Abstract
General / Study Terms
AHN – Adult Hippocampal Neurogenesis
AD – Alzheimer’s Disease
PMD – Post-Mortem Delay
DG – Dentate Gyrus
DGC – Dentate Granule Cell
GCL – Granule Cell Layer
ML – Molecular Layer
SGZ – Subgranular Zone
H – Hilus
EC – Entorhinal Cortex
CA1, CA3 – Cornu Ammonis hippocampal subfields
Pyr – Pyramidal layer
Cell Markers & Proteins
DCX – Doublecortin (marker of immature neurons)
Prox1 – Prospero Homeobox 1 (granule cell fate marker)
PSA-NCAM – Polysialic Acid–Neural Cell Adhesion Molecule (immature neuron marker)
CR – Calretinin (calcium-binding protein; early immature neuron marker)
CB – Calbindin (calcium-binding protein; marker of more mature neurons)
NeuN – Neuronal Nuclei (marker of mature neurons)
βIII-tubulin – Cytoskeletal protein (neuronal identity marker)
Tau (pTau) – Microtubule-associated protein; phosphorylated tau linked to AD pathology
β-amyloid (Aβ) – Amyloid-beta peptide, forms plaques in AD
Methods & Technical
NaBH₄ – Sodium borohydride (used in tissue treatment)
HC-AR – Heat and Chemical Antigen Retrieval (histological technique)
CI – Confidence Interval
ANOVA – Analysis of Variance (statistical test)
s.e.m. – Standard Error of the Mean
