induce anti-cancer immunity by modulating tumor microenvironment

1
1. scibot 10 Nov 2022
  
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  RRID:CVCL_7256
  
  DOI: 10.1080/2162402X.2022.2115655
  
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tandfonline.com/doi/full/10.1080/2162402X.2022.2115655
Oct 2022
52.53.155.43 52.53.155.43

can-22-1006-html.html

1
1. scibot 27 Oct 2022
  
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  RRID:CVCL_7256
  
  DOI: 10.1158/0008-5472.can-22-1006
  
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52.53.155.43/c7dd388c408138b6cb565cf3908ca9cf1e84b78d/can-22-1006-html.html
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Continuous sensing of IFNα by hepatic endothelial cells shapes a vascular antimetastatic barrier

1
1. scibot 27 Oct 2022
  
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  CVCL_7256
  
  DOI: 10.7554/eLife.80690
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9596162/
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Peroxynitrite in the tumor microenvironment changes the profile of antigens allowing escape from cancer immunotherapy

1
1. scibot 11 Oct 2022
  
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  RRID: CVCL_7256
  
  DOI: 10.1016/j.ccell.2022.09.001
  
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sciencedirect.com/science/article/pii/S1535610822003932
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Targeting telomerase reverse transcriptase with the covalent inhibitor NU-1 confers immunogenic radiation sensitization

1
1. scibot 07 Oct 2022
  
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  CRL-2638
  
  DOI: 10.1016/j.chembiol.2022.09.002
  
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sciencedirect.com/science/article/pii/S2451945622003506
Sep 2022
www.tandfonline.com www.tandfonline.com

CCL22-based peptide vaccines induce anti-cancer immunity by modulating tumor microenvironment

1
1. scibot 02 Sep 2022
  
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  RRID:CVCL_7256
  
  DOI: 10.1080/2162402X.2022.2115655
  
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tandfonline.com/doi/full/10.1080/2162402X.2022.2115655
Aug 2022
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Tumor-infiltrated activated B cells suppress liver metastasis of colorectal cancers

1
1. scibot 31 Aug 2022
  
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  RRID:CVCL_7256
  
  DOI: 10.1016/j.celrep.2022.111295
  
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sciencedirect.com/science/article/pii/S2211124722011159
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Tumor targeted 4-1BB agonist antibody-albumin fusions with high-affinity to FcRn induce anti-tumor immunity without toxicity

1
1. scibot 30 Aug 2022
  
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  RRID:CVCL_7256
  
  DOI: 10.1016/j.isci.2022.104958
  
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sciencedirect.com/science/article/pii/S2589004222012305
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Cytotoxicity and molecular-docking approach of a new rosane-type diterpenoid from the roots of Euphorbia nematocypha

1
1. scibot 26 Aug 2022
  
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  RRID:CVCL_7256
  
  DOI: 10.3389/fchem.2022.912738
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9393309/
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SHMT2-mediated mitochondrial serine metabolism drives 5-FU resistance by fueling nucleotide biosynthesis

1
1. scibot 17 Aug 2022
  
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  ATCCCat# CRL-2638
  
  DOI: 10.1016/j.celrep.2022.111233
  
  Resource: (ATCC Cat# CRL-2638, RRID:CVCL_7256)
  
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sciencedirect.com/science/article/pii/S2211124722010506
www.nature.com www.nature.com

A rapid screening platform to coculture bacteria within tumor spheroids

1
1. scibot 02 Aug 2022
  
  in Public
  
  RRID:CVCL_7256
  
  DOI: 10.1038/s41596-022-00723-5
  
  Resource: (ATCC Cat# CRL-2638, RRID:CVCL_7256)
  
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nature.com/articles/s41596-022-00723-5
Jul 2022
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Nanocarriers based on bacterial membrane materials for cancer vaccine delivery

1
1. scibot 27 Jul 2022
  
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  RRID:CVCL_7256
  
  DOI: 10.1038/s41596-022-00713-7
  
  Resource: (ATCC Cat# CRL-2638, RRID:CVCL_7256)
  
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nature.com/articles/s41596-022-00713-7
Jun 2022
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Optimal target saturation of ligand-blocking anti-GITR antibody IBI37G5 dictates FcγR-independent GITR agonism and antitumor activity

1
1. scibot 22 Jun 2022
  
  in Public
  
  ATCCCat#CRL-2638
  
  DOI: 10.1016/j.xcrm.2022.100660
  
  Resource: (ATCC Cat# CRL-2638, RRID:CVCL_7256)
  
  Curator: @sophiastull
  
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sciencedirect.com/science/article/pii/S2666379122001926
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Androgens drive sexual dimorphism in liver metastasis by promoting hepatic accumulation of neutrophils

1
1. scibot 22 Jun 2022
  
  in Public
  
  RRID:CVCL_7256
  
  DOI: 10.1016/j.celrep.2022.110987
  
  Resource: (ATCC Cat# CRL-2638, RRID:CVCL_7256)
  
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RNF31 inhibition sensitizes tumors to bystander killing by innate and adaptive immune cells

1
1. scibot 10 Jun 2022
  
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  RRID:CVCL_7256
  
  DOI: 10.1016/j.xcrm.2022.100655
  
  Resource: (ATCC Cat# CRL-2638, RRID:CVCL_7256)
  
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Leucine-tRNA-synthase-2-expressing B cells contribute to colorectal cancer immunoevasion

1
1. scibot 09 Jun 2022
  
  in Public
  
  ATCCCat# CRL2638
  
  DOI: 10.1016/j.immuni.2022.04.017
  
  Resource: (ATCC Cat# CRL-2638, RRID:CVCL_7256)
  
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Flow cytometry analysis of endothelial cells and subsets of exhausted CD8+ T cells in murine tumor models

1
1. scibot 09 Jun 2022
  
  in Public
  
  ATCC CRL-2638
  
  DOI: 10.1016/j.xpro.2022.101444
  
  Resource: (ATCC Cat# CRL-2638, RRID:CVCL_7256)
  
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Formulation of two lipid-based membrane–core nanoparticles for FOLFOX combination therapy

1
1. scibot 04 Jun 2022
  
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  RRID:CVCL_7256
  
  DOI: 10.1038/s41596-022-00698-3
  
  Resource: (ATCC Cat# CRL-2638, RRID:CVCL_7256)
  
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nature.com/articles/s41596-022-00698-3
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Intracellular complement C5a/C5aR1 stabilizes β-catenin to promote colorectal tumorigenesis

1
1. scibot 02 Jun 2022
  
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  ATCCCat#CRL-2638
  
  DOI: 10.1016/j.celrep.2022.110851
  
  Resource: (ATCC Cat# CRL-2638, RRID:CVCL_7256)
  
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May 2022
pubs.acs.org pubs.acs.org

Simultaneous Delivery of Doxorubicin and Protease Inhibitor Derivative to Solid Tumors via Star-Shaped Polymer Nanomedicines Overcomes P-gp- and STAT3-Mediated Chemoresistance

1
1. scibot 24 May 2022
  
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  RRID:CVCL_7256
  
  DOI: 10.1021/acs.biomac.2c00256
  
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pubs.acs.org/doi/full/10.1021/acs.biomac.2c00256
Apr 2022
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Context-Dependent Immunomodulatory Effects of MEK Inhibition are Enhanced with T-cell Agonist Therapy

1
1. scibot 02 Apr 2022
  
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  RRID:CVCL_7256
  
  DOI: 10.1158/2326-6066.CIR-21-0147
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8492503/
Mar 2022
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Mechanistic convergence of the TIGIT and PD-1 inhibitory pathways necessitates co-blockade to optimize anti-tumor CD8+ T cell responses

1
1. scibot 09 Mar 2022
  
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  RRID:CRL-2638
  
  DOI: 10.1016/j.immuni.2022.02.005
  
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Activating Mucosal-Associated Invariant T cells Induces a Broad Antitumor Response

1
1. scibot 04 Mar 2022
  
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  RRID:CVCL_7256
  
  DOI: 10.1158/2326-6066.CIR-20-0925
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8416791/
Feb 2022
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Tumor-associated high endothelial venules mediate lymphocyte entry into tumors and predict response to PD-1 plus CTLA-4 combination immunotherapy

1
1. scibot 04 Feb 2022
  
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  ATCC CRL-2638
  
  DOI: 10.1016/j.ccell.2022.01.002
  
  Resource: (ATCC Cat# CRL-2638, RRID:CVCL_7256)
  
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Jan 2022
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MEK inhibition overcomes chemoimmunotherapy resistance by inducing CXCL10 in cancer cells

1
1. scibot 26 Jan 2022
  
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  RRID:CVCL_7256
  
  DOI: 10.1016/j.ccell.2021.12.009
  
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Original research: An engineered oncolytic vaccinia virus encoding a single-chain variable fragment against TIGIT induces effective antitumor immunity and synergizes with PD-1 or LAG-3 blockade

1
1. scibot 12 Jan 2022
  
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  CRL-2638
  
  DOI: 10.1136/jitc-2021-002843
  
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  Curator: @evieth
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8705214/
Nov 2021
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The allergy mediator histamine confers resistanceto immunotherapy in cancer patients via activationof the macrophage histamine receptor H1

1
1. scibot 25 Nov 2021
  
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  RRID:CVCL_7256
  
  DOI: 10.1016/j.ccell.2021.11.002
  
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52.53.155.43 52.53.155.43

ajpgi.00114.2021-html.html

1
1. scibot 24 Nov 2021
  
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  CVCL_7256
  
  DOI: 10.1152/ajpgi.00114.2021
  
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52.53.155.43/e404321d0816ed8b6be76f0b920f44bac067ee21/ajpgi.00114.2021-html.html
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Myeloid cell subsets that express latency-associated peptide promote cancer growth by modulating T cells

1
1. scibot 18 Nov 2021
  
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  RRID:CVCL_7256
  
  DOI: 10.1016/j.isci.2021.103347
  
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sciencedirect.com/science/article/pii/S258900422101316X
Aug 2021
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Commensal Clostridiales strains mediate effective anti-cancer immune response against solid tumors

1
1. scibot 28 Aug 2021
  
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  RRID:CVCL_7256
  
  DOI: 10.1016/j.chom.2021.08.001
  
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sciencedirect.com/science/article/pii/S1931312821003772
jitc.bmj.com jitc.bmj.com

Novel oncolytic adenovirus expressing enhanced cross-hybrid IgGA Fc PD-L1 inhibitor activates multiple immune effector populations leading to enhanced tumor killing in vitro, in vivo and with patient-derived tumor organoids

1
1. scibot 16 Aug 2021
  
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  RRID:CVCL_7256
  
  DOI: 10.1136/jitc-2021-003000
  
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jitc.bmj.com/content/9/8/e003000
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Untitled document

1
1. scibot 10 Aug 2021
  
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  RRID:CVCL_7256
  
  DOI: 10.1016/j.ebiom.2018.09.050
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6284351/
elifesciences.org elifesciences.org

Blockade of the LRP16-PKR-NF-κB signaling axis sensitizes colorectal carcinoma cells to DNA-damaging cytotoxic therapy

1
1. scibot 02 Aug 2021
  
  in Public
  
  RRID:CVCL_7256
  
  DOI: 10.7554/eLife.27301
  
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elifesciences.org/articles/27301
Jul 2021
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DeSUMOylase SENP7-Mediated Epithelial Signaling Triggers Intestinal Inflammation via Expansion of Gamma-Delta T Cells

1
1. scibot 31 Jul 2021
  
  in Public
  
  CT26 cells
  
  DOI: 10.1016/j.celrep.2019.11.028
  
  Resource: (ATCC Cat# CRL-2638, RRID:CVCL_7256)
  
  Curator: @ethanbadger
  
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Expression of Enterocin-P in HEK Platform: Evaluation of Its Cytotoxic Effects on Cancer Cell Lines and Its Potency to Interact with Cell-Surface Glycosaminoglycan by Molecular Modeling

1
1. scibot 29 Jul 2021
  
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  ATCC CRL-2638
  
  DOI: 10.1007/s10989-019-09956-7
  
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  RRID:CVCL_7256 RRIDCUR:Unrecognized
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link.springer.com/article/10.1007/s10989-019-09956-7
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Type I Interferon Delivery by iPSC-Derived Myeloid Cells Elicits Antitumor Immunity via XCR1+ Dendritic Cells

1
1. scibot 29 Jul 2021
  
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  RRID:CVCL_7256
  
  DOI: 10.1016/j.celrep.2019.08.086
  
  Resource: (ATCC Cat# CRL-2638, RRID:CVCL_7256)
  
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sciencedirect.com/science/article/pii/S2211124719311489
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Ligand-Blocking and Membrane-Proximal Domain Targeting Anti-OX40 Antibodies Mediate Potent T Cell-Stimulatory and Anti-Tumor Activity

1
1. scibot 28 Jul 2021
  
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  CT26 cells
  
  DOI: 10.1016/j.celrep.2019.05.027
  
  Resource: (ATCC Cat# CRL-2638, RRID:CVCL_7256)
  
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sciencedirect.com/science/article/pii/S2211124719306382
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PARP7 negatively regulates the type I interferon response in cancer cells and its inhibition triggers antitumor immunity

1
1. scibot 23 Jul 2021
  
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  CRL-2638
  
  DOI: 10.1016/j.ccell.2021.06.018
  
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sciencedirect.com/science/article/pii/S1535610821003408
Jun 2021
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Pharmacologic modulation of RNA splicing enhances anti-tumor immunity

1
1. scibot 25 Jun 2021
  
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  CRL-2638
  
  DOI: 10.1016/j.cell.2021.05.038
  
  Resource: (ATCC Cat# CRL-2638, RRID:CVCL_7256)
  
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sciencedirect.com/science/article/pii/S0092867421006905
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Expansion of tumor-associated Treg cells upon disruption of a CTLA-4-dependent feedback loop

1
1. scibot 22 Jun 2021
  
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  CRL-2638
  
  DOI: 10.1016/j.cell.2021.05.027
  
  Resource: (ATCC Cat# CRL-2638, RRID:CVCL_7256)
  
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sciencedirect.com/science/article/pii/S0092867421006577
May 2021
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An Oncogenic Alteration Creates a Microenvironment that Promotes Tumor Progression by Conferring a Metabolic Advantage to Regulatory T Cells

1
1. scibot 15 May 2021
  
  in Public
  
  CRL-2638
  
  DOI: 10.1016/j.immuni.2020.06.016
  
  Resource: (ATCC Cat# CRL-2638, RRID:CVCL_7256)
  
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  RRID:CVCL_7256 RRIDCUR:Missing
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sciencedirect.com/science/article/pii/S1074761320302715
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Role of nuclear localization in the regulation and function of T-bet and Eomes in exhausted CD8 T cells

1
1. scibot 12 May 2021
  
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  RRID:CVCL_7256
  
  DOI: 10.1016/j.celrep.2021.109120
  
  Resource: (ATCC Cat# CRL-2638, RRID:CVCL_7256)
  
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pmc.ncbi.nlm.nih.gov/articles/PMC8195461/
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Polymer-ritonavir derivate nanomedicine with pH-sensitive activation possesses potent anti-tumor activity in vivo via inhibition of proteasome and STAT3 signaling

1
1. scibot 07 May 2021
  
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  RRID:CVCL_7256
  
  DOI: 10.1016/j.jconrel.2021.03.015
  
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sciencedirect.com/science/article/pii/S0168365921001267
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Extracellular matrix in multicellular aggregates acts as a pressure sensor controlling cell proliferation and motility

1
1. scibot 01 May 2021
  
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  RRID:CVCL_7256
  
  DOI: 10.7554/eLife.63258
  
  Resource: (ATCC Cat# CRL-2638, RRID:CVCL_7256)
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8064752/
Apr 2021
www.cell.com www.cell.com

Obesity Shapes Metabolism in the Tumor Microenvironment to Suppress Anti-Tumor Immunity

1
1. scibot 24 Apr 2021
  
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  RRID:CVCL_7256
  
  DOI: 10.1016/j.cell.2020.11.009
  
  Resource: (ATCC Cat# CRL-2638, RRID:CVCL_7256)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_7256
  
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cell.com/cell/fulltext/S0092-8674(20)31526-9
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An optimized protocol for patient-derived xenograft in humanized mice to evaluate the role of IL-34 in immunotherapeutic resistance

1
1. scibot 10 Apr 2021
  
  in Public
  
  CRL-2638
  
  DOI: 10.1016/j.xpro.2021.100460
  
  Resource: (ATCC Cat# CRL-2638, RRID:CVCL_7256)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:CVCL_7256
  
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  RRID:CVCL_7256 RRIDCUR:Missing
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sciencedirect.com/science/article/pii/S2666166721001672
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Creatine promotes cancer metastasis through activation of Smad2/3

1
1. scibot 06 Apr 2021
  
  in Public
  
  Cat#CRL-2638
  
  DOI: 10.1016/j.cmet.2021.03.009
  
  Resource: (ATCC Cat# CRL-2638, RRID:CVCL_7256)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:CVCL_7256
  
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  RRID:CVCL_7256 RRIDCUR:Missing
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sciencedirect.com/science/article/pii/S1550413121001169
Feb 2021
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Enhanced antitumor efficacy of a novel oncolytic vaccinia virus encoding a fully monoclonal antibody against T-cell immunoglobulin and ITIM domain (TIGIT)

1
1. scibot 24 Feb 2021
  
  in Public
  
  RRID:CVCL_7256
  
  DOI: 10.1016/j.ebiom.2021.103240
  
  Resource: (ATCC Cat# CRL-2638, RRID:CVCL_7256)
  
  Curator: @evieth
  
  SciCrunch record: RRID:CVCL_7256
  
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  RRID:CVCL_7256 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S2352396421000335
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MyD88 in myofibroblasts enhances colitis-associated tumorigenesis via promoting macrophage M2 polarization

1
1. scibot 09 Feb 2021
  
  in Public
  
  CT26 cells
  
  DOI: 10.1016/j.celrep.2021.108724
  
  Resource: (ATCC Cat# CRL-2638, RRID:CVCL_7256)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:CVCL_7256
  
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  RRIDCUR:Missing RRID:CVCL_7256
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sciencedirect.com/science/article/pii/S2211124721000371
Sep 2020
cancerimmunolres.aacrjournals.org cancerimmunolres.aacrjournals.org

Anti-VEGF Treatment Enhances CD8+ T-Cell Antitumor Activity by Amplifying Hypoxia

1
1. scibot 26 Sep 2020
  
  in Public
  
  RRID:CVCL_7256
  
  DOI: 10.1158/2326-6066.CIR-19-0360
  
  Resource: (ATCC Cat# CRL-2638, RRID:CVCL_7256)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:CVCL_7256
  
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  RRIDCUR:Validated RRID:CVCL_7256
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cancerimmunolres.aacrjournals.org/content/8/6/806
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Endocytosis Inhibition in Humans to Improve Responses to ADCC-Mediating Antibodies

1
1. scibot 16 Sep 2020
  
  in Public
  
  RRID:CVCL_7256
  
  DOI: 10.1016/j.cell.2020.02.019
  
  Resource: (ATCC Cat# CRL-2638, RRID:CVCL_7256)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:CVCL_7256
  
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  RRIDCUR:Validated RRID:CVCL_7256
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cell.com/cell/fulltext/S0092-8674(20)30163-X
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Selective targeting of the TLR4 co-receptor, MD2, prevents colon cancer growth and lung metastasis

1
1. scibot 13 Sep 2020
  
  in Public
  
  CVCL_7256
  
  DOI: 10.7150/ijbs.39098
  
  Resource: (ATCC Cat# CRL-2638, RRID:CVCL_7256)
  
  Curator: @evieth
  
  SciCrunch record: RRID:CVCL_7256
  
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  RRID:CVCL_7256 RRIDCUR:Validated
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ncbi.nlm.nih.gov/pmc/articles/PMC7085228/
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PCK1 and DHODH drive colorectal cancer liver metastatic colonization and hypoxic growth by promoting nucleotide synthesis

1
1. scibot 06 Sep 2020
  
  in Public
  
  RRID:CVCL_7256
  
  DOI: 10.7554/eLife.52135
  
  Resource: (ATCC Cat# CRL-2638, RRID:CVCL_7256)
  
  Curator: @evieth
  
  SciCrunch record: RRID:CVCL_7256
  
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  RRIDCUR:Validated RRID:CVCL_7256
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ncbi.nlm.nih.gov/pmc/articles/PMC7299340/
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Baseline Frequency of Inflammatory Cxcl9-Expressing Tumor-Associated Macrophages Predicts Response to Avelumab Treatment

1
1. scibot 03 Sep 2020
  
  in Public
  
  CRL-2638
  
  DOI: 10.1016/j.celrep.2020.107873
  
  Resource: (ATCC Cat# CRL-2638, RRID:CVCL_7256)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:CVCL_7256
  
  Curator comments: CT26.WT cell line ATCC Cat# CRL-2638
  
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  RRID:CVCL_7256 RRIDCUR:Missing
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sciencedirect.com/science/article/pii/S2211124720308548
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Cyto-Immuno-Therapy for Cancer: A Pathway Elicited by Tumor-Targeted, Cytotoxic Drug-Packaged Bacterially Derived Nanocells

1
1. scibot 03 Sep 2020
  
  in Public
  
  RRID:CVCL_7256
  
  DOI: 10.1016/j.ccell.2020.02.001
  
  Resource: (ATCC Cat# CRL-2638, RRID:CVCL_7256)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:CVCL_7256
  
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  RRID:CVCL_7256 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S1535610820300908
Jan 2020
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TCF-1-Centered Transcriptional Network Drives an Effector versus Exhausted CD8 T Cell-Fate Decision

1
1. scibot 13 Jan 2020
  
  in Public
  
  RRID:CVCL_7256
  
  DOI: 10.1016/j.immuni.2019.09.013
  
  Resource: (ATCC Cat# CRL-2638, RRID:CVCL_7256)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:CVCL_7256
  
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  RRID:CVCL_7256 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S1074761319304091
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Mutations in an Innate Immunity Pathway Are Associated with Poor Overall Survival Outcomes and Hypoxic Signaling in Cancer

1
1. scibot 13 Jan 2020
  
  in Public
  
  RRID:CVCL_7256
  
  DOI: 10.1016/j.celrep.2018.11.093
  
  Resource: (ATCC Cat# CRL-2638, RRID:CVCL_7256)
  
  Curator: @evieth
  
  SciCrunch record: RRID:CVCL_7256
  
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  RRID:CVCL_7256 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S2211124718318849
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Targeting TMEM176B Enhances Antitumor Immunity and Augments the Efficacy of Immune Checkpoint Blockers by Unleashing Inflammasome Activation

1
1. scibot 13 Jan 2020
  
  in Public
  
  CVCL_7256
  
  DOI: 10.1016/j.ccell.2019.04.003
  
  Resource: (ATCC Cat# CRL-2638, RRID:CVCL_7256)
  
  Curator: @ethanbadger
  
  SciCrunch record: CVCL_7256
  
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  RRID:CVCL_7256 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S1535610819301989
Nov 2018
www.sciencedirect.com www.sciencedirect.com

Untitled document

1
1. scibot 05 Nov 2018
  
  in Public
  
  RRID:CVCL_7256
  
  Resource used:
  
  (BCRC Cat# 60447, RRID:CVCL_7256)
  
  SciCrunch record: RRID:CVCL_7256
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
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sciencedirect.com/science/article/pii/S2352396418304092
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Metformin Promotes Antitumor Immunity via Endoplasmic-Reticulum-Associated Degradation of PD-L1

1
1. scibot 05 Nov 2018
  
  in Public
  
  CRL-2638
  
  Curator: @Jmenke
  
  Resource used:
  
  (BCRC Cat# 60447, RRID:CVCL_7256)
  
  SciCrunch record: RRID:CVCL_7256
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
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  RRID:CVCL_7256 RRIDCUR:Missing
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sciencedirect.com/science/article/pii/S1097276518305999
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IKZF1 Enhances Immune Infiltrate Recruitment in Solid Tumors and Susceptibility to Immunotherapy

1
1. scibot 05 Nov 2018
  
  in Public
  
  CRL-2638
  
  Curator: @Jmenke
  
  Resource used:
  
  (BCRC Cat# 60447, RRID:CVCL_7256)
  
  SciCrunch record: RRID:CVCL_7256
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
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  RRID:CVCL_7256 RRIDCUR:Missing
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sciencedirect.com/science/article/pii/S2405471218302382
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Twist1 Activation in Muscle Progenitor Cells Causes Muscle Loss Akin to Cancer Cachexia

1
1. scibot 05 Nov 2018
  
  in Public
  
  CRL-2638
  
  Curator: @Jmenke
  
  Resource used:
  
  (BCRC Cat# 60447, RRID:CVCL_7256)
  
  SciCrunch record: RRID:CVCL_7256
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
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  RRID:CVCL_7256 RRIDCUR:Missing
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sciencedirect.com/science/article/pii/S1534580718304192
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Selective FcγR Co-engagement on APCs Modulates the Activity of Therapeutic Antibodies Targeting T Cell Antigens

1
1. scibot 05 Nov 2018
  
  in Public
  
  RRID:CVCL_7256
  
  Resource used:
  
  (BCRC Cat# 60447, RRID:CVCL_7256)
  
  SciCrunch record: RRID:CVCL_7256
  
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sciencedirect.com/science/article/pii/S1535610818302198
Nov 2017
www.sciencedirect.com www.sciencedirect.com

YAP/TAZ Orchestrate VEGF Signaling during Developmental Angiogenesis

1
1. scibot 08 Nov 2017
  
  in Public
  
  CRL2638
  
  Curator: @Jmenke
  
  Resource used:
  
  (BCRC Cat# 60447, RRID:CVCL_7256)
  
  SciCrunch record: RRID:CVCL_7256
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
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  RRID:CVCL_7256 RRIDCUR:Missing
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sciencedirect.com/science/article/pii/S1534580717306305
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A Distinct Gene Module for Dysfunction Uncoupled from Activation in Tumor-Infiltrating T Cells

1
1. scibot 08 Nov 2017
  
  in Public
  
  CVCL_7256
  
  Curator: @gabimpine
  
  Resource used:
  
  (BCRC Cat# 60447, RRID:CVCL_7256)
  
  SciCrunch record: RRID:CVCL_7256
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
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  RRID:CVCL_7256 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S0092867416311497

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