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  1. Nov 2024
    1. I would say the epigenetic inheritance that has to occur there and how it occurs must be contributing a very large fraction indeed to the differentiation process

      for - answer - Denis Noble - to Michael Levin - question - What percentage of genetic vs non-genetic information passed down to germ line from embryogenesis onwards ? - a very large fraction is epigenetic inheritance indeed.

    2. what percentage of the information that is used by an organism let's say embryogenesis onwards is genetic versus all other sources put together what what what would you guess as a as a breakdown

      for - question - Michael Levin to - Denis Noble - percentage of genetic vs non-genetic information passed down to germ line from embryogenesis onwards

    3. the only way you can visualize the vaces because they're too tiny to be visualized by standard microscopy labeling with florescent dyes is about the only way we can um easily identify what molecules have been passed down from the vesicles to The Germ cells but that's very restrictive you see because there will be millions of different molecules in a single visle to be faced with only being able to label three or four of those otherwise we can't make out the the differences is it's very tedious

      for - evolution - work to identify non-DNA information passed down to germ line - millions of permutations - fluorescence technique applied to only a few at a time - tedious work - Denis Noble

  2. Nov 2016
    1. : t(27) = 2.66, p<0.05)

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    2. t(27) = 5.31, p<0.01)

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    3. t(44) = 3.10, p<0.05;

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    4. vs. t(72) = 3.07, p<0.05)

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    5. t(27) = 3.12, p<0.05)

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    6. t(55) = 2.02, p<0.05)

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    7. Corresponding author

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    8. References

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    10. Irino & Tada 2009)

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    11. Lee and Sherman, 2011)

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    12. Sherman and Guillery, 1998)

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    13. Groenewegen and Berendse, 1994;

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    14. Golding et al., 2002)

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    15. Popescu et al., 2007)

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    16. Pakhotin and Bracci, 2007)

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    17. Pawlak and Kerr, 2008)

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    18. Surmeier et al., 2007;

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    19. Calabresi et al., 2007;

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    20. Mahon et al., 2004;

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    21. Kreitzer and Malenka, 2007;

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    22. Kreitzer and Malenka, 2008)

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    23. Losonczy et al., 2008)

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    24. Plotkin et al., 2011)

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    25. Nanda et al., 2009)

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    26. Berndt et al., 2011)

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    27. Gunaydin et al., 2010)

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    28. Smeal et al., 2007)

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    29. Ding et al., 2010)

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    30. Kitai et al., 1976;

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    31. Ellender et al., 2011)

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    32. Groenewegen, 1988)

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    33. Herkenham, 1979;

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    34. Krettek and Price, 1977;

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    35. Boyden et al., 2005)

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    36. Smeal et al., 2008)

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    37. Ding et al., 2008;

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    38. Moss and Bolam, 2008;

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    39. Raju et al., 2006;

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    40. Fujiyama et al., 2006;

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    41. Lacey et al., 2005;

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    42. Sidibe and Smith, 1999)

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    43. Rudkin and Sadikot, 1999;

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    44. Lapper and Bolam, 1992;

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    45. Lacey et al., 2007)

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    46. Sadikot et al., 1992;

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    47. Xu et al., 1991;

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    50. Berendse and Groenewegen, 1990;

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    53. Smith et al., 2004;

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    57. Graybiel et al., 1994;

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    58. Our algorithms have identified this as your results section

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    107. Acknowledgements and funding

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    108. Introduction

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    109. You have included an email address

    110. t(72) = 1.73, p<0.05;

      This t-test is consistent with its p-value using a 1 tailed test

    111. : t(27) = 1.99, p<0.05;

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    112. : t(27) = 1.98, p<0.05)

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    113. This looks like an institutional email address

    114. Figure 5: Long term plasticity at Pf, but not CL, synapses

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    115. Figure 3: Dynamic properties of CL, Pf and cortical synapses on MSNs

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    116. Figure 2: The majority of MSNs receive both thalamic and cortical input

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    117. 1: Localized transfection of thalamic neurons in the central lateral or parafascicular thalamic nucleus

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    118. Data Access

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    120. bstract

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    121. 32%

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    122. 30%

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    123. Abbreviated title

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    124. Figure 5A

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    125. Figure 3A

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    127. Figure 1A,

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    128. Discussion

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    129. p=0.02)

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    130. Conflicts of Interests

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    131. Irino, T; Tada, R (2009): Chemical and mineral compositions of sediments from ODP Site 127‐797. Geological Institute, University of Tokyo. http://dx.doi.org/10.1594/PANGAEA.726855

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    132. References

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    133. Acknowledgements and funding

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