By default: no. The Auto-Type method in KeePass 2.x works the same as the one in 1.x and consequently is not keylogger-safe. However, KeePass features an alternative method called Two-Channel Auto-Type Obfuscation (TCATO), which renders keyloggers useless. This is an opt-in feature (because it doesn't work with all windows) and must be enabled for entries manually. See the TCATO documentation for details.