Although humans and Earth seem to be noncontiguous,perhaps we are contiguous in a way that we have not yet learned to perceive.

Modulating these many pathways requires alteration of expression of a diverse array of genes, which takes place via the coordinated action of various stress-responsive transcription factors as well as chromatin-associated factors. While there is some understanding regarding the role of transcription factors, enzymes catalyzing covalent histone modifications and chromatin remodeling complexes in responses to various abiotic stresses in plants (Sahoo et al., 2013; Kim et al., 2015), the role of histone chaperones in stress response remains enigmatic