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  1. Oct 2020
  2. Sep 2020
  3. covid19-civiclytics.citibeats.com covid19-civiclytics.citibeats.com
    1. tren_topic,social_media_traker

      Percepciones y preocupaciones que expresan los latinoamericanos y caribeños en Internet respecto COVID-19

      Medidas de crisis Seguridad alimentaria Seguridad econ. (hogares) Seg. econ. (empresas) Seguridad sanitaria Impacto cultural Teletrabajo Educación Salud mental Personas en vulnerabilidad Medioambiente Iniciativas ciudadanas Noticias falsas

  4. Apr 2020
  5. Mar 2020
  6. www.facebook.com www.facebook.com
    A recent paper has shown that novel coronavirus 2019-nCoV uses the SARS-coronavirus receptor ACE2 and the transmembrane protease serine-2 (TMPRSS2) for entering the target cells (https://www.biorxiv.org/content/10.1101/2020.01.31.929042v1?fbclid=IwAR2pEpKv1VN3o2zjUD0RjguQFtspH0nb5qhvYUt3z1evyNwVYFI-A1ylumU). Today we would like to share with you what kind of information is contained on ACE2 in another database, BRENDA™, which we distribute. According to the record in BRENDA™, ACE2 is associated with quite a number of diseases in human, among them heart failure, hypertension, acute lung injury, infections (associated with SARS & influenza). The record mentions about 100 inhibitors; for some even the concentration used in experiment and the amount of inhibition is provided directly. ACE2 exists as membrane-bound and as a soluble form. The latter is generated by cleavage of the membrane-bound form (Brenda ref 707074 =PMID 19411314). In case of the SARS-associated coronavirus (SARS-CoV) the membrane-bound form of ACE2 serves as virus receptor in vitro, and shedding is not required for infection to occur. The transmembrane protease serine-2 (TMPRSS2) has found to activate the spike protein of the SARS-CoV and to positively affect entry of the virus. Many more challenging and thrilling findings will have to be made to completely elucidate all facets of the 2019-nCoV novel coronavirus and its action. We hope very much that powerful information resources, like the databases of our portfolio, will contribute to this fight. #coronavirus #Covid19 #Covid_19 #2019nCoV #BRENDA #geneXplain